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The map label for this gene is yngJ [H]

Identifier: 16126291

GI number: 16126291

Start: 2256755

End: 2257888

Strand: Direct

Name: yngJ [H]

Synonym: CC_2050

Alternate gene names: 16126291

Gene position: 2256755-2257888 (Clockwise)

Preceding gene: 16126290

Following gene: 16126302

Centisome position: 56.18

GC content: 71.16

Gene sequence:

>1134_bases
ATGGCCGTCCTGACCGAAGAACAGACGATGCTGCGCGACGCCGCCAAGGGCTGGGCCAGCGAAAGCGCGCCCGTCGGCGC
CCTGCGCAAGCTGCGCGACAGCAAGAGCAAGCAGACCTTCGACCCCGCCGCCTGGGCCGAGATGGGCCAGATGGGCTGGG
CCGGCGTGATCGTGCCCGAGGCCTATGACGGCTCGGCCTTCGGCTATCTGGGCCTGGGCCTGATCCTGGAAGAGACCGGC
CGGACCCTGGCCGCCTCCCCGCTCCTCTCCACCGCCATGATCGCCGCTTCGGCGCTGCAGCTGGGCGGCTCCGACGCTCA
GAAGCAGGCTTGGCTGCCCAAGATCGCCACCGGCGAGGCCGTGGCGACGCTGGCGATCGACGAAGGCGCTCACCACGCCC
CCGCCCGCACCGCCCTGTCGGCGACCCAAAGCGGCGCAGGCTACGTGCTGAACGGAACCAAGACCCTGGTGCTGGACGGT
GAGGCCGCCGACCTGCTGATCGTTGCGGCCCGCACCAGCGGCGCGCCGGGTGACACCAACGGCATCACCCTGTTCCTCGT
CGCGGGCGACGCCGCCGGCGTGACCCGCTCGCACCTGTCGCTGATCGACTCGCGCGGCGCGGCCAAGATCGCCTTTGACG
GCGTCGAGGTCGGCGCGGACGCGGTGCTGGGCGAGGTCGACAAGGGCTGGGCCGTGCTGGAGCCGACCCTGGACCGCGCC
TATGCGGGCCTCGCCGCCGAGATGCTCGGCAGCGCCAGCGCCGCCTTCGACATCACCCTGGACTACTTGAAGACGCGCAC
CCAGTTCGGCCAGGTCATCGGCACGTTCCAGGCCCTGCAACACCGCGCCGCCAAGTGGTTCACCGACCTGGAGACCACCC
GCTCGTGCGTCGAAGCCGCGCTCGAGGCGCTGGACGCCGGCGCCGACAGCCGCGCGCTGGCCTTTCTGGCCAAGGCCAAG
GCCAGCGAGCTGGTGCACCTGGCGTCGAACGAGATGGTGCAGATGCACGGCGGCATCGGTATGACCGACGCCCACGACGC
CGGCCTGTACATGAAGCGCGCGCGCGTCACCGAGGCCCTGTTCGGCGGGGCCAGCTTCCACCGCGACCGCTATGCGCGCC
TGATGGGATTCTGA

Upstream 100 bases:

>100_bases
GGTCCTGGGCCTTCTGGATCACCAGTAACCCTCCGAACCGTAAGCCGCGCGCGCCGTCGGAACGGCGCGCCAAGACCAAG
ACTTTTCGAGGAGCCTGAAC

Downstream 100 bases:

>100_bases
TCCCGCGACCTGTCAACAAACGGGGGCCGGTCGTCCGAACGGCCCCCGTCTAACTCCAACAGGACTAACGCCGGCGCGCC
GGCGCGGGCGCATGCGCCAG

Product: acyl-CoA dehydrogenase family protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MAVLTEEQTMLRDAAKGWASESAPVGALRKLRDSKSKQTFDPAAWAEMGQMGWAGVIVPEAYDGSAFGYLGLGLILEETG
RTLAASPLLSTAMIAASALQLGGSDAQKQAWLPKIATGEAVATLAIDEGAHHAPARTALSATQSGAGYVLNGTKTLVLDG
EAADLLIVAARTSGAPGDTNGITLFLVAGDAAGVTRSHLSLIDSRGAAKIAFDGVEVGADAVLGEVDKGWAVLEPTLDRA
YAGLAAEMLGSASAAFDITLDYLKTRTQFGQVIGTFQALQHRAAKWFTDLETTRSCVEAALEALDAGADSRALAFLAKAK
ASELVHLASNEMVQMHGGIGMTDAHDAGLYMKRARVTEALFGGASFHRDRYARLMGF

Sequences:

>Translated_377_residues
MAVLTEEQTMLRDAAKGWASESAPVGALRKLRDSKSKQTFDPAAWAEMGQMGWAGVIVPEAYDGSAFGYLGLGLILEETG
RTLAASPLLSTAMIAASALQLGGSDAQKQAWLPKIATGEAVATLAIDEGAHHAPARTALSATQSGAGYVLNGTKTLVLDG
EAADLLIVAARTSGAPGDTNGITLFLVAGDAAGVTRSHLSLIDSRGAAKIAFDGVEVGADAVLGEVDKGWAVLEPTLDRA
YAGLAAEMLGSASAAFDITLDYLKTRTQFGQVIGTFQALQHRAAKWFTDLETTRSCVEAALEALDAGADSRALAFLAKAK
ASELVHLASNEMVQMHGGIGMTDAHDAGLYMKRARVTEALFGGASFHRDRYARLMGF
>Mature_376_residues
AVLTEEQTMLRDAAKGWASESAPVGALRKLRDSKSKQTFDPAAWAEMGQMGWAGVIVPEAYDGSAFGYLGLGLILEETGR
TLAASPLLSTAMIAASALQLGGSDAQKQAWLPKIATGEAVATLAIDEGAHHAPARTALSATQSGAGYVLNGTKTLVLDGE
AADLLIVAARTSGAPGDTNGITLFLVAGDAAGVTRSHLSLIDSRGAAKIAFDGVEVGADAVLGEVDKGWAVLEPTLDRAY
AGLAAEMLGSASAAFDITLDYLKTRTQFGQVIGTFQALQHRAAKWFTDLETTRSCVEAALEALDAGADSRALAFLAKAKA
SELVHLASNEMVQMHGGIGMTDAHDAGLYMKRARVTEALFGGASFHRDRYARLMGF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=365, Percent_Identity=32.3287671232877, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI226958414, Length=362, Percent_Identity=32.3204419889503, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI4501859, Length=382, Percent_Identity=27.7486910994764, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI4501857, Length=327, Percent_Identity=27.82874617737, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=28.8, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI76496475, Length=360, Percent_Identity=28.6111111111111, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4557235, Length=363, Percent_Identity=28.3746556473829, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=26.984126984127, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21361497, Length=332, Percent_Identity=26.8072289156627, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4557231, Length=395, Percent_Identity=24.8101265822785, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI187960098, Length=395, Percent_Identity=24.8101265822785, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4503943, Length=355, Percent_Identity=23.6619718309859, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI7669494, Length=355, Percent_Identity=23.6619718309859, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786223, Length=328, Percent_Identity=23.780487804878, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081958, Length=365, Percent_Identity=23.013698630137, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=31.4666666666667, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=27.4932614555256, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17506239, Length=382, Percent_Identity=28.0104712041885, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71990804, Length=299, Percent_Identity=30.4347826086957, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71985184, Length=321, Percent_Identity=28.3489096573209, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=393, Percent_Identity=25.9541984732824, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=328, Percent_Identity=26.5243902439024, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=282, Percent_Identity=27.3049645390071, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=329, Percent_Identity=27.9635258358663, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17533517, Length=329, Percent_Identity=25.8358662613982, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=29.4871794871795, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=24.6684350132626, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=313, Percent_Identity=26.1980830670927, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=308, Percent_Identity=26.6233766233766, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=282, Percent_Identity=25.531914893617, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=31.758530183727, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=26.7955801104972, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=27.7777777777778, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=29.0666666666667, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=27.2189349112426, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24660351, Length=319, Percent_Identity=26.9592476489028, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19920834, Length=302, Percent_Identity=27.8145695364238, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 39259; Mature: 39128

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLTEEQTMLRDAAKGWASESAPVGALRKLRDSKSKQTFDPAAWAEMGQMGWAGVIVPE
CCEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECC
AYDGSAFGYLGLGLILEETGRTLAASPLLSTAMIAASALQLGGSDAQKQAWLPKIATGEA
CCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCE
VATLAIDEGAHHAPARTALSATQSGAGYVLNGTKTLVLDGEAADLLIVAARTSGAPGDTN
EEEEEECCCCCCCCHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCC
GITLFLVAGDAAGVTRSHLSLIDSRGAAKIAFDGVEVGADAVLGEVDKGWAVLEPTLDRA
CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHCCHHHHCCCCCCCEEECHHHHHH
YAGLAAEMLGSASAAFDITLDYLKTRTQFGQVIGTFQALQHRAAKWFTDLETTRSCVEAA
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEALDAGADSRALAFLAKAKASELVHLASNEMVQMHGGIGMTDAHDAGLYMKRARVTEAL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
FGGASFHRDRYARLMGF
HCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AVLTEEQTMLRDAAKGWASESAPVGALRKLRDSKSKQTFDPAAWAEMGQMGWAGVIVPE
CEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECC
AYDGSAFGYLGLGLILEETGRTLAASPLLSTAMIAASALQLGGSDAQKQAWLPKIATGEA
CCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCE
VATLAIDEGAHHAPARTALSATQSGAGYVLNGTKTLVLDGEAADLLIVAARTSGAPGDTN
EEEEEECCCCCCCCHHHHHHHCCCCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCC
GITLFLVAGDAAGVTRSHLSLIDSRGAAKIAFDGVEVGADAVLGEVDKGWAVLEPTLDRA
CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHCCHHHHCCCCCCCEEECHHHHHH
YAGLAAEMLGSASAAFDITLDYLKTRTQFGQVIGTFQALQHRAAKWFTDLETTRSCVEAA
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEALDAGADSRALAFLAKAKASELVHLASNEMVQMHGGIGMTDAHDAGLYMKRARVTEAL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
FGGASFHRDRYARLMGF
HCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]