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The map label for this gene is lhr [C]

Identifier: 16126283

GI number: 16126283

Start: 2245333

End: 2247912

Strand: Direct

Name: lhr [C]

Synonym: CC_2040

Alternate gene names: 16126283

Gene position: 2245333-2247912 (Clockwise)

Preceding gene: 16126278

Following gene: 16126284

Centisome position: 55.9

GC content: 68.64

Gene sequence:

>2580_bases
ATGCTCGCGGCGAACGCCCTTCCTCCTCAGTTCCAGGCCTGGTTCGCCAAACGCGGGTGGACCCCGCGCGACCATCAACT
GGCGATGCTGGACAAGGCGCGGGCCGGTCGCGGGGCCTTGCTGATCGCCCCGACGGGCGGTGGCAAGACCCTGGCGGGCT
TCCTGCCCAGCCTGATCGAACTGGCCGAGCGTCCCCCGCGCAATACCCCTGCCGGCGTCCATACCCTCTACATCTCGCCG
CTGAAGGCGCTGGCAGTGGACGTCGAGCGCAACCTGCTGACCCCCATTCGCGAGATGGGCCTGCCGATCGTCGCCGAGAG
CCGCACCGGCGACACCGGCGAGAGCCGCAAGGCCCGCCAGAAGGTCCGCCCGCCCGACATTCTGCTGACCACGCCCGAGC
AACTGGCGCTGTTCTGCGCCTGGGAGGGCGCGCGCGAGTATTTTTCCGACCTGCGCTGCGTGATCATCGATGAGGCCCAT
GCGATCTGGCCCAGCAAGCGCGGCGACCTCCTGGCGCTGGGTCTGTCACGCCTGCAGCAGTTCGCGCCCAACATGCGTCG
GGTCGGATTGTCGGCGACGGTCGATGACCCGGATCTGGTGCGAAAGTGGCTGGGCGTGAACCGGGTGGAAAATCCTCCCC
CGCGCGCGGGGGAGGTGTCGGCGGAGCCGACGGAGGGGGCCAGCACGGCCGACCTCCAGCTCGCCCTCTCCGGCCCTCCG
GGCCACCTCCCCCGCGCGCAGGGGAGGATATGCGAACCCGACATCGACCTCGTCCTGGGCGCCGGCGGCGCGCAGCCGGT
CGTCGAGGTCCTCGTGTCCGGCGGCCGCGTACCCTGGGCCGGTCACACGGCCGAACACGCGATGGCCGAGGTCTATGACA
TCATCAAAGCGGCCAAAACGGCGCTGGTATTCGTCAACACGCGTTTCCAGGCCGAGTTCGCCTTCCAGCGACTGTGGGAG
CTGAACGACGAGGGCCTGCCCATAGCGCTGCACCATGGCAGCCTGTCGGCCGAGCAACGGCGCAAGGTCGAGGCGGCGAT
GGCGCGTGGCGAACTGCGCGCGGTGGTCTGCACCTCGACGCTCGACATGGGCATCGACTGGGGCGACGTGGATCTCGTCA
TCCAGCTGGCCGCGCCCAAGGGGGCCTCGCGGATGGTGCAGCGGATCGGTCGCGCCAACCACCGCCTGGACGAGCCCAGC
CGCGCGATCTTCGTGCCCGCCAGCCGCTTCGAGATGCTCGAGTGCCGCGCCGCCGCCGACGCCATCCTGGAGAACCATCT
GGACGGCGAACCGCCACGCACCGGTGCGCTGGACGTCCTGGCCCAGCACATCATGGGCTGCGCGTGTTCGGAGCCGTTCA
AGCCGACCGACCTCTATGACGAGGTCCGCTCGGCGGGGCCTTACGCCGAGCTGACCTGGGAGGATTTCGAGGCCGTGGTC
GACTTCGTCTCGACCGGCGGCTATGCGCTTCGCACCTACGACAAGTTTCGGCGGATCGTGCAGATCGCCGACGGCCTCAG
GACCGCGCGAAACGCCCAGGCCCGCCAGCAGCACCGCATGAATGTCGGCGCGATCATCTCTCCGGCCATGATCAACATCC
GCATCGGCGGAGGCCGAAAGCCAGTTGGCGGGCGCAAGATCGGCGAGGCCGAGGAAGGCTATTTCGAGCAGCTGACGCCC
GGAGACACCTTCGTCTTCGCCGGTCAGGTCTGGCGATACAACAGCCTCGTCGGGGCCGACGCCTATGTCTCGCCCGCGCC
GAACGACGATCCCAAGATGCCCAGCTGGGGCGGCTCGAAGTTTCCCTTGTCGACCTACCTCGCAGAGCGGGTCCGGCAGA
TGATGCATGACGAGCGCGAGTGGAGCGCCCTGCCCGGCGACGTGCAGGAGTGGCTGTCCTGGCAGAAGATCCGTTCGGCC
ATTCCGGCGGAGGGCGAGATGCTGCTGGAGACCTTCCCGCGCGGGAAGCGGTTCCACATGGTCTGCTATCCGTTCGACGG
GCGCCTTGCCCACACCACCCTGGCCATGCTGCTGACCCGCCGCTTGGACCGTCTGGGCGTCGGCCCGCTGGGCTTTGTCT
GCAACGACTACGCGCTGAACCTGTGGTCGCTGCGCCCCATGGACGATCTCGATCTCGACGAACTGTTCGCCCAGGACATG
CTGGGCGACGACCTTGAGGCTTGGCTGGACGAGAGCTTCATGATGAAGCGGTCGTTCAAGCACTGCGCCCTGATCGCGGG
TCTGATCGAGCGCCGCCACCCTGGCGCCGAGAAGTCCGGCCGGCAGGTGACCTTCTCGACGGACCTGATCTACGACGTGC
TGCGCAAACACCAACCCGACCACCTGATGCTCCGCTGCGCGCGGCTCGACGCGGCCACCGGCCTGCTGGACATCGCGCGC
CTGGGCGACATGCTGACCCGCGTCAGGGGGCGCATCCGGCACGTGGCGCTGGATCGGGTCTCGCCCTTCGCCGTCCCGAT
GATGCTGGAAATCGGCCGCGAGCGCGCGCCCGGCGACGCCGCCGGTGAGATGATCCTGGCCGAGGCTGAAGCCGACCTGA
TCGCCGAGGCGCGGCCGTGA

Upstream 100 bases:

>100_bases
AAGCCAGACAACCGCAAGCTATGGCCGATGCAACCGAACTCGCGCAGGGCGCGCGCAAAAGCAGGGTGAAACAGAAAGGG
AACATGCTATATCGCCAGCA

Downstream 100 bases:

>100_bases
CGCGTTTCCAATCCTCACCCTGCGGCGGCCTTCGCGTTGCGCTCGCCAATGTCGAGGTGATGCTGAGATGGTCCGGCGCA
CTGTGGCTGGAGCGCGAGCG

Product: DEAD-box ATP dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 859

Protein sequence:

>859_residues
MLAANALPPQFQAWFAKRGWTPRDHQLAMLDKARAGRGALLIAPTGGGKTLAGFLPSLIELAERPPRNTPAGVHTLYISP
LKALAVDVERNLLTPIREMGLPIVAESRTGDTGESRKARQKVRPPDILLTTPEQLALFCAWEGAREYFSDLRCVIIDEAH
AIWPSKRGDLLALGLSRLQQFAPNMRRVGLSATVDDPDLVRKWLGVNRVENPPPRAGEVSAEPTEGASTADLQLALSGPP
GHLPRAQGRICEPDIDLVLGAGGAQPVVEVLVSGGRVPWAGHTAEHAMAEVYDIIKAAKTALVFVNTRFQAEFAFQRLWE
LNDEGLPIALHHGSLSAEQRRKVEAAMARGELRAVVCTSTLDMGIDWGDVDLVIQLAAPKGASRMVQRIGRANHRLDEPS
RAIFVPASRFEMLECRAAADAILENHLDGEPPRTGALDVLAQHIMGCACSEPFKPTDLYDEVRSAGPYAELTWEDFEAVV
DFVSTGGYALRTYDKFRRIVQIADGLRTARNAQARQQHRMNVGAIISPAMINIRIGGGRKPVGGRKIGEAEEGYFEQLTP
GDTFVFAGQVWRYNSLVGADAYVSPAPNDDPKMPSWGGSKFPLSTYLAERVRQMMHDEREWSALPGDVQEWLSWQKIRSA
IPAEGEMLLETFPRGKRFHMVCYPFDGRLAHTTLAMLLTRRLDRLGVGPLGFVCNDYALNLWSLRPMDDLDLDELFAQDM
LGDDLEAWLDESFMMKRSFKHCALIAGLIERRHPGAEKSGRQVTFSTDLIYDVLRKHQPDHLMLRCARLDAATGLLDIAR
LGDMLTRVRGRIRHVALDRVSPFAVPMMLEIGRERAPGDAAGEMILAEAEADLIAEARP

Sequences:

>Translated_859_residues
MLAANALPPQFQAWFAKRGWTPRDHQLAMLDKARAGRGALLIAPTGGGKTLAGFLPSLIELAERPPRNTPAGVHTLYISP
LKALAVDVERNLLTPIREMGLPIVAESRTGDTGESRKARQKVRPPDILLTTPEQLALFCAWEGAREYFSDLRCVIIDEAH
AIWPSKRGDLLALGLSRLQQFAPNMRRVGLSATVDDPDLVRKWLGVNRVENPPPRAGEVSAEPTEGASTADLQLALSGPP
GHLPRAQGRICEPDIDLVLGAGGAQPVVEVLVSGGRVPWAGHTAEHAMAEVYDIIKAAKTALVFVNTRFQAEFAFQRLWE
LNDEGLPIALHHGSLSAEQRRKVEAAMARGELRAVVCTSTLDMGIDWGDVDLVIQLAAPKGASRMVQRIGRANHRLDEPS
RAIFVPASRFEMLECRAAADAILENHLDGEPPRTGALDVLAQHIMGCACSEPFKPTDLYDEVRSAGPYAELTWEDFEAVV
DFVSTGGYALRTYDKFRRIVQIADGLRTARNAQARQQHRMNVGAIISPAMINIRIGGGRKPVGGRKIGEAEEGYFEQLTP
GDTFVFAGQVWRYNSLVGADAYVSPAPNDDPKMPSWGGSKFPLSTYLAERVRQMMHDEREWSALPGDVQEWLSWQKIRSA
IPAEGEMLLETFPRGKRFHMVCYPFDGRLAHTTLAMLLTRRLDRLGVGPLGFVCNDYALNLWSLRPMDDLDLDELFAQDM
LGDDLEAWLDESFMMKRSFKHCALIAGLIERRHPGAEKSGRQVTFSTDLIYDVLRKHQPDHLMLRCARLDAATGLLDIAR
LGDMLTRVRGRIRHVALDRVSPFAVPMMLEIGRERAPGDAAGEMILAEAEADLIAEARP
>Mature_859_residues
MLAANALPPQFQAWFAKRGWTPRDHQLAMLDKARAGRGALLIAPTGGGKTLAGFLPSLIELAERPPRNTPAGVHTLYISP
LKALAVDVERNLLTPIREMGLPIVAESRTGDTGESRKARQKVRPPDILLTTPEQLALFCAWEGAREYFSDLRCVIIDEAH
AIWPSKRGDLLALGLSRLQQFAPNMRRVGLSATVDDPDLVRKWLGVNRVENPPPRAGEVSAEPTEGASTADLQLALSGPP
GHLPRAQGRICEPDIDLVLGAGGAQPVVEVLVSGGRVPWAGHTAEHAMAEVYDIIKAAKTALVFVNTRFQAEFAFQRLWE
LNDEGLPIALHHGSLSAEQRRKVEAAMARGELRAVVCTSTLDMGIDWGDVDLVIQLAAPKGASRMVQRIGRANHRLDEPS
RAIFVPASRFEMLECRAAADAILENHLDGEPPRTGALDVLAQHIMGCACSEPFKPTDLYDEVRSAGPYAELTWEDFEAVV
DFVSTGGYALRTYDKFRRIVQIADGLRTARNAQARQQHRMNVGAIISPAMINIRIGGGRKPVGGRKIGEAEEGYFEQLTP
GDTFVFAGQVWRYNSLVGADAYVSPAPNDDPKMPSWGGSKFPLSTYLAERVRQMMHDEREWSALPGDVQEWLSWQKIRSA
IPAEGEMLLETFPRGKRFHMVCYPFDGRLAHTTLAMLLTRRLDRLGVGPLGFVCNDYALNLWSLRPMDDLDLDELFAQDM
LGDDLEAWLDESFMMKRSFKHCALIAGLIERRHPGAEKSGRQVTFSTDLIYDVLRKHQPDHLMLRCARLDAATGLLDIAR
LGDMLTRVRGRIRHVALDRVSPFAVPMMLEIGRERAPGDAAGEMILAEAEADLIAEARP

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=904, Percent_Identity=27.4336283185841, Blast_Score=252, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI17537519, Length=528, Percent_Identity=23.2954545454545, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI9755332, Length=208, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24647182, Length=360, Percent_Identity=25, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 94795; Mature: 94795

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAANALPPQFQAWFAKRGWTPRDHQLAMLDKARAGRGALLIAPTGGGKTLAGFLPSLIE
CCCCCCCCHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
LAERPPRNTPAGVHTLYISPLKALAVDVERNLLTPIREMGLPIVAESRTGDTGESRKARQ
HHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHH
KVRPPDILLTTPEQLALFCAWEGAREYFSDLRCVIIDEAHAIWPSKRGDLLALGLSRLQQ
HCCCCCEEEECHHHHEEEEEHHHHHHHHCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHH
FAPNMRRVGLSATVDDPDLVRKWLGVNRVENPPPRAGEVSAEPTEGASTADLQLALSGPP
HCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
GHLPRAQGRICEPDIDLVLGAGGAQPVVEVLVSGGRVPWAGHTAEHAMAEVYDIIKAAKT
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALVFVNTRFQAEFAFQRLWELNDEGLPIALHHGSLSAEQRRKVEAAMARGELRAVVCTST
EEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECH
LDMGIDWGDVDLVIQLAAPKGASRMVQRIGRANHRLDEPSRAIFVPASRFEMLECRAAAD
HHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHH
AILENHLDGEPPRTGALDVLAQHIMGCACSEPFKPTDLYDEVRSAGPYAELTWEDFEAVV
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEECHHHHHHHH
DFVSTGGYALRTYDKFRRIVQIADGLRTARNAQARQQHRMNVGAIISPAMINIRIGGGRK
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEEECCCCC
PVGGRKIGEAEEGYFEQLTPGDTFVFAGQVWRYNSLVGADAYVSPAPNDDPKMPSWGGSK
CCCCCCCCCCCCCHHHHCCCCCEEEEECCEEEECCEECCCCEECCCCCCCCCCCCCCCCC
FPLSTYLAERVRQMMHDEREWSALPGDVQEWLSWQKIRSAIPAEGEMLLETFPRGKRFHM
CCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEE
VCYPFDGRLAHTTLAMLLTRRLDRLGVGPLGFVCNDYALNLWSLRPMDDLDLDELFAQDM
EEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHEEEEECCCCCCCCHHHHHHHHH
LGDDLEAWLDESFMMKRSFKHCALIAGLIERRHPGAEKSGRQVTFSTDLIYDVLRKHQPD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHCCCC
HLMLRCARLDAATGLLDIARLGDMLTRVRGRIRHVALDRVSPFAVPMMLEIGRERAPGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCH
AGEMILAEAEADLIAEARP
HCCEEEEECCHHHHCCCCC
>Mature Secondary Structure
MLAANALPPQFQAWFAKRGWTPRDHQLAMLDKARAGRGALLIAPTGGGKTLAGFLPSLIE
CCCCCCCCHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
LAERPPRNTPAGVHTLYISPLKALAVDVERNLLTPIREMGLPIVAESRTGDTGESRKARQ
HHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHH
KVRPPDILLTTPEQLALFCAWEGAREYFSDLRCVIIDEAHAIWPSKRGDLLALGLSRLQQ
HCCCCCEEEECHHHHEEEEEHHHHHHHHCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHH
FAPNMRRVGLSATVDDPDLVRKWLGVNRVENPPPRAGEVSAEPTEGASTADLQLALSGPP
HCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
GHLPRAQGRICEPDIDLVLGAGGAQPVVEVLVSGGRVPWAGHTAEHAMAEVYDIIKAAKT
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALVFVNTRFQAEFAFQRLWELNDEGLPIALHHGSLSAEQRRKVEAAMARGELRAVVCTST
EEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECH
LDMGIDWGDVDLVIQLAAPKGASRMVQRIGRANHRLDEPSRAIFVPASRFEMLECRAAAD
HHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHH
AILENHLDGEPPRTGALDVLAQHIMGCACSEPFKPTDLYDEVRSAGPYAELTWEDFEAVV
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEECHHHHHHHH
DFVSTGGYALRTYDKFRRIVQIADGLRTARNAQARQQHRMNVGAIISPAMINIRIGGGRK
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEEECCCCC
PVGGRKIGEAEEGYFEQLTPGDTFVFAGQVWRYNSLVGADAYVSPAPNDDPKMPSWGGSK
CCCCCCCCCCCCCHHHHCCCCCEEEEECCEEEECCEECCCCEECCCCCCCCCCCCCCCCC
FPLSTYLAERVRQMMHDEREWSALPGDVQEWLSWQKIRSAIPAEGEMLLETFPRGKRFHM
CCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEE
VCYPFDGRLAHTTLAMLLTRRLDRLGVGPLGFVCNDYALNLWSLRPMDDLDLDELFAQDM
EEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHEEEEECCCCCCCCHHHHHHHHH
LGDDLEAWLDESFMMKRSFKHCALIAGLIERRHPGAEKSGRQVTFSTDLIYDVLRKHQPD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHCCCC
HLMLRCARLDAATGLLDIARLGDMLTRVRGRIRHVALDRVSPFAVPMMLEIGRERAPGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCH
AGEMILAEAEADLIAEARP
HCCEEEEECCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]