Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 16126141

GI number: 16126141

Start: 2093899

End: 2094924

Strand: Direct

Name: trpD

Synonym: CC_1898

Alternate gene names: 16126141

Gene position: 2093899-2094924 (Clockwise)

Preceding gene: 16126140

Following gene: 16126142

Centisome position: 52.13

GC content: 70.57

Gene sequence:

>1026_bases
ATGTCCGACGCCTTCAAGCCTCTGCTGGCGAAACTCGCCGATGGCCAGACCCTCGACGACAGCGACGCCGAGCTGTTCTT
CGCCGCCTGCCTGCGCGGCGAGCCGACCCCGGCCCAGGTGGCGGCCGCCGTCACCGCGATCCGCCTGCGCGGCGAGACGG
TGGGCGAGATCGCCGCCTGCGCCCGCGCCATGCGTCGCGCCGCCATTCCGCTCGAGCATCCCTACGACGTCATCGACGTC
TGCGGCACCGGCGGCGATGGTCTCCATACGCTGAACATCTCCACCGCCGTCGGCTTTGTGGCCGCAGGCGGCGGCCTGAA
GGTCGCCAAGCACGGCAACCGCGCCATCACGTCCAAGTCCGGCACCGCCGACGTTCTGACCGCGCTCGGCGTCAATATTG
ACGCCACGCGCGAGCAGCAGCGCAAGGCGCTGGACGAGGCCGGCATCTGCTTCCTGTTCGCCCAGGCCCACCATGGCGCG
ATGAAGCATGTCTCGCCGATCCGCCAGCAGCTTGGTTTCCGCACGATCTTCAACCTGCTGGGCCCGTTGACCAATCCGGC
CGGCGCCAAGCGTCAGGTGGTCGGCGTCTCGGCGCCGCGCTTTGTCGAGCCGATCGCCAAGGCCCTGGGGGCTCTTGGGG
CCGAGCGCGCCTGGTCGGTGCATGGCTCGGGCATGGACGAGTTGACGACCACCGGCGAGACCGAAGTGGCCGAATGGCGC
GACGGCGTCGTTCGCCTGTTCAAGATCACCCCCGAAGCCGTTGGCCTGCCGCGCGCCGCGCTAGCGGACCTGACCGGCGG
CGATCCCGCCTTCAACGCCGCGGCCCTGACGCGCCTGTTCGACGGCGAGACCGGCCCCTACCGCGACATCGTGCTGCTCA
ACGCCGCCGCCGCCTTCCTAGTCGCCGACAAGGTCGAGACCCTGGTCGAGGGCGTGGCTCTGGCGGCCGAAGCCATCGAC
AGCGGCCGCGCCAAGGCCGCCCTCGCCGGCCTCGTGGCCGCCACCAACACGGAAGTTCCTGCGTGA

Upstream 100 bases:

>100_bases
CCGAGTCGATCGCCACCGAGGGCGGTCACCAGATGCTGGCCAACTTCATGGATCTGGCCGGCGTCAAGCGCGACGCGGCG
ATCTGGGTCTAGGCACTGCG

Downstream 100 bases:

>100_bases
CCGACATCCTGGCCAAGATCGCCGCCTACAAGCGTGAGGACGTGGCGGCGCGAAAAGCCGAGCGGTCTCAAGCCGAGATC
GACGCCGCCGCCAAGGCCGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSDAFKPLLAKLADGQTLDDSDAELFFAACLRGEPTPAQVAAAVTAIRLRGETVGEIAACARAMRRAAIPLEHPYDVIDV
CGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAITSKSGTADVLTALGVNIDATREQQRKALDEAGICFLFAQAHHGA
MKHVSPIRQQLGFRTIFNLLGPLTNPAGAKRQVVGVSAPRFVEPIAKALGALGAERAWSVHGSGMDELTTTGETEVAEWR
DGVVRLFKITPEAVGLPRAALADLTGGDPAFNAAALTRLFDGETGPYRDIVLLNAAAAFLVADKVETLVEGVALAAEAID
SGRAKAALAGLVAATNTEVPA

Sequences:

>Translated_341_residues
MSDAFKPLLAKLADGQTLDDSDAELFFAACLRGEPTPAQVAAAVTAIRLRGETVGEIAACARAMRRAAIPLEHPYDVIDV
CGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAITSKSGTADVLTALGVNIDATREQQRKALDEAGICFLFAQAHHGA
MKHVSPIRQQLGFRTIFNLLGPLTNPAGAKRQVVGVSAPRFVEPIAKALGALGAERAWSVHGSGMDELTTTGETEVAEWR
DGVVRLFKITPEAVGLPRAALADLTGGDPAFNAAALTRLFDGETGPYRDIVLLNAAAAFLVADKVETLVEGVALAAEAID
SGRAKAALAGLVAATNTEVPA
>Mature_340_residues
SDAFKPLLAKLADGQTLDDSDAELFFAACLRGEPTPAQVAAAVTAIRLRGETVGEIAACARAMRRAAIPLEHPYDVIDVC
GTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAITSKSGTADVLTALGVNIDATREQQRKALDEAGICFLFAQAHHGAM
KHVSPIRQQLGFRTIFNLLGPLTNPAGAKRQVVGVSAPRFVEPIAKALGALGAERAWSVHGSGMDELTTTGETEVAEWRD
GVVRLFKITPEAVGLPRAALADLTGGDPAFNAAALTRLFDGETGPYRDIVLLNAAAAFLVADKVETLVEGVALAAEAIDS
GRAKAALAGLVAATNTEVPA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=46.643109540636, Blast_Score=250, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6320561, Length=371, Percent_Identity=30.188679245283, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_CAUCN (B8GWP8)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002517348.1
- ProteinModelPortal:   B8GWP8
- SMR:   B8GWP8
- GeneID:   7330115
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01975
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35218; Mature: 35086

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAFKPLLAKLADGQTLDDSDAELFFAACLRGEPTPAQVAAAVTAIRLRGETVGEIAAC
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
ARAMRRAAIPLEHPYDVIDVCGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAITSKS
HHHHHHHCCCCCCCCCHHEECCCCCCCEEEEEHHHHHHHHCCCCCEEEEECCCEEEECCC
GTADVLTALGVNIDATREQQRKALDEAGICFLFAQAHHGAMKHVSPIRQQLGFRTIFNLL
CHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHH
GPLTNPAGAKRQVVGVSAPRFVEPIAKALGALGAERAWSVHGSGMDELTTTGETEVAEWR
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCHHHHHH
DGVVRLFKITPEAVGLPRAALADLTGGDPAFNAAALTRLFDGETGPYRDIVLLNAAAAFL
HHHEEEEEECHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHEEEHHHHHHHH
VADKVETLVEGVALAAEAIDSGRAKAALAGLVAATNTEVPA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDAFKPLLAKLADGQTLDDSDAELFFAACLRGEPTPAQVAAAVTAIRLRGETVGEIAAC
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
ARAMRRAAIPLEHPYDVIDVCGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAITSKS
HHHHHHHCCCCCCCCCHHEECCCCCCCEEEEEHHHHHHHHCCCCCEEEEECCCEEEECCC
GTADVLTALGVNIDATREQQRKALDEAGICFLFAQAHHGAMKHVSPIRQQLGFRTIFNLL
CHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHH
GPLTNPAGAKRQVVGVSAPRFVEPIAKALGALGAERAWSVHGSGMDELTTTGETEVAEWR
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCHHHHHH
DGVVRLFKITPEAVGLPRAALADLTGGDPAFNAAALTRLFDGETGPYRDIVLLNAAAAFL
HHHEEEEEECHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHEEEHHHHHHHH
VADKVETLVEGVALAAEAIDSGRAKAALAGLVAATNTEVPA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA