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The map label for this gene is paaG [H]

Identifier: 16126094

GI number: 16126094

Start: 2047842

End: 2048645

Strand: Direct

Name: paaG [H]

Synonym: CC_1851

Alternate gene names: 16126094

Gene position: 2047842-2048645 (Clockwise)

Preceding gene: 16126093

Following gene: 16126098

Centisome position: 50.98

GC content: 69.28

Gene sequence:

>804_bases
GTGGACTATCAGAAGATCCGTGTCTCGACGCAGGATGGCGTCGCCACCGTCACCCTCGCCGATCCGACCACGCTGAACGC
GGCCAGCCCGGAGGTCGCGCGCGAACTGCATCATGCCTTCTCGTCGATCGCCGCCGGCAAGATCGAGGCGCGCGCCGTGA
TCCTCACCGGTGAAGGTCGTGGCTTTTGCTCGGGCGCCAACCTGTCGGGCGGCGGCGCCGCCGGTCGCGAGGCGGACGTC
GACGGCAAGCCCGACGCCGGCTCGGCGCTGGAAACCGTCTACAATCCGCTGATGACCCTGCTGCGAGACTTTCCGCTGCC
GATCGTCACGGCGGTGAACGGTCCGGCCGCCGGGGTGGGCTGCTCGATCGCGCTGATGGGCGACCTGATCGTCGCCGCCG
AGAGCGCCTATTTCCTGCAGGCGTTCCGCCGCATCGGCCTGGTGCCCGACGGCGGCTCGACCTATCTGCTGCCACGCCTG
ATCGGCAAGGCGCGGGCCATGGAGATGATGCTGCTGGGCGACAAGATCCCGGCCGCCACGGCCCTCCAGTGGGGCCTGGT
GAACCGCTGCGTGCCGGACGCCGAGCTGATGGTCACGGCCCACGCCCTGGCGCTGGAACTGGCCAAGGGGCCGGCCGCGC
TGGGCGTCATTCGCAAGCTGGTCTGGGACAGCCTCGACAGCGACTGGACCGGCCAGTTGCACGCCGAGCGCAAGGCCCAG
AAGATCGCCGGCAAGACCGAGGATTTCATCGAAGGCGTCACCGCCTTCCTTCAGAAGCGCGCGGCGGTGTTCAAGGGGCG
GTAG

Upstream 100 bases:

>100_bases
TCCCTGATCGGCGGCGTTTCTGTTTCTGAAGATTTCGCTAGCCTTCCCAAGGGGCAAAGGCGCCTAGACTCGCCCCCAAC
GAACACAGGGAGGCTCCGCC

Downstream 100 bases:

>100_bases
CGGCTTTCGCCTGCAGCGCCAGGAGGATCCCCACCGCCTCCTTCGCCCGCTCGACAGGCACAAAGACATGGTCGTGGTGT
AGCGCCGCGACCATGTTGCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MDYQKIRVSTQDGVATVTLADPTTLNAASPEVARELHHAFSSIAAGKIEARAVILTGEGRGFCSGANLSGGGAAGREADV
DGKPDAGSALETVYNPLMTLLRDFPLPIVTAVNGPAAGVGCSIALMGDLIVAAESAYFLQAFRRIGLVPDGGSTYLLPRL
IGKARAMEMMLLGDKIPAATALQWGLVNRCVPDAELMVTAHALALELAKGPAALGVIRKLVWDSLDSDWTGQLHAERKAQ
KIAGKTEDFIEGVTAFLQKRAAVFKGR

Sequences:

>Translated_267_residues
MDYQKIRVSTQDGVATVTLADPTTLNAASPEVARELHHAFSSIAAGKIEARAVILTGEGRGFCSGANLSGGGAAGREADV
DGKPDAGSALETVYNPLMTLLRDFPLPIVTAVNGPAAGVGCSIALMGDLIVAAESAYFLQAFRRIGLVPDGGSTYLLPRL
IGKARAMEMMLLGDKIPAATALQWGLVNRCVPDAELMVTAHALALELAKGPAALGVIRKLVWDSLDSDWTGQLHAERKAQ
KIAGKTEDFIEGVTAFLQKRAAVFKGR
>Mature_267_residues
MDYQKIRVSTQDGVATVTLADPTTLNAASPEVARELHHAFSSIAAGKIEARAVILTGEGRGFCSGANLSGGGAAGREADV
DGKPDAGSALETVYNPLMTLLRDFPLPIVTAVNGPAAGVGCSIALMGDLIVAAESAYFLQAFRRIGLVPDGGSTYLLPRL
IGKARAMEMMLLGDKIPAATALQWGLVNRCVPDAELMVTAHALALELAKGPAALGVIRKLVWDSLDSDWTGQLHAERKAQ
KIAGKTEDFIEGVTAFLQKRAAVFKGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI221307494, Length=188, Percent_Identity=35.6382978723404, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI194097323, Length=262, Percent_Identity=32.0610687022901, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI221136756, Length=188, Percent_Identity=35.6382978723404, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI221136753, Length=188, Percent_Identity=35.6382978723404, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4757968, Length=188, Percent_Identity=34.5744680851064, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI49355787, Length=188, Percent_Identity=34.5744680851064, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI25453481, Length=224, Percent_Identity=31.6964285714286, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI51538573, Length=224, Percent_Identity=31.6964285714286, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI45643119, Length=270, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI260275230, Length=270, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI4757966, Length=188, Percent_Identity=33.5106382978723, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI51538581, Length=188, Percent_Identity=33.5106382978723, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI260274832, Length=270, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI116235487, Length=188, Percent_Identity=31.9148936170213, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=27.2373540856031, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI70995211, Length=265, Percent_Identity=27.9245283018868, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4502327, Length=250, Percent_Identity=28.4, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=41.3127413127413, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1787659, Length=261, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI221142681, Length=275, Percent_Identity=30.1818181818182, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788597, Length=272, Percent_Identity=30.8823529411765, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082183, Length=279, Percent_Identity=27.2401433691756, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788682, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=256, Percent_Identity=30.46875, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535521, Length=225, Percent_Identity=27.1111111111111, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=29.3436293436293, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=236, Percent_Identity=28.3898305084746, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=262, Percent_Identity=27.4809160305344, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=202, Percent_Identity=31.1881188118812, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=226, Percent_Identity=26.9911504424779, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129971, Length=268, Percent_Identity=30.5970149253731, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24653477, Length=268, Percent_Identity=30.5970149253731, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24654903, Length=194, Percent_Identity=27.319587628866, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI19920382, Length=253, Percent_Identity=28.8537549407115, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=25.9541984732824, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357171, Length=225, Percent_Identity=32, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922422, Length=269, Percent_Identity=23.4200743494424, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27996; Mature: 27996

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYQKIRVSTQDGVATVTLADPTTLNAASPEVARELHHAFSSIAAGKIEARAVILTGEGR
CCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
GFCSGANLSGGGAAGREADVDGKPDAGSALETVYNPLMTLLRDFPLPIVTAVNGPAAGVG
CEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
CSIALMGDLIVAAESAYFLQAFRRIGLVPDGGSTYLLPRLIGKARAMEMMLLGDKIPAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
ALQWGLVNRCVPDAELMVTAHALALELAKGPAALGVIRKLVWDSLDSDWTGQLHAERKAQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KIAGKTEDFIEGVTAFLQKRAAVFKGR
HHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYQKIRVSTQDGVATVTLADPTTLNAASPEVARELHHAFSSIAAGKIEARAVILTGEGR
CCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
GFCSGANLSGGGAAGREADVDGKPDAGSALETVYNPLMTLLRDFPLPIVTAVNGPAAGVG
CEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
CSIALMGDLIVAAESAYFLQAFRRIGLVPDGGSTYLLPRLIGKARAMEMMLLGDKIPAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
ALQWGLVNRCVPDAELMVTAHALALELAKGPAALGVIRKLVWDSLDSDWTGQLHAERKAQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KIAGKTEDFIEGVTAFLQKRAAVFKGR
HHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]