| Definition | Caulobacter crescentus CB15 chromosome, complete genome. |
|---|---|
| Accession | NC_002696 |
| Length | 4,016,947 |
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The map label for this gene is pleD [H]
Identifier: 16126085
GI number: 16126085
Start: 2035367
End: 2036692
Strand: Direct
Name: pleD [H]
Synonym: CC_1842
Alternate gene names: 16126085
Gene position: 2035367-2036692 (Clockwise)
Preceding gene: 16126082
Following gene: 16126086
Centisome position: 50.67
GC content: 70.89
Gene sequence:
>1326_bases TTGGCGGTTGACGCCCGAATCCTGATCGTGGCGCGTGATGATGTTCGCGCCGGACCGCTGGCCGAAGGGCTGGACCGGCT GGGCTGGCGCACCATCACCGCGCGGGGCCCCTATGCCGCGCTCGCCGCCCTGGGCGATCTGCCGATCGAGGCCGTGATCG TCGACATGGCCAGCGCCGGCCCGGAAACCCAGACCCTGGCGCGCCGGCTGAAAGCTGCGGTGGCGCCCCGGCGGTTGCCC GTGATCGCCATCAGCGAGCCGAACGCCGATTTCCGCAGCCAGTCCTTCGATCTGACGCTGTCCCCGCCCCTGCACCCCTC GCAGGCCGCGCTGCGTCTGGAGTCGCTGGTGCGCACGGCCATCGCCGAGGAGGAGTTCGAGCTGCGCCTCGAGACCTTCG GCGAACGCGGTCGCAGGCTGGATCTGCCCGAGCCCTTGGACGCGCCGTATCGCATCCTGGCGGTCGGCGAGCCCGCCCCG CAGTTCCTGGCCCTCTCCAACGCCCTGCAAGCCAGCGGCGCAGAGGTCGTCGGCGCCTTCACGGCCTATACGGCCTTTGA CTATCTGCACGAGCGGCCGTTCGACTCGGTGGTGCTGTGGGCCGGCGACAGTCAGCAGGAAGCGCTGTCGATCGCCGCCG GCATGCGGCGCAACACCCGCCTCTTCCACATTCCGGCGCTGCTCTACCTGAAGGCCGAAAGCTATGTGACGATGTCGGAG GCGTTCCATCGGGGGGTGTCCGACGTCGCCTCGCCGGAAACGCCCGAGGGCGAGACGGCCATGCGGGTCATGGAGCTGGC GCGAAGCTTCCGTCGCGGCGAGTCTATTCGCGGCGCTCTGGAAAAGGCGCGCAGTTCGGGCCTGATGGACGCCGCCACAG GGCTCTTCACCCGTGATCTGTTCGCCGCCCATCTGGCGCGGCTGGCCAGCGCCGCCCGCGAACGGTCGCGGCCCCTGTCG ATCTGCGTTCTGCGCGTCGCCGACAAGCCCGAGACCGTCTGGGCCCGCCAGAACGGCTGGCTGGACCGCGCCATTCCACA GATCGGTTCGATGGTGGGGCGCTTGGTGCGGGTCGAGGATACGCCGGCGCGTCTGGCGACCGAGGTCTTCGCCCTGGCCC TCCCCGCCACCAACCAGAACGCCGCCTGCGCCGCCGCCGAACGGATCGCCGCCGTCATCGGCTGCACCGCCTTCGACGCC GGCGAGGACCGCGCGCCGTTCGTCTGCGAATTCGATATCGGCGTAGCCGAGGTCCAGCCGGGCGAAGGCGCGGTGAAGGC GCTCGAACGGGCCGCCGCCGCCGCGCTGAAGCGCGAGGCGGGCTGA
Upstream 100 bases:
>100_bases TTGCGTGGCTTTGACGACGCGAACCCTCTGCTATGGTGCGGCGTCGAATCCCGCAGGCCCCGACAGGGTCAGCGTCGTAT GTGTTCGGGCGGAGGTTGGT
Downstream 100 bases:
>100_bases CGCTTGTCGCTTGGGGCGCAAGGTCACGCGCCCTATATGGAACACGTCCTGTAGCGGACGATGTTTCCGAGGGAGTTCGC CATGAGCCAGCCGCAAGCCA
Product: response regulator
Products: NA
Alternate protein names: Stalked cell differentiation-controlling protein; Diguanylate cyclase; DGC; Diguanylate kinase [H]
Number of amino acids: Translated: 441; Mature: 440
Protein sequence:
>441_residues MAVDARILIVARDDVRAGPLAEGLDRLGWRTITARGPYAALAALGDLPIEAVIVDMASAGPETQTLARRLKAAVAPRRLP VIAISEPNADFRSQSFDLTLSPPLHPSQAALRLESLVRTAIAEEEFELRLETFGERGRRLDLPEPLDAPYRILAVGEPAP QFLALSNALQASGAEVVGAFTAYTAFDYLHERPFDSVVLWAGDSQQEALSIAAGMRRNTRLFHIPALLYLKAESYVTMSE AFHRGVSDVASPETPEGETAMRVMELARSFRRGESIRGALEKARSSGLMDAATGLFTRDLFAAHLARLASAARERSRPLS ICVLRVADKPETVWARQNGWLDRAIPQIGSMVGRLVRVEDTPARLATEVFALALPATNQNAACAAAERIAAVIGCTAFDA GEDRAPFVCEFDIGVAEVQPGEGAVKALERAAAAALKREAG
Sequences:
>Translated_441_residues MAVDARILIVARDDVRAGPLAEGLDRLGWRTITARGPYAALAALGDLPIEAVIVDMASAGPETQTLARRLKAAVAPRRLP VIAISEPNADFRSQSFDLTLSPPLHPSQAALRLESLVRTAIAEEEFELRLETFGERGRRLDLPEPLDAPYRILAVGEPAP QFLALSNALQASGAEVVGAFTAYTAFDYLHERPFDSVVLWAGDSQQEALSIAAGMRRNTRLFHIPALLYLKAESYVTMSE AFHRGVSDVASPETPEGETAMRVMELARSFRRGESIRGALEKARSSGLMDAATGLFTRDLFAAHLARLASAARERSRPLS ICVLRVADKPETVWARQNGWLDRAIPQIGSMVGRLVRVEDTPARLATEVFALALPATNQNAACAAAERIAAVIGCTAFDA GEDRAPFVCEFDIGVAEVQPGEGAVKALERAAAAALKREAG >Mature_440_residues AVDARILIVARDDVRAGPLAEGLDRLGWRTITARGPYAALAALGDLPIEAVIVDMASAGPETQTLARRLKAAVAPRRLPV IAISEPNADFRSQSFDLTLSPPLHPSQAALRLESLVRTAIAEEEFELRLETFGERGRRLDLPEPLDAPYRILAVGEPAPQ FLALSNALQASGAEVVGAFTAYTAFDYLHERPFDSVVLWAGDSQQEALSIAAGMRRNTRLFHIPALLYLKAESYVTMSEA FHRGVSDVASPETPEGETAMRVMELARSFRRGESIRGALEKARSSGLMDAATGLFTRDLFAAHLARLASAARERSRPLSI CVLRVADKPETVWARQNGWLDRAIPQIGSMVGRLVRVEDTPARLATEVFALALPATNQNAACAAAERIAAVIGCTAFDAG EDRAPFVCEFDIGVAEVQPGEGAVKALERAAAAALKREAG
Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger [H]
COG id: COG3706
COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain
Gene ontology:
Cell location: Cytoplasm. Note=Phosphorylated PleD localizes to the differentiating pole [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 2 response regulatory domains [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001054 - InterPro: IPR011006 - InterPro: IPR000160 - InterPro: IPR001789 [H]
Pfam domain/function: PF00990 GGDEF; PF00072 Response_reg [H]
EC number: =2.7.7.65 [H]
Molecular weight: Translated: 47443; Mature: 47311
Theoretical pI: Translated: 5.40; Mature: 5.40
Prosite motif: PS50110 RESPONSE_REGULATORY
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAVDARILIVARDDVRAGPLAEGLDRLGWRTITARGPYAALAALGDLPIEAVIVDMASAG CCCCEEEEEEECCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHCCCCHHHHEEEHHCCC PETQTLARRLKAAVAPRRLPVIAISEPNADFRSQSFDLTLSPPLHPSQAALRLESLVRTA CHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHH IAEEEFELRLETFGERGRRLDLPEPLDAPYRILAVGEPAPQFLALSNALQASGAEVVGAF HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHH TAYTAFDYLHERPFDSVVLWAGDSQQEALSIAAGMRRNTRLFHIPALLYLKAESYVTMSE HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEECEEEEEECCCCCHHHH AFHRGVSDVASPETPEGETAMRVMELARSFRRGESIRGALEKARSSGLMDAATGLFTRDL HHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH FAAHLARLASAARERSRPLSICVLRVADKPETVWARQNGWLDRAIPQIGSMVGRLVRVED HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHEEEECC TPARLATEVFALALPATNQNAACAAAERIAAVIGCTAFDAGEDRAPFVCEFDIGVAEVQP CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCEEECC GEGAVKALERAAAAALKREAG CCHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure AVDARILIVARDDVRAGPLAEGLDRLGWRTITARGPYAALAALGDLPIEAVIVDMASAG CCCEEEEEEECCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHCCCCHHHHEEEHHCCC PETQTLARRLKAAVAPRRLPVIAISEPNADFRSQSFDLTLSPPLHPSQAALRLESLVRTA CHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHH IAEEEFELRLETFGERGRRLDLPEPLDAPYRILAVGEPAPQFLALSNALQASGAEVVGAF HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHHH TAYTAFDYLHERPFDSVVLWAGDSQQEALSIAAGMRRNTRLFHIPALLYLKAESYVTMSE HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEECEEEEEECCCCCHHHH AFHRGVSDVASPETPEGETAMRVMELARSFRRGESIRGALEKARSSGLMDAATGLFTRDL HHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH FAAHLARLASAARERSRPLSICVLRVADKPETVWARQNGWLDRAIPQIGSMVGRLVRVED HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHEEEECC TPARLATEVFALALPATNQNAACAAAERIAAVIGCTAFDAGEDRAPFVCEFDIGVAEVQP CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCEEECC GEGAVKALERAAAAALKREAG CCHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA