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The map label for this gene is yjjL [H]

Identifier: 16126062

GI number: 16126062

Start: 2011681

End: 2013120

Strand: Direct

Name: yjjL [H]

Synonym: CC_1819

Alternate gene names: 16126062

Gene position: 2011681-2013120 (Clockwise)

Preceding gene: 16126060

Following gene: 16126069

Centisome position: 50.08

GC content: 69.24

Gene sequence:

>1440_bases
TTGCATCCCGGAGGGGTCGCGCCGCGCGCTGGCCCGCGACGCCGCCTAGCGTTCGATCGCAAGACGATCCGCGAGCGGGA
CATGCCAGACCAGAACCTCACCGAACTTGAGCCGCCGCCCGTGGCGTGGTCGGACCGCTATCGGCGCTACGCGCTTGGCC
TGCTGATGCTGATCTATGCGCTCAACATGCTTGACCGCCAGATCATCACCATCCTCGCCGAGCCCATGAAGGCGGAGTTG
AACCTGGCCGATTGGCAGATCGGTGCGGTGAGCGGTCTCGCCTTTGCGCTATTCTACTCCGCCGTCGGCTTGCCGATGGC
GCGCTTCGCGGACCGAGGGGACCGCGTCCGCCTGATCGCCATCTCCCTGGCGGTCTGGAGCGCCTTCACCGCAGTGTGCG
GCCTGGCGCGGACCTTCCCCCAACTCATCCTCGCGCGCATTGGCGTCGGTATCGGCGAAGCCGGTTGCACGCCCGCGGCG
CACTCGCTGATCACCGAATTCACGCCGCGCGCCAAGCTCGCCTCGGCCCTGGCCTTCTACTCGCTGGGCATTCCGCTTGG
CTCGTTGCTGGGCTTAGCGGTCGGGGGGCTGCTCGTCGACGCGATGGGCTGGCGAGCGGCGTTCATCATCGCAGGTCTGC
CCGGCATCGGCGTCGCGGTCATCGCCAGCCTCACCCTTCGTGAGCCTCGGCGCCTGCGCCCCAAGGCCGAGCGCGCGCCC
GGCCAAACGACGTCCCTGGCGGCCGCTCTGGCTGAGCTGAAGCAAAAGCCGGCCTTCTGGCTCATCGCGTTGGCCGCCGC
CCTGACCTCCTTCTCCTACTATGGCCAGTCGGCGTTCTTCGGTTCGGTTTTCCTCCGCAACCACGGTCCGGTGCTTACGC
AGCTTGGCGAGGACCTGGGTCTGGGGCCGGCGGGTCTAGCGGGCCTGGCGCTGGGCCTGGCGATCGGCGTCAGCGCCGGC
GCCGGAACCTTGATCGGCGGCAAACTGGCGGACCGCGCCGCGCGTGGCGGTGTGTCGGGCTACGCCAAGCAGCCGATGGT
GGTCCTGCTCGCGTCGACGCCGTTCCTGGGCGTCACGCCCTTCGCGCCCAACCTCCCGCTCGCCCTCGCCGCGCTCGCCG
TGGGCGTTTTCCTGCACGCCATGGCTTATGGCCCGACCTTCGCCTCGGTGCAGGTGCTGGCGAGTCCCCGTGTCCGCGCG
ACGGCGTCGGCGATCCTGTTCTTCTTGACGAGCCTCATCGGCCTGGGGCTCGGCCCGCTGGCCGTGGGGGTCGCCAGCGA
TCTTCTTCGCGCCAGCCTTGGACCCGTTCAGAGCCTCAACCTCGCCTGCGCAGGCGCTTCGATCACGATGGTCGCGTCCG
TGGTTTGCTTTGGCTTCGCCGCGAGGCAGATGAGCGGCGAAGCGCCGGCTCGGTCTGCTTCAGTGAGCAGCGGCGCCTGA

Upstream 100 bases:

>100_bases
TGGCGCGGCGTCTCCGTCAGCAACTTGGGCAGTCGTCGACGGCGTCGCCGCGTGCTCAAGGCGAAAAGGGCTCGCAGCAC
GGAAGATCACATAGGCGATA

Downstream 100 bases:

>100_bases
ACGGCGCAAAGGCGCCGCACGGACTGCATCGCTTGCAGCAGCGGAGTTTGCAGATTGGGTCCCACGGGCGTTTCCTGCTA
GCGCGTGGCCCAAGGCGTCA

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MHPGGVAPRAGPRRRLAFDRKTIRERDMPDQNLTELEPPPVAWSDRYRRYALGLLMLIYALNMLDRQIITILAEPMKAEL
NLADWQIGAVSGLAFALFYSAVGLPMARFADRGDRVRLIAISLAVWSAFTAVCGLARTFPQLILARIGVGIGEAGCTPAA
HSLITEFTPRAKLASALAFYSLGIPLGSLLGLAVGGLLVDAMGWRAAFIIAGLPGIGVAVIASLTLREPRRLRPKAERAP
GQTTSLAAALAELKQKPAFWLIALAAALTSFSYYGQSAFFGSVFLRNHGPVLTQLGEDLGLGPAGLAGLALGLAIGVSAG
AGTLIGGKLADRAARGGVSGYAKQPMVVLLASTPFLGVTPFAPNLPLALAALAVGVFLHAMAYGPTFASVQVLASPRVRA
TASAILFFLTSLIGLGLGPLAVGVASDLLRASLGPVQSLNLACAGASITMVASVVCFGFAARQMSGEAPARSASVSSGA

Sequences:

>Translated_479_residues
MHPGGVAPRAGPRRRLAFDRKTIRERDMPDQNLTELEPPPVAWSDRYRRYALGLLMLIYALNMLDRQIITILAEPMKAEL
NLADWQIGAVSGLAFALFYSAVGLPMARFADRGDRVRLIAISLAVWSAFTAVCGLARTFPQLILARIGVGIGEAGCTPAA
HSLITEFTPRAKLASALAFYSLGIPLGSLLGLAVGGLLVDAMGWRAAFIIAGLPGIGVAVIASLTLREPRRLRPKAERAP
GQTTSLAAALAELKQKPAFWLIALAAALTSFSYYGQSAFFGSVFLRNHGPVLTQLGEDLGLGPAGLAGLALGLAIGVSAG
AGTLIGGKLADRAARGGVSGYAKQPMVVLLASTPFLGVTPFAPNLPLALAALAVGVFLHAMAYGPTFASVQVLASPRVRA
TASAILFFLTSLIGLGLGPLAVGVASDLLRASLGPVQSLNLACAGASITMVASVVCFGFAARQMSGEAPARSASVSSGA
>Mature_479_residues
MHPGGVAPRAGPRRRLAFDRKTIRERDMPDQNLTELEPPPVAWSDRYRRYALGLLMLIYALNMLDRQIITILAEPMKAEL
NLADWQIGAVSGLAFALFYSAVGLPMARFADRGDRVRLIAISLAVWSAFTAVCGLARTFPQLILARIGVGIGEAGCTPAA
HSLITEFTPRAKLASALAFYSLGIPLGSLLGLAVGGLLVDAMGWRAAFIIAGLPGIGVAVIASLTLREPRRLRPKAERAP
GQTTSLAAALAELKQKPAFWLIALAAALTSFSYYGQSAFFGSVFLRNHGPVLTQLGEDLGLGPAGLAGLALGLAIGVSAG
AGTLIGGKLADRAARGGVSGYAKQPMVVLLASTPFLGVTPFAPNLPLALAALAVGVFLHAMAYGPTFASVQVLASPRVRA
TASAILFFLTSLIGLGLGPLAVGVASDLLRASLGPVQSLNLACAGASITMVASVVCFGFAARQMSGEAPARSASVSSGA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=435, Percent_Identity=26.2068965517241, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI14042968, Length=435, Percent_Identity=26.2068965517241, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367379, Length=426, Percent_Identity=23.2394366197183, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082320, Length=399, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557872, Length=441, Percent_Identity=23.1292517006803, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17539092, Length=405, Percent_Identity=23.9506172839506, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640209, Length=351, Percent_Identity=24.5014245014245, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49535; Mature: 49535

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPGGVAPRAGPRRRLAFDRKTIRERDMPDQNLTELEPPPVAWSDRYRRYALGLLMLIYA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LNMLDRQIITILAEPMKAELNLADWQIGAVSGLAFALFYSAVGLPMARFADRGDRVRLIA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEE
ISLAVWSAFTAVCGLARTFPQLILARIGVGIGEAGCTPAAHSLITEFTPRAKLASALAFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
SLGIPLGSLLGLAVGGLLVDAMGWRAAFIIAGLPGIGVAVIASLTLREPRRLRPKAERAP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCHHHCCC
GQTTSLAAALAELKQKPAFWLIALAAALTSFSYYGQSAFFGSVFLRNHGPVLTQLGEDLG
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCC
LGPAGLAGLALGLAIGVSAGAGTLIGGKLADRAARGGVSGYAKQPMVVLLASTPFLGVTP
CCCHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCC
FAPNLPLALAALAVGVFLHAMAYGPTFASVQVLASPRVRATASAILFFLTSLIGLGLGPL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHH
AVGVASDLLRASLGPVQSLNLACAGASITMVASVVCFGFAARQMSGEAPARSASVSSGA
HHHHHHHHHHHHCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHPGGVAPRAGPRRRLAFDRKTIRERDMPDQNLTELEPPPVAWSDRYRRYALGLLMLIYA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LNMLDRQIITILAEPMKAELNLADWQIGAVSGLAFALFYSAVGLPMARFADRGDRVRLIA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEE
ISLAVWSAFTAVCGLARTFPQLILARIGVGIGEAGCTPAAHSLITEFTPRAKLASALAFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
SLGIPLGSLLGLAVGGLLVDAMGWRAAFIIAGLPGIGVAVIASLTLREPRRLRPKAERAP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCHHHCCC
GQTTSLAAALAELKQKPAFWLIALAAALTSFSYYGQSAFFGSVFLRNHGPVLTQLGEDLG
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCC
LGPAGLAGLALGLAIGVSAGAGTLIGGKLADRAARGGVSGYAKQPMVVLLASTPFLGVTP
CCCHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCC
FAPNLPLALAALAVGVFLHAMAYGPTFASVQVLASPRVRATASAILFFLTSLIGLGLGPL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHH
AVGVASDLLRASLGPVQSLNLACAGASITMVASVVCFGFAARQMSGEAPARSASVSSGA
HHHHHHHHHHHHCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]