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The map label for this gene is yfcX [C]

Identifier: 16126057

GI number: 16126057

Start: 2005179

End: 2006684

Strand: Direct

Name: yfcX [C]

Synonym: CC_1813

Alternate gene names: 16126057

Gene position: 2005179-2006684 (Clockwise)

Preceding gene: 16126055

Following gene: 16126059

Centisome position: 49.92

GC content: 69.65

Gene sequence:

>1506_bases
ATGGGAACGGGAACGACCCGCCGGTCGACGCGCGACGTGCTGACCGGCCAATCCATTCGAACGGTATCAGCGCCCCGGCG
CGGCGTCGCGCAATTGAAACTGGACTGCCCACCGCCCTGCAGCTGGGACGCCGCGCACGCTAGCGCCTTCATCGAGCAAA
TCGCCGCGTTCGGCGATGACCCCGAGGTCTGCGCCATCGTTCTCCACGGTCGCCGCCTGTTCAATGACGTGCTTGCCGCC
AAGACCGCGCCGGATGACTCTCGGTCAGCCGTCTATGCGGCGGTGGCGAGCTCGACCAAGCCGATTGTCGCCGCCCTTTC
GGGCCCTGTCACCGGCTCGGGCCTGGAGCTGGCCCTGGCGTGCGGCGCGCGCGTGGCCTTGCCTAACGTCACCATCTCGA
ACCTGGCCCGCAGCGAAGGCCACCTTCCGGCGGCCGAGACCTTGATCCGCCTGGCCCGACTGGTCGAGGTCGAGCGGGCG
GCCGATCTGGCCGTCTTCAACGCGGTCTGGGACAGCAAGGCGGCGGTCGAGCAAGGCTTGATCGACCTCGTCGCCGCGCG
CGACCTGTTGCAGGTCGCCGAAAAGCTCGCCGCCGGTTGCAAGGAAGAGCGCAGGGTCGCGCTCACGGCGGAACCCGAGG
TCGTGGCCGCCAAGATCTACGGTCTTAGGGCCAAGGTGCGCCGCGAGGCCCCGCAACAGACCGCGCCGATGATGCTGCTG
CGCGCCATGGAGCTCGCCTGGCAGACGCCAGCCCGCCGCGCGCGCGCCGAGATCGATCGCCTGGACGAGACCTTCGCCGC
ATCGCCCGAGGCCCAGGCCTTGACCTATGCCGAGCGTGGCCAGGCCGCCCTGGCCCGCGCCGCCGTTCCCGCCGAACTCG
CGCATGAGCTGGCCTGGCCGCTGCTTCGCGAGGCCATCCACCTGCTGGACGAGGGCGCAACCCCCGGCCAGATCGACCGC
GAACTGCAGAAGTTCGGCTTCCGCGTCGCGCCGTTCCTGCGCTCTGACCGCGAGGGCCTCGAAGCGGTCTTCCGCCGTCA
GTCGGGCCCGGCCAACGGCGAGGACTGGATCACCTATTCGCCGACCCTCGACCTGATGGCCGACGAAGGCCGCACCGGCG
GCGCCGATGCGCCAGGCTGGTACCGCCATGGCAGCGATGGTCGCTACACCTTCGAACCGGAAGTCGATCGGCTGCTACAG
GCCTCGGCCACCTTCCAGCGATGTGCGCGCGCCCCGATCGACGACGAGGTGGTGGTCGAGCGGTGCCTGACTGCAGCGAT
TAACGGCACGGCGCACGTACTTGAAGCGCACCCGGACCTGTCGCCCAGCCTTGTCGACGCCATCTGGACCCAGACCTTGG
GCTTTCCGAAATGGCGCGGCGGACCGCTTTACATGGCCAGGACGGGGGCCTGCGATCCTCTCGCCAGCCTCGAGCGCTGG
ATCAAGGTGCGCAACACGGCCGGCGTCGCCGCCCCGCTGCTGCGTCGGATCATCGCCAACGCCTGA

Upstream 100 bases:

>100_bases
TCGCGTGCTGTTGTTCCGCATGGCGAGCGCTTGGGCGTGCGCCGGACCGGAAAATAACCGCTCGAAAGCGGACCGCGACA
CGCAACCGGTTGGAGGAAAC

Downstream 100 bases:

>100_bases
CGGCTGGCGAAATCTCAAAAAGAAGAGCCAGCGTCACCCGGTGACGCTGGCTTCTTGTTGTCGGAAAGGTCGGCGCGCCG
GCGCCCAGCCAAAGGGCCGA

Product: enoyl-CoA hydratase/isomerase family protein

Products: Trans-2(Or 3)-Enoyl- CoA; H2O. 3-Oxoacyl-CoA; NADH. (R)-3-Hydroxybutanoyl-CoA. [C]

Alternate protein names: Fatty Oxidation Complex Alpha Subunit; Peroxisomal Bifunctional; 3-Hydroxyacyl-CoA Dehydrogenase C-Terminal Domain Family; Enoyl-CoA Hydratase/Isomerase Family Protein; Enoyl-CoA Hydratase/3-Hydroxyacyl-CoA Dehydrogenase; 3-Hydroxybutyryl-CoA Epimerase; Enoyl-CoA Hydratase; 3-Hydroxyacyl-CoA Dehydrogenase Family Protein; Fatty Acid Degradation Protein; 3 2-Trans-Enoyl-CoA Isomerase; Enoyl-CoA Isomerase; Fatty Oxidation Complex Subunit Alpha

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MGTGTTRRSTRDVLTGQSIRTVSAPRRGVAQLKLDCPPPCSWDAAHASAFIEQIAAFGDDPEVCAIVLHGRRLFNDVLAA
KTAPDDSRSAVYAAVASSTKPIVAALSGPVTGSGLELALACGARVALPNVTISNLARSEGHLPAAETLIRLARLVEVERA
ADLAVFNAVWDSKAAVEQGLIDLVAARDLLQVAEKLAAGCKEERRVALTAEPEVVAAKIYGLRAKVRREAPQQTAPMMLL
RAMELAWQTPARRARAEIDRLDETFAASPEAQALTYAERGQAALARAAVPAELAHELAWPLLREAIHLLDEGATPGQIDR
ELQKFGFRVAPFLRSDREGLEAVFRRQSGPANGEDWITYSPTLDLMADEGRTGGADAPGWYRHGSDGRYTFEPEVDRLLQ
ASATFQRCARAPIDDEVVVERCLTAAINGTAHVLEAHPDLSPSLVDAIWTQTLGFPKWRGGPLYMARTGACDPLASLERW
IKVRNTAGVAAPLLRRIIANA

Sequences:

>Translated_501_residues
MGTGTTRRSTRDVLTGQSIRTVSAPRRGVAQLKLDCPPPCSWDAAHASAFIEQIAAFGDDPEVCAIVLHGRRLFNDVLAA
KTAPDDSRSAVYAAVASSTKPIVAALSGPVTGSGLELALACGARVALPNVTISNLARSEGHLPAAETLIRLARLVEVERA
ADLAVFNAVWDSKAAVEQGLIDLVAARDLLQVAEKLAAGCKEERRVALTAEPEVVAAKIYGLRAKVRREAPQQTAPMMLL
RAMELAWQTPARRARAEIDRLDETFAASPEAQALTYAERGQAALARAAVPAELAHELAWPLLREAIHLLDEGATPGQIDR
ELQKFGFRVAPFLRSDREGLEAVFRRQSGPANGEDWITYSPTLDLMADEGRTGGADAPGWYRHGSDGRYTFEPEVDRLLQ
ASATFQRCARAPIDDEVVVERCLTAAINGTAHVLEAHPDLSPSLVDAIWTQTLGFPKWRGGPLYMARTGACDPLASLERW
IKVRNTAGVAAPLLRRIIANA
>Mature_500_residues
GTGTTRRSTRDVLTGQSIRTVSAPRRGVAQLKLDCPPPCSWDAAHASAFIEQIAAFGDDPEVCAIVLHGRRLFNDVLAAK
TAPDDSRSAVYAAVASSTKPIVAALSGPVTGSGLELALACGARVALPNVTISNLARSEGHLPAAETLIRLARLVEVERAA
DLAVFNAVWDSKAAVEQGLIDLVAARDLLQVAEKLAAGCKEERRVALTAEPEVVAAKIYGLRAKVRREAPQQTAPMMLLR
AMELAWQTPARRARAEIDRLDETFAASPEAQALTYAERGQAALARAAVPAELAHELAWPLLREAIHLLDEGATPGQIDRE
LQKFGFRVAPFLRSDREGLEAVFRRQSGPANGEDWITYSPTLDLMADEGRTGGADAPGWYRHGSDGRYTFEPEVDRLLQA
SATFQRCARAPIDDEVVVERCLTAAINGTAHVLEAHPDLSPSLVDAIWTQTLGFPKWRGGPLYMARTGACDPLASLERWI
KVRNTAGVAAPLLRRIIANA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI68989263, Length=198, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI261878539, Length=198, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.17; 1.1.1.35; 5.1.2.3 [C]

Molecular weight: Translated: 53970; Mature: 53839

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTGTTRRSTRDVLTGQSIRTVSAPRRGVAQLKLDCPPPCSWDAAHASAFIEQIAAFGDD
CCCCCCCCHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
PEVCAIVLHGRRLFNDVLAAKTAPDDSRSAVYAAVASSTKPIVAALSGPVTGSGLELALA
HHHEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHH
CGARVALPNVTISNLARSEGHLPAAETLIRLARLVEVERAADLAVFNAVWDSKAAVEQGL
CCCEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IDLVAARDLLQVAEKLAAGCKEERRVALTAEPEVVAAKIYGLRAKVRREAPQQTAPMMLL
HHHHHHHHHHHHHHHHHHCCCHHCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RAMELAWQTPARRARAEIDRLDETFAASPEAQALTYAERGQAALARAAVPAELAHELAWP
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHCCHHHHHHHHHH
LLREAIHLLDEGATPGQIDRELQKFGFRVAPFLRSDREGLEAVFRRQSGPANGEDWITYS
HHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEC
PTLDLMADEGRTGGADAPGWYRHGSDGRYTFEPEVDRLLQASATFQRCARAPIDDEVVVE
CCEEEEECCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RCLTAAINGTAHVLEAHPDLSPSLVDAIWTQTLGFPKWRGGPLYMARTGACDPLASLERW
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHH
IKVRNTAGVAAPLLRRIIANA
HHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
GTGTTRRSTRDVLTGQSIRTVSAPRRGVAQLKLDCPPPCSWDAAHASAFIEQIAAFGDD
CCCCCCCHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
PEVCAIVLHGRRLFNDVLAAKTAPDDSRSAVYAAVASSTKPIVAALSGPVTGSGLELALA
HHHEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHH
CGARVALPNVTISNLARSEGHLPAAETLIRLARLVEVERAADLAVFNAVWDSKAAVEQGL
CCCEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IDLVAARDLLQVAEKLAAGCKEERRVALTAEPEVVAAKIYGLRAKVRREAPQQTAPMMLL
HHHHHHHHHHHHHHHHHHCCCHHCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
RAMELAWQTPARRARAEIDRLDETFAASPEAQALTYAERGQAALARAAVPAELAHELAWP
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHCCHHHHHHHHHH
LLREAIHLLDEGATPGQIDRELQKFGFRVAPFLRSDREGLEAVFRRQSGPANGEDWITYS
HHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEC
PTLDLMADEGRTGGADAPGWYRHGSDGRYTFEPEVDRLLQASATFQRCARAPIDDEVVVE
CCEEEEECCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RCLTAAINGTAHVLEAHPDLSPSLVDAIWTQTLGFPKWRGGPLYMARTGACDPLASLERW
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHH
IKVRNTAGVAAPLLRRIIANA
HHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3s)-3-Hydroxyacyl-CoA L-3-Hydroxyacyl-CoA; NAD(+) (S)-3-Hydroxybutanoyl-CoA [C]

Specific reaction: (3s)-3-Hydroxyacyl-CoA = Trans-2(Or 3)-Enoyl- CoA + H2O. L-3-Hydroxyacyl-CoA + NAD(+) = 3-Oxoacyl-CoA + NADH. (S)-3-Hydroxybutanoyl-CoA = (R)-3-Hydroxybutanoyl-CoA. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA