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The map label for this gene is foxA [H]

Identifier: 16126022

GI number: 16126022

Start: 1961452

End: 1963650

Strand: Direct

Name: foxA [H]

Synonym: CC_1778

Alternate gene names: 16126022

Gene position: 1961452-1963650 (Clockwise)

Preceding gene: 16126021

Following gene: 16126023

Centisome position: 48.83

GC content: 65.98

Gene sequence:

>2199_bases
GTGGCAGGTCGTGAACTGGAACAAGGCCAACGCCCTGTTCGACGCCGCCGCGCGCTAGGCGCGCACCTCACAAGAAAAAA
CCTTCTCTCAAAGCCGCCCGGGGGCGCTAAGGACACGATGAAAACAGCACTCTTTCTCGGTAGCGCCATCGCGGTGATCG
GTGCGCCGTCGCTTGTTCTGGCGCAGGCCTCGCCCTCTAGCTGGGTCAGCGAGGTCGTGATCACCAGCCCGAAGGGCAGC
TTCACCGCGCCCAGCGCGCTGAGCGCCACGCGAACCGCGACCCCGGTCGAGGAAATCCCGCAATCGATCCAGACCCTGAC
GCGAGGGCTGATCGAGGACCAGGCGCTGCAGACCCTGTCAGGCGCGCTGGTCAACGTCTCGGGCGTCACCCCGACCAGCA
CCGAACAGTCCGTGCTGCAGCCACCGCTGATCCGCGGCTTCCCGGTCAGCTACTATTTCGACGGCGCGCCGACCTACCAG
CTGCCTGCGGGCATCGCCGACCCCGCCACCCTGGTCAATGTCGAGCGGATCGAAGTGGCCAAGGGCCCGACCAGCACGCT
CTATGGCGGCGGTTCGGGCGCCCCGCTCTCGGGGATCATCAACGTCGTCTCCCAGGATCCAGGCGAGACCTTCGGCGGGA
CGGTCGCCCTGCGCGCCGGCAGCTTCAACACCCTGGGGGCCGACGCGGCGATCAATCTGCCGGTCAATGACAAGGTCGGG
CTGCGTCTGGCCGGCATGACCGAGAAGGCCGACAGCTATATCGACCACATCGATAGCCGCCGCTACGCGATCTTCCCGAC
CCTGGCCGTCGAGATGAGTGACAAGACGCGCCTGGTCGTTCGCGGCCGCTACAACCACCTCGAACAGCGCGAATATGCCG
GCGTGCCGGCGGGGCTGACCTTCGCGCCGTCCCTGGTCATTGATCGCTACAAGTTCGCGGGCGCGCTGGACGCCCCCCGC
ACCCGCATCACCAACAAGCAGCTGACCGCCAACCTGACGCACAAGATCTCTGACAAGGTCGAGGCCAGCGTCACGGCCAG
CCGCTATGAGGGCGCGTTCAAGGAATGGTCGTCCTTCCCCTATGGCCAGATCTCTGGCTCGGTCTACAACTTCGGCACGG
CCTATCTGCCCTCGGACACGACCGAGACCTACGCAACGGGCAGCCTGACCGCGCGTCTGGGTGAAGGCCTTGTCCGCCAC
CAGGTACTGGTCGGCGTCGACTATGACAAGACGCGCTACTTCGGCGCGATGTACTTCAACCCGGCCTGGGCGACGCTGGA
CTACGCCGCCGCCCGTCCGTACGCCGCCTTTGGCGGCAATCCGCCGTTCTTCTTCGACCAGAACGACCGCATGCGCACGA
CGGCGGTCTTCGTCCAAGACCAGATCGCCATTGGCGAGCGTCTCGACATCACGGCCGGCCTGCGTTGGACGACACTGAAG
ATCCAAAGCAATGTCGGCGCTGCGACGGCCGACACCGACAAGCGCGTCACGCCGCGTATCGGCGCCACCTATCGGATCGC
CAACGGCGTCTCGGCCTTCGCCGGCTACGCCGAGGGCTTCAAGGGCGTGGTCGCGGGAGGCTTCTACGGCATCACCCCCA
AGCCGGAAACGTCCCAGTCCTATGAAGGCGGCCTGAAGTTCGCGGCCCCGATCAAGGGGCTCACCGGCACGGTCTCGTTC
TACCAGATCACCCGTCAGAACGTGATCACCGCGCACCCGACGATCCCGTTCGTCTCGGTGCAGACGGGCGAGCAGCGCTC
GAAGGGCGTCGAAACCGATCTGGTCTACGAGCCGTCCCCGGCCCTCTCGGTGCTGTTCAACTACGCGTATACCAAAGCGA
AGATCAGCAAGGACAACACCTTGCCAGTCGGCGACCGTCTGCGTGCTGTTCCTGAACATTCGGGCCGCCTGGCCGCCAAC
TACCGCTTCCTGGCCGGCGACCTGAAGGGCCTGCGGATCGGCGGCGGCCTGACCGCCACGTCCAGCCGCGAACTGACCCT
GCCCAACACCGTCGCCGCCAAGGGCCTGGCCCTGATCGACGCCCAGGCCTCGTACGACCTGGGCGTGGTCCGGATCGGGC
TGTCGGTGGTCAATCTGGCCGGCCGCAAGGGCTTCGAGCCCTATCAGTACTTCGGCGGCCCCTATGTGATCCCGACCCAG
CCCCGTTCGGCGTTCGTCAGCCTGCGAACGATTTTCTAA

Upstream 100 bases:

>100_bases
ACGCGCCGGTCAAGGGCGCGCCGATCCTGGCCAATGATGTCTGGGAACACGCCTACTACCTGAAACACCAGAACAACCGC
GGCGCCTATCTCGGCGGCTG

Downstream 100 bases:

>100_bases
GGCCACGAAGCCAGGGAGGCCAAACCATGAGAATGTTTCAATCGCCCTTGTGGCGCGGCCTCCTTGGATCGCTCGCTGCG
GTCATGGTGCTGGGGATGGC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MAGRELEQGQRPVRRRRALGAHLTRKNLLSKPPGGAKDTMKTALFLGSAIAVIGAPSLVLAQASPSSWVSEVVITSPKGS
FTAPSALSATRTATPVEEIPQSIQTLTRGLIEDQALQTLSGALVNVSGVTPTSTEQSVLQPPLIRGFPVSYYFDGAPTYQ
LPAGIADPATLVNVERIEVAKGPTSTLYGGGSGAPLSGIINVVSQDPGETFGGTVALRAGSFNTLGADAAINLPVNDKVG
LRLAGMTEKADSYIDHIDSRRYAIFPTLAVEMSDKTRLVVRGRYNHLEQREYAGVPAGLTFAPSLVIDRYKFAGALDAPR
TRITNKQLTANLTHKISDKVEASVTASRYEGAFKEWSSFPYGQISGSVYNFGTAYLPSDTTETYATGSLTARLGEGLVRH
QVLVGVDYDKTRYFGAMYFNPAWATLDYAAARPYAAFGGNPPFFFDQNDRMRTTAVFVQDQIAIGERLDITAGLRWTTLK
IQSNVGAATADTDKRVTPRIGATYRIANGVSAFAGYAEGFKGVVAGGFYGITPKPETSQSYEGGLKFAAPIKGLTGTVSF
YQITRQNVITAHPTIPFVSVQTGEQRSKGVETDLVYEPSPALSVLFNYAYTKAKISKDNTLPVGDRLRAVPEHSGRLAAN
YRFLAGDLKGLRIGGGLTATSSRELTLPNTVAAKGLALIDAQASYDLGVVRIGLSVVNLAGRKGFEPYQYFGGPYVIPTQ
PRSAFVSLRTIF

Sequences:

>Translated_732_residues
MAGRELEQGQRPVRRRRALGAHLTRKNLLSKPPGGAKDTMKTALFLGSAIAVIGAPSLVLAQASPSSWVSEVVITSPKGS
FTAPSALSATRTATPVEEIPQSIQTLTRGLIEDQALQTLSGALVNVSGVTPTSTEQSVLQPPLIRGFPVSYYFDGAPTYQ
LPAGIADPATLVNVERIEVAKGPTSTLYGGGSGAPLSGIINVVSQDPGETFGGTVALRAGSFNTLGADAAINLPVNDKVG
LRLAGMTEKADSYIDHIDSRRYAIFPTLAVEMSDKTRLVVRGRYNHLEQREYAGVPAGLTFAPSLVIDRYKFAGALDAPR
TRITNKQLTANLTHKISDKVEASVTASRYEGAFKEWSSFPYGQISGSVYNFGTAYLPSDTTETYATGSLTARLGEGLVRH
QVLVGVDYDKTRYFGAMYFNPAWATLDYAAARPYAAFGGNPPFFFDQNDRMRTTAVFVQDQIAIGERLDITAGLRWTTLK
IQSNVGAATADTDKRVTPRIGATYRIANGVSAFAGYAEGFKGVVAGGFYGITPKPETSQSYEGGLKFAAPIKGLTGTVSF
YQITRQNVITAHPTIPFVSVQTGEQRSKGVETDLVYEPSPALSVLFNYAYTKAKISKDNTLPVGDRLRAVPEHSGRLAAN
YRFLAGDLKGLRIGGGLTATSSRELTLPNTVAAKGLALIDAQASYDLGVVRIGLSVVNLAGRKGFEPYQYFGGPYVIPTQ
PRSAFVSLRTIF
>Mature_731_residues
AGRELEQGQRPVRRRRALGAHLTRKNLLSKPPGGAKDTMKTALFLGSAIAVIGAPSLVLAQASPSSWVSEVVITSPKGSF
TAPSALSATRTATPVEEIPQSIQTLTRGLIEDQALQTLSGALVNVSGVTPTSTEQSVLQPPLIRGFPVSYYFDGAPTYQL
PAGIADPATLVNVERIEVAKGPTSTLYGGGSGAPLSGIINVVSQDPGETFGGTVALRAGSFNTLGADAAINLPVNDKVGL
RLAGMTEKADSYIDHIDSRRYAIFPTLAVEMSDKTRLVVRGRYNHLEQREYAGVPAGLTFAPSLVIDRYKFAGALDAPRT
RITNKQLTANLTHKISDKVEASVTASRYEGAFKEWSSFPYGQISGSVYNFGTAYLPSDTTETYATGSLTARLGEGLVRHQ
VLVGVDYDKTRYFGAMYFNPAWATLDYAAARPYAAFGGNPPFFFDQNDRMRTTAVFVQDQIAIGERLDITAGLRWTTLKI
QSNVGAATADTDKRVTPRIGATYRIANGVSAFAGYAEGFKGVVAGGFYGITPKPETSQSYEGGLKFAAPIKGLTGTVSFY
QITRQNVITAHPTIPFVSVQTGEQRSKGVETDLVYEPSPALSVLFNYAYTKAKISKDNTLPVGDRLRAVPEHSGRLAANY
RFLAGDLKGLRIGGGLTATSSRELTLPNTVAAKGLALIDAQASYDLGVVRIGLSVVNLAGRKGFEPYQYFGGPYVIPTQP
RSAFVSLRTIF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=695, Percent_Identity=27.0503597122302, Blast_Score=159, Evalue=7e-40,
Organism=Escherichia coli, GI1787344, Length=602, Percent_Identity=24.5847176079734, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787024, Length=273, Percent_Identity=25.2747252747253, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78253; Mature: 78121

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00683 RHODANESE_2 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRELEQGQRPVRRRRALGAHLTRKNLLSKPPGGAKDTMKTALFLGSAIAVIGAPSLVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
AQASPSSWVSEVVITSPKGSFTAPSALSATRTATPVEEIPQSIQTLTRGLIEDQALQTLS
EECCCHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GALVNVSGVTPTSTEQSVLQPPLIRGFPVSYYFDGAPTYQLPAGIADPATLVNVERIEVA
CCEEEECCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCEECCCCCCCCHHEEEEEEEEEC
KGPTSTLYGGGSGAPLSGIINVVSQDPGETFGGTVALRAGSFNTLGADAAINLPVNDKVG
CCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCC
LRLAGMTEKADSYIDHIDSRRYAIFPTLAVEMSDKTRLVVRGRYNHLEQREYAGVPAGLT
EEEECCCHHHHHHHHHHCCCCEEEEEEEEEEECCCEEEEEECCCCCHHHHHHCCCCCCCC
FAPSLVIDRYKFAGALDAPRTRITNKQLTANLTHKISDKVEASVTASRYEGAFKEWSSFP
CCCHHHHHHHHHCCCCCCCCHHCCCCHHEEHHHHHHHHHHHHHEEHHHHCCHHHHHHCCC
YGQISGSVYNFGTAYLPSDTTETYATGSLTARLGEGLVRHQVLVGVDYDKTRYFGAMYFN
CCCCCCCEEECCEEECCCCCCCCEECCCHHHHHHCHHHHEEEEEECCCCCCEEEEEEEEC
PAWATLDYAAARPYAAFGGNPPFFFDQNDRMRTTAVFVQDQIAIGERLDITAGLRWTTLK
CCHHEEEHHHCCCCHHCCCCCCEEECCCCCEEEEEEEEEHHCCCCCEEEEECCCEEEEEE
IQSNVGAATADTDKRVTPRIGATYRIANGVSAFAGYAEGFKGVVAGGFYGITPKPETSQS
EECCCCCEECCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCEEEECCEECCCCCCCCCCC
YEGGLKFAAPIKGLTGTVSFYQITRQNVITAHPTIPFVSVQTGEQRSKGVETDLVYEPSP
CCCCEEEECCCCCCCCCEEEEEEECCCEEEECCCCCEEEEECCCHHHCCCCCEEEECCCH
ALSVLFNYAYTKAKISKDNTLPVGDRLRAVPEHSGRLAANYRFLAGDLKGLRIGGGLTAT
HHHHHHHHHHHEEEECCCCCCCCCHHHHCCCCCCCCEEECEEEEECCCCEEEECCCEEEC
SSRELTLPNTVAAKGLALIDAQASYDLGVVRIGLSVVNLAGRKGFEPYQYFGGPYVIPTQ
CCCCEECCCHHHHCCEEEEECCCCCCCEEEEEHHHHHHHCCCCCCCCHHHCCCCEEEECC
PRSAFVSLRTIF
CHHHEEEEEECC
>Mature Secondary Structure 
AGRELEQGQRPVRRRRALGAHLTRKNLLSKPPGGAKDTMKTALFLGSAIAVIGAPSLVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
AQASPSSWVSEVVITSPKGSFTAPSALSATRTATPVEEIPQSIQTLTRGLIEDQALQTLS
EECCCHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GALVNVSGVTPTSTEQSVLQPPLIRGFPVSYYFDGAPTYQLPAGIADPATLVNVERIEVA
CCEEEECCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCEECCCCCCCCHHEEEEEEEEEC
KGPTSTLYGGGSGAPLSGIINVVSQDPGETFGGTVALRAGSFNTLGADAAINLPVNDKVG
CCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCC
LRLAGMTEKADSYIDHIDSRRYAIFPTLAVEMSDKTRLVVRGRYNHLEQREYAGVPAGLT
EEEECCCHHHHHHHHHHCCCCEEEEEEEEEEECCCEEEEEECCCCCHHHHHHCCCCCCCC
FAPSLVIDRYKFAGALDAPRTRITNKQLTANLTHKISDKVEASVTASRYEGAFKEWSSFP
CCCHHHHHHHHHCCCCCCCCHHCCCCHHEEHHHHHHHHHHHHHEEHHHHCCHHHHHHCCC
YGQISGSVYNFGTAYLPSDTTETYATGSLTARLGEGLVRHQVLVGVDYDKTRYFGAMYFN
CCCCCCCEEECCEEECCCCCCCCEECCCHHHHHHCHHHHEEEEEECCCCCCEEEEEEEEC
PAWATLDYAAARPYAAFGGNPPFFFDQNDRMRTTAVFVQDQIAIGERLDITAGLRWTTLK
CCHHEEEHHHCCCCHHCCCCCCEEECCCCCEEEEEEEEEHHCCCCCEEEEECCCEEEEEE
IQSNVGAATADTDKRVTPRIGATYRIANGVSAFAGYAEGFKGVVAGGFYGITPKPETSQS
EECCCCCEECCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCEEEECCEECCCCCCCCCCC
YEGGLKFAAPIKGLTGTVSFYQITRQNVITAHPTIPFVSVQTGEQRSKGVETDLVYEPSP
CCCCEEEECCCCCCCCCEEEEEEECCCEEEECCCCCEEEEECCCHHHCCCCCEEEECCCH
ALSVLFNYAYTKAKISKDNTLPVGDRLRAVPEHSGRLAANYRFLAGDLKGLRIGGGLTAT
HHHHHHHHHHHEEEECCCCCCCCCHHHHCCCCCCCCEEECEEEEECCCCEEEECCCEEEC
SSRELTLPNTVAAKGLALIDAQASYDLGVVRIGLSVVNLAGRKGFEPYQYFGGPYVIPTQ
CCCCEECCCHHHHCCEEEEECCCCCCCEEEEEHHHHHHHCCCCCCCCHHHCCCCEEEECC
PRSAFVSLRTIF
CHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]