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The map label for this gene is betA [C]

Identifier: 16125880

GI number: 16125880

Start: 1811742

End: 1813481

Strand: Direct

Name: betA [C]

Synonym: CC_1634

Alternate gene names: 16125880

Gene position: 1811742-1813481 (Clockwise)

Preceding gene: 16125878

Following gene: 16125881

Centisome position: 45.1

GC content: 65.63

Gene sequence:

>1740_bases
ATGGCCAACCTGAACGGCCGCGCGCGTCGTAAGAACACCTACGACGCCATCGTGGTGGGCAGTGGCATTACCGGTGGCAT
CGCGGCCAAGGAATTGACCGAAAAGGGGTTGAAGGTCCTTGTGCTCGAGCGGGGACCCATGGTGCGCCACCTTGAGGACT
ATCCCACGGCGATGTTGGACCCGTGGCAGTCAAAATATCCGCAGGGTAAGCTCCCCGAGGCCGAGCTGAACGCGCACTAC
AAGGTGCAGCGGCGCACCGGCTACACGATGACGGAGCAAACCCAGCACTTCTTCGTGCGGGACGACGAGCACCCCTACAC
CGAGGAGAACCGCTTCGACTGGATCCGGGGCTATCATGTCGGCGGCCGCTCGCTGACCTGGGGGCGGCAGAGCTATCGCC
ACAGCCCGATCGATTTCGAGGCAAACGCTCGCGAAGGAATCGCGGTCGACTGGCCGATCCGCTACGAGGATCTCGCGCCC
TGGTACGAGCATGTCGAGCGCTTCATCGGAGTTTCCGGACAGGCCGAGGGCCTGCCGCATTTTCCGGACGGCCACTACCA
GCCGCCGATGGAGCTGAACTGCGTCGAGAAGGCCTTCAAGGCGCGGTCCGAGGCGCGCTTCCCCGAGCGGCGCGTCACGA
TCGGGCGCACGGCCCACCTGACCGATCCCACCGAGGAGCAGCTCGCGCTGGGGCGTACCAAGTGCCAGTACCGCAACCTC
TGTATCCGCGGCTGCCCGTTCGGCGCCTATTACAGCTCCAATTCAGGCGGGCTGATCGCGGCCGAGCGGACGGGAAATCT
GGTGATCCGTCCCAACTCGATCGTCACCGAGCTGATCTATGATGAGCGCGCAGGACGAGCCAGCGGCGTGCGGATTCTGG
ACGCAGAGACCCGAAAGGACGAGGAGTTCCACGCCGATGTGATCTTCCTCTGCGCCTCGGCGCTGAACTCCGCGTGGATC
ATGATGAACTCGACGAGTTCGCGGTTCCCGAACGGCTTCGGCAACGCCAGCGATCAGCTTGGCCGCAACGTTATGGACCA
CCACCTGGGCGCGGGAGCAACGGGCCAGGCGCCGGAATTCGCGGACATGTACTTCTCGGGGCGCCGGCCGAACGGCATCT
ATGTGCCTCGCTTCCGCAATCTTGGTGATGCGGCCAGCAAGCGCTCGGACTATCTGCGGGGCTTCGGCTATCAGGGCGGC
GCCGGGCGCGCGACCTGGGAGCGTGATCGCGGTCAGGGCGGGCGAGGTTTCGGCGCAGCGCGCAAGGCCGCGCTCAGCCA
GCCCGGGCCCTGGACCATGGGGCTTAGCGGGTTCGGCGAGATGCTCCCTTACGCCGACAACCGCGTGACGCTGAACCGCG
ACGTCGAGGACAAGTTCGGCCTGCCGACCCTGACCATGAACGTCACCATGCGCGACAACGAGATGGCGATGCGCCGCGAC
ATGCAGGCGGCCGCCGCCGAGATGCTCGAGGCGGCGGGGTTCCAGAACGTGCGAGCGCATGACAACGGCTTCGCGCCGGG
GCTTGGCATCCATGAGATGGGAACGGCCCGCATGGGGCGTGACCCCAAGACCTCGGTGCTGAACGCGCACAATCAGGTTC
ACGAGTGCAAGAACGTCTATGTCACCGACGGGGCGGCCATGGCTTCGGCCTCGTGCGTCAATCCATCCTTGACCTACATG
GCCCTGACGGCCCGCGCCGCCGACCATGCGGTACGCGCCCGCAAGCGGGGAGAACTGTAA

Upstream 100 bases:

>100_bases
TGGAAGCCTCCAGGCAAGAATGAAGAGGTCGCCGGGGTTTGTGTCGTGTTGCGTGAAGCATCTCGATGCGGTCCATTGAG
CGACTGCGAAGGGAGCGAAC

Downstream 100 bases:

>100_bases
TGCTGAACCGACGCGACGCCCTTCGCGGTCTGGCTCTGACGGTCGGCGCCGCGGCGACGGGATGGGCGGGAACCGCTGCG
GCGACGACGGCGCTGAGCTG

Product: GMC family oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MANLNGRARRKNTYDAIVVGSGITGGIAAKELTEKGLKVLVLERGPMVRHLEDYPTAMLDPWQSKYPQGKLPEAELNAHY
KVQRRTGYTMTEQTQHFFVRDDEHPYTEENRFDWIRGYHVGGRSLTWGRQSYRHSPIDFEANAREGIAVDWPIRYEDLAP
WYEHVERFIGVSGQAEGLPHFPDGHYQPPMELNCVEKAFKARSEARFPERRVTIGRTAHLTDPTEEQLALGRTKCQYRNL
CIRGCPFGAYYSSNSGGLIAAERTGNLVIRPNSIVTELIYDERAGRASGVRILDAETRKDEEFHADVIFLCASALNSAWI
MMNSTSSRFPNGFGNASDQLGRNVMDHHLGAGATGQAPEFADMYFSGRRPNGIYVPRFRNLGDAASKRSDYLRGFGYQGG
AGRATWERDRGQGGRGFGAARKAALSQPGPWTMGLSGFGEMLPYADNRVTLNRDVEDKFGLPTLTMNVTMRDNEMAMRRD
MQAAAAEMLEAAGFQNVRAHDNGFAPGLGIHEMGTARMGRDPKTSVLNAHNQVHECKNVYVTDGAAMASASCVNPSLTYM
ALTARAADHAVRARKRGEL

Sequences:

>Translated_579_residues
MANLNGRARRKNTYDAIVVGSGITGGIAAKELTEKGLKVLVLERGPMVRHLEDYPTAMLDPWQSKYPQGKLPEAELNAHY
KVQRRTGYTMTEQTQHFFVRDDEHPYTEENRFDWIRGYHVGGRSLTWGRQSYRHSPIDFEANAREGIAVDWPIRYEDLAP
WYEHVERFIGVSGQAEGLPHFPDGHYQPPMELNCVEKAFKARSEARFPERRVTIGRTAHLTDPTEEQLALGRTKCQYRNL
CIRGCPFGAYYSSNSGGLIAAERTGNLVIRPNSIVTELIYDERAGRASGVRILDAETRKDEEFHADVIFLCASALNSAWI
MMNSTSSRFPNGFGNASDQLGRNVMDHHLGAGATGQAPEFADMYFSGRRPNGIYVPRFRNLGDAASKRSDYLRGFGYQGG
AGRATWERDRGQGGRGFGAARKAALSQPGPWTMGLSGFGEMLPYADNRVTLNRDVEDKFGLPTLTMNVTMRDNEMAMRRD
MQAAAAEMLEAAGFQNVRAHDNGFAPGLGIHEMGTARMGRDPKTSVLNAHNQVHECKNVYVTDGAAMASASCVNPSLTYM
ALTARAADHAVRARKRGEL
>Mature_578_residues
ANLNGRARRKNTYDAIVVGSGITGGIAAKELTEKGLKVLVLERGPMVRHLEDYPTAMLDPWQSKYPQGKLPEAELNAHYK
VQRRTGYTMTEQTQHFFVRDDEHPYTEENRFDWIRGYHVGGRSLTWGRQSYRHSPIDFEANAREGIAVDWPIRYEDLAPW
YEHVERFIGVSGQAEGLPHFPDGHYQPPMELNCVEKAFKARSEARFPERRVTIGRTAHLTDPTEEQLALGRTKCQYRNLC
IRGCPFGAYYSSNSGGLIAAERTGNLVIRPNSIVTELIYDERAGRASGVRILDAETRKDEEFHADVIFLCASALNSAWIM
MNSTSSRFPNGFGNASDQLGRNVMDHHLGAGATGQAPEFADMYFSGRRPNGIYVPRFRNLGDAASKRSDYLRGFGYQGGA
GRATWERDRGQGGRGFGAARKAALSQPGPWTMGLSGFGEMLPYADNRVTLNRDVEDKFGLPTLTMNVTMRDNEMAMRRDM
QAAAAEMLEAAGFQNVRAHDNGFAPGLGIHEMGTARMGRDPKTSVLNAHNQVHECKNVYVTDGAAMASASCVNPSLTYMA
LTARAADHAVRARKRGEL

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 64398; Mature: 64267

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLNGRARRKNTYDAIVVGSGITGGIAAKELTEKGLKVLVLERGPMVRHLEDYPTAMLD
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHCCHHHCC
PWQSKYPQGKLPEAELNAHYKVQRRTGYTMTEQTQHFFVRDDEHPYTEENRFDWIRGYHV
CHHHCCCCCCCCHHHCCCEEEEEECCCCEECCCCCEEEEECCCCCCCCCCCCCCEEEEEC
GGRSLTWGRQSYRHSPIDFEANAREGIAVDWPIRYEDLAPWYEHVERFIGVSGQAEGLPH
CCCCEECCHHHHCCCCCCCCCCCCCCEEEECCCCHHHCCHHHHHHHHHHCCCCCCCCCCC
FPDGHYQPPMELNCVEKAFKARSEARFPERRVTIGRTAHLTDPTEEQLALGRTKCQYRNL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHCE
CIRGCPFGAYYSSNSGGLIAAERTGNLVIRPNSIVTELIYDERAGRASGVRILDAETRKD
EEECCCCCCEEECCCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCC
EEFHADVIFLCASALNSAWIMMNSTSSRFPNGFGNASDQLGRNVMDHHLGAGATGQAPEF
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCH
ADMYFSGRRPNGIYVPRFRNLGDAASKRSDYLRGFGYQGGAGRATWERDRGQGGRGFGAA
HHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
RKAALSQPGPWTMGLSGFGEMLPYADNRVTLNRDVEDKFGLPTLTMNVTMRDNEMAMRRD
HHHHCCCCCCCEECHHHHHHHCCCCCCEEEECCCCHHHCCCCEEEEEEEECCCHHHHHHH
MQAAAAEMLEAAGFQNVRAHDNGFAPGLGIHEMGTARMGRDPKTSVLNAHNQVHECKNVY
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHCCEE
VTDGAAMASASCVNPSLTYMALTARAADHAVRARKRGEL
EECCHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANLNGRARRKNTYDAIVVGSGITGGIAAKELTEKGLKVLVLERGPMVRHLEDYPTAMLD
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHCCHHHCC
PWQSKYPQGKLPEAELNAHYKVQRRTGYTMTEQTQHFFVRDDEHPYTEENRFDWIRGYHV
CHHHCCCCCCCCHHHCCCEEEEEECCCCEECCCCCEEEEECCCCCCCCCCCCCCEEEEEC
GGRSLTWGRQSYRHSPIDFEANAREGIAVDWPIRYEDLAPWYEHVERFIGVSGQAEGLPH
CCCCEECCHHHHCCCCCCCCCCCCCCEEEECCCCHHHCCHHHHHHHHHHCCCCCCCCCCC
FPDGHYQPPMELNCVEKAFKARSEARFPERRVTIGRTAHLTDPTEEQLALGRTKCQYRNL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHCE
CIRGCPFGAYYSSNSGGLIAAERTGNLVIRPNSIVTELIYDERAGRASGVRILDAETRKD
EEECCCCCCEEECCCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCC
EEFHADVIFLCASALNSAWIMMNSTSSRFPNGFGNASDQLGRNVMDHHLGAGATGQAPEF
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCH
ADMYFSGRRPNGIYVPRFRNLGDAASKRSDYLRGFGYQGGAGRATWERDRGQGGRGFGAA
HHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
RKAALSQPGPWTMGLSGFGEMLPYADNRVTLNRDVEDKFGLPTLTMNVTMRDNEMAMRRD
HHHHCCCCCCCEECHHHHHHHCCCCCCEEEECCCCHHHCCCCEEEEEEEECCCHHHHHHH
MQAAAAEMLEAAGFQNVRAHDNGFAPGLGIHEMGTARMGRDPKTSVLNAHNQVHECKNVY
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHCCEE
VTDGAAMASASCVNPSLTYMALTARAADHAVRARKRGEL
EECCHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]