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The map label for this gene is astB2

Identifier: 16125855

GI number: 16125855

Start: 1781538

End: 1782878

Strand: Direct

Name: astB2

Synonym: CC_1608

Alternate gene names: 16125855

Gene position: 1781538-1782878 (Clockwise)

Preceding gene: 16125854

Following gene: 16125856

Centisome position: 44.35

GC content: 69.05

Gene sequence:

>1341_bases
GTGATCTCAGCGTTCGAGGCGAACTGCGACGGCCTGGTCGGGCCGACGCACTCGTATGTCGGTCTCTCGCCCGGCAATCT
GGCCAGCACGCGCAACGCCGGCGAGGTCTCCAATCCGCGCGGCGCGGCGCTGGAAGGGCTCGCCAAGATGCGCCGGCTGG
CCGATCTGGGGCTGCCGCAGTTCGTACTGCCGCCGCATGAGCGACCGGCCGTAAGCCTCTTGAGGCAGCTGGGTTTTTCC
GGTCCGGATGAGATCGTTCTGACGTCGGCTTGGCGCGATGCGCCGGCCCTGGCCGCCGCCGCCTGTTCAGCCTCGCCGAT
GTGGGCCGCGAACGCCGCGACGGTCACCCCCAGCGCCGACGCCGCCGATGGTCGCGTGCATTTCACGCCCGCCAACCTTC
TGACCAACCTGCATCGCAGCCTGGAGGGCCGTCAGACGGCGCGGTCGCTTCGACGGCTGTTCGCCGATGAGACCCGGTTC
GCCGTCCACGATCCCTTGCCCGCCCAGCCGCATTTCGCCGACGAGGGCGCGGCCAACCATGTGCGCCTCTGCGCCGAGCA
TGGCGGGCCGGGGGTGAACCTGTTCGTCTGGGGACGTGAGGCCTGGAGCCACTGGGACGGCCGGTTCCCCGCCCGCCAGA
CCAAGGAAGCGTTCGAGGCGATCCAACGTCGACACGGTGCGGCACGCGCGGTGTTTCCGCAGCAGGGCAAGGCGGCGATC
GAGGGCGGCGCTTTCCACAATGACGTCGTCTGCGTTGGGACGCGTGAGTGTCTGTTCTTCCACGAGCGAGCCTTCGAGGA
TCGCGCCACGATGGCGCGCGAGGTCCGGGCGGCGGCGAGCGGCCTGTTCGAGCCGGCCTTCGTCGAGGTGACGGAGGCCG
ATCTGCCGATGGCTGATCTGGTGGCCAGCTATCTGTTCAATTCGCAGCTGCTGGTCGTGCCGGGCGAGGACCGGCTGGTG
TTGTTGGCACCCGTCGAGACGCGGGACAATCCCCGCGCCTACGCCGTGGCCGAGAGCCTCGCAACCTCGAACGGCCCCAT
CGGCCGGGTCGAGTACGTCGACGTCCGCCAAAGCATGCGCAATGGCGGCGGGCCCGCCTGCCTGCGCCTCCGCGTCGTGC
TGACCGAGGCTGAGCTGGCGGCGGCAAACCCGGCCCAACGGTTCACTGCCGACCTTCAGGACGCCCTGGCCGACTGGATC
ACGCGCCGCTATCGCGATCGTCTTTCGCCGGCGGATCTGGCCGACGCCAAGCTCCTGACCGAGAGCCGTGAGGCGCTTGA
CGAGCTGACCCAGATCCTGGGATTGGGCGATGACTTCTACCCCTTCCAGAGAACGGCATGA

Upstream 100 bases:

>100_bases
CGAGCGCCTATTACGCCGCAGACTACTGCGCCTATCCTGTCGCGAGTTTCGAGGCTTCAATGGTCGTTGATACCTTGAAG
GATATCAAGGGCTTGAAGGC

Downstream 100 bases:

>100_bases
GCATCACGGTTCGTCGCGCCACGGTCGCCGATCGCGACGCGATCGTTGCTGTGCATCGCTCCGCAGCTGTGACGCCCGGC
GCCTTGGCCCGCACGCCCGA

Product: succinylarginine dihydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MISAFEANCDGLVGPTHSYVGLSPGNLASTRNAGEVSNPRGAALEGLAKMRRLADLGLPQFVLPPHERPAVSLLRQLGFS
GPDEIVLTSAWRDAPALAAAACSASPMWAANAATVTPSADAADGRVHFTPANLLTNLHRSLEGRQTARSLRRLFADETRF
AVHDPLPAQPHFADEGAANHVRLCAEHGGPGVNLFVWGREAWSHWDGRFPARQTKEAFEAIQRRHGAARAVFPQQGKAAI
EGGAFHNDVVCVGTRECLFFHERAFEDRATMAREVRAAASGLFEPAFVEVTEADLPMADLVASYLFNSQLLVVPGEDRLV
LLAPVETRDNPRAYAVAESLATSNGPIGRVEYVDVRQSMRNGGGPACLRLRVVLTEAELAAANPAQRFTADLQDALADWI
TRRYRDRLSPADLADAKLLTESREALDELTQILGLGDDFYPFQRTA

Sequences:

>Translated_446_residues
MISAFEANCDGLVGPTHSYVGLSPGNLASTRNAGEVSNPRGAALEGLAKMRRLADLGLPQFVLPPHERPAVSLLRQLGFS
GPDEIVLTSAWRDAPALAAAACSASPMWAANAATVTPSADAADGRVHFTPANLLTNLHRSLEGRQTARSLRRLFADETRF
AVHDPLPAQPHFADEGAANHVRLCAEHGGPGVNLFVWGREAWSHWDGRFPARQTKEAFEAIQRRHGAARAVFPQQGKAAI
EGGAFHNDVVCVGTRECLFFHERAFEDRATMAREVRAAASGLFEPAFVEVTEADLPMADLVASYLFNSQLLVVPGEDRLV
LLAPVETRDNPRAYAVAESLATSNGPIGRVEYVDVRQSMRNGGGPACLRLRVVLTEAELAAANPAQRFTADLQDALADWI
TRRYRDRLSPADLADAKLLTESREALDELTQILGLGDDFYPFQRTA
>Mature_446_residues
MISAFEANCDGLVGPTHSYVGLSPGNLASTRNAGEVSNPRGAALEGLAKMRRLADLGLPQFVLPPHERPAVSLLRQLGFS
GPDEIVLTSAWRDAPALAAAACSASPMWAANAATVTPSADAADGRVHFTPANLLTNLHRSLEGRQTARSLRRLFADETRF
AVHDPLPAQPHFADEGAANHVRLCAEHGGPGVNLFVWGREAWSHWDGRFPARQTKEAFEAIQRRHGAARAVFPQQGKAAI
EGGAFHNDVVCVGTRECLFFHERAFEDRATMAREVRAAASGLFEPAFVEVTEADLPMADLVASYLFNSQLLVVPGEDRLV
LLAPVETRDNPRAYAVAESLATSNGPIGRVEYVDVRQSMRNGGGPACLRLRVVLTEAELAAANPAQRFTADLQDALADWI
TRRYRDRLSPADLADAKLLTESREALDELTQILGLGDDFYPFQRTA

Specific function: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)

COG id: COG3724

COG function: function code E; Succinylarginine dihydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinylarginine dihydrolase family

Homologues:

Organism=Escherichia coli, GI1788041, Length=446, Percent_Identity=50.2242152466368, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTB2_CAUCR (Q9A7W1)

Other databases:

- EMBL:   AE005673
- PIR:   G87448
- RefSeq:   NP_420419.1
- HSSP:   P76216
- ProteinModelPortal:   Q9A7W1
- SMR:   Q9A7W1
- GeneID:   942472
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_1608
- NMPDR:   fig|190650.1.peg.1599
- TIGR:   CC_1608
- HOGENOM:   HBG289862
- OMA:   HFAHHPA
- ProtClustDB:   PRK13281
- BRENDA:   3.5.3.23
- HAMAP:   MF_01172
- InterPro:   IPR007079
- Gene3D:   G3DSA:3.75.10.20
- TIGRFAMs:   TIGR03241

Pfam domain/function: PF04996 AstB

EC number: =3.5.3.23

Molecular weight: Translated: 48315; Mature: 48315

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: ACT_SITE 175-175 ACT_SITE 246-246 ACT_SITE 367-367 BINDING 111-111 BINDING 212-212 BINDING 248-248 BINDING 361-361

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAFEANCDGLVGPTHSYVGLSPGNLASTRNAGEVSNPRGAALEGLAKMRRLADLGLPQ
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
FVLPPHERPAVSLLRQLGFSGPDEIVLTSAWRDAPALAAAACSASPMWAANAATVTPSAD
CCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEEECCCCC
AADGRVHFTPANLLTNLHRSLEGRQTARSLRRLFADETRFAVHDPLPAQPHFADEGAANH
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCH
VRLCAEHGGPGVNLFVWGREAWSHWDGRFPARQTKEAFEAIQRRHGAARAVFPQQGKAAI
HHHHHHCCCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
EGGAFHNDVVCVGTRECLFFHERAFEDRATMAREVRAAASGLFEPAFVEVTEADLPMADL
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
VASYLFNSQLLVVPGEDRLVLLAPVETRDNPRAYAVAESLATSNGPIGRVEYVDVRQSMR
HHHHHHCCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHH
NGGGPACLRLRVVLTEAELAAANPAQRFTADLQDALADWITRRYRDRLSPADLADAKLLT
CCCCCEEEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ESREALDELTQILGLGDDFYPFQRTA
HHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MISAFEANCDGLVGPTHSYVGLSPGNLASTRNAGEVSNPRGAALEGLAKMRRLADLGLPQ
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
FVLPPHERPAVSLLRQLGFSGPDEIVLTSAWRDAPALAAAACSASPMWAANAATVTPSAD
CCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEEECCCCC
AADGRVHFTPANLLTNLHRSLEGRQTARSLRRLFADETRFAVHDPLPAQPHFADEGAANH
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCH
VRLCAEHGGPGVNLFVWGREAWSHWDGRFPARQTKEAFEAIQRRHGAARAVFPQQGKAAI
HHHHHHCCCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
EGGAFHNDVVCVGTRECLFFHERAFEDRATMAREVRAAASGLFEPAFVEVTEADLPMADL
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
VASYLFNSQLLVVPGEDRLVLLAPVETRDNPRAYAVAESLATSNGPIGRVEYVDVRQSMR
HHHHHHCCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHH
NGGGPACLRLRVVLTEAELAAANPAQRFTADLQDALADWITRRYRDRLSPADLADAKLLT
CCCCCEEEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ESREALDELTQILGLGDDFYPFQRTA
HHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647