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The map label for this gene is cysW [H]

Identifier: 16125844

GI number: 16125844

Start: 1765600

End: 1766457

Strand: Direct

Name: cysW [H]

Synonym: CC_1597

Alternate gene names: 16125844

Gene position: 1765600-1766457 (Clockwise)

Preceding gene: 16125843

Following gene: 16125845

Centisome position: 43.95

GC content: 65.73

Gene sequence:

>858_bases
ATGGGAGCCGCAAGTTCCAAGGCGCGGGGCGCCACCGATGATCCGGCGTGGGCCAAGATCCTGCTCATCGGCGCCGTTTT
TGTCTTTCTGGCCTTGGTGCTGATCCTGCCGCTGGTCGCGGTGTTCGCCGAGGCGCTTCGAAAGGGCCTGGACGCGGCGA
TCTTGGCGGCCCGTCAACCCGACGCTCTGGCGGCGGTGAAGCTGACCTTGCTGACAGCCGCCATCGCCGTCCCGTTCAAC
GCGGTGTTCGGACTTTGCGCAGCCTGGGCGATCGCCAAGCACGATTTCCGCGGCAAGGCCCTGCTGATCACCCTGATTGA
CTTGCCATTTTCGGTCTCGCCGGTGGTCGCGGGCCTGATCTATGTGCTGATCTTTGGCCTGCAGGGCTGGTTTGGCGAGT
GGCTGCTCGACAACGACATCAGGATCATCTTCGCCGTGCCGGGCATCGTGCTGGCGACGGTGTTCGTGACCTTCCCCTTC
GTGGCGCGCGAACTGATCCCGCTGATGCAGGAGCAGGGAACCAGCGAGGAGGAGGCGGCCATCTCGATGGGCGCCAGCGG
GCTCTACACCTTCTGGCGGGTGACCGCGCCCAACGTGCGCTGGGGGCTGCTCTATGGCGTGCTGCTGTGCAACGCCCGCG
CCATGGGCGAGTTCGGCGCGGTCTCGGTGGTCAGCGGTCACATCCGGGGCCTGACCAACACCATGCCGCTGCACGTCGAG
ATCCTCTACAACGAGTACGACTTTGTCGGCGCTTTCGCCGTGGCGGCGCTGCTCTGCCTTCTGGCGGTGGTGACTCTGGT
GCTGAAGACGGCGCTTGAGATCGCTCAGCCGGACGTGCGTGGCCGCCGCGGACACTGA

Upstream 100 bases:

>100_bases
ACACGCGCGCGGCGACGATCGCAGTCGTGATGCTGGCGGTCTCGTTCCTGATGCTGCTGATCATCAACGCCATCCAGGCC
TGGGCGCGGAGGTTCGACTG

Downstream 100 bases:

>100_bases
ACGGACTACGGAACCCATGACCATTGCCATCCGCTCCGTCGAAAAGCAGTTCGGGCGCTATCCGGCCTTGAACAAGGTCG
ATCTGGAGATCGCCGACGGC

Product: sulfate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MGAASSKARGATDDPAWAKILLIGAVFVFLALVLILPLVAVFAEALRKGLDAAILAARQPDALAAVKLTLLTAAIAVPFN
AVFGLCAAWAIAKHDFRGKALLITLIDLPFSVSPVVAGLIYVLIFGLQGWFGEWLLDNDIRIIFAVPGIVLATVFVTFPF
VARELIPLMQEQGTSEEEAAISMGASGLYTFWRVTAPNVRWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHVE
ILYNEYDFVGAFAVAALLCLLAVVTLVLKTALEIAQPDVRGRRGH

Sequences:

>Translated_285_residues
MGAASSKARGATDDPAWAKILLIGAVFVFLALVLILPLVAVFAEALRKGLDAAILAARQPDALAAVKLTLLTAAIAVPFN
AVFGLCAAWAIAKHDFRGKALLITLIDLPFSVSPVVAGLIYVLIFGLQGWFGEWLLDNDIRIIFAVPGIVLATVFVTFPF
VARELIPLMQEQGTSEEEAAISMGASGLYTFWRVTAPNVRWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHVE
ILYNEYDFVGAFAVAALLCLLAVVTLVLKTALEIAQPDVRGRRGH
>Mature_284_residues
GAASSKARGATDDPAWAKILLIGAVFVFLALVLILPLVAVFAEALRKGLDAAILAARQPDALAAVKLTLLTAAIAVPFNA
VFGLCAAWAIAKHDFRGKALLITLIDLPFSVSPVVAGLIYVLIFGLQGWFGEWLLDNDIRIIFAVPGIVLATVFVTFPFV
ARELIPLMQEQGTSEEEAAISMGASGLYTFWRVTAPNVRWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHVEI
LYNEYDFVGAFAVAALLCLLAVVTLVLKTALEIAQPDVRGRRGH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=273, Percent_Identity=50.1831501831502, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1788764, Length=200, Percent_Identity=39, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786980, Length=223, Percent_Identity=32.7354260089686, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787369, Length=150, Percent_Identity=29.3333333333333, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30442; Mature: 30311

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAASSKARGATDDPAWAKILLIGAVFVFLALVLILPLVAVFAEALRKGLDAAILAARQP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
DALAAVKLTLLTAAIAVPFNAVFGLCAAWAIAKHDFRGKALLITLIDLPFSVSPVVAGLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
YVLIFGLQGWFGEWLLDNDIRIIFAVPGIVLATVFVTFPFVARELIPLMQEQGTSEEEAA
HHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ISMGASGLYTFWRVTAPNVRWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHVE
HHCCCCHHHHEEEEECCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCCCEEEE
ILYNEYDFVGAFAVAALLCLLAVVTLVLKTALEIAQPDVRGRRGH
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GAASSKARGATDDPAWAKILLIGAVFVFLALVLILPLVAVFAEALRKGLDAAILAARQP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
DALAAVKLTLLTAAIAVPFNAVFGLCAAWAIAKHDFRGKALLITLIDLPFSVSPVVAGLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
YVLIFGLQGWFGEWLLDNDIRIIFAVPGIVLATVFVTFPFVARELIPLMQEQGTSEEEAA
HHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ISMGASGLYTFWRVTAPNVRWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHVE
HHCCCCHHHHEEEEECCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCCCEEEE
ILYNEYDFVGAFAVAALLCLLAVVTLVLKTALEIAQPDVRGRRGH
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]