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The map label for this gene is qor [H]

Identifier: 16125816

GI number: 16125816

Start: 1735014

End: 1735976

Strand: Direct

Name: qor [H]

Synonym: CC_1569

Alternate gene names: 16125816

Gene position: 1735014-1735976 (Clockwise)

Preceding gene: 16125815

Following gene: 16125817

Centisome position: 43.19

GC content: 67.91

Gene sequence:

>963_bases
ATGAAGGCGGCTGTCTATTATGAAACCGGCGCTCCGGACGTCCTGCGCTATGAGGATGCCGCCGATCCGGTCTGCCACGC
GCAAGGCGTCGTCATCCGCGTCGAGGCCGTCAGCATCGAGGGCGGCGACACGCTCAATCGCGGCGGCGGCCAGATGGCGG
GCGTCCCGCACATTGTCGGCTACCAGGCGGCCGGCGAGATCATCGAAGTCGGCGCCGAGGTCTCGCACCTGAAGGTCGGC
CAGAAGGTCGTGACCGTGAACGCCTTCGGCTCGCATGCCGAACTGCGCTCCGTGCCGGCGCGTAACGCCTGGCCGATCCC
CGAGGGCTTTGATCTCCACAAGGCCGCCGCCATCCCCGTGCCGTTCGGCACGGCGCACGAGTGCCTGTTCGGCGCCGGGC
GCCTGAAGGCCGGCGAAACCGTTCTGGTCCAGGCTGGGGCCGGCGCCGTGGGCCTGGCCGCCATTCAACTGGCCAAGCAG
GCCGGCGCGACGGTTCTGGCCTCGGCCTCCAGCGACGAGCGTCTGGAGCGTCTGAAGCCGTTCGGTATGGATCACGGGAT
CAACTATCGGCGCGATGATCTGGTCGAACAGGTCATGAAGCTGACCGGCGGCAAGGGCGTCGATCTGGTCGTTGACCCCG
TCGGCGGAGCGACTCTGCCTGGCAGTCTGGCGGCTTTGGGCTACCGGGGCCGCGTCTCGCTGGTGGGCAACGCCGGCCGC
GAGCCGATGAAGGTCGATGTCGGCTCACTGATGGGCGGTAATCGCAGCCTGACCGGCGTGTTCCTGGGCGCCGAGATCAT
GACCGATCGCGTCCATGACATGATCCAGGACCTGATCGAGAAGGCGGCGCGCGGCGAGCTTGAGGTCGTCATCGACCGCA
CCTTCCCGCTGTCGCAAGCCGCCGCCGCCCACGCCTATATCGAAAGCCGCCAAGCCGTCGGCCGCGTGCTGCTCATTCCC
TGA

Upstream 100 bases:

>100_bases
AAGGACATCGACGATGACAGCGCCAAGCTCGTCTACGACGCGCTGATCGATCCGAAGAAATAGCGGCCAAAGCTGCAAAC
TGTTCAGGGAGGATCGCCCC

Downstream 100 bases:

>100_bases
GGCCGATCATGACCAACCGCGTGCTTGCCCATACCGGGGCGAAATATCCGATCATCCAGGCCCCGATGGGCTGGATCGCT
CGCTATCAACTGGCCAGCGC

Product: NADP-dependent quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKAAVYYETGAPDVLRYEDAADPVCHAQGVVIRVEAVSIEGGDTLNRGGGQMAGVPHIVGYQAAGEIIEVGAEVSHLKVG
QKVVTVNAFGSHAELRSVPARNAWPIPEGFDLHKAAAIPVPFGTAHECLFGAGRLKAGETVLVQAGAGAVGLAAIQLAKQ
AGATVLASASSDERLERLKPFGMDHGINYRRDDLVEQVMKLTGGKGVDLVVDPVGGATLPGSLAALGYRGRVSLVGNAGR
EPMKVDVGSLMGGNRSLTGVFLGAEIMTDRVHDMIQDLIEKAARGELEVVIDRTFPLSQAAAAHAYIESRQAVGRVLLIP

Sequences:

>Translated_320_residues
MKAAVYYETGAPDVLRYEDAADPVCHAQGVVIRVEAVSIEGGDTLNRGGGQMAGVPHIVGYQAAGEIIEVGAEVSHLKVG
QKVVTVNAFGSHAELRSVPARNAWPIPEGFDLHKAAAIPVPFGTAHECLFGAGRLKAGETVLVQAGAGAVGLAAIQLAKQ
AGATVLASASSDERLERLKPFGMDHGINYRRDDLVEQVMKLTGGKGVDLVVDPVGGATLPGSLAALGYRGRVSLVGNAGR
EPMKVDVGSLMGGNRSLTGVFLGAEIMTDRVHDMIQDLIEKAARGELEVVIDRTFPLSQAAAAHAYIESRQAVGRVLLIP
>Mature_320_residues
MKAAVYYETGAPDVLRYEDAADPVCHAQGVVIRVEAVSIEGGDTLNRGGGQMAGVPHIVGYQAAGEIIEVGAEVSHLKVG
QKVVTVNAFGSHAELRSVPARNAWPIPEGFDLHKAAAIPVPFGTAHECLFGAGRLKAGETVLVQAGAGAVGLAAIQLAKQ
AGATVLASASSDERLERLKPFGMDHGINYRRDDLVEQVMKLTGGKGVDLVVDPVGGATLPGSLAALGYRGRVSLVGNAGR
EPMKVDVGSLMGGNRSLTGVFLGAEIMTDRVHDMIQDLIEKAARGELEVVIDRTFPLSQAAAAHAYIESRQAVGRVLLIP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=30.4878048780488, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=30.4878048780488, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI194239674, Length=324, Percent_Identity=29.9382716049383, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI13236495, Length=324, Percent_Identity=29.9382716049383, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=30, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI194239676, Length=217, Percent_Identity=31.3364055299539, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI28557745, Length=247, Percent_Identity=32.7935222672065, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI24308257, Length=340, Percent_Identity=24.4117647058824, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI41872631, Length=138, Percent_Identity=34.0579710144928, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI197927207, Length=192, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI47519420, Length=360, Percent_Identity=26.3888888888889, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI226059159, Length=135, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI226059133, Length=135, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI226056130, Length=135, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787863, Length=338, Percent_Identity=27.5147928994083, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790045, Length=240, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=313, Percent_Identity=27.7955271565495, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=233, Percent_Identity=30.0429184549356, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=251, Percent_Identity=27.0916334661355, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=320, Percent_Identity=31.25, Blast_Score=125, Evalue=7e-30,
Organism=Drosophila melanogaster, GI221330659, Length=230, Percent_Identity=30.4347826086957, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920632, Length=230, Percent_Identity=30.4347826086957, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24581345, Length=227, Percent_Identity=28.1938325991189, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33367; Mature: 33367

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVYYETGAPDVLRYEDAADPVCHAQGVVIRVEAVSIEGGDTLNRGGGQMAGVPHIVG
CCEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEC
YQAAGEIIEVGAEVSHLKVGQKVVTVNAFGSHAELRSVPARNAWPIPEGFDLHKAAAIPV
HHHHCHHHHHCCCHHEEECCCEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCEEECCC
PFGTAHECLFGAGRLKAGETVLVQAGAGAVGLAAIQLAKQAGATVLASASSDERLERLKP
CCCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCC
FGMDHGINYRRDDLVEQVMKLTGGKGVDLVVDPVGGATLPGSLAALGYRGRVSLVGNAGR
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHCCCCCEEEEEECCCC
EPMKVDVGSLMGGNRSLTGVFLGAEIMTDRVHDMIQDLIEKAARGELEVVIDRTFPLSQA
CCEEEEHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
AAAHAYIESRQAVGRVLLIP
HHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MKAAVYYETGAPDVLRYEDAADPVCHAQGVVIRVEAVSIEGGDTLNRGGGQMAGVPHIVG
CCEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEC
YQAAGEIIEVGAEVSHLKVGQKVVTVNAFGSHAELRSVPARNAWPIPEGFDLHKAAAIPV
HHHHCHHHHHCCCHHEEECCCEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCEEECCC
PFGTAHECLFGAGRLKAGETVLVQAGAGAVGLAAIQLAKQAGATVLASASSDERLERLKP
CCCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCC
FGMDHGINYRRDDLVEQVMKLTGGKGVDLVVDPVGGATLPGSLAALGYRGRVSLVGNAGR
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHCCCCCEEEEEECCCC
EPMKVDVGSLMGGNRSLTGVFLGAEIMTDRVHDMIQDLIEKAARGELEVVIDRTFPLSQA
CCEEEEHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
AAAHAYIESRQAVGRVLLIP
HHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]