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The map label for this gene is era

Identifier: 16125809

GI number: 16125809

Start: 1725609

End: 1726610

Strand: Direct

Name: era

Synonym: CC_1562

Alternate gene names: 16125809

Gene position: 1725609-1726610 (Clockwise)

Preceding gene: 16125808

Following gene: 16125810

Centisome position: 42.96

GC content: 66.67

Gene sequence:

>1002_bases
TTGAAGCCCCTCGCTACCGCCGAACCCCCATCGGTGCTACACGCACGCGTAATGACTGACACCACCTCCAAAACCCGCGC
AGGCTTCGCCGCCATCATCGGCGCGCCGAACGCCGGCAAGTCCACCCTGGTCAACCGCATGGTCGGGGCCAAGGTCTCGA
TCGTGACCCAGAAGGTCCAGACCACCCGCTTCCCCGTGCGCGGCGTCGCCATCGAGGGCGACACTCAGATCGTCCTCGTC
GACACCCCCGGGATCTTCAGCCCCCGCCGGCGTCTGGACCGGGCCATGGTCCGCGCCGCCTGGGCCGGTTCGGAAGAGGC
CGAGGCCACCGTTCACCTCGTCGACGTGCAGGCCGAACTGGCCAGCCGCGCCGACAAGGCTACGCCCGGCGAGTACCGCT
CGGCCCAGGACGTGCAGACCATCATCGAGGGCCTGAAGGCCGCCGACCGCAAGGTGATCCTGGCGCTGAACAAGATCGAC
GGGATCAAGCGCGACACCCTGCTGGCCGTGGCCAAGGACTTCTTCGACACCGGCGTCTATTCCGACGTCTTCATGATCAG
CGCCTCGACCGGCGCGGGCGTCGAGGACCTGACGGCCAAGCTGGTGTCGATGATGCCGGAAGGGCCCTGGCTCTATCCGG
AAGATCAGACCGCCGACCTGCCGGCGCGCCTGCTGGCCGCCGAGATCACCCGCGAGAAGGTCTATCTGCGCGTCCACGAG
GAACTGCCCTACGCCGCGACGGTCGAAACGACCGCCTTCGAGGAGCGCAAGGACGGCTCGGTGCGCATCGAGCAGACCAT
CCTGGTCGAGCGCGAAGGCCAGCGGGTCATCGTCATCGGCAAGGGCGGCCAGACCCTGAAATGGATCGGCCAGGCCTCGC
GCGAGGAACTGTGCGACATCCTCGACCGCAAGGTGCACCTGTTCCTGCACGTGAAGGTCAAGGAGAACTGGGCCGAGGAA
CGTGGTCTGTTCAGCGACATCGGCCTGGACTTCGATGTTTGA

Upstream 100 bases:

>100_bases
ATGATGCCGTCCTGAGGGGCTATTCCGCCATGAACTTTAAGCTGCTGAGGTTCAGCTTTCCACCCTCAACAGCCCCTTCG
AACGTCCGCTCTCACGTCGT

Downstream 100 bases:

>100_bases
CGCGCCGGCGCCGGCCGTGGAGCTGGACGCCTATTTCCGGCGTATCGGCTATGACGGCCCGCGCGAGCCGACCCTGGATA
CGCTGCGGGCCATCGCCTTC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKPLATAEPPSVLHARVMTDTTSKTRAGFAAIIGAPNAGKSTLVNRMVGAKVSIVTQKVQTTRFPVRGVAIEGDTQIVLV
DTPGIFSPRRRLDRAMVRAAWAGSEEAEATVHLVDVQAELASRADKATPGEYRSAQDVQTIIEGLKAADRKVILALNKID
GIKRDTLLAVAKDFFDTGVYSDVFMISASTGAGVEDLTAKLVSMMPEGPWLYPEDQTADLPARLLAAEITREKVYLRVHE
ELPYAATVETTAFEERKDGSVRIEQTILVEREGQRVIVIGKGGQTLKWIGQASREELCDILDRKVHLFLHVKVKENWAEE
RGLFSDIGLDFDV

Sequences:

>Translated_333_residues
MKPLATAEPPSVLHARVMTDTTSKTRAGFAAIIGAPNAGKSTLVNRMVGAKVSIVTQKVQTTRFPVRGVAIEGDTQIVLV
DTPGIFSPRRRLDRAMVRAAWAGSEEAEATVHLVDVQAELASRADKATPGEYRSAQDVQTIIEGLKAADRKVILALNKID
GIKRDTLLAVAKDFFDTGVYSDVFMISASTGAGVEDLTAKLVSMMPEGPWLYPEDQTADLPARLLAAEITREKVYLRVHE
ELPYAATVETTAFEERKDGSVRIEQTILVEREGQRVIVIGKGGQTLKWIGQASREELCDILDRKVHLFLHVKVKENWAEE
RGLFSDIGLDFDV
>Mature_333_residues
MKPLATAEPPSVLHARVMTDTTSKTRAGFAAIIGAPNAGKSTLVNRMVGAKVSIVTQKVQTTRFPVRGVAIEGDTQIVLV
DTPGIFSPRRRLDRAMVRAAWAGSEEAEATVHLVDVQAELASRADKATPGEYRSAQDVQTIIEGLKAADRKVILALNKID
GIKRDTLLAVAKDFFDTGVYSDVFMISASTGAGVEDLTAKLVSMMPEGPWLYPEDQTADLPARLLAAEITREKVYLRVHE
ELPYAATVETTAFEERKDGSVRIEQTILVEREGQRVIVIGKGGQTLKWIGQASREELCDILDRKVHLFLHVKVKENWAEE
RGLFSDIGLDFDV

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=341, Percent_Identity=27.8592375366569, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1788919, Length=308, Percent_Identity=36.6883116883117, Blast_Score=185, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24646434, Length=320, Percent_Identity=26.875, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36509; Mature: 36509

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLATAEPPSVLHARVMTDTTSKTRAGFAAIIGAPNAGKSTLVNRMVGAKVSIVTQKVQ
CCCCCCCCCCHHHEEEEEECCCCHHHCCEEEEEECCCCCHHHHHHHHHCCEEEEEHHHHH
TTRFPVRGVAIEGDTQIVLVDTPGIFSPRRRLDRAMVRAAWAGSEEAEATVHLVDVQAEL
HHCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHH
ASRADKATPGEYRSAQDVQTIIEGLKAADRKVILALNKIDGIKRDTLLAVAKDFFDTGVY
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
SDVFMISASTGAGVEDLTAKLVSMMPEGPWLYPEDQTADLPARLLAAEITREKVYLRVHE
CEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEEC
ELPYAATVETTAFEERKDGSVRIEQTILVEREGQRVIVIGKGGQTLKWIGQASREELCDI
CCCCEEEEEHHHHHCCCCCCEEEEEEEEEEECCCEEEEECCCCCEEHHHHCCCHHHHHHH
LDRKVHLFLHVKVKENWAEERGLFSDIGLDFDV
HCCEEEEEEEEEECCCHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MKPLATAEPPSVLHARVMTDTTSKTRAGFAAIIGAPNAGKSTLVNRMVGAKVSIVTQKVQ
CCCCCCCCCCHHHEEEEEECCCCHHHCCEEEEEECCCCCHHHHHHHHHCCEEEEEHHHHH
TTRFPVRGVAIEGDTQIVLVDTPGIFSPRRRLDRAMVRAAWAGSEEAEATVHLVDVQAEL
HHCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHH
ASRADKATPGEYRSAQDVQTIIEGLKAADRKVILALNKIDGIKRDTLLAVAKDFFDTGVY
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
SDVFMISASTGAGVEDLTAKLVSMMPEGPWLYPEDQTADLPARLLAAEITREKVYLRVHE
CEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEEC
ELPYAATVETTAFEERKDGSVRIEQTILVEREGQRVIVIGKGGQTLKWIGQASREELCDI
CCCCEEEEEHHHHHCCCCCCEEEEEEEEEEECCCEEEEECCCCCEEHHHHCCCHHHHHHH
LDRKVHLFLHVKVKENWAEERGLFSDIGLDFDV
HCCEEEEEEEEEECCCHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA