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The map label for this gene is eda [H]

Identifier: 16125742

GI number: 16125742

Start: 1654199

End: 1654873

Strand: Direct

Name: eda [H]

Synonym: CC_1495

Alternate gene names: 16125742

Gene position: 1654199-1654873 (Clockwise)

Preceding gene: 16125741

Following gene: 16125743

Centisome position: 41.18

GC content: 65.04

Gene sequence:

>675_bases
ATGGTGAAAGACCGTATGGCGGTGCTGACCGCCCTGATGGACCAGGGCGTCATTCCGGTGTTCTACCACCCGGACGTCGA
GGTCTGTAAGAACGTGATCCAGGCCTGCGCCGACGGCGGCGCGCCCTGCATCGAGTTCACCAACCGCGGCGATTTCGCCA
GCCACGTCTTCTATGAAGTGACCCGCTATTTCGCCGAGGCGGATCCGCGCGTGATCATGGGCGTGGGCTCGATCGTCGAC
GCGCCGACCGCCGGCATCTACATCGCCAACGGCGCCAAGTTCGTCGTCGGCCCGATCCTGAACGCCGACGTCGCCAAGGT
CTGCAACCGCCGCAAGATCCCGTACTCGCCGGGCTGCGGTTCGGCCTCGGAAATCTCGTACGCCGAAGAGCTGGGCTGCG
AGATCGTCAAGGTGTTCCCGGGTTCGTCGGTCGGCGGCCCCGATTTCGTCAAGGCGGTGCTGGGCCCGATGCCCTGGACC
CGCATCATGCCGACGGGCGGCGTCGATCCGGACGAGGCCTCGGTGAAGAAGTGGTTCGGCGCGGGCATCGTCGCCGCCGG
CATGGGCTCCAAGCTGATCACGCAAGAGATGCTGGACGCCAAGGACTACGCGGGCATCTCCAAGAAGGTCCGCGAGACGG
TAGACCTGATCAAGAAGGTTCGTGGGAAGGCCTAA

Upstream 100 bases:

>100_bases
GTCTAAGGGAACGCCCTGAGCCAATTCCGGCGAAATATTGCTCGCGCGGCGGCCCATGCGGCCCTTCGCGCAAGAACGAT
CCTTCGGGAAGGAGTTTGAG

Downstream 100 bases:

>100_bases
AACCAAATGACCGACAATATCCTCAACATCCGCCCGCCTTCGGAAACGAAGTGGGATTGCGCCAGCTTCGGTGAAGTGAT
GCTGCGTTTCGACCCGGGCT

Product: keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MVKDRMAVLTALMDQGVIPVFYHPDVEVCKNVIQACADGGAPCIEFTNRGDFASHVFYEVTRYFAEADPRVIMGVGSIVD
APTAGIYIANGAKFVVGPILNADVAKVCNRRKIPYSPGCGSASEISYAEELGCEIVKVFPGSSVGGPDFVKAVLGPMPWT
RIMPTGGVDPDEASVKKWFGAGIVAAGMGSKLITQEMLDAKDYAGISKKVRETVDLIKKVRGKA

Sequences:

>Translated_224_residues
MVKDRMAVLTALMDQGVIPVFYHPDVEVCKNVIQACADGGAPCIEFTNRGDFASHVFYEVTRYFAEADPRVIMGVGSIVD
APTAGIYIANGAKFVVGPILNADVAKVCNRRKIPYSPGCGSASEISYAEELGCEIVKVFPGSSVGGPDFVKAVLGPMPWT
RIMPTGGVDPDEASVKKWFGAGIVAAGMGSKLITQEMLDAKDYAGISKKVRETVDLIKKVRGKA
>Mature_224_residues
MVKDRMAVLTALMDQGVIPVFYHPDVEVCKNVIQACADGGAPCIEFTNRGDFASHVFYEVTRYFAEADPRVIMGVGSIVD
APTAGIYIANGAKFVVGPILNADVAKVCNRRKIPYSPGCGSASEISYAEELGCEIVKVFPGSSVGGPDFVKAVLGPMPWT
RIMPTGGVDPDEASVKKWFGAGIVAAGMGSKLITQEMLDAKDYAGISKKVRETVDLIKKVRGKA

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=182, Percent_Identity=29.6703296703297, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994954, Length=150, Percent_Identity=28, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 23837; Mature: 23837

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKDRMAVLTALMDQGVIPVFYHPDVEVCKNVIQACADGGAPCIEFTNRGDFASHVFYEV
CCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH
TRYFAEADPRVIMGVGSIVDAPTAGIYIANGAKFVVGPILNADVAKVCNRRKIPYSPGCG
HHHHHCCCCEEEEECCHHHCCCCCCEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCCCC
SASEISYAEELGCEIVKVFPGSSVGGPDFVKAVLGPMPWTRIMPTGGVDPDEASVKKWFG
CHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHC
AGIVAAGMGSKLITQEMLDAKDYAGISKKVRETVDLIKKVRGKA
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKDRMAVLTALMDQGVIPVFYHPDVEVCKNVIQACADGGAPCIEFTNRGDFASHVFYEV
CCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH
TRYFAEADPRVIMGVGSIVDAPTAGIYIANGAKFVVGPILNADVAKVCNRRKIPYSPGCG
HHHHHCCCCEEEEECCHHHCCCCCCEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCCCC
SASEISYAEELGCEIVKVFPGSSVGGPDFVKAVLGPMPWTRIMPTGGVDPDEASVKKWFG
CHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHC
AGIVAAGMGSKLITQEMLDAKDYAGISKKVRETVDLIKKVRGKA
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]