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The map label for this gene is erg3 [H]

Identifier: 16125693

GI number: 16125693

Start: 1594890

End: 1595792

Strand: Direct

Name: erg3 [H]

Synonym: CC_1444

Alternate gene names: 16125693

Gene position: 1594890-1595792 (Clockwise)

Preceding gene: 16125692

Following gene: 16125694

Centisome position: 39.7

GC content: 65.45

Gene sequence:

>903_bases
ATGCTGAAAGCCCCCTTCGATCCCGTCCAACTGGCGATCCCGTTTTTCGTCCTGGCCATCGTGCTGGAGATCCTGCTCGG
CCGCTTTGGCAAGGCCAAGGCCAACTACGAGACGCGCGACACCGCCATGTCGCTCAGCATGGGCCTGGGCAGCACCATCG
CCGGCGTGCTGTTCGGCGGCGTGATCTTCGCGGCTACGGTCTGGGTCTATGAGCATCGGCTGTTCACGATCCCGATGACC
GCGGTCTGGGCCTGGGTCGCGGTGTTCTTCCTGGAGGACCTGACCTATTACTGGTTCCACCGCATCGCCCACGAGCGCCG
GTTCTGGTGGGCCAGCCACGTCAACCACCACACCTCCACCCACTACAACCTGTCGACCGCGCTGCGTCAGACCTGGACCG
GCGGCGTGGCCGGGACCTGGCTCTTGTGGCTGCCGCTGGTGTTTTTCGGCTTCCCGCCGGCGATGGTGGCGATCCAAAAG
GGGATCAGCCTCGTCTACCAGTTCTGGATCCACACCGAGGCGGTGGGGCGCATGCCGCGCTGGTTCGAGGCGGTGTTCAA
CACGCCCTCGCATCACCGCGTCCACCACGCCCGCAACCCGCGCTATCTGGACGCCAACTACGCCGGCATCCTGATCATCT
GGGACCGCATGTTCGGCACCTTCATCCCCGAGGTCGACGAGGAGCCCTGCCGCTATGGCACGGTGAAGAACCTGGGCAAC
TTCAACCTGTTGCACAACGTCTTCCACGAGTGGGTCGGCATCGCCAAGGATGTGGCGGGCTCGAAGTCGCCGAAGGAGGC
GATCGGCTACCTGTTCGGCCCGCCCGGCTGGAGCCCGGACGGCTCGCGGGAGACCTCGCATACGCTCAAGGCCAAGTGGC
GGGCGCGGTTAGGGGGCGAGTAG

Upstream 100 bases:

>100_bases
CGCTGAAACCGGCCGCTGGACGTCTGACCGTTCGCGTCTCCGACGCTCGTCCCACCTTCGCCGTCAATGACGATGCCTGG
CCGCCGAAAGAGCTCGCCTG

Downstream 100 bases:

>100_bases
CGGTCGGTTCCTCCAAACCGACCCCATCGGATACGGCGATGGGCTCCACTGGTACGCCCATGTAGGCAATGGGGGATTAC
GGTGACAGTGCACTAATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLKAPFDPVQLAIPFFVLAIVLEILLGRFGKAKANYETRDTAMSLSMGLGSTIAGVLFGGVIFAATVWVYEHRLFTIPMT
AVWAWVAVFFLEDLTYYWFHRIAHERRFWWASHVNHHTSTHYNLSTALRQTWTGGVAGTWLLWLPLVFFGFPPAMVAIQK
GISLVYQFWIHTEAVGRMPRWFEAVFNTPSHHRVHHARNPRYLDANYAGILIIWDRMFGTFIPEVDEEPCRYGTVKNLGN
FNLLHNVFHEWVGIAKDVAGSKSPKEAIGYLFGPPGWSPDGSRETSHTLKAKWRARLGGE

Sequences:

>Translated_300_residues
MLKAPFDPVQLAIPFFVLAIVLEILLGRFGKAKANYETRDTAMSLSMGLGSTIAGVLFGGVIFAATVWVYEHRLFTIPMT
AVWAWVAVFFLEDLTYYWFHRIAHERRFWWASHVNHHTSTHYNLSTALRQTWTGGVAGTWLLWLPLVFFGFPPAMVAIQK
GISLVYQFWIHTEAVGRMPRWFEAVFNTPSHHRVHHARNPRYLDANYAGILIIWDRMFGTFIPEVDEEPCRYGTVKNLGN
FNLLHNVFHEWVGIAKDVAGSKSPKEAIGYLFGPPGWSPDGSRETSHTLKAKWRARLGGE
>Mature_300_residues
MLKAPFDPVQLAIPFFVLAIVLEILLGRFGKAKANYETRDTAMSLSMGLGSTIAGVLFGGVIFAATVWVYEHRLFTIPMT
AVWAWVAVFFLEDLTYYWFHRIAHERRFWWASHVNHHTSTHYNLSTALRQTWTGGVAGTWLLWLPLVFFGFPPAMVAIQK
GISLVYQFWIHTEAVGRMPRWFEAVFNTPSHHRVHHARNPRYLDANYAGILIIWDRMFGTFIPEVDEEPCRYGTVKNLGN
FNLLHNVFHEWVGIAKDVAGSKSPKEAIGYLFGPPGWSPDGSRETSHTLKAKWRARLGGE

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=278, Percent_Identity=38.1294964028777, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI25144659, Length=257, Percent_Identity=37.7431906614786, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 34248; Mature: 34248

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAPFDPVQLAIPFFVLAIVLEILLGRFGKAKANYETRDTAMSLSMGLGSTIAGVLFGG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
VIFAATVWVYEHRLFTIPMTAVWAWVAVFFLEDLTYYWFHRIAHERRFWWASHVNHHTST
HHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HYNLSTALRQTWTGGVAGTWLLWLPLVFFGFPPAMVAIQKGISLVYQFWIHTEAVGRMPR
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
WFEAVFNTPSHHRVHHARNPRYLDANYAGILIIWDRMFGTFIPEVDEEPCRYGTVKNLGN
HHHHHHCCCCCCHHHHCCCCCEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCHHCCCC
FNLLHNVFHEWVGIAKDVAGSKSPKEAIGYLFGPPGWSPDGSRETSHTLKAKWRARLGGE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKAPFDPVQLAIPFFVLAIVLEILLGRFGKAKANYETRDTAMSLSMGLGSTIAGVLFGG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
VIFAATVWVYEHRLFTIPMTAVWAWVAVFFLEDLTYYWFHRIAHERRFWWASHVNHHTST
HHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HYNLSTALRQTWTGGVAGTWLLWLPLVFFGFPPAMVAIQKGISLVYQFWIHTEAVGRMPR
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
WFEAVFNTPSHHRVHHARNPRYLDANYAGILIIWDRMFGTFIPEVDEEPCRYGTVKNLGN
HHHHHHCCCCCCHHHHCCCCCEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCHHCCCC
FNLLHNVFHEWVGIAKDVAGSKSPKEAIGYLFGPPGWSPDGSRETSHTLKAKWRARLGGE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]