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The map label for this gene is mcpA [H]

Identifier: 16125648

GI number: 16125648

Start: 1546711

End: 1548225

Strand: Direct

Name: mcpA [H]

Synonym: CC_1399

Alternate gene names: 16125648

Gene position: 1546711-1548225 (Clockwise)

Preceding gene: 16125644

Following gene: 16125650

Centisome position: 38.5

GC content: 68.45

Gene sequence:

>1515_bases
TTGACGCCACTGGCCAGTCTTGTCGCGGGCAACGCGGTCGCGAAACTGGCCGGAATCGCCACGGTCCTGGCGCTCGTAGC
GTTCGTGGCTTACCGGGTCGCGGCGGATCATTTCGGCCAGCGCCTGGTCTCAGCCCTTGTTCTGGTCGGACAGGTCGCCC
TGTTCGTGCTCGCCTTCAGCGGCAGTCCGCTGCAGTCCGAAGCGCGCATGGCCTTTCTCGCCGCGCTGGCCCTGTTGGTC
GCCTATGGCGATTGGCGGATCATCGCCGCCGGCGCGTTTGCGGTCGCAGCCTGTCATGGCGCTGCGGCGCTAGTCTCGCC
GCATGCGCTTGGCGGGAGCGGCGGTCTGATGGCGACGGCCTTCGCGATCGGGGTGACGGCCGCCACCGCCTGGTCGCTGA
TCTGGATGACGGCCGGCGTTTCGAGACTGTTCTCGACGGTGTCCGTCCGGACCCGTAACGCCGAGCGTGCGGCCGAACAG
GCCGAGGAGGCGCGTGAGGCGGTCGTGGCCGAACGCAATGCGCGCGAGCAGTCCGTCGCAGAGCGCGCCGCGCTGAAGGC
TGCGATGGAAGCCGAACAGAATCTGGTTGTGACCGAACTCGACGCGGCGATCACCAAGCTTGCCGACGGGGACCTGAGTT
GGCGGCTGCAGCAGAGCTTCGCCGAGCGCTATGAAGATCTGCGGGCCAACTTCAACCGGGCGCTGGAGCGACTGGAAGCC
GCCATGGGTGACGTGACCACGCGCGCTTCCACCATGACCGACGGCGTCAACGAGATGAGCCGCGCCTCCGACGAGTTGGC
GCGCCGAACCGAACAGCAGGCCGCCAGTCTGATCCAGACGGCCACGGCGCTGGGCGAGGTGACCGTCGCGGTGAACGAGA
CCGCTGAGAACGCCCGGCAAGCCAACGCTGCGGCGGAGGGCGCGCGCCAAGAGGCCGAGCGGTCCGACCCCGTGGTCACC
GAGGCTGTCGAGGCCATGACCCAGATCGAAACCTCCTCGGGCCAGATCGGTCGGATCATCGGCGTGATCGACGAGATCGC
GTTCCAGACGAACCTGCTGGCGCTCAACGCCGGCGTCGAGGCCGCACGGGCCGGCGAGTCGGGCAGGGGCTTCGCCGTCG
TCGCTCAGGAAGTTCGCGCCTTGGCGCAGCGCTCGGCCAACGCCGCCAGTGAGATCAAGACTCTGATCAGCGCTTCGACG
GCTCAGGTTTCGGCGGGGGTTGAGCGCGTTGCGCGCACGCGGGAAGCCTTGCAGCGTATCGTCGCGCGGGTCGCCGAGAT
CGACGGGCAGGTCAATGCGATCGCCCGCTCGGCGAACGATCAGGCGCAGAGCCTGCGCGACGTCAACACCACCGTCGGCG
AGATGGACCGGGTGGTGCAGCAGAACGCCGCCATGGTGGAAGAAACCACTGCGGCCGCTCACGCCCTGCGCTCCGAGGCG
CAAGACCTCAGCGACCGTATCGGCTTGTTCAAGATCACGGGCCGCATCGGCGGCGCCCGCCGTCAAGCGGCTTAG

Upstream 100 bases:

>100_bases
GGAATCTCCAGGGGCGGCCATGATCGAGTTCGACAGCATTGAGGCCCAGCGGCGCACGGGCGGGAAGCTGGTCTTGGCCT
GCAATGCGGCGATGGTGGCG

Downstream 100 bases:

>100_bases
TCGGCTTCTGGCATCTGCGCTGAACCGCCTTGCGGCGGCGGGTCCAGAACAGCGAACGCGCTGGAGCGCTTTCCGATCCG
TATGAAGCGGTGATCGAATG

Product: methyl-accepting chemotaxis protein McpP

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MTPLASLVAGNAVAKLAGIATVLALVAFVAYRVAADHFGQRLVSALVLVGQVALFVLAFSGSPLQSEARMAFLAALALLV
AYGDWRIIAAGAFAVAACHGAAALVSPHALGGSGGLMATAFAIGVTAATAWSLIWMTAGVSRLFSTVSVRTRNAERAAEQ
AEEAREAVVAERNAREQSVAERAALKAAMEAEQNLVVTELDAAITKLADGDLSWRLQQSFAERYEDLRANFNRALERLEA
AMGDVTTRASTMTDGVNEMSRASDELARRTEQQAASLIQTATALGEVTVAVNETAENARQANAAAEGARQEAERSDPVVT
EAVEAMTQIETSSGQIGRIIGVIDEIAFQTNLLALNAGVEAARAGESGRGFAVVAQEVRALAQRSANAASEIKTLISAST
AQVSAGVERVARTREALQRIVARVAEIDGQVNAIARSANDQAQSLRDVNTTVGEMDRVVQQNAAMVEETTAAAHALRSEA
QDLSDRIGLFKITGRIGGARRQAA

Sequences:

>Translated_504_residues
MTPLASLVAGNAVAKLAGIATVLALVAFVAYRVAADHFGQRLVSALVLVGQVALFVLAFSGSPLQSEARMAFLAALALLV
AYGDWRIIAAGAFAVAACHGAAALVSPHALGGSGGLMATAFAIGVTAATAWSLIWMTAGVSRLFSTVSVRTRNAERAAEQ
AEEAREAVVAERNAREQSVAERAALKAAMEAEQNLVVTELDAAITKLADGDLSWRLQQSFAERYEDLRANFNRALERLEA
AMGDVTTRASTMTDGVNEMSRASDELARRTEQQAASLIQTATALGEVTVAVNETAENARQANAAAEGARQEAERSDPVVT
EAVEAMTQIETSSGQIGRIIGVIDEIAFQTNLLALNAGVEAARAGESGRGFAVVAQEVRALAQRSANAASEIKTLISAST
AQVSAGVERVARTREALQRIVARVAEIDGQVNAIARSANDQAQSLRDVNTTVGEMDRVVQQNAAMVEETTAAAHALRSEA
QDLSDRIGLFKITGRIGGARRQAA
>Mature_503_residues
TPLASLVAGNAVAKLAGIATVLALVAFVAYRVAADHFGQRLVSALVLVGQVALFVLAFSGSPLQSEARMAFLAALALLVA
YGDWRIIAAGAFAVAACHGAAALVSPHALGGSGGLMATAFAIGVTAATAWSLIWMTAGVSRLFSTVSVRTRNAERAAEQA
EEAREAVVAERNAREQSVAERAALKAAMEAEQNLVVTELDAAITKLADGDLSWRLQQSFAERYEDLRANFNRALERLEAA
MGDVTTRASTMTDGVNEMSRASDELARRTEQQAASLIQTATALGEVTVAVNETAENARQANAAAEGARQEAERSDPVVTE
AVEAMTQIETSSGQIGRIIGVIDEIAFQTNLLALNAGVEAARAGESGRGFAVVAQEVRALAQRSANAASEIKTLISASTA
QVSAGVERVARTREALQRIVARVAEIDGQVNAIARSANDQAQSLRDVNTTVGEMDRVVQQNAAMVEETTAAAHALRSEAQ
DLSDRIGLFKITGRIGGARRQAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=308, Percent_Identity=43.5064935064935, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1788194, Length=255, Percent_Identity=44.7058823529412, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1787690, Length=293, Percent_Identity=40.9556313993174, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1788195, Length=241, Percent_Identity=44.3983402489627, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=35.6, Blast_Score=149, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 52765; Mature: 52634

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLASLVAGNAVAKLAGIATVLALVAFVAYRVAADHFGQRLVSALVLVGQVALFVLAFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSPLQSEARMAFLAALALLVAYGDWRIIAAGAFAVAACHGAAALVSPHALGGSGGLMATA
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FAIGVTAATAWSLIWMTAGVSRLFSTVSVRTRNAERAAEQAEEAREAVVAERNAREQSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
ERAALKAAMEAEQNLVVTELDAAITKLADGDLSWRLQQSFAERYEDLRANFNRALERLEA
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGDVTTRASTMTDGVNEMSRASDELARRTEQQAASLIQTATALGEVTVAVNETAENARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHH
ANAAAEGARQEAERSDPVVTEAVEAMTQIETSSGQIGRIIGVIDEIAFQTNLLALNAGVE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCH
AARAGESGRGFAVVAQEVRALAQRSANAASEIKTLISASTAQVSAGVERVARTREALQRI
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VARVAEIDGQVNAIARSANDQAQSLRDVNTTVGEMDRVVQQNAAMVEETTAAAHALRSEA
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDLSDRIGLFKITGRIGGARRQAA
HHHHHCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TPLASLVAGNAVAKLAGIATVLALVAFVAYRVAADHFGQRLVSALVLVGQVALFVLAFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSPLQSEARMAFLAALALLVAYGDWRIIAAGAFAVAACHGAAALVSPHALGGSGGLMATA
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FAIGVTAATAWSLIWMTAGVSRLFSTVSVRTRNAERAAEQAEEAREAVVAERNAREQSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
ERAALKAAMEAEQNLVVTELDAAITKLADGDLSWRLQQSFAERYEDLRANFNRALERLEA
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGDVTTRASTMTDGVNEMSRASDELARRTEQQAASLIQTATALGEVTVAVNETAENARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHH
ANAAAEGARQEAERSDPVVTEAVEAMTQIETSSGQIGRIIGVIDEIAFQTNLLALNAGVE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCH
AARAGESGRGFAVVAQEVRALAQRSANAASEIKTLISASTAQVSAGVERVARTREALQRI
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VARVAEIDGQVNAIARSANDQAQSLRDVNTTVGEMDRVVQQNAAMVEETTAAAHALRSEA
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDLSDRIGLFKITGRIGGARRQAA
HHHHHCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]