Click here to switch to the map view.

The map label for this gene is ctaA

Identifier: 16125623

GI number: 16125623

Start: 1524183

End: 1525214

Strand: Direct

Name: ctaA

Synonym: CC_1374

Alternate gene names: 16125623

Gene position: 1524183-1525214 (Clockwise)

Preceding gene: 16125622

Following gene: 16125625

Centisome position: 37.94

GC content: 66.86

Gene sequence:

>1032_bases
ATGACGTCTTTCCTGCGTTCCGACCGCTCGCGTCCCGTCGCGATCTGGCTTTTCATCGTCGCCGCCATGGTGTTCGCCAT
GGTCGTTGTCGGCGGGGCGACCCGTCTGACCGACTCGGGTCTGTCGATCACCGAGTGGCAGCCGATCATGGGCGCCTTGC
CGCCCATGTCAGAGCAGGCCTGGCGAGAGAGTTTCGAGCTCTACAAGCAGATCCCTCAGTTCCAGCTGGTCAATCCGGAT
ATGACCCTGGAGGGCTACAAGGAAATCTTCTGGTGGGAGTGGGCCCACCGTTTGCTGGGGCGAACCGTCGGGGCGGTCTA
CGCCATTCCGCTGATCGTTTTCCTGATCCGTCGCGATATTCCGCGCCGTCTGATCTGGCGTTGCGCCGCGATGCTGGGCC
TGGGCGGCCTGCAGGGCCTAGTGGGCTGGTGGATGGTGTCCAGCGGCCTTTCCGAGCGGGTTTCGGTGGCCCCGGAACGG
CTGATGACCCACCTGGGCCTCGCCCTTGCGCTGTTTGTCCTGTTGATCTGGACCGCCCTTGACGCCTGGAACGGCTCACC
GCGCGTCGAGGAGCGCAGCCCCTGGCGCGGCTGGGCGCTGGCGTTCCTGGGCGCCGTCTTCTTCCAGAGCCTGCTGGGCG
CCCTTGTCGCCGGCAATGACGCGGGGTTTGTCTACAACGACTGGCCGCTGATGAACGGGCGGTTCTTCCCGGGTGACTAT
GGCGGTGCGGGCCTGTGGGGAACGCTGGCCCACAGCCAGGCCGCAGTTCAGTTCAACCACCGTATCTTCGCCTACGCCCT
GCTCCTGGCCGCCGTCGTGTTGGTCGTCCTGGCGCGGCGCGATCGTCTGCTGGTGGGTCAGGGCAAAAGCCTCGCCACGG
CCGTCGCGGCCGTTGTCTTCCTGCAGGCCGCCCTTGGCGTCTGGACGCTGATGGCGGCGGTCCCCATCAGCCTGGGCGTG
CTTCATCAGGCCGGCGCGGCCGTTCTGCTCGCCGTTGCGACCGCCTTCGCCTGGCGGGTTCGCCGCCCTTGA

Upstream 100 bases:

>100_bases
CTCCGTCATGTCGGGCCACACAGAGATTGATGCGGGCCATTGTCGGGCGTAGGGAAGGAGCCGCCGCAATTCGGCCCACA
AGTGACGCTTTTCCGACCCC

Downstream 100 bases:

>100_bases
CCAAGCCGCAGCTTGGAAAGGGCGGCGAGACGCGCGCCGACTAGACCTTCACCGCGCCCCACGGCCCGGAAATGGCCAGG
GTGAAGCCTGGGTTCTGCAG

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTSFLRSDRSRPVAIWLFIVAAMVFAMVVVGGATRLTDSGLSITEWQPIMGALPPMSEQAWRESFELYKQIPQFQLVNPD
MTLEGYKEIFWWEWAHRLLGRTVGAVYAIPLIVFLIRRDIPRRLIWRCAAMLGLGGLQGLVGWWMVSSGLSERVSVAPER
LMTHLGLALALFVLLIWTALDAWNGSPRVEERSPWRGWALAFLGAVFFQSLLGALVAGNDAGFVYNDWPLMNGRFFPGDY
GGAGLWGTLAHSQAAVQFNHRIFAYALLLAAVVLVVLARRDRLLVGQGKSLATAVAAVVFLQAALGVWTLMAAVPISLGV
LHQAGAAVLLAVATAFAWRVRRP

Sequences:

>Translated_343_residues
MTSFLRSDRSRPVAIWLFIVAAMVFAMVVVGGATRLTDSGLSITEWQPIMGALPPMSEQAWRESFELYKQIPQFQLVNPD
MTLEGYKEIFWWEWAHRLLGRTVGAVYAIPLIVFLIRRDIPRRLIWRCAAMLGLGGLQGLVGWWMVSSGLSERVSVAPER
LMTHLGLALALFVLLIWTALDAWNGSPRVEERSPWRGWALAFLGAVFFQSLLGALVAGNDAGFVYNDWPLMNGRFFPGDY
GGAGLWGTLAHSQAAVQFNHRIFAYALLLAAVVLVVLARRDRLLVGQGKSLATAVAAVVFLQAALGVWTLMAAVPISLGV
LHQAGAAVLLAVATAFAWRVRRP
>Mature_342_residues
TSFLRSDRSRPVAIWLFIVAAMVFAMVVVGGATRLTDSGLSITEWQPIMGALPPMSEQAWRESFELYKQIPQFQLVNPDM
TLEGYKEIFWWEWAHRLLGRTVGAVYAIPLIVFLIRRDIPRRLIWRCAAMLGLGGLQGLVGWWMVSSGLSERVSVAPERL
MTHLGLALALFVLLIWTALDAWNGSPRVEERSPWRGWALAFLGAVFFQSLLGALVAGNDAGFVYNDWPLMNGRFFPGDYG
GAGLWGTLAHSQAAVQFNHRIFAYALLLAAVVLVVLARRDRLLVGQGKSLATAVAAVVFLQAALGVWTLMAAVPISLGVL
HQAGAAVLLAVATAFAWRVRRP

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=343, Percent_Identity=37.0262390670554, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI17921987, Length=281, Percent_Identity=38.0782918149466, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17536069, Length=354, Percent_Identity=34.4632768361582, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320989, Length=374, Percent_Identity=37.9679144385027, Blast_Score=228, Evalue=1e-60,
Organism=Drosophila melanogaster, GI19922860, Length=349, Percent_Identity=34.6704871060172, Blast_Score=181, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_CAUCN (B8H551)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002516811.1
- GeneID:   7330168
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01438
- OMA:   GLSIVEW
- ProtClustDB:   CLSK2752647
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 37771; Mature: 37640

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: BINDING 322-322

Signals:

None

Transmembrane regions:

HASH(0xea19330)-; HASH(0xeb0b704)-; HASH(0xea4edec)-; HASH(0xebe38a0)-; HASH(0xe4a128c)-; HASH(0xdf41ea4)-; HASH(0xe7e3a0c)-; HASH(0xeb3050c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFLRSDRSRPVAIWLFIVAAMVFAMVVVGGATRLTDSGLSITEWQPIMGALPPMSEQA
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHCCCCCCCHHH
WRESFELYKQIPQFQLVNPDMTLEGYKEIFWWEWAHRLLGRTVGAVYAIPLIVFLIRRDI
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRRLIWRCAAMLGLGGLQGLVGWWMVSSGLSERVSVAPERLMTHLGLALALFVLLIWTAL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAWNGSPRVEERSPWRGWALAFLGAVFFQSLLGALVAGNDAGFVYNDWPLMNGRFFPGDY
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCC
GGAGLWGTLAHSQAAVQFNHRIFAYALLLAAVVLVVLARRDRLLVGQGKSLATAVAAVVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHH
LQAALGVWTLMAAVPISLGVLHQAGAAVLLAVATAFAWRVRRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
TSFLRSDRSRPVAIWLFIVAAMVFAMVVVGGATRLTDSGLSITEWQPIMGALPPMSEQA
CCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHCCCCCCCHHH
WRESFELYKQIPQFQLVNPDMTLEGYKEIFWWEWAHRLLGRTVGAVYAIPLIVFLIRRDI
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRRLIWRCAAMLGLGGLQGLVGWWMVSSGLSERVSVAPERLMTHLGLALALFVLLIWTAL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAWNGSPRVEERSPWRGWALAFLGAVFFQSLLGALVAGNDAGFVYNDWPLMNGRFFPGDY
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCC
GGAGLWGTLAHSQAAVQFNHRIFAYALLLAAVVLVVLARRDRLLVGQGKSLATAVAAVVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHH
LQAALGVWTLMAAVPISLGVLHQAGAAVLLAVATAFAWRVRRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA