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The map label for this gene is acdA [H]

Identifier: 16125599

GI number: 16125599

Start: 1504005

End: 1505144

Strand: Direct

Name: acdA [H]

Synonym: CC_1350

Alternate gene names: 16125599

Gene position: 1504005-1505144 (Clockwise)

Preceding gene: 16125598

Following gene: 16125600

Centisome position: 37.44

GC content: 65.26

Gene sequence:

>1140_bases
ATGGATTTCGCGCTGAACGAAGATCAAGTCGCAATCCAGGACGCCGCCCGCGCTTTCGCCGAAGGACAGCTTGCCCCGCA
TTCGGCCGACTGGGACGAAAATAAGCACTTCCCGGTCGACGTGCTGCGCCAGGCGGCCGAGCTGGGCTTCGCCGGCATCT
ATGTGAACGAAGACGTTGGCGGCAGCGGGCTTTCGCGCCTCGACGCCTCGATCATTTTCGAGGCGCTCAGCTATGGCGAT
GTGCCGGTCGCCGCGTATCTCACCATCCACAACATGGCGTCGTGGATGATCGACCGCTTCGGCTCGGACGATCTGCGCCA
GCGCTATCTGCCGCGCCTGACGACCATGGAGCTGATCGCCAGCTACTGTCTGACCGAACCGGGCTCGGGCTCGGACGCAG
CGGCGATGCGTACAACCGCCAAGCTTGACGGCGACCACTATGTCCTCAACGGCGGCAAGGCTTTCATTTCGGGCGGTGGC
GTCTCGGACATCTATGTCGTCATGGCGCGCACGGGCGGCGAGGGGGCCAAGGGCGTCTCGGCCTTCGTGGTCGAGAAGGG
TATGGAGGGGCTGAGCTTCGGCGCCAATGAGCGGAAGATGGGCTGGAACGCCCAGCCGACCGCTCAGGTCAATTTCGACA
ACTGCCGCGTGCCGGTCGCCAACCGCATCGGCCAGGAAGGCGAAGGCTTCCGCTTCGCCATGATGGGGCTGGACGGCGGT
CGCCTGAACATCGCGTCGTGCTCGCTGGGCGGGGCCCAGTTCGCGCTCGACACAGCCAAGGCGTATCTCGAGACCCGCAA
CCAGTTCGGCCGCCCGCTGAAGGACTTCCAGGCCTTGCAGTTCAAGCTGGCCGACATGGCGACTGAACTGGAAGCCGCCC
GGCTGATGGTGCGCCGCGCCGCCCACGCGCTGGACAGCAAGCACCCTGAAGCGACCAAGCTGTGCGCCATGGCCAAGCGC
TTCGCCACCGACGCCGGCTTCCAGGTGGCCAATGACGCCTTGCAGCTGCATGGCGGCTACGGCTACCTCCAGGACTATCC
GCTGGAGCGCCTCGTCCGCGACCTGCGGGTGCACCAGATCCTGGAAGGGACCAACGAGATCATGCGCGTCATCATCGCCC
GCGAGATGTTCCGCCAATGA

Upstream 100 bases:

>100_bases
TGAAATGGCGGTGGCGCATGATTGACACCGCGTCGCCGGCGCGGCACGTCAGCCATCAAAGAGGCGAGGGCGGTTCTGCC
CCGAACGGGAGGAAGTGCGC

Downstream 100 bases:

>100_bases
GCGTCGGATGATCTATCTCTGTCGTCACGGCCAGACCTTCCACAATCGCGAGGGGCGACTGCAGGGGCGGACGGAGTCCG
ATCTGACGCCGCTGGGGCTT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDFALNEDQVAIQDAARAFAEGQLAPHSADWDENKHFPVDVLRQAAELGFAGIYVNEDVGGSGLSRLDASIIFEALSYGD
VPVAAYLTIHNMASWMIDRFGSDDLRQRYLPRLTTMELIASYCLTEPGSGSDAAAMRTTAKLDGDHYVLNGGKAFISGGG
VSDIYVVMARTGGEGAKGVSAFVVEKGMEGLSFGANERKMGWNAQPTAQVNFDNCRVPVANRIGQEGEGFRFAMMGLDGG
RLNIASCSLGGAQFALDTAKAYLETRNQFGRPLKDFQALQFKLADMATELEAARLMVRRAAHALDSKHPEATKLCAMAKR
FATDAGFQVANDALQLHGGYGYLQDYPLERLVRDLRVHQILEGTNEIMRVIIAREMFRQ

Sequences:

>Translated_379_residues
MDFALNEDQVAIQDAARAFAEGQLAPHSADWDENKHFPVDVLRQAAELGFAGIYVNEDVGGSGLSRLDASIIFEALSYGD
VPVAAYLTIHNMASWMIDRFGSDDLRQRYLPRLTTMELIASYCLTEPGSGSDAAAMRTTAKLDGDHYVLNGGKAFISGGG
VSDIYVVMARTGGEGAKGVSAFVVEKGMEGLSFGANERKMGWNAQPTAQVNFDNCRVPVANRIGQEGEGFRFAMMGLDGG
RLNIASCSLGGAQFALDTAKAYLETRNQFGRPLKDFQALQFKLADMATELEAARLMVRRAAHALDSKHPEATKLCAMAKR
FATDAGFQVANDALQLHGGYGYLQDYPLERLVRDLRVHQILEGTNEIMRVIIAREMFRQ
>Mature_379_residues
MDFALNEDQVAIQDAARAFAEGQLAPHSADWDENKHFPVDVLRQAAELGFAGIYVNEDVGGSGLSRLDASIIFEALSYGD
VPVAAYLTIHNMASWMIDRFGSDDLRQRYLPRLTTMELIASYCLTEPGSGSDAAAMRTTAKLDGDHYVLNGGKAFISGGG
VSDIYVVMARTGGEGAKGVSAFVVEKGMEGLSFGANERKMGWNAQPTAQVNFDNCRVPVANRIGQEGEGFRFAMMGLDGG
RLNIASCSLGGAQFALDTAKAYLETRNQFGRPLKDFQALQFKLADMATELEAARLMVRRAAHALDSKHPEATKLCAMAKR
FATDAGFQVANDALQLHGGYGYLQDYPLERLVRDLRVHQILEGTNEIMRVIIAREMFRQ

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=60.5333333333333, Blast_Score=486, Evalue=1e-137,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=37.7308707124011, Blast_Score=265, Evalue=5e-71,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=37.7308707124011, Blast_Score=265, Evalue=6e-71,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=40.6914893617021, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=37.0666666666667, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI4501857, Length=367, Percent_Identity=33.7874659400545, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=35.1063829787234, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI21361497, Length=355, Percent_Identity=37.1830985915493, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=36.6071428571429, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI76496475, Length=336, Percent_Identity=36.3095238095238, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI4557235, Length=336, Percent_Identity=36.3095238095238, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI4503943, Length=381, Percent_Identity=30.7086614173228, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI7669494, Length=362, Percent_Identity=30.6629834254144, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI38505218, Length=363, Percent_Identity=27.5482093663912, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=28.2229965156794, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=28.2229965156794, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=29.5811518324607, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1786223, Length=383, Percent_Identity=27.6762402088773, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87082384, Length=292, Percent_Identity=28.0821917808219, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=53.8461538461538, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=37.8590078328982, Blast_Score=271, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=37.2703412073491, Blast_Score=270, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=34.6456692913386, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=36.5591397849462, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=38, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=35.4838709677419, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=35.0649350649351, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI71990804, Length=317, Percent_Identity=36.9085173501577, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71985192, Length=282, Percent_Identity=37.9432624113475, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=40, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=33.2116788321168, Blast_Score=170, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17534353, Length=373, Percent_Identity=29.2225201072386, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17505929, Length=380, Percent_Identity=30.5263157894737, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=29.8666666666667, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=32.5, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17562446, Length=285, Percent_Identity=30.8771929824561, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI86563381, Length=325, Percent_Identity=27.3846153846154, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=325, Percent_Identity=27.3846153846154, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531913, Length=175, Percent_Identity=29.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=36.8421052631579, Blast_Score=261, Evalue=4e-70,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=38.0952380952381, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=39.2572944297082, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=36.0215053763441, Blast_Score=241, Evalue=8e-64,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=35.2631578947368, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=35.4166666666667, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=29.7650130548303, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24652780, Length=331, Percent_Identity=24.4712990936556, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41352; Mature: 41352

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFALNEDQVAIQDAARAFAEGQLAPHSADWDENKHFPVDVLRQAAELGFAGIYVNEDVG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCC
GSGLSRLDASIIFEALSYGDVPVAAYLTIHNMASWMIDRFGSDDLRQRYLPRLTTMELIA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHH
SYCLTEPGSGSDAAAMRTTAKLDGDHYVLNGGKAFISGGGVSDIYVVMARTGGEGAKGVS
HHHCCCCCCCCCHHHHHHHHEECCCEEEEECCEEEEECCCCCEEEEEEEECCCCCCCHHH
AFVVEKGMEGLSFGANERKMGWNAQPTAQVNFDNCRVPVANRIGQEGEGFRFAMMGLDGG
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCCEEEEEEECCCC
RLNIASCSLGGAQFALDTAKAYLETRNQFGRPLKDFQALQFKLADMATELEAARLMVRRA
EEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHALDSKHPEATKLCAMAKRFATDAGFQVANDALQLHGGYGYLQDYPLERLVRDLRVHQI
HHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCHHEECCCCCCHHCCCHHHHHHHHHHHHH
LEGTNEIMRVIIAREMFRQ
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFALNEDQVAIQDAARAFAEGQLAPHSADWDENKHFPVDVLRQAAELGFAGIYVNEDVG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCC
GSGLSRLDASIIFEALSYGDVPVAAYLTIHNMASWMIDRFGSDDLRQRYLPRLTTMELIA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHH
SYCLTEPGSGSDAAAMRTTAKLDGDHYVLNGGKAFISGGGVSDIYVVMARTGGEGAKGVS
HHHCCCCCCCCCHHHHHHHHEECCCEEEEECCEEEEECCCCCEEEEEEEECCCCCCCHHH
AFVVEKGMEGLSFGANERKMGWNAQPTAQVNFDNCRVPVANRIGQEGEGFRFAMMGLDGG
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCCEEEEEEECCCC
RLNIASCSLGGAQFALDTAKAYLETRNQFGRPLKDFQALQFKLADMATELEAARLMVRRA
EEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHALDSKHPEATKLCAMAKRFATDAGFQVANDALQLHGGYGYLQDYPLERLVRDLRVHQI
HHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCHHEECCCCCCHHCCCHHHHHHHHHHHHH
LEGTNEIMRVIIAREMFRQ
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]