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The map label for this gene is ygcA [C]

Identifier: 16125575

GI number: 16125575

Start: 1477954

End: 1479201

Strand: Direct

Name: ygcA [C]

Synonym: CC_1326

Alternate gene names: 16125575

Gene position: 1477954-1479201 (Clockwise)

Preceding gene: 16125573

Following gene: 16125576

Centisome position: 36.79

GC content: 69.71

Gene sequence:

>1248_bases
ATGCAAGATTTGACGATCAACGCCATCGGCGCCCAGGGCGACGGCCTCGCGCGCACCGCCGACGGCAAGCCGGCCTTTGT
TCCCCTGACCCTGCCGGGCGAGGTGGTCCGCGCCAAGATGGACGGCGCGCGCGGCGAGGTCGTCGAGATCCTGGCGCCGA
GTCCGGAACGGGTCGCGCCGGCATGCCGCCACTACGGAGTCTGCGGCGGTTGCGCGCTTCAGCACTGGGCCGCTGAGCCC
TATCGCGCCTGGAAGGCCGAACAGGTTCGGTTGCAGCTGTCGATGGAGGGCCTTGAGACCGAAATCCTCCCGACCTTCGC
GGCGCCGCCGGCGTCGCGGCGTCGCGTGGCGCTGCATGCTCGCAAAGGGGGCAAGGGGCAGGGGGCGCGCCTCGGATTCA
AGGAGCGGCGCTCGTGGAACCTCGTGTCGATCGAAGAGTGTCCCGTCACCGATCCGCGCCTAGTGGCCGCGCTGCCGGCC
CTGGCGCGTTTGGCTGAACCCTTCCTGGAGCATCCGAAGTCGGCGCCGACCCTCCATGTCACGCTCACCGCCACGGGCCT
CGATATCGACATCACCGGCGTGGAGCGGAAAAGTGGCGGGCTGTCGGCCGACGCCCGCATGCGCGCGGCGATGGCGGCGG
GCGAAGGCGATTTTGCCCGTGTCACTCTGGCGGGCGAGACGATCTATGGCGCGCGGCAGCCCTTGGTGAAGCTTGGGCAG
GCTGTGGTCGCCCTGCCGCCCGGAAGCTTTTTGCAGGCCGTGCCCGCCGCCGAGAAGGCGATGGTCGAGCTGGCGGTGGC
CGAGGCCCAGGGCGCGAGCCGCGTTGCGGATCTCTACTGCGGCGTCGGCACCTTCACCTTCCCGCTGGCCGAGGTGGCCC
AGGTCTACGCTGCGGAGATGAGCGCGCCGGCCATCACGGCGCTGAAGGCGGCGATCGGCGGGGCGCCGGGGCTCAAGCCG
ATCACCGCCGAGGCGCGGGATCTCGTGCGGCGTCCAGTGCTCAGCACCGAGCTGGCCAAGACCGATGTCGTGGTCATCGA
TCCGCCGCGCGCCGGCGCCGCCGAGCAAACGGTCGAGATCGCCAAGTCCAAGGTCGCCAAGGTGTTGGGGGTGTCTTGCA
ATCCACAGACCTTCGCCAAGGACGCGCGGGTGCTGGTCGACGCCGGCTTCAAGCTTGTGAGGGTGACGCCGGTGGACCAG
TTCGTCTGGTCGCCGCATATTGAGCTGGTCGGAGTCTTCACCCGGTAG

Upstream 100 bases:

>100_bases
AACATGAATGGAGCCTGACAGACTTCGGCTGTTTGACGCCGGACGCACAAAAACTGCTGCAGCGCGCGCCCTGGCCTGGG
TTTTGGGGTATGGACGGCGC

Downstream 100 bases:

>100_bases
GGGGCGATGGATCAGTCCACCCGCGCACGCACGCGCACGGCCTTTGCGATAGACGCGGTCGGCCAGGGCGCCAAGGCGGC
GGTCAAGGCCGTATGGTGGA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MQDLTINAIGAQGDGLARTADGKPAFVPLTLPGEVVRAKMDGARGEVVEILAPSPERVAPACRHYGVCGGCALQHWAAEP
YRAWKAEQVRLQLSMEGLETEILPTFAAPPASRRRVALHARKGGKGQGARLGFKERRSWNLVSIEECPVTDPRLVAALPA
LARLAEPFLEHPKSAPTLHVTLTATGLDIDITGVERKSGGLSADARMRAAMAAGEGDFARVTLAGETIYGARQPLVKLGQ
AVVALPPGSFLQAVPAAEKAMVELAVAEAQGASRVADLYCGVGTFTFPLAEVAQVYAAEMSAPAITALKAAIGGAPGLKP
ITAEARDLVRRPVLSTELAKTDVVVIDPPRAGAAEQTVEIAKSKVAKVLGVSCNPQTFAKDARVLVDAGFKLVRVTPVDQ
FVWSPHIELVGVFTR

Sequences:

>Translated_415_residues
MQDLTINAIGAQGDGLARTADGKPAFVPLTLPGEVVRAKMDGARGEVVEILAPSPERVAPACRHYGVCGGCALQHWAAEP
YRAWKAEQVRLQLSMEGLETEILPTFAAPPASRRRVALHARKGGKGQGARLGFKERRSWNLVSIEECPVTDPRLVAALPA
LARLAEPFLEHPKSAPTLHVTLTATGLDIDITGVERKSGGLSADARMRAAMAAGEGDFARVTLAGETIYGARQPLVKLGQ
AVVALPPGSFLQAVPAAEKAMVELAVAEAQGASRVADLYCGVGTFTFPLAEVAQVYAAEMSAPAITALKAAIGGAPGLKP
ITAEARDLVRRPVLSTELAKTDVVVIDPPRAGAAEQTVEIAKSKVAKVLGVSCNPQTFAKDARVLVDAGFKLVRVTPVDQ
FVWSPHIELVGVFTR
>Mature_415_residues
MQDLTINAIGAQGDGLARTADGKPAFVPLTLPGEVVRAKMDGARGEVVEILAPSPERVAPACRHYGVCGGCALQHWAAEP
YRAWKAEQVRLQLSMEGLETEILPTFAAPPASRRRVALHARKGGKGQGARLGFKERRSWNLVSIEECPVTDPRLVAALPA
LARLAEPFLEHPKSAPTLHVTLTATGLDIDITGVERKSGGLSADARMRAAMAAGEGDFARVTLAGETIYGARQPLVKLGQ
AVVALPPGSFLQAVPAAEKAMVELAVAEAQGASRVADLYCGVGTFTFPLAEVAQVYAAEMSAPAITALKAAIGGAPGLKP
ITAEARDLVRRPVLSTELAKTDVVVIDPPRAGAAEQTVEIAKSKVAKVLGVSCNPQTFAKDARVLVDAGFKLVRVTPVDQ
FVWSPHIELVGVFTR

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain

Homologues:

Organism=Escherichia coli, GI1789148, Length=432, Percent_Identity=30.5555555555556, Blast_Score=159, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1326_CAUCR (Q9A8M7)

Other databases:

- EMBL:   AE005673
- PIR:   G87413
- RefSeq:   NP_420139.1
- ProteinModelPortal:   Q9A8M7
- SMR:   Q9A8M7
- GeneID:   941584
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_1326
- NMPDR:   fig|190650.1.peg.1319
- TIGR:   CC_1326
- HOGENOM:   HBG690163
- OMA:   VVFVEGA
- ProtClustDB:   CLSK890349
- InterPro:   IPR016027
- InterPro:   IPR002792
- InterPro:   IPR010280

Pfam domain/function: PF05958 tRNA_U5-meth_tr; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 43670; Mature: 43670

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50926 TRAM; PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 373-373 BINDING 252-252 BINDING 279-279 BINDING 299-299 BINDING 347-347

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLTINAIGAQGDGLARTADGKPAFVPLTLPGEVVRAKMDGARGEVVEILAPSPERVAP
CCCEEEEEECCCCCCCEEECCCCCEEEEEECCHHHHHHHCCCCCCCEEEEECCCCHHHHH
ACRHYGVCGGCALQHWAAEPYRAWKAEQVRLQLSMEGLETEILPTFAAPPASRRRVALHA
HHHHCCCCCCHHHHHHCCCHHHHCCCEEEEEEEEECCCCEEEEECCCCCCCCCCEEEEEE
RKGGKGQGARLGFKERRSWNLVSIEECPVTDPRLVAALPALARLAEPFLEHPKSAPTLHV
CCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TLTATGLDIDITGVERKSGGLSADARMRAAMAAGEGDFARVTLAGETIYGARQPLVKLGQ
EEEEECCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCC
AVVALPPGSFLQAVPAAEKAMVELAVAEAQGASRVADLYCGVGTFTFPLAEVAQVYAAEM
EEEEECCCHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHC
SAPAITALKAAIGGAPGLKPITAEARDLVRRPVLSTELAKTDVVVIDPPRAGAAEQTVEI
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCEEEECCCCCCCHHHHHHH
AKSKVAKVLGVSCNPQTFAKDARVLVDAGFKLVRVTPVDQFVWSPHIELVGVFTR
HHHHHHHHHCCCCCCHHHHHHHHEEEECCCEEEEECCHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MQDLTINAIGAQGDGLARTADGKPAFVPLTLPGEVVRAKMDGARGEVVEILAPSPERVAP
CCCEEEEEECCCCCCCEEECCCCCEEEEEECCHHHHHHHCCCCCCCEEEEECCCCHHHHH
ACRHYGVCGGCALQHWAAEPYRAWKAEQVRLQLSMEGLETEILPTFAAPPASRRRVALHA
HHHHCCCCCCHHHHHHCCCHHHHCCCEEEEEEEEECCCCEEEEECCCCCCCCCCEEEEEE
RKGGKGQGARLGFKERRSWNLVSIEECPVTDPRLVAALPALARLAEPFLEHPKSAPTLHV
CCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TLTATGLDIDITGVERKSGGLSADARMRAAMAAGEGDFARVTLAGETIYGARQPLVKLGQ
EEEEECCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCC
AVVALPPGSFLQAVPAAEKAMVELAVAEAQGASRVADLYCGVGTFTFPLAEVAQVYAAEM
EEEEECCCHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHC
SAPAITALKAAIGGAPGLKPITAEARDLVRRPVLSTELAKTDVVVIDPPRAGAAEQTVEI
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCEEEECCCCCCCHHHHHHH
AKSKVAKVLGVSCNPQTFAKDARVLVDAGFKLVRVTPVDQFVWSPHIELVGVFTR
HHHHHHHHHCCCCCCHHHHHHHHEEEECCCEEEEECCHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647