Click here to switch to the map view.

The map label for this gene is pkn1 [H]

Identifier: 16125425

GI number: 16125425

Start: 1332762

End: 1333778

Strand: Direct

Name: pkn1 [H]

Synonym: CC_1173

Alternate gene names: 16125425

Gene position: 1332762-1333778 (Clockwise)

Preceding gene: 16125424

Following gene: 16125426

Centisome position: 33.18

GC content: 70.89

Gene sequence:

>1017_bases
TTGGGAAAACTGACGGCGCTTCCCGTCCTGATGCTTCTGGCGCTGGCCGGCTGCGGCCAGCCGGCGCCCAAGGCTTGCCT
GGCGGACCTGCCGGTTCCAGATCCCCAGAACCGCACGGCGGGTATGGTTCGGCTGGCGGGCGGCGACTTCCAGATGGGCG
CTGCGCCGCTGCGTCCGGAGGAGGGACCGCCCCAGACGGTCACGGTCCCGCCGTTCTGGATCGATCAGACAGAGGTCACC
AACGCCGCCTTCGCGCGGTTCGTCGAGGCCACGGGTTATCGCACCGTGGCCGAGCGACCGCTCGACCCCGCGCGCTACGC
CCACGTACCGGCGGCGCAGCGGCGTCCGGCCTCGCTCGTCTTCGTGGGGGCGAAGGGGGCGAGGTCGGACGATCCTTCCC
AATGGTGGCAGGTGATCCCCGGCGCCGACTGGCGGCATCCCGAAGGTCCCGGCTCGAACATCCGGGGCAGGGACGCCTGG
CCGGTGGTGCATATCGCGTGGGAGGACGCCATGGCCTACGCCCGCTGGCTGGGCCGTGACCTGCCCACAGAGGCCGAATG
GGAGTACGCCGCGCGCGGCGGGCTGGTTGGCAAGCGCTACACCTGGGGCGACCAGGCTCAGGATCCTGCAAAGCCGCGCG
CCAATACTTGGCAAGGCGTGTTCCCGGCCCAGGACCTTGGCAATGACGGCTTCAAGGCCAAGCCCGCGCCGGTCGGCTGC
TTCCCGCCCAACGGCTATGGCCTGCGCGACATGGCCGGCAATGTCTGGGAGTGGACCCGCGACTGGTTCAAGCCGGGCCT
GGATCCGGTCAGCGTCCTCGAAACCGGCGGGCCGCCCGAGGCCCGCGCGCTGGATCCCGAGGACCCGAACACGCCCAAGC
ACGTCGTGAAGGGCGGTTCGTTCCTGTGCGCCGACGACTACTGCTTCCGCTATCGACCTGCGGCGCGAACGCCGGGGCCG
CCGGACAGCGGCGCATCGCATGTCGGTTTCCGCACCGTGCTCCGCGCCGAGCGCTGA

Upstream 100 bases:

>100_bases
GACAGATGATGAAGCCGACCTGGCCGTCGCTGATTTCGGGCGCCTTCTATATCGACCATCCGGGCGGCCAGAAGGCCAAG
CCCAGCGACGAGTACATCTA

Downstream 100 bases:

>100_bases
GCGCTCAGTTCACTGCGTTGGCCTGTTCGGGCTTCCACAGGCGCTCGTCGTTGTGCACGCCGTGCGACTCGAAGCCCAGC
GCAGGCCGGGTCCTGATGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MGKLTALPVLMLLALAGCGQPAPKACLADLPVPDPQNRTAGMVRLAGGDFQMGAAPLRPEEGPPQTVTVPPFWIDQTEVT
NAAFARFVEATGYRTVAERPLDPARYAHVPAAQRRPASLVFVGAKGARSDDPSQWWQVIPGADWRHPEGPGSNIRGRDAW
PVVHIAWEDAMAYARWLGRDLPTEAEWEYAARGGLVGKRYTWGDQAQDPAKPRANTWQGVFPAQDLGNDGFKAKPAPVGC
FPPNGYGLRDMAGNVWEWTRDWFKPGLDPVSVLETGGPPEARALDPEDPNTPKHVVKGGSFLCADDYCFRYRPAARTPGP
PDSGASHVGFRTVLRAER

Sequences:

>Translated_338_residues
MGKLTALPVLMLLALAGCGQPAPKACLADLPVPDPQNRTAGMVRLAGGDFQMGAAPLRPEEGPPQTVTVPPFWIDQTEVT
NAAFARFVEATGYRTVAERPLDPARYAHVPAAQRRPASLVFVGAKGARSDDPSQWWQVIPGADWRHPEGPGSNIRGRDAW
PVVHIAWEDAMAYARWLGRDLPTEAEWEYAARGGLVGKRYTWGDQAQDPAKPRANTWQGVFPAQDLGNDGFKAKPAPVGC
FPPNGYGLRDMAGNVWEWTRDWFKPGLDPVSVLETGGPPEARALDPEDPNTPKHVVKGGSFLCADDYCFRYRPAARTPGP
PDSGASHVGFRTVLRAER
>Mature_337_residues
GKLTALPVLMLLALAGCGQPAPKACLADLPVPDPQNRTAGMVRLAGGDFQMGAAPLRPEEGPPQTVTVPPFWIDQTEVTN
AAFARFVEATGYRTVAERPLDPARYAHVPAAQRRPASLVFVGAKGARSDDPSQWWQVIPGADWRHPEGPGSNIRGRDAWP
VVHIAWEDAMAYARWLGRDLPTEAEWEYAARGGLVGKRYTWGDQAQDPAKPRANTWQGVFPAQDLGNDGFKAKPAPVGCF
PPNGYGLRDMAGNVWEWTRDWFKPGLDPVSVLETGGPPEARALDPEDPNTPKHVVKGGSFLCADDYCFRYRPAARTPGPP
DSGASHVGFRTVLRAER

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=310, Percent_Identity=41.6129032258065, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI257470975, Length=313, Percent_Identity=40.2555910543131, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI257470977, Length=310, Percent_Identity=40, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI194248088, Length=302, Percent_Identity=38.7417218543046, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI194248087, Length=302, Percent_Identity=37.0860927152318, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI194248090, Length=209, Percent_Identity=43.0622009569378, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226437577, Length=207, Percent_Identity=41.5458937198068, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20130397, Length=303, Percent_Identity=38.6138613861386, Blast_Score=191, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 36748; Mature: 36616

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLTALPVLMLLALAGCGQPAPKACLADLPVPDPQNRTAGMVRLAGGDFQMGAAPLRPE
CCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
EGPPQTVTVPPFWIDQTEVTNAAFARFVEATGYRTVAERPLDPARYAHVPAAQRRPASLV
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCCCCCCCCCCEEE
FVGAKGARSDDPSQWWQVIPGADWRHPEGPGSNIRGRDAWPVVHIAWEDAMAYARWLGRD
EEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCC
LPTEAEWEYAARGGLVGKRYTWGDQAQDPAKPRANTWQGVFPAQDLGNDGFKAKPAPVGC
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
FPPNGYGLRDMAGNVWEWTRDWFKPGLDPVSVLETGGPPEARALDPEDPNTPKHVVKGGS
CCCCCCCHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCC
FLCADDYCFRYRPAARTPGPPDSGASHVGFRTVLRAER
EEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
GKLTALPVLMLLALAGCGQPAPKACLADLPVPDPQNRTAGMVRLAGGDFQMGAAPLRPE
CCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
EGPPQTVTVPPFWIDQTEVTNAAFARFVEATGYRTVAERPLDPARYAHVPAAQRRPASLV
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCCCCCCCCCCEEE
FVGAKGARSDDPSQWWQVIPGADWRHPEGPGSNIRGRDAWPVVHIAWEDAMAYARWLGRD
EEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCC
LPTEAEWEYAARGGLVGKRYTWGDQAQDPAKPRANTWQGVFPAQDLGNDGFKAKPAPVGC
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
FPPNGYGLRDMAGNVWEWTRDWFKPGLDPVSVLETGGPPEARALDPEDPNTPKHVVKGGS
CCCCCCCHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCC
FLCADDYCFRYRPAARTPGPPDSGASHVGFRTVLRAER
EEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]