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The map label for this gene is ydeN [H]

Identifier: 16125424

GI number: 16125424

Start: 1331209

End: 1332774

Strand: Direct

Name: ydeN [H]

Synonym: CC_1172

Alternate gene names: 16125424

Gene position: 1331209-1332774 (Clockwise)

Preceding gene: 16125422

Following gene: 16125425

Centisome position: 33.14

GC content: 65.39

Gene sequence:

>1566_bases
ATGCTGGCCAAGGCCCGGCAGCCGAAGATCGAAGCCAATATGCCGGTGACCTGGGCCAAGGGCCCGCAAGCGCCGCCGGC
GGACGGTCAGCGGCCGCCCAATATCGTGTTCATTCTCGCCGACGACCTCGGCTACAACGACATTACGCTGAATGGCGGCG
GCGTCGCGGGCGGCACAGTACCCACGCCCGCCATCGACTCGATCGCCAAGGAGGGGGTCACCTTCGCCAACGGCTACAGC
GGCAACGCCACCTGCGCGCCCTCGCGCGCGGCGATCATGACCGGCCGCTATGCCACGCGCTTTGGCTTTGAGTTCACCCC
AACGCCCGTGGCCTTCTCACGCGTGGTCGGCGGCCATGCCGGCGATCCTCTGCACCCCTCGCGCTTCAATCAAGCCGAGG
TGAAGAACATGCCCAAGGACGAGAACGTCCTGGCCGTGCCCGCCGCCGAGGTGACGATCGCCGAGGCGCTCAAGACCAAG
GGCTATCACACCATTCACCTGGGCAAGTGGCATCTGGGCGGCGTCAAAGGTTCGCGCCCGGAGGATCAGGGTTTTGACGA
AAGCCTCGGCTTCATGGCGGGCGCCGCGCTGTTCGCGCCGGTCGGGGACCCCGGCGTGGTGGAGTCGCGCCAGGACTGGG
ATCCGATCGACAAGTTCCTCTGGGGCGCAGCGCCGTTCGCCGTGCAGTTCAACGGCGGCAAGCTGTTCAATCCCAGCCAC
TACATGACCGACTACCTGACAGACGAAGCGGTGAAGGCGATCGACGCCAACAAGAACCGGCCGTTCTTCATGTATCTGGC
CTACAACGCCGTCCACACGCCGTTGCAGGCGCCCAAGGCCGACTATGATGCGCTGTCGCACATCAAGGATCACCGGATGC
GCGTCTATGCAGCCATGGTCCGCAACCTCGACCGCAACGTCGGCAAGGTGCTGCAGGCGCTGAAGGACCGGGGGCTGGAC
GACAACACCCTGGTGATCTTCACCTCGGACAACGGCGGCGCGAACTACATTGGCCTGCCGGACATCAACAAGCCCTATCG
CGGCTGGAAGGCGACCTTCTTCGAGGGCGGGATCAAGGTGCCGTTCCTGCTGCGTTGGCCCGAGCAGCTGCCGGCCGGCG
CAGTCTATCGCAGCCCGGTGGGCCATGTGGACATCTTCGCCACGGCCGCCGGCGCCGCCGGTGCGCCCACACCCAAGGAT
CGGGTGCTGGACGGCGTCGACCTCGTGCCGTTCGTGAAGGGACAGTCCTCGGGCGATCCGCACAAGGCGATCTTCTGGCG
TTCGGGCGGCTACAAGACGGTGCTCGCAGGCGGCTGGAAGCTGCAGGTGGCCAAGGAGCCAAACAAGACCTGGCTCTTTG
ACCTGTCCACCGATCCGACCGAGCGCCAGGAGCTGTCCAAGGCGCGGCCCGAGAAGCTGCGTGAGATGCAGGCGATCATG
GCGCAGCTGGACGGACAGATGATGAAGCCGACCTGGCCGTCGCTGATTTCGGGCGCCTTCTATATCGACCATCCGGGCGG
CCAGAAGGCCAAGCCCAGCGACGAGTACATCTATTGGGAAAACTGA

Upstream 100 bases:

>100_bases
GGAGGCGCGCATGAAGGCCTGGAAGCCGCTTGTCGCGGGTGTGGCGGTTCTCGCTGTCGCGGGCGCGACGGCCTGGCATT
TCCGTTTCGACCTGATCGTG

Downstream 100 bases:

>100_bases
CGGCGCTTCCCGTCCTGATGCTTCTGGCGCTGGCCGGCTGCGGCCAGCCGGCGCCCAAGGCTTGCCTGGCGGACCTGCCG
GTTCCAGATCCCCAGAACCG

Product: sulfatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MLAKARQPKIEANMPVTWAKGPQAPPADGQRPPNIVFILADDLGYNDITLNGGGVAGGTVPTPAIDSIAKEGVTFANGYS
GNATCAPSRAAIMTGRYATRFGFEFTPTPVAFSRVVGGHAGDPLHPSRFNQAEVKNMPKDENVLAVPAAEVTIAEALKTK
GYHTIHLGKWHLGGVKGSRPEDQGFDESLGFMAGAALFAPVGDPGVVESRQDWDPIDKFLWGAAPFAVQFNGGKLFNPSH
YMTDYLTDEAVKAIDANKNRPFFMYLAYNAVHTPLQAPKADYDALSHIKDHRMRVYAAMVRNLDRNVGKVLQALKDRGLD
DNTLVIFTSDNGGANYIGLPDINKPYRGWKATFFEGGIKVPFLLRWPEQLPAGAVYRSPVGHVDIFATAAGAAGAPTPKD
RVLDGVDLVPFVKGQSSGDPHKAIFWRSGGYKTVLAGGWKLQVAKEPNKTWLFDLSTDPTERQELSKARPEKLREMQAIM
AQLDGQMMKPTWPSLISGAFYIDHPGGQKAKPSDEYIYWEN

Sequences:

>Translated_521_residues
MLAKARQPKIEANMPVTWAKGPQAPPADGQRPPNIVFILADDLGYNDITLNGGGVAGGTVPTPAIDSIAKEGVTFANGYS
GNATCAPSRAAIMTGRYATRFGFEFTPTPVAFSRVVGGHAGDPLHPSRFNQAEVKNMPKDENVLAVPAAEVTIAEALKTK
GYHTIHLGKWHLGGVKGSRPEDQGFDESLGFMAGAALFAPVGDPGVVESRQDWDPIDKFLWGAAPFAVQFNGGKLFNPSH
YMTDYLTDEAVKAIDANKNRPFFMYLAYNAVHTPLQAPKADYDALSHIKDHRMRVYAAMVRNLDRNVGKVLQALKDRGLD
DNTLVIFTSDNGGANYIGLPDINKPYRGWKATFFEGGIKVPFLLRWPEQLPAGAVYRSPVGHVDIFATAAGAAGAPTPKD
RVLDGVDLVPFVKGQSSGDPHKAIFWRSGGYKTVLAGGWKLQVAKEPNKTWLFDLSTDPTERQELSKARPEKLREMQAIM
AQLDGQMMKPTWPSLISGAFYIDHPGGQKAKPSDEYIYWEN
>Mature_521_residues
MLAKARQPKIEANMPVTWAKGPQAPPADGQRPPNIVFILADDLGYNDITLNGGGVAGGTVPTPAIDSIAKEGVTFANGYS
GNATCAPSRAAIMTGRYATRFGFEFTPTPVAFSRVVGGHAGDPLHPSRFNQAEVKNMPKDENVLAVPAAEVTIAEALKTK
GYHTIHLGKWHLGGVKGSRPEDQGFDESLGFMAGAALFAPVGDPGVVESRQDWDPIDKFLWGAAPFAVQFNGGKLFNPSH
YMTDYLTDEAVKAIDANKNRPFFMYLAYNAVHTPLQAPKADYDALSHIKDHRMRVYAAMVRNLDRNVGKVLQALKDRGLD
DNTLVIFTSDNGGANYIGLPDINKPYRGWKATFFEGGIKVPFLLRWPEQLPAGAVYRSPVGHVDIFATAAGAAGAPTPKD
RVLDGVDLVPFVKGQSSGDPHKAIFWRSGGYKTVLAGGWKLQVAKEPNKTWLFDLSTDPTERQELSKARPEKLREMQAIM
AQLDGQMMKPTWPSLISGAFYIDHPGGQKAKPSDEYIYWEN

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=503, Percent_Identity=30.6163021868787, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI59797060, Length=514, Percent_Identity=27.2373540856031, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI38569405, Length=517, Percent_Identity=29.2069632495164, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI38569407, Length=409, Percent_Identity=32.0293398533007, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI31742482, Length=564, Percent_Identity=26.9503546099291, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI53831991, Length=534, Percent_Identity=28.6516853932584, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI109389362, Length=513, Percent_Identity=27.0955165692008, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI157266309, Length=484, Percent_Identity=28.3057851239669, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI146229331, Length=479, Percent_Identity=28.6012526096033, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI146229329, Length=479, Percent_Identity=28.6012526096033, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI6005990, Length=479, Percent_Identity=28.6012526096033, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI146229324, Length=479, Percent_Identity=28.6012526096033, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI45430057, Length=429, Percent_Identity=28.9044289044289, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI71852584, Length=194, Percent_Identity=32.9896907216495, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI146229327, Length=364, Percent_Identity=28.2967032967033, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI58743319, Length=194, Percent_Identity=32.9896907216495, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI71852586, Length=165, Percent_Identity=32.7272727272727, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI87081924, Length=525, Percent_Identity=27.4285714285714, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI1790233, Length=421, Percent_Identity=29.9287410926366, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI115533416, Length=494, Percent_Identity=29.9595141700405, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI115533418, Length=479, Percent_Identity=29.4363256784969, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17559078, Length=258, Percent_Identity=29.0697674418605, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24666175, Length=402, Percent_Identity=32.3383084577114, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281363223, Length=382, Percent_Identity=32.1989528795811, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24666109, Length=406, Percent_Identity=31.7733990147783, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI281366397, Length=401, Percent_Identity=29.6758104738155, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI281366395, Length=401, Percent_Identity=29.6758104738155, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24666163, Length=401, Percent_Identity=29.6758104738155, Blast_Score=155, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 56710; Mature: 56710

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKARQPKIEANMPVTWAKGPQAPPADGQRPPNIVFILADDLGYNDITLNGGGVAGGTV
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCC
PTPAIDSIAKEGVTFANGYSGNATCAPSRAAIMTGRYATRFGFEFTPTPVAFSRVVGGHA
CCHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCHHHCCCEECCCCHHHHHHHCCCC
GDPLHPSRFNQAEVKNMPKDENVLAVPAAEVTIAEALKTKGYHTIHLGKWHLGGVKGSRP
CCCCCCCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCEEEEEECCEEECCCCCCCC
EDQGFDESLGFMAGAALFAPVGDPGVVESRQDWDPIDKFLWGAAPFAVQFNGGKLFNPSH
CCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCEEECCHH
YMTDYLTDEAVKAIDANKNRPFFMYLAYNAVHTPLQAPKADYDALSHIKDHRMRVYAAMV
HHHHHHHHHHHHHHCCCCCCCEEEEEEECHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RNLDRNVGKVLQALKDRGLDDNTLVIFTSDNGGANYIGLPDINKPYRGWKATFFEGGIKV
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEEEECCCCCC
PFLLRWPEQLPAGAVYRSPVGHVDIFATAAGAAGAPTPKDRVLDGVDLVPFVKGQSSGDP
EEEEECHHHCCCCCEECCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCEEEECCCCCCCC
HKAIFWRSGGYKTVLAGGWKLQVAKEPNKTWLFDLSTDPTERQELSKARPEKLREMQAIM
CEEEEEECCCEEEEEECCEEEEEEECCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHH
AQLDGQMMKPTWPSLISGAFYIDHPGGQKAKPSDEYIYWEN
HHHCCCCCCCCCHHHHCCEEEEECCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MLAKARQPKIEANMPVTWAKGPQAPPADGQRPPNIVFILADDLGYNDITLNGGGVAGGTV
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCC
PTPAIDSIAKEGVTFANGYSGNATCAPSRAAIMTGRYATRFGFEFTPTPVAFSRVVGGHA
CCHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCHHHCCCEECCCCHHHHHHHCCCC
GDPLHPSRFNQAEVKNMPKDENVLAVPAAEVTIAEALKTKGYHTIHLGKWHLGGVKGSRP
CCCCCCCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCEEEEEECCEEECCCCCCCC
EDQGFDESLGFMAGAALFAPVGDPGVVESRQDWDPIDKFLWGAAPFAVQFNGGKLFNPSH
CCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCEEECCHH
YMTDYLTDEAVKAIDANKNRPFFMYLAYNAVHTPLQAPKADYDALSHIKDHRMRVYAAMV
HHHHHHHHHHHHHHCCCCCCCEEEEEEECHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RNLDRNVGKVLQALKDRGLDDNTLVIFTSDNGGANYIGLPDINKPYRGWKATFFEGGIKV
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEEEECCCCCC
PFLLRWPEQLPAGAVYRSPVGHVDIFATAAGAAGAPTPKDRVLDGVDLVPFVKGQSSGDP
EEEEECHHHCCCCCEECCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCEEEECCCCCCCC
HKAIFWRSGGYKTVLAGGWKLQVAKEPNKTWLFDLSTDPTERQELSKARPEKLREMQAIM
CEEEEEECCCEEEEEECCEEEEEEECCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHH
AQLDGQMMKPTWPSLISGAFYIDHPGGQKAKPSDEYIYWEN
HHHCCCCCCCCCHHHHCCEEEEECCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]