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The map label for this gene is cysH [H]

Identifier: 16125373

GI number: 16125373

Start: 1272170

End: 1272904

Strand: Direct

Name: cysH [H]

Synonym: CC_1121

Alternate gene names: 16125373

Gene position: 1272170-1272904 (Clockwise)

Preceding gene: 16125372

Following gene: 16125375

Centisome position: 31.67

GC content: 68.44

Gene sequence:

>735_bases
GTGGCCTACGACCAGACGAGCGCGACGGCTCCAGGCCTTGCCGCCCGGCTGGACGCCGAGCTGCGCGACGCCCATCCCAG
CGAGATCCTCCGCACGGCCCATGAGCACTTCGGCGACAAGCTGGCGCTGGTGTCGTCGTTCGGCGCCGAGTCGGCGGTGC
TGCTGCATCTGGCCTCGCGCGTCTCGCCGGGCCTGCCGGTTCTGTTCCTCGACACCGGGATGCTGTTTGGCCAGACGCTG
GACTATCGAAAGAATATCGCGGCCCAGTTCGGCCTGACCGATGTCCGCGATCTGCGGCCGGCTTTCGCGGACCTGGCGAC
CCAGGACCCTAACTCCGACCTCTGGCGCACCAGCGTCGACGGCTGCTGCCACATTCGCAAGGTTCTGCCGCTGGATCGCG
CGTTGGGCGGCTTCGACGCCTGGATCACCGGTCGCAAGCGCTTCCACGGCGGTGATCGCCTGAGCCTGCCAGTGGTCGAA
GAGGCCGACGGCAAGATCAAGTTCAACCCGTTGGCCAACTGGTCCAAGGCCGAGCTCGACGCCTATGTCGCCGAACATGA
CCTGCCGGCCCACCCGCTGGTGGCCCAGGGCTATGCCTCGGTCGGCTGTTGGCCGTGCACGCAGCCTTCCGACGACGGAA
GGTCCGGGCGCTGGGCGGGTCAGGAAAAGACCGAGTGCGGCATCCACGTCGCGCGGGCGCCCGGTGTCGCGCCGAACGTG
GGCGGGGATATCTGA

Upstream 100 bases:

>100_bases
CGACGCCCGAGGTGCTGACCAAGGCCGCCAATCGGTTCCGGCATGTCTATCAGCGCGCGGCCGACGATCGCCCGATCGCG
CTGGATGAGAGGGCGGTCTA

Downstream 100 bases:

>100_bases
TCTAAATCCTCCCCCTAGCGGGGGAGATGGCGCGAAGCGCCGGAGGGGGAAGAGCCTGATGCCCTGCCTCTTCCCCCTCC
GTCGTCTCTTCGAGCCGACA

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAYDQTSATAPGLAARLDAELRDAHPSEILRTAHEHFGDKLALVSSFGAESAVLLHLASRVSPGLPVLFLDTGMLFGQTL
DYRKNIAAQFGLTDVRDLRPAFADLATQDPNSDLWRTSVDGCCHIRKVLPLDRALGGFDAWITGRKRFHGGDRLSLPVVE
EADGKIKFNPLANWSKAELDAYVAEHDLPAHPLVAQGYASVGCWPCTQPSDDGRSGRWAGQEKTECGIHVARAPGVAPNV
GGDI

Sequences:

>Translated_244_residues
MAYDQTSATAPGLAARLDAELRDAHPSEILRTAHEHFGDKLALVSSFGAESAVLLHLASRVSPGLPVLFLDTGMLFGQTL
DYRKNIAAQFGLTDVRDLRPAFADLATQDPNSDLWRTSVDGCCHIRKVLPLDRALGGFDAWITGRKRFHGGDRLSLPVVE
EADGKIKFNPLANWSKAELDAYVAEHDLPAHPLVAQGYASVGCWPCTQPSDDGRSGRWAGQEKTECGIHVARAPGVAPNV
GGDI
>Mature_243_residues
AYDQTSATAPGLAARLDAELRDAHPSEILRTAHEHFGDKLALVSSFGAESAVLLHLASRVSPGLPVLFLDTGMLFGQTLD
YRKNIAAQFGLTDVRDLRPAFADLATQDPNSDLWRTSVDGCCHIRKVLPLDRALGGFDAWITGRKRFHGGDRLSLPVVEE
ADGKIKFNPLANWSKAELDAYVAEHDLPAHPLVAQGYASVGCWPCTQPSDDGRSGRWAGQEKTECGIHVARAPGVAPNVG
GDI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=223, Percent_Identity=31.390134529148, Blast_Score=101, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325425, Length=208, Percent_Identity=32.2115384615385, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26277; Mature: 26146

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYDQTSATAPGLAARLDAELRDAHPSEILRTAHEHFGDKLALVSSFGAESAVLLHLASR
CCCCCCCCCCCCHHHHHCHHHHCCCHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHHH
VSPGLPVLFLDTGMLFGQTLDYRKNIAAQFGLTDVRDLRPAFADLATQDPNSDLWRTSVD
CCCCCCEEEEECCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCHH
GCCHIRKVLPLDRALGGFDAWITGRKRFHGGDRLSLPVVEEADGKIKFNPLANWSKAELD
HHHHHHHHHHHHHHHCCHHHHCCCCHHCCCCCEECCCEEECCCCEEEECCCCCCCHHHHH
AYVAEHDLPAHPLVAQGYASVGCWPCTQPSDDGRSGRWAGQEKTECGIHVARAPGVAPNV
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GGDI
CCCC
>Mature Secondary Structure 
AYDQTSATAPGLAARLDAELRDAHPSEILRTAHEHFGDKLALVSSFGAESAVLLHLASR
CCCCCCCCCCCHHHHHCHHHHCCCHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHHH
VSPGLPVLFLDTGMLFGQTLDYRKNIAAQFGLTDVRDLRPAFADLATQDPNSDLWRTSVD
CCCCCCEEEEECCHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCHH
GCCHIRKVLPLDRALGGFDAWITGRKRFHGGDRLSLPVVEEADGKIKFNPLANWSKAELD
HHHHHHHHHHHHHHHCCHHHHCCCCHHCCCCCEECCCEEECCCCEEEECCCCCCCHHHHH
AYVAEHDLPAHPLVAQGYASVGCWPCTQPSDDGRSGRWAGQEKTECGIHVARAPGVAPNV
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GGDI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]