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The map label for this gene is glsA

Identifier: 16124531

GI number: 16124531

Start: 291339

End: 292259

Strand: Direct

Name: glsA

Synonym: CC_0276

Alternate gene names: 16124531

Gene position: 291339-292259 (Clockwise)

Preceding gene: 16124530

Following gene: 16124532

Centisome position: 7.25

GC content: 69.16

Gene sequence:

>921_bases
ATGAAGGCGCTCTCGATCCCCGATGTGCTGGCCGAGGTGGCGGTGCTGGTCAGGCCGCACTTCGGCAAAGGCAAGCCCGC
CGACTACATCCCGCAACTGGCCACCGTGCCCGGCGGCAAGTTCGGCATGGCCGTGCGCATGGTCGATGGCGATGAGCATG
TCATTGGCGACGCCGATGAGGGCTTTTCGGTCCAGAGCATCACCAAGGTCTTCGCCCTGGGCCTGGCCCTGAACCGGCTG
GGCGATGAGATCTGGACCCGGGTGGGCAAGGAGCCCTCGGGCACGCCGTTCAACCACCTGTCCCTGCTGGAAGCCGAGCA
GGGCGTGCCGCGCAACCCGTTCATCAACGCCGGCGCCCTGGCGGTGACCGACGTGCTGATGGACGTCACGCGCGACCCGG
CGGCCCTGGTCCGCGACTTTGGCGGCTTCCTGTGCGGGGAGCGTTTGGAGATCGACCCGGCGGTGGCGACCTCGGAGCTG
GCCCATGCCTGGCAGAACCGCGCCATCGCCAGCCTGATGCGCGCCAAGGGCACCATCACCCACGACCCGGAGGCGGTGGT
GGCCGCCTATTGCCGCCAGTGCGCCCTCTCCATGAGCTGCCGCCAGCTGGCGCGCGCCTTCCTGCCGCTGGCGGCCGGCG
GCTTTTCGCCGATCGCGCAGGAGACGGTGTTCCCCGAGCGCCTGACGCGGCGCCTCAACGCCCTGCTGCTGACCTGCGGC
ATCTATGACAGCGTCGGCAGCTTCGCCTATCGCGTGGGGTTGCCGGCCAAGAGCGGGGTGGGCGGGGGGATCGTAGCGGT
GGTCCCGGGTAAGGCGACGGTGGCGGTGTGGTCGCCGGAGCTTGACCGGTTCGGCACGTCCGTCGTCGGAACCGCCGCCC
TGGAAGCGTTCAGCCAGATCACCAACTGTTCGGTATTGTAG

Upstream 100 bases:

>100_bases
AGCGGGTCCCGGTCGAGGAGGTTCGCCAGCTGGCGGGCGCCTATGAGGCGCTGATCCGCCGCTACTTCGCAGCATTCGCC
TAAGCCGCGCGGGGACGAGG

Downstream 100 bases:

>100_bases
CGTTGATCAGGATCAACGCGCGCTGGCGTCGGCCGGCGCAGGCTGCGGCTCATGACCACGCCAAGCCGTCGCATCCTGAT
CTTGGTCGGCCATCCCGACC

Product: glutaminase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKALSIPDVLAEVAVLVRPHFGKGKPADYIPQLATVPGGKFGMAVRMVDGDEHVIGDADEGFSVQSITKVFALGLALNRL
GDEIWTRVGKEPSGTPFNHLSLLEAEQGVPRNPFINAGALAVTDVLMDVTRDPAALVRDFGGFLCGERLEIDPAVATSEL
AHAWQNRAIASLMRAKGTITHDPEAVVAAYCRQCALSMSCRQLARAFLPLAAGGFSPIAQETVFPERLTRRLNALLLTCG
IYDSVGSFAYRVGLPAKSGVGGGIVAVVPGKATVAVWSPELDRFGTSVVGTAALEAFSQITNCSVL

Sequences:

>Translated_306_residues
MKALSIPDVLAEVAVLVRPHFGKGKPADYIPQLATVPGGKFGMAVRMVDGDEHVIGDADEGFSVQSITKVFALGLALNRL
GDEIWTRVGKEPSGTPFNHLSLLEAEQGVPRNPFINAGALAVTDVLMDVTRDPAALVRDFGGFLCGERLEIDPAVATSEL
AHAWQNRAIASLMRAKGTITHDPEAVVAAYCRQCALSMSCRQLARAFLPLAAGGFSPIAQETVFPERLTRRLNALLLTCG
IYDSVGSFAYRVGLPAKSGVGGGIVAVVPGKATVAVWSPELDRFGTSVVGTAALEAFSQITNCSVL
>Mature_306_residues
MKALSIPDVLAEVAVLVRPHFGKGKPADYIPQLATVPGGKFGMAVRMVDGDEHVIGDADEGFSVQSITKVFALGLALNRL
GDEIWTRVGKEPSGTPFNHLSLLEAEQGVPRNPFINAGALAVTDVLMDVTRDPAALVRDFGGFLCGERLEIDPAVATSEL
AHAWQNRAIASLMRAKGTITHDPEAVVAAYCRQCALSMSCRQLARAFLPLAAGGFSPIAQETVFPERLTRRLNALLLTCG
IYDSVGSFAYRVGLPAKSGVGGGIVAVVPGKATVAVWSPELDRFGTSVVGTAALEAFSQITNCSVL

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=273, Percent_Identity=38.8278388278388, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI20336214, Length=285, Percent_Identity=34.7368421052632, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1787804, Length=299, Percent_Identity=49.1638795986622, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1786693, Length=269, Percent_Identity=38.6617100371747, Blast_Score=174, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17507019, Length=315, Percent_Identity=34.9206349206349, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17532727, Length=277, Percent_Identity=33.9350180505415, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193204075, Length=283, Percent_Identity=32.1554770318021, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193204073, Length=281, Percent_Identity=32.0284697508897, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281363241, Length=290, Percent_Identity=35.8620689655172, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24653164, Length=290, Percent_Identity=35.8620689655172, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24653162, Length=290, Percent_Identity=35.8620689655172, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI281363239, Length=290, Percent_Identity=35.8620689655172, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24653158, Length=290, Percent_Identity=35.8620689655172, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24653156, Length=290, Percent_Identity=35.8620689655172, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI116008307, Length=290, Percent_Identity=35.8620689655172, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24653166, Length=290, Percent_Identity=35.8620689655172, Blast_Score=164, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_CAUCN (B8GYE8)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002515653.1
- ProteinModelPortal:   B8GYE8
- SMR:   B8GYE8
- GeneID:   7330731
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_00278
- OMA:   NALMLTC
- ProtClustDB:   PRK00971
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 32287; Mature: 32287

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALSIPDVLAEVAVLVRPHFGKGKPADYIPQLATVPGGKFGMAVRMVDGDEHVIGDADE
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCHHHCCCCCCCCEEEEEECCCCCEECCCCC
GFSVQSITKVFALGLALNRLGDEIWTRVGKEPSGTPFNHLSLLEAEQGVPRNPFINAGAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHH
AVTDVLMDVTRDPAALVRDFGGFLCGERLEIDPAVATSELAHAWQNRAIASLMRAKGTIT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HDPEAVVAAYCRQCALSMSCRQLARAFLPLAAGGFSPIAQETVFPERLTRRLNALLLTCG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHH
IYDSVGSFAYRVGLPAKSGVGGGIVAVVPGKATVAVWSPELDRFGTSVVGTAALEAFSQI
HHHHHHHHHEEECCCCCCCCCCCEEEEECCCEEEEEECCCHHHHCCHHHHHHHHHHHHHH
TNCSVL
HCCCCC
>Mature Secondary Structure
MKALSIPDVLAEVAVLVRPHFGKGKPADYIPQLATVPGGKFGMAVRMVDGDEHVIGDADE
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCHHHCCCCCCCCEEEEEECCCCCEECCCCC
GFSVQSITKVFALGLALNRLGDEIWTRVGKEPSGTPFNHLSLLEAEQGVPRNPFINAGAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHH
AVTDVLMDVTRDPAALVRDFGGFLCGERLEIDPAVATSELAHAWQNRAIASLMRAKGTIT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HDPEAVVAAYCRQCALSMSCRQLARAFLPLAAGGFSPIAQETVFPERLTRRLNALLLTCG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHH
IYDSVGSFAYRVGLPAKSGVGGGIVAVVPGKATVAVWSPELDRFGTSVVGTAALEAFSQI
HHHHHHHHHEEECCCCCCCCCCCEEEEECCCEEEEEECCCHHHHCCHHHHHHHHHHHHHH
TNCSVL
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA