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The map label for this gene is hutI [H]

Identifier: 13488311

GI number: 13488311

Start: 333080

End: 334399

Strand: Direct

Name: hutI [H]

Synonym: mlr9376

Alternate gene names: 13488311

Gene position: 333080-334399 (Clockwise)

Preceding gene: 13488310

Following gene: 13488312

Centisome position: 94.65

GC content: 59.47

Gene sequence:

>1320_bases
TTGCCCAATAACCCCACCACGTCGACCAGCGCCACTTCCGGCCCGAATTCCAATCTTCGGAAGGGCGAGGCTGGCGGGCT
GCTGATCACGAACATTGCGGAACTAACACCCCTCGATGAATTCGGGCCGGGTCCTCAGAGAGGTGGCCTGAAACACCTAA
AGTCGATCAGGAACGCTGCAATCCATGTCGTTGACGGACGGATAAGGGATTTTGGGCCTGCCGAACGAGTGGCGGTCGGA
TTGCCGAAGGGAGCAGAGCCTAGAGTTCTTGATGCAGCCGGAGGCGCGGTGGTACCTGGTTTCGTCGACTGCCATACCCA
CCTGCTCTATAGCGGTTCGCGGGCCGACGAGTACCCAATGCGGGTCGCGGGCGCTAGTTATGGCGAAATTAGTTCCAGGG
GCGGCGGCGTCACCCGCACAATTCGCGAAAGCAGTGACGCAACCTCAAGCGAACTCAAGCAGGCGTTGACGGTACGGCTG
GCGAAGGCGTTGCTGAATGGGACAACGACTGCGGAGATCAAAACCGGTTACTGGGTCGACCCGGAAGGAGAAGGCGCGGC
GCTGGGTATCATCGCCGAAGTCTCAGCGTCTCAGCCAGTCGATCTCGTTCAGACGTTCCATGTCGCGTTGGGCACGCCGG
CACGATTTGGTGGAGCTGGGGAATATGCCAGATACGTCATCGACTACGTTCTACCGTCCGTTGCCTCCCATGCACGCTTC
TGCGACGTCGTTTGCGATGTCGGGGCCTTCTCGCACGATGAGGCGCGGCAAATATTGCACGCAGCGGGCAGGCGCGGTTT
AAACTTCAAGATTCACGCCGATGAATTTTCCGCCGCCGGCGGTGCCGAACTCGCAGCTGAGCTTGGCGCTGTTTCAGCCG
ATCATTTATGCTTCCTGGGAAAAGACACTGCCCAAACGCTGGCCAAGGCACAAACGGTTGCCGTCTTGCTTCCGGCGACG
TGTCACTATCTGCTTGCTCCCAAGTTCGCGGACGCCCGCCACCTCATTGACGGCGGAGTAGCGATAGCGCTCGGGACAGA
TCATGGGCCAGGCAGTCCGACCCTTTCAATGCCGTTCGTCATGGGTCTGGCATGTTCCTGGTTGCGAATGGATCCGGCCG
AGGCGCTGGTCGCGGCGACGTGTAACGCCGCCCACGCCATCGGAGCCGCCTCAACTGCGGGCCAAATAGCGATCGGGCGC
CCAGCGGACCTGGTGGTCCTAAAGACGCCGACCTATCGAGATCTAGCATATTTGATCGACCAAAACTTGATCCGATACAC
CCTTAAGGACGGCGCTGTCTTCGGCAAGCACATAAAATAA

Upstream 100 bases:

>100_bases
CACATGCTCGTCAATGCCAACGGCATCTCCTTCAGCGAGACTATTCTGGTGACGGAAACGGGTTCGGAACGCCTGACTTC
CCTGCCGCGGGAGCTGTACA

Downstream 100 bases:

>100_bases
CAACTTCAACAAAGGGGAATAAAGTGGCCGTGCTGCTGCCCGTAACCCACCACTACAAATTGGCTCGTAAGCTGCCTGAC
AGGCGAACGCTGATCGAGGA

Product: hydrolase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MPNNPTTSTSATSGPNSNLRKGEAGGLLITNIAELTPLDEFGPGPQRGGLKHLKSIRNAAIHVVDGRIRDFGPAERVAVG
LPKGAEPRVLDAAGGAVVPGFVDCHTHLLYSGSRADEYPMRVAGASYGEISSRGGGVTRTIRESSDATSSELKQALTVRL
AKALLNGTTTAEIKTGYWVDPEGEGAALGIIAEVSASQPVDLVQTFHVALGTPARFGGAGEYARYVIDYVLPSVASHARF
CDVVCDVGAFSHDEARQILHAAGRRGLNFKIHADEFSAAGGAELAAELGAVSADHLCFLGKDTAQTLAKAQTVAVLLPAT
CHYLLAPKFADARHLIDGGVAIALGTDHGPGSPTLSMPFVMGLACSWLRMDPAEALVAATCNAAHAIGAASTAGQIAIGR
PADLVVLKTPTYRDLAYLIDQNLIRYTLKDGAVFGKHIK

Sequences:

>Translated_439_residues
MPNNPTTSTSATSGPNSNLRKGEAGGLLITNIAELTPLDEFGPGPQRGGLKHLKSIRNAAIHVVDGRIRDFGPAERVAVG
LPKGAEPRVLDAAGGAVVPGFVDCHTHLLYSGSRADEYPMRVAGASYGEISSRGGGVTRTIRESSDATSSELKQALTVRL
AKALLNGTTTAEIKTGYWVDPEGEGAALGIIAEVSASQPVDLVQTFHVALGTPARFGGAGEYARYVIDYVLPSVASHARF
CDVVCDVGAFSHDEARQILHAAGRRGLNFKIHADEFSAAGGAELAAELGAVSADHLCFLGKDTAQTLAKAQTVAVLLPAT
CHYLLAPKFADARHLIDGGVAIALGTDHGPGSPTLSMPFVMGLACSWLRMDPAEALVAATCNAAHAIGAASTAGQIAIGR
PADLVVLKTPTYRDLAYLIDQNLIRYTLKDGAVFGKHIK
>Mature_438_residues
PNNPTTSTSATSGPNSNLRKGEAGGLLITNIAELTPLDEFGPGPQRGGLKHLKSIRNAAIHVVDGRIRDFGPAERVAVGL
PKGAEPRVLDAAGGAVVPGFVDCHTHLLYSGSRADEYPMRVAGASYGEISSRGGGVTRTIRESSDATSSELKQALTVRLA
KALLNGTTTAEIKTGYWVDPEGEGAALGIIAEVSASQPVDLVQTFHVALGTPARFGGAGEYARYVIDYVLPSVASHARFC
DVVCDVGAFSHDEARQILHAAGRRGLNFKIHADEFSAAGGAELAAELGAVSADHLCFLGKDTAQTLAKAQTVAVLLPATC
HYLLAPKFADARHLIDGGVAIALGTDHGPGSPTLSMPFVMGLACSWLRMDPAEALVAATCNAAHAIGAASTAGQIAIGRP
ADLVVLKTPTYRDLAYLIDQNLIRYTLKDGAVFGKHIK

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=400, Percent_Identity=35, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17555004, Length=446, Percent_Identity=31.8385650224215, Blast_Score=217, Evalue=9e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 45701; Mature: 45570

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNPTTSTSATSGPNSNLRKGEAGGLLITNIAELTPLDEFGPGPQRGGLKHLKSIRNAA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHCCCHHCCCCCCCCHHHHHHHHHHHE
IHVVDGRIRDFGPAERVAVGLPKGAEPRVLDAAGGAVVPGFVDCHTHLLYSGSRADEYPM
EEEECCCCCCCCCHHHEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHEECCCCCCCCCE
RVAGASYGEISSRGGGVTRTIRESSDATSSELKQALTVRLAKALLNGTTTAEIKTGYWVD
EECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEC
PEGEGAALGIIAEVSASQPVDLVQTFHVALGTPARFGGAGEYARYVIDYVLPSVASHARF
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CDVVCDVGAFSHDEARQILHAAGRRGLNFKIHADEFSAAGGAELAAELGAVSADHLCFLG
HHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEC
KDTAQTLAKAQTVAVLLPATCHYLLAPKFADARHLIDGGVAIALGTDHGPGSPTLSMPFV
CHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCHHHH
MGLACSWLRMDPAEALVAATCNAAHAIGAASTAGQIAIGRPADLVVLKTPTYRDLAYLID
HHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHH
QNLIRYTLKDGAVFGKHIK
CHHHEEEECCCCCCCCCCC
>Mature Secondary Structure 
PNNPTTSTSATSGPNSNLRKGEAGGLLITNIAELTPLDEFGPGPQRGGLKHLKSIRNAA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHCCCHHCCCCCCCCHHHHHHHHHHHE
IHVVDGRIRDFGPAERVAVGLPKGAEPRVLDAAGGAVVPGFVDCHTHLLYSGSRADEYPM
EEEECCCCCCCCCHHHEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHEECCCCCCCCCE
RVAGASYGEISSRGGGVTRTIRESSDATSSELKQALTVRLAKALLNGTTTAEIKTGYWVD
EECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEC
PEGEGAALGIIAEVSASQPVDLVQTFHVALGTPARFGGAGEYARYVIDYVLPSVASHARF
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CDVVCDVGAFSHDEARQILHAAGRRGLNFKIHADEFSAAGGAELAAELGAVSADHLCFLG
HHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEC
KDTAQTLAKAQTVAVLLPATCHYLLAPKFADARHLIDGGVAIALGTDHGPGSPTLSMPFV
CHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCHHHH
MGLACSWLRMDPAEALVAATCNAAHAIGAASTAGQIAIGRPADLVVLKTPTYRDLAYLID
HHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHH
QNLIRYTLKDGAVFGKHIK
CHHHEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]