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The map label for this gene is farR [C]

Identifier: 13488225

GI number: 13488225

Start: 136649

End: 137350

Strand: Direct

Name: farR [C]

Synonym: mlr9157

Alternate gene names: 13488225

Gene position: 136649-137350 (Clockwise)

Preceding gene: 13488224

Following gene: 13488226

Centisome position: 38.83

GC content: 53.42

Gene sequence:

>702_bases
ATGAACGAGCTGCCGCGGTGGAGGCAGATCGAACTGACACTCCTGAAGGAAATCGATTCCGGCGCTTTCAGGGTTGGGCA
AAAGCTGCCGGGCGAAAATGTGCTTGCGCCTCATTTTGGCGTTACCAGGACAACGGTCCGGCGGGCATTGGGAGAACTAC
AAAATAAGGGCGTGCTGCGTATTGAACGTGGACGTGGCGCCTTCGTAGAGCGTCGGATTCAGTACGGACTTGGCGCCGGG
TCTTCCTTTATGGCTAACCTTCGCGACGCGAGCTTGGAGCCCGCGGTAGAGATTCTTGCGAAGTTTGAGGTGTCTGCCTC
TACGGAAATCGCAAATCGACTGCAGATACCGATAGGTGAGCCCGTCCTCGTCATCGATACGGTTGGTAAGGCAAGCGATC
TGACGATCTCAGTTTCGCGGCATCACTTGCCTTTGCGCCTTTTTCCAGATGCACTCAATCGGATCTCGAGTTTTTCCTGC
ATCACTGAAGTCTATCGGCTCTTTGGATACGAAAATACGCGTCGTACTCATTGTCACATAGAAGCGCGCTTGCCCTCGTC
TGAAGAAGCCAGACGGCTCGAACAGCCAAAGACCGAACCCATCCTTGAAGTGGAAAGTGTGAAAATGATCGACCAAACCC
CGATCGACTACAGCATCGGTCGCTTCTCAGCTGCGCGGGTCTCGGTATATTTTGATAATTGA

Upstream 100 bases:

>100_bases
TGTTCAGACATGTCAACATGGCGGTGCAGATCGCACAGTTTCATGACAGTGAGATGACTATTCGAAAGAGAAACGAATGA
ATGAGATGAGCCACGAGTTG

Downstream 100 bases:

>100_bases
ATCGACTACTCGCCCTCCCGCAGCCAGTCGCCAGGGAAATTCAGCGTGACGGGTCGCCCGGAGTACGGCTGCTCCTCCCG
CGATGTTGGTGGCGCTCCAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNELPRWRQIELTLLKEIDSGAFRVGQKLPGENVLAPHFGVTRTTVRRALGELQNKGVLRIERGRGAFVERRIQYGLGAG
SSFMANLRDASLEPAVEILAKFEVSASTEIANRLQIPIGEPVLVIDTVGKASDLTISVSRHHLPLRLFPDALNRISSFSC
ITEVYRLFGYENTRRTHCHIEARLPSSEEARRLEQPKTEPILEVESVKMIDQTPIDYSIGRFSAARVSVYFDN

Sequences:

>Translated_233_residues
MNELPRWRQIELTLLKEIDSGAFRVGQKLPGENVLAPHFGVTRTTVRRALGELQNKGVLRIERGRGAFVERRIQYGLGAG
SSFMANLRDASLEPAVEILAKFEVSASTEIANRLQIPIGEPVLVIDTVGKASDLTISVSRHHLPLRLFPDALNRISSFSC
ITEVYRLFGYENTRRTHCHIEARLPSSEEARRLEQPKTEPILEVESVKMIDQTPIDYSIGRFSAARVSVYFDN
>Mature_233_residues
MNELPRWRQIELTLLKEIDSGAFRVGQKLPGENVLAPHFGVTRTTVRRALGELQNKGVLRIERGRGAFVERRIQYGLGAG
SSFMANLRDASLEPAVEILAKFEVSASTEIANRLQIPIGEPVLVIDTVGKASDLTISVSRHHLPLRLFPDALNRISSFSC
ITEVYRLFGYENTRRTHCHIEARLPSSEEARRLEQPKTEPILEVESVKMIDQTPIDYSIGRFSAARVSVYFDN

Specific function: Possible Transcriptional Regulator Of The Succinyl-CoA- Synthetase Operon. Binds Specifically To The Farr Promoter And Exhibits Weak Binding To The Citrate Synthase And Lipoamide Dehydrogenase Promoters. Binding At The Farr Promoter Is Abolished By Long-

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=229, Percent_Identity=29.2576419213974, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790540, Length=219, Percent_Identity=31.9634703196347, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788418, Length=222, Percent_Identity=25.2252252252252, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012702
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26200; Mature: 26200

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELPRWRQIELTLLKEIDSGAFRVGQKLPGENVLAPHFGVTRTTVRRALGELQNKGVLR
CCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCEEE
IERGRGAFVERRIQYGLGAGSSFMANLRDASLEPAVEILAKFEVSASTEIANRLQIPIGE
EECCCCHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHEECCCCC
PVLVIDTVGKASDLTISVSRHHLPLRLFPDALNRISSFSCITEVYRLFGYENTRRTHCHI
CEEEEECCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
EARLPSSEEARRLEQPKTEPILEVESVKMIDQTPIDYSIGRFSAARVSVYFDN
EEECCCCHHHHHHCCCCCCCCEEHHHHHHHCCCCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MNELPRWRQIELTLLKEIDSGAFRVGQKLPGENVLAPHFGVTRTTVRRALGELQNKGVLR
CCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCEEE
IERGRGAFVERRIQYGLGAGSSFMANLRDASLEPAVEILAKFEVSASTEIANRLQIPIGE
EECCCCHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHEECCCCC
PVLVIDTVGKASDLTISVSRHHLPLRLFPDALNRISSFSCITEVYRLFGYENTRRTHCHI
CEEEEECCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
EARLPSSEEARRLEQPKTEPILEVESVKMIDQTPIDYSIGRFSAARVSVYFDN
EEECCCCHHHHHHCCCCCCCCEEHHHHHHHCCCCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431; 9889346 [H]