Click here to switch to the map view.

The map label for this gene is atoC [C]

Identifier: 13488173

GI number: 13488173

Start: 341575

End: 343404

Strand: Reverse

Name: atoC [C]

Synonym: mll9384

Alternate gene names: 13488173

Gene position: 343404-341575 (Counterclockwise)

Preceding gene: 13488174

Following gene: 13488172

Centisome position: 97.58

GC content: 60.0

Gene sequence:

>1830_bases
ATGGCTGATCCGATCACTCATTCTGTGAATCTTTTTTCTGCATTCTCCGCCCCCGCGCATGTTGGAGCGGAGATCGTTGC
GGGCCTCAAGGCTACGCTGGGAAAGCCCAATTCGACGCTCGTAGGCGCCGCAATCGGCACGGGCATGGCCGCGCAGGCGG
CCTCACGCGGCGGTGCGGACTTTCTCCTCGCGTTGAGTGCAGGACGATTGCGGAGCATGGGTGCCCCATCCATCTTTTCC
CTGCTCGCATTGCGCAACAGCAATGACTTCGTCCTGGATTTCGCCCAATCGGAAATCCTGCCCTTCGCCAAAGTTCCCGT
TTTCTTCGGCGCCTGTGCTTGTGATCCTCGGTGCTCGATAGAAGCTGAATTGCAAACAATTGCGGATGCCGGCTTTGGGG
CGATCGTGAACTTCCCGACATGCATCTTCCTCGACGGCCGCTTTCGAGCTGACATCGAGAGAGCAGGCTTGGGGTTCCAG
CGTGAACTCGAAATGCTCCGGGCCGCGCAGAACAAAAGCATGGCGACCCTCGCCTATGTTCGAACTGTGACAGAGGCACA
GCAGGCGGCCGAAGCCGGCGTGGACATCATCAATCTCAATCTCGGCTGGAACGTCGGAGGAACCGTCGGAGGCCGCCCCG
GGCTCAGCCTGACGCAGGCGGCCGAGTTTGCGAAGATCGTCTTTCGTCAGATACGCGGCATTTCAAAGGACACCCTATGT
GTTCTGGAGGGCGGCCCTATCGTCAGCCCGGACCAGATGTACGAGGTCTCGGCGGCTTCCAAAGCCGACGGATATATCGG
CGGCTCCACCATCGACCGAGTGCCCCTCGAGGCTTCGATTGAGCAGATCACATCGGCCTTTAAATCCGTCGGCACATTGC
AAAAGCGGATTGATGAACTGGAGCGCCAACTCGAACATGTGCAGCGCGAATACTGGATCGTCGGGCGGTCGCCGTCGATC
CAGCAGATCAAGCAACGGATCAAACAACTCGCAGCCTCTCCTCTCCCGGTCCTGATTACCGGGGAGGCCGGAACGGGAAA
GAGGCTTCTGGCACGAGGCATTCATGAAGCTGCGAGACGGCCTGCCAGCAAGCTCATCAGTGCGAGCACCCCGGTGCCAA
GCGGAAAGTCACTGTTCGGCTCTGCCCCCCCCGAGGGCGGCCGCAAGGTGCTTGGGCTGTTTCAGTACCATCCCAGGGCA
ACGTTGCTGATCGAGAATTTCGAAACCCTGTGCCTTGACGCCCAGGAACGGCTGGTGGAGGTCATTGAAACTGGTGTCTA
CCGGCGCCTAGGCGATAGCGACAAAGGGCGGTTCGAAGGACGCCTCATCCTGACATCGACGCAGCCGCTCTCCCAGCTCG
GCGCAAGCGGGGTGCTGATACCTTCGCTAGAGTCGCGTCTCGCCCCCGGACACGTCTTCCTTCCCAAACTGCGCGATCGC
CTAGAAGACCTTCCCCTTCTTGCGGAACACTTCCTCCAGGCCCTCCGAAAAGATCGTCGCAGCCGCAAACTGGCGGTTGA
CCACTCGGCCTATCGGGTTCTCATGACATATGGCTGGCCCGAGAACATCCGTGAGCTGCGCTCCGTGCTCGAGACCGCCG
CCATTCATTGCGAAGGCGACTGGATCAAGGCCGAGCATCTGCCGCCCCTAAGCGATCCGGACGCGCCGAAGCCGAAGCCG
GCAGACGAACGTGAATGGATACTCGACGCACTTCAGCGTCATCGTTTCCGCCGCGGAGAAACAGCGCGCTATCTCGCGAT
TTCGCGAAAGACCCTTTACAACAAAATGCGCGCTTACGGCCTAACTTTGCAGCCACGGACAAACGCGTAG

Upstream 100 bases:

>100_bases
AAGCGCACGCCTCGGCCAACCCGTGAAAGTACAGGAATTCCTCCAGTCCTTCAGAAAGAGCGCTTCGATCGAGACCCAAT
AGGATGTAGTTTGCCTCACA

Downstream 100 bases:

>100_bases
GCCAAGGAACCCTGCCTGATCTACAAGACACTTTCAATTTATCGCGGACCGCTGCTCCGCTGATTGTGAATGCCCCTTCT
AAGCATCGCAGTGGCGTCGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MADPITHSVNLFSAFSAPAHVGAEIVAGLKATLGKPNSTLVGAAIGTGMAAQAASRGGADFLLALSAGRLRSMGAPSIFS
LLALRNSNDFVLDFAQSEILPFAKVPVFFGACACDPRCSIEAELQTIADAGFGAIVNFPTCIFLDGRFRADIERAGLGFQ
RELEMLRAAQNKSMATLAYVRTVTEAQQAAEAGVDIINLNLGWNVGGTVGGRPGLSLTQAAEFAKIVFRQIRGISKDTLC
VLEGGPIVSPDQMYEVSAASKADGYIGGSTIDRVPLEASIEQITSAFKSVGTLQKRIDELERQLEHVQREYWIVGRSPSI
QQIKQRIKQLAASPLPVLITGEAGTGKRLLARGIHEAARRPASKLISASTPVPSGKSLFGSAPPEGGRKVLGLFQYHPRA
TLLIENFETLCLDAQERLVEVIETGVYRRLGDSDKGRFEGRLILTSTQPLSQLGASGVLIPSLESRLAPGHVFLPKLRDR
LEDLPLLAEHFLQALRKDRRSRKLAVDHSAYRVLMTYGWPENIRELRSVLETAAIHCEGDWIKAEHLPPLSDPDAPKPKP
ADEREWILDALQRHRFRRGETARYLAISRKTLYNKMRAYGLTLQPRTNA

Sequences:

>Translated_609_residues
MADPITHSVNLFSAFSAPAHVGAEIVAGLKATLGKPNSTLVGAAIGTGMAAQAASRGGADFLLALSAGRLRSMGAPSIFS
LLALRNSNDFVLDFAQSEILPFAKVPVFFGACACDPRCSIEAELQTIADAGFGAIVNFPTCIFLDGRFRADIERAGLGFQ
RELEMLRAAQNKSMATLAYVRTVTEAQQAAEAGVDIINLNLGWNVGGTVGGRPGLSLTQAAEFAKIVFRQIRGISKDTLC
VLEGGPIVSPDQMYEVSAASKADGYIGGSTIDRVPLEASIEQITSAFKSVGTLQKRIDELERQLEHVQREYWIVGRSPSI
QQIKQRIKQLAASPLPVLITGEAGTGKRLLARGIHEAARRPASKLISASTPVPSGKSLFGSAPPEGGRKVLGLFQYHPRA
TLLIENFETLCLDAQERLVEVIETGVYRRLGDSDKGRFEGRLILTSTQPLSQLGASGVLIPSLESRLAPGHVFLPKLRDR
LEDLPLLAEHFLQALRKDRRSRKLAVDHSAYRVLMTYGWPENIRELRSVLETAAIHCEGDWIKAEHLPPLSDPDAPKPKP
ADEREWILDALQRHRFRRGETARYLAISRKTLYNKMRAYGLTLQPRTNA
>Mature_608_residues
ADPITHSVNLFSAFSAPAHVGAEIVAGLKATLGKPNSTLVGAAIGTGMAAQAASRGGADFLLALSAGRLRSMGAPSIFSL
LALRNSNDFVLDFAQSEILPFAKVPVFFGACACDPRCSIEAELQTIADAGFGAIVNFPTCIFLDGRFRADIERAGLGFQR
ELEMLRAAQNKSMATLAYVRTVTEAQQAAEAGVDIINLNLGWNVGGTVGGRPGLSLTQAAEFAKIVFRQIRGISKDTLCV
LEGGPIVSPDQMYEVSAASKADGYIGGSTIDRVPLEASIEQITSAFKSVGTLQKRIDELERQLEHVQREYWIVGRSPSIQ
QIKQRIKQLAASPLPVLITGEAGTGKRLLARGIHEAARRPASKLISASTPVPSGKSLFGSAPPEGGRKVLGLFQYHPRAT
LLIENFETLCLDAQERLVEVIETGVYRRLGDSDKGRFEGRLILTSTQPLSQLGASGVLIPSLESRLAPGHVFLPKLRDRL
EDLPLLAEHFLQALRKDRRSRKLAVDHSAYRVLMTYGWPENIRELRSVLETAAIHCEGDWIKAEHLPPLSDPDAPKPKPA
DEREWILDALQRHRFRRGETARYLAISRKTLYNKMRAYGLTLQPRTNA

Specific function: Probable transcriptional regulator that acts in conjunction with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=333, Percent_Identity=31.8318318318318, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1790437, Length=302, Percent_Identity=31.4569536423841, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789087, Length=394, Percent_Identity=27.6649746192893, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87082117, Length=354, Percent_Identity=28.8135593220339, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787583, Length=326, Percent_Identity=29.7546012269939, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=28.4375, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1790299, Length=334, Percent_Identity=27.5449101796407, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=28.6604361370716, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081858, Length=290, Percent_Identity=29.3103448275862, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081872, Length=238, Percent_Identity=31.0924369747899, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788905, Length=249, Percent_Identity=30.5220883534137, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786524, Length=326, Percent_Identity=29.4478527607362, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR009215 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF09370 TIM-br_sig_trns [H]

EC number: NA

Molecular weight: Translated: 66269; Mature: 66138

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPITHSVNLFSAFSAPAHVGAEIVAGLKATLGKPNSTLVGAAIGTGMAAQAASRGGAD
CCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCHHHHHHCCCCCE
FLLALSAGRLRSMGAPSIFSLLALRNSNDFVLDFAQSEILPFAKVPVFFGACACDPRCSI
EEEEECCCHHHCCCCHHHHHHHHHCCCCCEEEEECHHCCCCHHHHHHHHHCCCCCCCCCC
EAELQTIADAGFGAIVNFPTCIFLDGRFRADIERAGLGFQRELEMLRAAQNKSMATLAYV
HHHHHHHHHCCCCCEECCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHH
RTVTEAQQAAEAGVDIINLNLGWNVGGTVGGRPGLSLTQAAEFAKIVFRQIRGISKDTLC
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VLEGGPIVSPDQMYEVSAASKADGYIGGSTIDRVPLEASIEQITSAFKSVGTLQKRIDEL
EEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERQLEHVQREYWIVGRSPSIQQIKQRIKQLAASPLPVLITGEAGTGKRLLARGIHEAARR
HHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHC
PASKLISASTPVPSGKSLFGSAPPEGGRKVLGLFQYHPRATLLIENFETLCLDAQERLVE
CHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEECCCEEEEECCHHHHHHHHHHHHHH
VIETGVYRRLGDSDKGRFEGRLILTSTQPLSQLGASGVLIPSLESRLAPGHVFLPKLRDR
HHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHCCCCEEECCHHHHCCCCCEEHHHHHHH
LEDLPLLAEHFLQALRKDRRSRKLAVDHSAYRVLMTYGWPENIRELRSVLETAAIHCEGD
HHCCHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHEECCCC
WIKAEHLPPLSDPDAPKPKPADEREWILDALQRHRFRRGETARYLAISRKTLYNKMRAYG
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
LTLQPRTNA
CEECCCCCC
>Mature Secondary Structure 
ADPITHSVNLFSAFSAPAHVGAEIVAGLKATLGKPNSTLVGAAIGTGMAAQAASRGGAD
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCHHHHHHCCCCCE
FLLALSAGRLRSMGAPSIFSLLALRNSNDFVLDFAQSEILPFAKVPVFFGACACDPRCSI
EEEEECCCHHHCCCCHHHHHHHHHCCCCCEEEEECHHCCCCHHHHHHHHHCCCCCCCCCC
EAELQTIADAGFGAIVNFPTCIFLDGRFRADIERAGLGFQRELEMLRAAQNKSMATLAYV
HHHHHHHHHCCCCCEECCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHH
RTVTEAQQAAEAGVDIINLNLGWNVGGTVGGRPGLSLTQAAEFAKIVFRQIRGISKDTLC
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VLEGGPIVSPDQMYEVSAASKADGYIGGSTIDRVPLEASIEQITSAFKSVGTLQKRIDEL
EEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERQLEHVQREYWIVGRSPSIQQIKQRIKQLAASPLPVLITGEAGTGKRLLARGIHEAARR
HHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHC
PASKLISASTPVPSGKSLFGSAPPEGGRKVLGLFQYHPRATLLIENFETLCLDAQERLVE
CHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEECCCEEEEECCHHHHHHHHHHHHHH
VIETGVYRRLGDSDKGRFEGRLILTSTQPLSQLGASGVLIPSLESRLAPGHVFLPKLRDR
HHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHCCCCEEECCHHHHCCCCCEEHHHHHHH
LEDLPLLAEHFLQALRKDRRSRKLAVDHSAYRVLMTYGWPENIRELRSVLETAAIHCEGD
HHCCHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHEECCCC
WIKAEHLPPLSDPDAPKPKPADEREWILDALQRHRFRRGETARYLAISRKTLYNKMRAYG
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
LTLQPRTNA
CEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]