Click here to switch to the map view.

The map label for this gene is amn [H]

Identifier: 161621444

GI number: 161621444

Start: 6389397

End: 6390902

Strand: Reverse

Name: amn [H]

Synonym: mll7714

Alternate gene names: 161621444

Gene position: 6390902-6389397 (Counterclockwise)

Preceding gene: 13476404

Following gene: 13476402

Centisome position: 90.83

GC content: 63.68

Gene sequence:

>1506_bases
ATGGAAAAGCGAATCTACCCTCAAGCCATCGAATCCGTCGTCATGCCCGAGCCTTTTGGCCGGCAAAGCTTCGACAGCGC
CGAAAAAGCCGTCGCCGCACTGCAGCGGCTTTACGATCGCAACACCAAGTTCCTGCGCGACGCCTTCGCGGCCCTGGCGT
CGGCCGGCGGAGACAGCAGCAAGCGCTACCGCGCCTTCTACCCCGAGATCGGCGTCACCACGAGTTCGTTCACCCAGGTC
GACTCGCGCCAAGCCTACGGCCATATGCCGACACCCGGCCATTTCGCCACCACGATCACACAGCCGCAGCTGTTCGAGCG
CTACCTGATCGAACAGCTGCGCCTCATCATGCGCAACCACGGTGTCTCGGTCACGGTTTCGGAATCGACCACGCCCATTC
CGCTGCATTTCGCCTTCTTGGAGGGAACTTACGTCGACGGGGCCGCCGCGGAGCGCATCAAGCGGCCGATCCGCGACCTG
TTCGACGTGCCGGATCTCGACGGCACCGACGACCAGATCGCCAACGGCACGTTCGAGGTGGCCTTCGGCGAACCAAGGCC
GCTGGCGCCGTTCACGGCGCAGCGCATCGACTATTCGCTGCACCGCATGACGCATTATACGGCAACCAGCCCGCAGCATT
TCCAGAACTTCGTGCTGTTCACCAACTACCAGTTCTACATCGACGAATTCGTCGCCCGCGCCCGCGACCTGATGGAGAAG
GGCGGTGGCGGTTACGCGGAATTCGTAGAGCCGGGCAATGTCGTGACCAAAGCCGGGCAGAGTTCGCCTAGCGAAGGCGT
TGGGCCGCAGCGCCTTCCGCAGATGCCGGCCTATCACCTGAAAAAGCCGAACCATGGCGGCATCACAATGGTCAACATTG
GTGTTGGCCCTTCCAATGCCAAGACGATCACCGACCATATCGCCGTGCTGAGGCCGCATGCCTGGGTGATGCTTGGCCAT
TGCGCCGGGCTGCGCAACACCCAGGCGCTCGGCGACTATGTGCTGGCGCATGCCTATGTGCGCGAGGACCATGTGCTGGA
CGACGACCTTCCGGTCTGGGTGCCGATCCCGCCGCTGGCGGAAATCCAGGTTGCGCTGCAGGAAGCGGTCGCCGAAGTCA
CCGGCCTGTCCGGCTACGATCTGAAGCGCATCATGCGCACCGGCACGGTCGCCACCATCGACAACCGCAACTGGGAACTG
CGCGACCAGCGCGGACCGGTGCAGCGCCTGTCGCAGTCGCGCGCCATCGCGCTCGACATGGAATCGGCGACGATCGCCGC
CAATGGCTTCCGCTTCCGCGTGCCCTACGGCACGCTGCTGTGCGTTTCCGACAAGCCGCTGCATGGCGAGTTGAAACTGC
CGGGCATGGCGACGGAGTTCTACAAGCGGCAGGTGGCGCAGCACCTGACCATCGGCATCAGGGCGATGGAGAAGCTGGCC
GAGATGCCGATGGAGCGGCTGCATTCGCGCAAGCTCCGGAGCTTTTCGGAGACAGCGTTCCAATAG

Upstream 100 bases:

>100_bases
TGCTGGTCAGCCTGCAGCGGGGATAAAGAAAAATGGCGCTTTGGGCGCCTTCGGCGGCGAGCCCCCTCCCAACCGCCCGT
CCAAGTCTCTATATTGAGCC

Downstream 100 bases:

>100_bases
GCGGCCGCAGCGCCTGGGCGAGGCATTTCGTCGTCTTGCCCAGGCCGCAATTCGGCCGATAAGCAGATGGAACGGATCGT
CAGGCGGCATTCGGCAGACA

Product: AMP nucleosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MEKRIYPQAIESVVMPEPFGRQSFDSAEKAVAALQRLYDRNTKFLRDAFAALASAGGDSSKRYRAFYPEIGVTTSSFTQV
DSRQAYGHMPTPGHFATTITQPQLFERYLIEQLRLIMRNHGVSVTVSESTTPIPLHFAFLEGTYVDGAAAERIKRPIRDL
FDVPDLDGTDDQIANGTFEVAFGEPRPLAPFTAQRIDYSLHRMTHYTATSPQHFQNFVLFTNYQFYIDEFVARARDLMEK
GGGGYAEFVEPGNVVTKAGQSSPSEGVGPQRLPQMPAYHLKKPNHGGITMVNIGVGPSNAKTITDHIAVLRPHAWVMLGH
CAGLRNTQALGDYVLAHAYVREDHVLDDDLPVWVPIPPLAEIQVALQEAVAEVTGLSGYDLKRIMRTGTVATIDNRNWEL
RDQRGPVQRLSQSRAIALDMESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPGMATEFYKRQVAQHLTIGIRAMEKLA
EMPMERLHSRKLRSFSETAFQ

Sequences:

>Translated_501_residues
MEKRIYPQAIESVVMPEPFGRQSFDSAEKAVAALQRLYDRNTKFLRDAFAALASAGGDSSKRYRAFYPEIGVTTSSFTQV
DSRQAYGHMPTPGHFATTITQPQLFERYLIEQLRLIMRNHGVSVTVSESTTPIPLHFAFLEGTYVDGAAAERIKRPIRDL
FDVPDLDGTDDQIANGTFEVAFGEPRPLAPFTAQRIDYSLHRMTHYTATSPQHFQNFVLFTNYQFYIDEFVARARDLMEK
GGGGYAEFVEPGNVVTKAGQSSPSEGVGPQRLPQMPAYHLKKPNHGGITMVNIGVGPSNAKTITDHIAVLRPHAWVMLGH
CAGLRNTQALGDYVLAHAYVREDHVLDDDLPVWVPIPPLAEIQVALQEAVAEVTGLSGYDLKRIMRTGTVATIDNRNWEL
RDQRGPVQRLSQSRAIALDMESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPGMATEFYKRQVAQHLTIGIRAMEKLA
EMPMERLHSRKLRSFSETAFQ
>Mature_501_residues
MEKRIYPQAIESVVMPEPFGRQSFDSAEKAVAALQRLYDRNTKFLRDAFAALASAGGDSSKRYRAFYPEIGVTTSSFTQV
DSRQAYGHMPTPGHFATTITQPQLFERYLIEQLRLIMRNHGVSVTVSESTTPIPLHFAFLEGTYVDGAAAERIKRPIRDL
FDVPDLDGTDDQIANGTFEVAFGEPRPLAPFTAQRIDYSLHRMTHYTATSPQHFQNFVLFTNYQFYIDEFVARARDLMEK
GGGGYAEFVEPGNVVTKAGQSSPSEGVGPQRLPQMPAYHLKKPNHGGITMVNIGVGPSNAKTITDHIAVLRPHAWVMLGH
CAGLRNTQALGDYVLAHAYVREDHVLDDDLPVWVPIPPLAEIQVALQEAVAEVTGLSGYDLKRIMRTGTVATIDNRNWEL
RDQRGPVQRLSQSRAIALDMESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPGMATEFYKRQVAQHLTIGIRAMEKLA
EMPMERLHSRKLRSFSETAFQ

Specific function: Involved in regulation of AMP concentrations [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788293, Length=482, Percent_Identity=46.0580912863071, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011271
- InterPro:   IPR018953
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF10423 AMNp_N; PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.4 [H]

Molecular weight: Translated: 55923; Mature: 55923

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRIYPQAIESVVMPEPFGRQSFDSAEKAVAALQRLYDRNTKFLRDAFAALASAGGDSS
CCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KRYRAFYPEIGVTTSSFTQVDSRQAYGHMPTPGHFATTITQPQLFERYLIEQLRLIMRNH
CCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCC
GVSVTVSESTTPIPLHFAFLEGTYVDGAAAERIKRPIRDLFDVPDLDGTDDQIANGTFEV
CCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEEE
AFGEPRPLAPFTAQRIDYSLHRMTHYTATSPQHFQNFVLFTNYQFYIDEFVARARDLMEK
EECCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHH
GGGGYAEFVEPGNVVTKAGQSSPSEGVGPQRLPQMPAYHLKKPNHGGITMVNIGVGPSNA
CCCCEEHHCCCCCCEECCCCCCCCCCCCHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCC
KTITDHIAVLRPHAWVMLGHCAGLRNTQALGDYVLAHAYVREDHVLDDDLPVWVPIPPLA
HHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
EIQVALQEAVAEVTGLSGYDLKRIMRTGTVATIDNRNWELRDQRGPVQRLSQSRAIALDM
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCEECCCCCHHHHHHCCCEEEEEE
ESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPGMATEFYKRQVAQHLTIGIRAMEKLA
CCCEEEECCEEEECCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
EMPMERLHSRKLRSFSETAFQ
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKRIYPQAIESVVMPEPFGRQSFDSAEKAVAALQRLYDRNTKFLRDAFAALASAGGDSS
CCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KRYRAFYPEIGVTTSSFTQVDSRQAYGHMPTPGHFATTITQPQLFERYLIEQLRLIMRNH
CCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCC
GVSVTVSESTTPIPLHFAFLEGTYVDGAAAERIKRPIRDLFDVPDLDGTDDQIANGTFEV
CCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEEE
AFGEPRPLAPFTAQRIDYSLHRMTHYTATSPQHFQNFVLFTNYQFYIDEFVARARDLMEK
EECCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHH
GGGGYAEFVEPGNVVTKAGQSSPSEGVGPQRLPQMPAYHLKKPNHGGITMVNIGVGPSNA
CCCCEEHHCCCCCCEECCCCCCCCCCCCHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCC
KTITDHIAVLRPHAWVMLGHCAGLRNTQALGDYVLAHAYVREDHVLDDDLPVWVPIPPLA
HHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
EIQVALQEAVAEVTGLSGYDLKRIMRTGTVATIDNRNWELRDQRGPVQRLSQSRAIALDM
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCEECCCCCHHHHHHCCCEEEEEE
ESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPGMATEFYKRQVAQHLTIGIRAMEKLA
CCCEEEECCEEEECCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
EMPMERLHSRKLRSFSETAFQ
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]