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The map label for this gene is hipO [H]

Identifier: 13476576

GI number: 13476576

Start: 6554689

End: 6555828

Strand: Direct

Name: hipO [H]

Synonym: mlr7940

Alternate gene names: 13476576

Gene position: 6554689-6555828 (Clockwise)

Preceding gene: 13476575

Following gene: 13476579

Centisome position: 93.16

GC content: 65.18

Gene sequence:

>1140_bases
ATGCTGAAGCGCGAGATGACCGATTGGCGGCGCGACCTGCACGCGCACCCCGAATTCGGCTTCGAGGAGAAACGCACCGC
GGCCTTCGTCGCCGCCAAGCTGCGCGAATTCGGTCTGGACGATGTCGCAGAGGGTGTCGGCGGCACCGGCGTCGTCGGCA
CATTGAAGCGCGGCAGCGGCAATCGCGCCATTGCGCTGCGGGCCGATATGGATGCCCTGCGCATATCGGAGCAATCGAGC
GCACCCTACCGCTCCGGCAATCCGGGCGTGATGCACGCCTGCGGCCATGATGGCCACACCGCCATGCTGCTTGGCGCGGC
AAAGCTGCTGGCGAGCGAGGGTGGTTTCGACGGCACCGTGCGCTTCATCTTCCAGCCGGCCGAGGAGTGGGGCAGGGGTG
CGCTGGCCATGATCGACGATGGCCTGATGCAGCGCTTCCCCTTCGACGAGATATTTGGCCTGCACAACATGCCCGGCCTT
CCCGTCGGACACCTCGAGACCCGCGCCGGTCCCATAATGTCGGCCGAGGATAATTTCGAGATCATGCTCAGGGGGCTCGG
CGGCCACGCGGCGCGGCCGCATTCGGGCAATGAAACGCTGATCGCCGCCTGCGCGCTGGTCACGAACCTGCAGACCATCG
TCTCGCGCCGCCTGAGCCCGGCCGACATAGCGGTGGTTTCGGTGACCGAACTGATCACCGACGGCACCCGCAATGCACTG
CCCGGTCTTGCCCGCATCCTCGGCGACGCGCGCAGTTTCCGCCCCGAGGTCAGCGCGGAGATCGAACGCCAGATGCGCAC
CATCGCCGAGGGCACCGCGGCCGCCTACAATGTGACCGCCGAGGTCAATTACACCAGGGAATTCGTGCCCTTGCACAATG
ATGCCGAACTGGTCGAGGCCACCTTCGCCGCCGCCAAAAAAGTCTTCGATCCTCGCAATATCGCGGTTGCCCGCGAGCCG
ATGACGGCGTCGGAGGATTTTGCCCGCTTCCTCGATCACGTGCCGGGCTGCTTCGTCTTCCTCGGCAATGGTGAGGCCTC
GGCGCCGCTGCACAATTCCAGCTATGACTTCAATGATGATGGGCTGGTGTTCGGCGCCGGTTTCCATGCCGCCATCGCCA
GGCAACGGCTCGGAATTTGA

Upstream 100 bases:

>100_bases
GAGGATGCCGAGCTTGTTGCCGGCGCCAACATCCTGCTTGATGTGGTCGCTGAACTCGCCGAGCTCGAAGGCTGAAGAAA
TGGCTGAACTCGATCCAGAA

Downstream 100 bases:

>100_bases
CCGGCGACGAACCCTCTTCGGCACGCTTTTGCCGGTGGAAAACGCTCGGAAAGGGCCGAAATCCGCGATCCCGCATGACG
CAGAGGCAAGACTCAGGTAC

Product: hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLKREMTDWRRDLHAHPEFGFEEKRTAAFVAAKLREFGLDDVAEGVGGTGVVGTLKRGSGNRAIALRADMDALRISEQSS
APYRSGNPGVMHACGHDGHTAMLLGAAKLLASEGGFDGTVRFIFQPAEEWGRGALAMIDDGLMQRFPFDEIFGLHNMPGL
PVGHLETRAGPIMSAEDNFEIMLRGLGGHAARPHSGNETLIAACALVTNLQTIVSRRLSPADIAVVSVTELITDGTRNAL
PGLARILGDARSFRPEVSAEIERQMRTIAEGTAAAYNVTAEVNYTREFVPLHNDAELVEATFAAAKKVFDPRNIAVAREP
MTASEDFARFLDHVPGCFVFLGNGEASAPLHNSSYDFNDDGLVFGAGFHAAIARQRLGI

Sequences:

>Translated_379_residues
MLKREMTDWRRDLHAHPEFGFEEKRTAAFVAAKLREFGLDDVAEGVGGTGVVGTLKRGSGNRAIALRADMDALRISEQSS
APYRSGNPGVMHACGHDGHTAMLLGAAKLLASEGGFDGTVRFIFQPAEEWGRGALAMIDDGLMQRFPFDEIFGLHNMPGL
PVGHLETRAGPIMSAEDNFEIMLRGLGGHAARPHSGNETLIAACALVTNLQTIVSRRLSPADIAVVSVTELITDGTRNAL
PGLARILGDARSFRPEVSAEIERQMRTIAEGTAAAYNVTAEVNYTREFVPLHNDAELVEATFAAAKKVFDPRNIAVAREP
MTASEDFARFLDHVPGCFVFLGNGEASAPLHNSSYDFNDDGLVFGAGFHAAIARQRLGI
>Mature_379_residues
MLKREMTDWRRDLHAHPEFGFEEKRTAAFVAAKLREFGLDDVAEGVGGTGVVGTLKRGSGNRAIALRADMDALRISEQSS
APYRSGNPGVMHACGHDGHTAMLLGAAKLLASEGGFDGTVRFIFQPAEEWGRGALAMIDDGLMQRFPFDEIFGLHNMPGL
PVGHLETRAGPIMSAEDNFEIMLRGLGGHAARPHSGNETLIAACALVTNLQTIVSRRLSPADIAVVSVTELITDGTRNAL
PGLARILGDARSFRPEVSAEIERQMRTIAEGTAAAYNVTAEVNYTREFVPLHNDAELVEATFAAAKKVFDPRNIAVAREP
MTASEDFARFLDHVPGCFVFLGNGEASAPLHNSSYDFNDDGLVFGAGFHAAIARQRLGI

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=414, Percent_Identity=30.1932367149758, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787598, Length=302, Percent_Identity=29.4701986754967, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 40827; Mature: 40827

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKREMTDWRRDLHAHPEFGFEEKRTAAFVAAKLREFGLDDVAEGVGGTGVVGTLKRGSG
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCC
NRAIALRADMDALRISEQSSAPYRSGNPGVMHACGHDGHTAMLLGAAKLLASEGGFDGTV
CEEEEEEECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEE
RFIFQPAEEWGRGALAMIDDGLMQRFPFDEIFGLHNMPGLPVGHLETRAGPIMSAEDNFE
EEEEECHHHHCCEEEEEHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCE
IMLRGLGGHAARPHSGNETLIAACALVTNLQTIVSRRLSPADIAVVSVTELITDGTRNAL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHH
PGLARILGDARSFRPEVSAEIERQMRTIAEGTAAAYNVTAEVNYTREFVPLHNDAELVEA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEEECCCCHHHHHH
TFAAAKKVFDPRNIAVAREPMTASEDFARFLDHVPGCFVFLGNGEASAPLHNSSYDFNDD
HHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCC
GLVFGAGFHAAIARQRLGI
CEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MLKREMTDWRRDLHAHPEFGFEEKRTAAFVAAKLREFGLDDVAEGVGGTGVVGTLKRGSG
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCC
NRAIALRADMDALRISEQSSAPYRSGNPGVMHACGHDGHTAMLLGAAKLLASEGGFDGTV
CEEEEEEECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEE
RFIFQPAEEWGRGALAMIDDGLMQRFPFDEIFGLHNMPGLPVGHLETRAGPIMSAEDNFE
EEEEECHHHHCCEEEEEHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCE
IMLRGLGGHAARPHSGNETLIAACALVTNLQTIVSRRLSPADIAVVSVTELITDGTRNAL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHH
PGLARILGDARSFRPEVSAEIERQMRTIAEGTAAAYNVTAEVNYTREFVPLHNDAELVEA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEEECCCCHHHHHH
TFAAAKKVFDPRNIAVAREPMTASEDFARFLDHVPGCFVFLGNGEASAPLHNSSYDFNDD
HHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCC
GLVFGAGFHAAIARQRLGI
CEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]