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The map label for this gene is pgsA [H]

Identifier: 13476556

GI number: 13476556

Start: 6537666

End: 6538262

Strand: Direct

Name: pgsA [H]

Synonym: mlr7913

Alternate gene names: 13476556

Gene position: 6537666-6538262 (Clockwise)

Preceding gene: 13476555

Following gene: 13476557

Centisome position: 92.92

GC content: 62.14

Gene sequence:

>597_bases
ATGGCCCAGCGCGCGTTCAACCTGCCCAACATGCTGACCTACGCCCGCATCATCGCGGTGCCGCTGGTGGTGCTGTGCTT
TTTTCTCGAAGGTCATCTGAAATCGAGCGACTTCGCCCGCTGGTCGGCGCTGGTCATTTTCCTGCTGGCGTCCGTCACCG
ATTATTTCGACGGCTATTTTGCGCGCGCCTGGCAGCAAACCTCCAACATCGGCAAGATGCTCGACCCGATCGCCGACAAG
CTACTGGTCGCGACCTGCCTTTTGCTGCTGGCGGCCGACACCGATCGCCATGCCGGCATTGCCGGCTGGTCGCTGTGGGC
GGCCATCATCATCCTGTGCCGCGAGATCCTGGTTTCTGGCCTGCGCGAATATCTGGCGGCGCTCAAGGTCTCGGTGCCGG
TGACGCAGCTTGCCAAGTGGAAGACCACTATCCAGATGGTCGCCATCGCCTTCCTGCTGGCGGGACCGGCCGGCGACAAG
ATCTTCCCGCTGACGACGCAGACCGGCCTCGTTTTGCTGTGGATAGCCGCACTCGTCACGCTCTACACCGGCTACGACTA
TTTCCGCGCCGGCCTCAAGCACATCATGGACGAGTGA

Upstream 100 bases:

>100_bases
TTGAAAATTCGGCACTTTCCGCTGGTCAGTCGAATCTGGCCTGTTGACCCCCTACATTGGCTTCTGATTTGAGTACGCAG
GCAGAAAGAGTCCACCAGAC

Downstream 100 bases:

>100_bases
AATGACGACCCGCCTCATCTATTTTGCCTGGGTGCGCGAACGGATCGGCACGTCAGAGGAAGACGTCGAATTGCCCGCCG
ACATCGAGACCGTCGCCGAC

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAQRAFNLPNMLTYARIIAVPLVVLCFFLEGHLKSSDFARWSALVIFLLASVTDYFDGYFARAWQQTSNIGKMLDPIADK
LLVATCLLLLAADTDRHAGIAGWSLWAAIIILCREILVSGLREYLAALKVSVPVTQLAKWKTTIQMVAIAFLLAGPAGDK
IFPLTTQTGLVLLWIAALVTLYTGYDYFRAGLKHIMDE

Sequences:

>Translated_198_residues
MAQRAFNLPNMLTYARIIAVPLVVLCFFLEGHLKSSDFARWSALVIFLLASVTDYFDGYFARAWQQTSNIGKMLDPIADK
LLVATCLLLLAADTDRHAGIAGWSLWAAIIILCREILVSGLREYLAALKVSVPVTQLAKWKTTIQMVAIAFLLAGPAGDK
IFPLTTQTGLVLLWIAALVTLYTGYDYFRAGLKHIMDE
>Mature_197_residues
AQRAFNLPNMLTYARIIAVPLVVLCFFLEGHLKSSDFARWSALVIFLLASVTDYFDGYFARAWQQTSNIGKMLDPIADKL
LVATCLLLLAADTDRHAGIAGWSLWAAIIILCREILVSGLREYLAALKVSVPVTQLAKWKTTIQMVAIAFLLAGPAGDKI
FPLTTQTGLVLLWIAALVTLYTGYDYFRAGLKHIMDE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=195, Percent_Identity=39.4871794871795, Blast_Score=120, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6320059, Length=169, Percent_Identity=31.9526627218935, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21927; Mature: 21796

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRAFNLPNMLTYARIIAVPLVVLCFFLEGHLKSSDFARWSALVIFLLASVTDYFDGYF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARAWQQTSNIGKMLDPIADKLLVATCLLLLAADTDRHAGIAGWSLWAAIIILCREILVSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LREYLAALKVSVPVTQLAKWKTTIQMVAIAFLLAGPAGDKIFPLTTQTGLVLLWIAALVT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHH
LYTGYDYFRAGLKHIMDE
HHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQRAFNLPNMLTYARIIAVPLVVLCFFLEGHLKSSDFARWSALVIFLLASVTDYFDGYF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARAWQQTSNIGKMLDPIADKLLVATCLLLLAADTDRHAGIAGWSLWAAIIILCREILVSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LREYLAALKVSVPVTQLAKWKTTIQMVAIAFLLAGPAGDKIFPLTTQTGLVLLWIAALVT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHH
LYTGYDYFRAGLKHIMDE
HHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA