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The map label for this gene is pip [H]

Identifier: 13476474

GI number: 13476474

Start: 6455910

End: 6456866

Strand: Direct

Name: pip [H]

Synonym: mlr7803

Alternate gene names: 13476474

Gene position: 6455910-6456866 (Clockwise)

Preceding gene: 13476473

Following gene: 13476475

Centisome position: 91.75

GC content: 64.37

Gene sequence:

>957_bases
ATGAGCAGCCAATTGCGTAGCCTCTATCCCGAGATCGAGGCGGTCGAGTCCGGCATGCTCGACGTCGGCGACGGCCATCA
GGTCTATTGGGAACGTTCCGGCACCAAGGGTGCCAAGCCGGCCGTGTTCCTGCATGGCGGGCCGGGCGGCACCATCTCGC
CAAAACACCGGCGGCTGTTCGACCCAAAGCTCTACGATGTCATCCTGTTCGACCAGCGCGGTTGCGGAAAGTCGACGCCG
AACGCCTCGCTGGAGGCCAACACCACCTGGCATCTCGTCGCCGACATAGAGCGGCTGCGCGAAATGGCCGGCTTCGATAC
ATGGCTGGTGTTCGGCGGCTCCTGGGGCTCGACGCTGGCGCTCGCCTATGCCGAGACGCATCCCGATCGCGTCAGCGAAC
TGGTGGTACGCGGCATCTATACGCTGACCCGCGCCGAGCTCGAATGGTATTATCAGTTCGGCGTCTCCGAGATGTTTCCC
GACAAGTGGGAGCGTTTCCTGGCGCCGATCCCCGAGACCGAGCGCGGTGACATGATGGCCGCCTACCGCAAGCGGCTGGT
CGGCTCGGACCGCAAGGCGCAGCTGGAAGCGGCCCGCGCGTGGAGCCTGTGGGAAGGCGAAACCATCACGCTGCTGCCCG
AGCCGGAAACCAGCGGCAAGTTTGGCGAGGACGACTATGCCGTCGCCTTCGCCCGCATCGAGAATCATTATTTCGTCCAT
GCCGGCTGGCTCGACGAAGGGCAGCTGCTGCGCGATGCCTGGAAGCTCAAGGATATCCCCGGCACCATCGTCCATGGCCG
CTACGACATGCCGTGTCCGGCACGTTACGCCTGGGCGCTGCACAAGGCCTGGCCGAAGGCCGATTTCCATCTGATCGAGG
GCGCCGGCCATGCCTATTCGGAGCCCGGCATCCTCGACCGGCTGATCCGCGCGACGGACAAATTTGCAGGCAAATGA

Upstream 100 bases:

>100_bases
TCCATCAGGACCCCGACTACTATGCCCGGCAGGAACAGATCATTTCCTTCCAGCACCCAGACCATGAAACAGCGGACTGG
CCGACCAAGGGTTTGCAGCT

Downstream 100 bases:

>100_bases
CCATGACCCGCGAGCGCCTCTATCTCTTCGACACCACATTGCGCGATGGCCAGCAGACGCCGGGCATCGACTTTTCCGTC
GAGGACAAGATCGCAATTGC

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSSQLRSLYPEIEAVESGMLDVGDGHQVYWERSGTKGAKPAVFLHGGPGGTISPKHRRLFDPKLYDVILFDQRGCGKSTP
NASLEANTTWHLVADIERLREMAGFDTWLVFGGSWGSTLALAYAETHPDRVSELVVRGIYTLTRAELEWYYQFGVSEMFP
DKWERFLAPIPETERGDMMAAYRKRLVGSDRKAQLEAARAWSLWEGETITLLPEPETSGKFGEDDYAVAFARIENHYFVH
AGWLDEGQLLRDAWKLKDIPGTIVHGRYDMPCPARYAWALHKAWPKADFHLIEGAGHAYSEPGILDRLIRATDKFAGK

Sequences:

>Translated_318_residues
MSSQLRSLYPEIEAVESGMLDVGDGHQVYWERSGTKGAKPAVFLHGGPGGTISPKHRRLFDPKLYDVILFDQRGCGKSTP
NASLEANTTWHLVADIERLREMAGFDTWLVFGGSWGSTLALAYAETHPDRVSELVVRGIYTLTRAELEWYYQFGVSEMFP
DKWERFLAPIPETERGDMMAAYRKRLVGSDRKAQLEAARAWSLWEGETITLLPEPETSGKFGEDDYAVAFARIENHYFVH
AGWLDEGQLLRDAWKLKDIPGTIVHGRYDMPCPARYAWALHKAWPKADFHLIEGAGHAYSEPGILDRLIRATDKFAGK
>Mature_317_residues
SSQLRSLYPEIEAVESGMLDVGDGHQVYWERSGTKGAKPAVFLHGGPGGTISPKHRRLFDPKLYDVILFDQRGCGKSTPN
ASLEANTTWHLVADIERLREMAGFDTWLVFGGSWGSTLALAYAETHPDRVSELVVRGIYTLTRAELEWYYQFGVSEMFPD
KWERFLAPIPETERGDMMAAYRKRLVGSDRKAQLEAARAWSLWEGETITLLPEPETSGKFGEDDYAVAFARIENHYFVHA
GWLDEGQLLRDAWKLKDIPGTIVHGRYDMPCPARYAWALHKAWPKADFHLIEGAGHAYSEPGILDRLIRATDKFAGK

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 35921; Mature: 35790

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQLRSLYPEIEAVESGMLDVGDGHQVYWERSGTKGAKPAVFLHGGPGGTISPKHRRLF
CCCHHHHHCCHHHHHHCCCEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHCC
DPKLYDVILFDQRGCGKSTPNASLEANTTWHLVADIERLREMAGFDTWLVFGGSWGSTLA
CCCEEEEEEECCCCCCCCCCCCCEECCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCEEE
LAYAETHPDRVSELVVRGIYTLTRAELEWYYQFGVSEMFPDKWERFLAPIPETERGDMMA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCCCCCCCHHH
AYRKRLVGSDRKAQLEAARAWSLWEGETITLLPEPETSGKFGEDDYAVAFARIENHYFVH
HHHHHHHCCCCHHHHHHHHHHEEECCCEEEEECCCCCCCCCCCCCCEEEEEEECCEEEEE
AGWLDEGQLLRDAWKLKDIPGTIVHGRYDMPCPARYAWALHKAWPKADFHLIEGAGHAYS
ECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCC
EPGILDRLIRATDKFAGK
CCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSQLRSLYPEIEAVESGMLDVGDGHQVYWERSGTKGAKPAVFLHGGPGGTISPKHRRLF
CCHHHHHCCHHHHHHCCCEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHCC
DPKLYDVILFDQRGCGKSTPNASLEANTTWHLVADIERLREMAGFDTWLVFGGSWGSTLA
CCCEEEEEEECCCCCCCCCCCCCEECCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCEEE
LAYAETHPDRVSELVVRGIYTLTRAELEWYYQFGVSEMFPDKWERFLAPIPETERGDMMA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCCCCCCCHHH
AYRKRLVGSDRKAQLEAARAWSLWEGETITLLPEPETSGKFGEDDYAVAFARIENHYFVH
HHHHHHHCCCCHHHHHHHHHHEEECCCEEEEECCCCCCCCCCCCCCEEEEEEECCEEEEE
AGWLDEGQLLRDAWKLKDIPGTIVHGRYDMPCPARYAWALHKAWPKADFHLIEGAGHAYS
ECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCC
EPGILDRLIRATDKFAGK
CCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]