Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 13476441

GI number: 13476441

Start: 6427614

End: 6428363

Strand: Direct

Name: lepB [H]

Synonym: mlr7763

Alternate gene names: 13476441

Gene position: 6427614-6428363 (Clockwise)

Preceding gene: 13476440

Following gene: 161621443

Centisome position: 91.35

GC content: 60.0

Gene sequence:

>750_bases
ATGAGCGTGGCTGAAAAATCCCAGAAGAAATCCGGCGGGCTTGGCGAAACCGTCAGCGTCATCGTCCAGGCGCTTTTGCT
CGCGCTGGTCATCCGCACGCTGTTGTTCCAGCCCTTTTCGATCCCGTCGGGATCGATGCGGCCGACGCTTCTGGAAGGCG
ACTATCTGTTCGTCACCAAATGGTCCTACGGCTATTCGCGCTATTCGCTGCCGTTCGGGCCTGACCTCTTCTCGGGCCGC
ATCTGGGGCTCCGAGCCCAAGCGCGGCGACGTTGTGGTGTTCAAGTTCCCGCCGGATCCGTCCGTCGACTACATCAAGCG
CGTGGTTGGCCTGCCCGGTGACAAGATCCAGATGAAGAATGGCCAGTTGTTCATCAACGGCGTCGGCGTGCCGCGCGTGA
AGACCGGCCAGATAGACAATCCCGATATCACCGAAATGCCTCAGCCGATCGACGTCTACCGGGAAACCCTGCCGAACGGC
GTCAGCTACGACACGCTCGACCTCAATCCGAATTCGATCGGCGACAACACGCGTGAATTCGACGTGCCGCCCGGCCACTA
TTTCATGATGGGCGACAACCGGGACAATTCCGCCGACAGCCGGTTCACCGTCGGCTATGTTCCCGCCGAGAACCTGGTTG
GCCGCGCCAACCTTGTCTTCTTCTCGATCGCCGGCAAGGCAAGCCCTCTCGAAATCTGGAAATGGCCGTCGCTGATGCGC
GTTTCGCGCCTGTTCCATTTCGTCAATTAG

Upstream 100 bases:

>100_bases
CCGTCGAACAAGCGCCACATTGATTGCATTTGACGACCGGCATTGACGTTGCCCAGCGCGCGCCGAGACTCTATACATCC
AACGCACAATCGAGGACGAC

Downstream 100 bases:

>100_bases
GGTCATGGCGGCAACAAAGCGGTTGACCGCCGATGCGCTCGCCGAAGCGCTGGTGGAACGGACGGGCCATGCCTTTGCCG
ATCGCCAGCGCCTGCAGCGC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSVAEKSQKKSGGLGETVSVIVQALLLALVIRTLLFQPFSIPSGSMRPTLLEGDYLFVTKWSYGYSRYSLPFGPDLFSGR
IWGSEPKRGDVVVFKFPPDPSVDYIKRVVGLPGDKIQMKNGQLFINGVGVPRVKTGQIDNPDITEMPQPIDVYRETLPNG
VSYDTLDLNPNSIGDNTREFDVPPGHYFMMGDNRDNSADSRFTVGYVPAENLVGRANLVFFSIAGKASPLEIWKWPSLMR
VSRLFHFVN

Sequences:

>Translated_249_residues
MSVAEKSQKKSGGLGETVSVIVQALLLALVIRTLLFQPFSIPSGSMRPTLLEGDYLFVTKWSYGYSRYSLPFGPDLFSGR
IWGSEPKRGDVVVFKFPPDPSVDYIKRVVGLPGDKIQMKNGQLFINGVGVPRVKTGQIDNPDITEMPQPIDVYRETLPNG
VSYDTLDLNPNSIGDNTREFDVPPGHYFMMGDNRDNSADSRFTVGYVPAENLVGRANLVFFSIAGKASPLEIWKWPSLMR
VSRLFHFVN
>Mature_248_residues
SVAEKSQKKSGGLGETVSVIVQALLLALVIRTLLFQPFSIPSGSMRPTLLEGDYLFVTKWSYGYSRYSLPFGPDLFSGRI
WGSEPKRGDVVVFKFPPDPSVDYIKRVVGLPGDKIQMKNGQLFINGVGVPRVKTGQIDNPDITEMPQPIDVYRETLPNGV
SYDTLDLNPNSIGDNTREFDVPPGHYFMMGDNRDNSADSRFTVGYVPAENLVGRANLVFFSIAGKASPLEIWKWPSLMRV
SRLFHFVN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=275, Percent_Identity=34.9090909090909, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 27726; Mature: 27595

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAEKSQKKSGGLGETVSVIVQALLLALVIRTLLFQPFSIPSGSMRPTLLEGDYLFVTK
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEE
WSYGYSRYSLPFGPDLFSGRIWGSEPKRGDVVVFKFPPDPSVDYIKRVVGLPGDKIQMKN
ECCCCEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEC
GQLFINGVGVPRVKTGQIDNPDITEMPQPIDVYRETLPNGVSYDTLDLNPNSIGDNTREF
CEEEEEECCCCCEECCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEE
DVPPGHYFMMGDNRDNSADSRFTVGYVPAENLVGRANLVFFSIAGKASPLEIWKWPSLMR
CCCCCEEEEEECCCCCCCCCEEEEEECCHHHHCCCCEEEEEEECCCCCCCEEECCHHHHH
VSRLFHFVN
HHHHHHHCC
>Mature Secondary Structure 
SVAEKSQKKSGGLGETVSVIVQALLLALVIRTLLFQPFSIPSGSMRPTLLEGDYLFVTK
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEE
WSYGYSRYSLPFGPDLFSGRIWGSEPKRGDVVVFKFPPDPSVDYIKRVVGLPGDKIQMKN
ECCCCEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEC
GQLFINGVGVPRVKTGQIDNPDITEMPQPIDVYRETLPNGVSYDTLDLNPNSIGDNTREF
CEEEEEECCCCCEECCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEE
DVPPGHYFMMGDNRDNSADSRFTVGYVPAENLVGRANLVFFSIAGKASPLEIWKWPSLMR
CCCCCEEEEEECCCCCCCCCEEEEEECCHHHHCCCCEEEEEEECCCCCCCEEECCHHHHH
VSRLFHFVN
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]