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The map label for this gene is acpS

Identifier: 13476440

GI number: 13476440

Start: 6427123

End: 6427536

Strand: Direct

Name: acpS

Synonym: mlr7761

Alternate gene names: 13476440

Gene position: 6427123-6427536 (Clockwise)

Preceding gene: 13476439

Following gene: 13476441

Centisome position: 91.35

GC content: 64.25

Gene sequence:

>414_bases
ATGATCATCGGCATCGGCAGCGATCTGATCGATATCAGGCGCATTGAGAACTCGCTGGAGCGTCACGGCCAGCGCTTCGT
CCAGAGGATCTATACCGAGGTCGAGCAGGCACGTTCGGAAAACCGACGAGCCCGCGCCGCTTCCTATGCCAAGCGCTTCG
CCGCCAAGGAGGCCTGCGCCAAGGCACTGGGCACCGGTCTGGCGCAAGGCGTGTTCTGGCGCGACATGGGCGTCGTCAAC
CTGCCCAGCGGCGCGCCGACCATGGCGCTGACCGGCGGCGCGCTGGCACGGCTCGAAAAAATCCTGCCCCCGGGGCACAA
GGCGGCGATCCACCTCACCATCACCGATGATTTCCCGCTCGCTCAAGCCTTTGTGATCATCGAGGCGTTGCCCGTCGAAC
AAGCGCCACATTGA

Upstream 100 bases:

>100_bases
TGAATGTCTTTCGCGAGCAGAGGCGCAAGCGGCTGGCCGAGCGCGCAAGCCGCGGTGAGCAGCCGCCCCATCCCGGTGCA
AGCATCGGTTCCGCTACGCG

Downstream 100 bases:

>100_bases
TTGCATTTGACGACCGGCATTGACGTTGCCCAGCGCGCGCCGAGACTCTATACATCCAACGCACAATCGAGGACGACATG
AGCGTGGCTGAAAAATCCCA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MIIGIGSDLIDIRRIENSLERHGQRFVQRIYTEVEQARSENRRARAASYAKRFAAKEACAKALGTGLAQGVFWRDMGVVN
LPSGAPTMALTGGALARLEKILPPGHKAAIHLTITDDFPLAQAFVIIEALPVEQAPH

Sequences:

>Translated_137_residues
MIIGIGSDLIDIRRIENSLERHGQRFVQRIYTEVEQARSENRRARAASYAKRFAAKEACAKALGTGLAQGVFWRDMGVVN
LPSGAPTMALTGGALARLEKILPPGHKAAIHLTITDDFPLAQAFVIIEALPVEQAPH
>Mature_137_residues
MIIGIGSDLIDIRRIENSLERHGQRFVQRIYTEVEQARSENRRARAASYAKRFAAKEACAKALGTGLAQGVFWRDMGVVN
LPSGAPTMALTGGALARLEKILPPGHKAAIHLTITDDFPLAQAFVIIEALPVEQAPH

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=38.28125, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_RHILO (Q985A8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_108010.1
- ProteinModelPortal:   Q985A8
- SMR:   Q985A8
- GeneID:   1230665
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr7761
- NMPDR:   fig|266835.1.peg.6111
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14927; Mature: 14927

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGSDLIDIRRIENSLERHGQRFVQRIYTEVEQARSENRRARAASYAKRFAAKEACA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLAQGVFWRDMGVVNLPSGAPTMALTGGALARLEKILPPGHKAAIHLTITDDFPL
HHHHHHHHHHHHHHCCCCEECCCCCCCEEECCHHHHHHHHHCCCCCCEEEEEEEECCCCH
AQAFVIIEALPVEQAPH
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIIGIGSDLIDIRRIENSLERHGQRFVQRIYTEVEQARSENRRARAASYAKRFAAKEACA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLAQGVFWRDMGVVNLPSGAPTMALTGGALARLEKILPPGHKAAIHLTITDDFPL
HHHHHHHHHHHHHHCCCCEECCCCCCCEEECCHHHHHHHHHCCCCCCEEEEEEEECCCCH
AQAFVIIEALPVEQAPH
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968