Click here to switch to the map view.

The map label for this gene is hisC2 [H]

Identifier: 13476421

GI number: 13476421

Start: 6407014

End: 6408126

Strand: Reverse

Name: hisC2 [H]

Synonym: mll7737

Alternate gene names: 13476421

Gene position: 6408126-6407014 (Counterclockwise)

Preceding gene: 13476422

Following gene: 13476419

Centisome position: 91.08

GC content: 64.33

Gene sequence:

>1113_bases
ATGCGTCAGCGCCCTGCCCTCTCGCCGATCATTGAAGCACTTCCCTCGACCGTGCCTTTTGTCGGCCCGGAAGCGCAGGA
GCGTGAGCGCGGGCGGGCTTTTCGTGCCCGTATCGGCGCCAATGAGAGCAGTTTTGGTCCGTCGCCGCGCGTCATCGCCC
GCATGTCCGGGATTGCCCGCGACATGTGGATGTACTGCGATCCCGACAATTTCGATCTGAAGGTCGCGGCTGCCGCGCAT
CACGACGTGGCGGTCGAGAATGTCGTTGTCGGCGAAGGCATAGACGGGCTGCTCAGCTTGGTGGCGCGCATGTATGTGGC
GCCTGGCGATGCCGTGGTCACCTCGCTCGGCGCCTATCCGACCTTCAACTTCCATGTTGCCGGCGTCGGCGGGCGGCTGG
TCACAGTCCCCTACGAGAACGACCGCGAAAGCCTGGATGATTTGCTTAAGGCGGTCGTCAAGGAGAAGGCACCGCTGGTC
TATCTGTCCAATCCGGACAATCCGATGGGCAGCTGGTGGGATGCGGACGAGGTGATCCGCTTCATCGAAGCGCTGCCGGA
GACCACCATGCTGGTGCTCGACGAGGCCTATGGCGAATTGGGGCCGGCCTCGGCCCTGCCGCCGATCGATATCTCGCGAC
CGAATGTCATCCGCATGCGAACCTTTTCAAAGGCTTACGGGCTCGCTGGGATACGCTGCGGCTATGCGATTGCCGAGGCC
CAGGTGATTCGCGACTTCGAGAAGATCCGCAACCACTATGGCGTCAGCCGCATGGCGCAGATCGCCGGCGTCGCGGCGCT
CGCCGACCAGCCCTATCTCGAGACGGTGGTGGCGCGGGTGGCAGCAGGGCGCCGGCGCATCGCGGCGATCGCCGAGCAGA
ACGGGTTGAAGCCGCTGGCCTCGGCGACCAATTTCGTCACTATCGATTGCGGCCATGACGGCGCCTTCGCGCTGAAAGTG
CTGCAAGGGCTGCTGTCGCGCGACGTCTTCATCCGCAAGCCGATGGCGCCAAAGCTCGACCGCTGCATTCGCGTCAGCGT
CGGCCTCGACCACGAACTGGATATTTTTGCCGAGGAATTGCCGGGTGCGCTGGCGGCGGCGCGGGGGAACTAG

Upstream 100 bases:

>100_bases
AGGTGACGGAATCCAGCGTTACGGCTGCAGACCGCGGAGCGCTTGCACGGCCCGGCTGGCCACGCTAGCAAGAAGTCCCT
TTTCCAAGCGAGTTCCCGCC

Downstream 100 bases:

>100_bases
GCAATTTCGCTGCGTTCGGATGTTGGCGCGCCGCTGAGCAGATTCCTGGCGCGTGCCAATATGTCCGACAATTCGGCGGC
TTCCTCATCGCCCAGGTCCG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRQRPALSPIIEALPSTVPFVGPEAQERERGRAFRARIGANESSFGPSPRVIARMSGIARDMWMYCDPDNFDLKVAAAAH
HDVAVENVVVGEGIDGLLSLVARMYVAPGDAVVTSLGAYPTFNFHVAGVGGRLVTVPYENDRESLDDLLKAVVKEKAPLV
YLSNPDNPMGSWWDADEVIRFIEALPETTMLVLDEAYGELGPASALPPIDISRPNVIRMRTFSKAYGLAGIRCGYAIAEA
QVIRDFEKIRNHYGVSRMAQIAGVAALADQPYLETVVARVAAGRRRIAAIAEQNGLKPLASATNFVTIDCGHDGAFALKV
LQGLLSRDVFIRKPMAPKLDRCIRVSVGLDHELDIFAEELPGALAAARGN

Sequences:

>Translated_370_residues
MRQRPALSPIIEALPSTVPFVGPEAQERERGRAFRARIGANESSFGPSPRVIARMSGIARDMWMYCDPDNFDLKVAAAAH
HDVAVENVVVGEGIDGLLSLVARMYVAPGDAVVTSLGAYPTFNFHVAGVGGRLVTVPYENDRESLDDLLKAVVKEKAPLV
YLSNPDNPMGSWWDADEVIRFIEALPETTMLVLDEAYGELGPASALPPIDISRPNVIRMRTFSKAYGLAGIRCGYAIAEA
QVIRDFEKIRNHYGVSRMAQIAGVAALADQPYLETVVARVAAGRRRIAAIAEQNGLKPLASATNFVTIDCGHDGAFALKV
LQGLLSRDVFIRKPMAPKLDRCIRVSVGLDHELDIFAEELPGALAAARGN
>Mature_370_residues
MRQRPALSPIIEALPSTVPFVGPEAQERERGRAFRARIGANESSFGPSPRVIARMSGIARDMWMYCDPDNFDLKVAAAAH
HDVAVENVVVGEGIDGLLSLVARMYVAPGDAVVTSLGAYPTFNFHVAGVGGRLVTVPYENDRESLDDLLKAVVKEKAPLV
YLSNPDNPMGSWWDADEVIRFIEALPETTMLVLDEAYGELGPASALPPIDISRPNVIRMRTFSKAYGLAGIRCGYAIAEA
QVIRDFEKIRNHYGVSRMAQIAGVAALADQPYLETVVARVAAGRRRIAAIAEQNGLKPLASATNFVTIDCGHDGAFALKV
LQGLLSRDVFIRKPMAPKLDRCIRVSVGLDHELDIFAEELPGALAAARGN

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=287, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322075, Length=361, Percent_Identity=22.1606648199446, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40060; Mature: 40060

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQRPALSPIIEALPSTVPFVGPEAQERERGRAFRARIGANESSFGPSPRVIARMSGIAR
CCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DMWMYCDPDNFDLKVAAAAHHDVAVENVVVGEGIDGLLSLVARMYVAPGDAVVTSLGAYP
HHEEEECCCCCCEEEEECCCCCHHHHHEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCC
TFNFHVAGVGGRLVTVPYENDRESLDDLLKAVVKEKAPLVYLSNPDNPMGSWWDADEVIR
CCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHH
FIEALPETTMLVLDEAYGELGPASALPPIDISRPNVIRMRTFSKAYGLAGIRCGYAIAEA
HHHHCCCHHEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHH
QVIRDFEKIRNHYGVSRMAQIAGVAALADQPYLETVVARVAAGRRRIAAIAEQNGLKPLA
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCHHH
SATNFVTIDCGHDGAFALKVLQGLLSRDVFIRKPMAPKLDRCIRVSVGLDHELDIFAEEL
CCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHEEEECCCCCHHHHHHHHC
PGALAAARGN
CCHHHHCCCC
>Mature Secondary Structure
MRQRPALSPIIEALPSTVPFVGPEAQERERGRAFRARIGANESSFGPSPRVIARMSGIAR
CCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DMWMYCDPDNFDLKVAAAAHHDVAVENVVVGEGIDGLLSLVARMYVAPGDAVVTSLGAYP
HHEEEECCCCCCEEEEECCCCCHHHHHEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCC
TFNFHVAGVGGRLVTVPYENDRESLDDLLKAVVKEKAPLVYLSNPDNPMGSWWDADEVIR
CCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHH
FIEALPETTMLVLDEAYGELGPASALPPIDISRPNVIRMRTFSKAYGLAGIRCGYAIAEA
HHHHCCCHHEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHH
QVIRDFEKIRNHYGVSRMAQIAGVAALADQPYLETVVARVAAGRRRIAAIAEQNGLKPLA
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCHHH
SATNFVTIDCGHDGAFALKVLQGLLSRDVFIRKPMAPKLDRCIRVSVGLDHELDIFAEEL
CCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHEEEECCCCCHHHHHHHHC
PGALAAARGN
CCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA