| Definition | Mesorhizobium loti MAFF303099 chromosome, complete genome. |
|---|---|
| Accession | NC_002678 |
| Length | 7,036,071 |
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The map label for this gene is mrcA [H]
Identifier: 13476361
GI number: 13476361
Start: 6339500
End: 6341653
Strand: Reverse
Name: mrcA [H]
Synonym: mll7657
Alternate gene names: 13476361
Gene position: 6341653-6339500 (Counterclockwise)
Preceding gene: 13476362
Following gene: 13476360
Centisome position: 90.13
GC content: 63.88
Gene sequence:
>2154_bases ATGGTCAGCCCTGAACCGCGCAAGAGAAGAGGTCCGATCGCGTCGCGCCTTCTGGCGCTGGACGCCTGGATCGATTCCTC GCTCTACGAGATCGGGTTCAAGGCGCGGCAGTTCTGGGAAGCGGCGACGATCTTCTCGCGGCGCTTTCGGCTCAAGGGCT GGCGGCGCGGCATCATCGAGATTTTGAGCGAAACTTTCACGCTCGGCGCCGGCGGCATCGTGGTGATGCTGGCGCTGGCC ATCCCGGCGTTCCAGGATACGGCCGGTGACTGGCGCGCCCAGGGCGATTTCGCCGTTACCTTCCTCGACCGCTATGGCAA CGAGATCGGCCAGCGCGGCATCATCCAGCGCGATTCCGTGCCGGTCGACGAGATGCCCGATCACGTCATCAAGGCGGTAC TGGCCACCGAGGACCGGCGTTTCTTCGACCACTACGGCATCGACGTGCTCGGCCTGTCACGCGCGATCTTCGAGAATGTG CGGGCGAACTCGGTCGTCCAGGGTGGCTCGAGCATCACTCAGCAATTGGCCAAGAACCTGTTCCTGACCAATGAGCGCAC CTTCGAGCGCAAGATCAAGGAAGCCTTCCTGTCGCTGTGGCTCGAAGCCAATCTGTCGAAGAAGGAAATCCTGCAGCTGT ATCTCGACCGCGCCTATATGGGCGGCGGCACGTTCGGCATCGAGGCGGCGGCGGACTTCTATTTCGGCAAGAGCGTCAAG GATCTTAATCTCGCCGAGGCGGCGATGCTGGCCGGCCTGTTCAAGGCGCCGACCAAATACGCCCCCCACATCAACCTGCC GGCGGCACGCGCCCGCGCCAATGTGGTGTTGTCGAACCTCGTCGATTCCGGCTTCATGACCGAAGGCCAGGTGCTGCAGG CAAGGCTGCATCCGGCCGACGTCGTCGATCGCGGCGAACAGAAAAGCCCCGACTATTTCCTCGACTGGGCCTTCGACGAG GTCAAGAAGATCGCCAAGCCGGGCCAGCATTCGCTGGTTGCCCACACTACCTTCGACGCCAACATCCAGAAGGCGGCGGA AGAGTCCGTCGAGTTCCATCTGCGCCAGTTCGGCAAGGAGTACAACGTCACCGAAGGTGCCGTGGTGGTCATCGAGACCA ATGGCGCGGTGCGGGCGATCGTCGGCGGCCGCGACTACGGCGCCAGCCAGTTCAACCGCGCCACCAAGGCGCTGCGTCAG ACCGGTTCCTCCTTCAAGCCCTATGTCTACGCCACGGCGATGGAGCACGGCTTTACGCCCAACTCAATCATTTCCGGCGG GCCAATCAGCTGGGGCAACTGGTCACCGCACAATTATAGCGGCGAGTCGGCTGGCAACATCACGCTGATCATGGCGATGG CCAAGTCGATCAACACCGTGCCGGTGCGGCTGGCCAAGGACCATCTCGGCATCGCGCCGATCAAGGCGATGGCCGAGGCG ATGGGCGTTGAATCGCCGCTCGAGTCGCACAAGACGATGGTGCTCGGCACTTCGGGCATGACCGTGATGGACCAGGCGAC GGGCTACAGCGTGTTCGCCCAGAACGGCTTTGTCGGCTCCCGGCACGGCATCACCCAGCTCGTCACCCGCACCGGCGACG TGGTGTATGACTGGACCAAGGACGCGACGCCGCCGCACCGGGTGCTGTCCGAGCAGGCACTGAAATCCATGAACACCATG CTGGCGGCCGTGCCGGTGATGGGCACGGCGCGGCGCGCGCAAATTCCCAACATCGTCGTCGCTGGCAAAACCGGCACGAC GCAATCCTACCGTGATGCCTGGTTCGTCGGCTTCACCGGCAACTACACGGCAGCCGTGTGGCTGGGCAACGACGATTTCA CCCCGACCAAGAACATGACGGGCGGCTCGCTGCCGGCGATGGTGTGGCAGCGCCTGATGGTCTACGCGCACCAGAACATC GACCTGAAGCCGATCCCCGGCATCGACAAACCTTTCGTCGACGAGGATATCGCGGCCAAGGCCGCTGAAGCGCAGAAGAA GAGCGAGGATGAAGCCGCGGCCGACGCGGCAGCCGAACGCCCGGCGGTGCTGTCCAGCCGAACCACGCAGACGCTGAGGG ACATGACGCAGCTGTTCCAGTCCGCCCCTAAACTCGACGCCGCCGCCTCGCCCGAAACGCTCTCGGCGCTGTGA
Upstream 100 bases:
>100_bases TGGGCACCCATAAAATGGATGAATAGTCACGACAGGGCGCTGCCCTGAAATTGCCGGCTTGCGGTTTTCAGGTCACGCCA CAGCCGAGCCGGGTTTTTGA
Downstream 100 bases:
>100_bases CTTCGGCCTCGGCGCGGACCAAGCCAACAGGCAAATCCATCACGCTCGCTTGCCACAAGGCCCCGCGCCGCGATATCCCC GAACGGCAATCCTTCGCGCA
Product: penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 717; Mature: 717
Protein sequence:
>717_residues MVSPEPRKRRGPIASRLLALDAWIDSSLYEIGFKARQFWEAATIFSRRFRLKGWRRGIIEILSETFTLGAGGIVVMLALA IPAFQDTAGDWRAQGDFAVTFLDRYGNEIGQRGIIQRDSVPVDEMPDHVIKAVLATEDRRFFDHYGIDVLGLSRAIFENV RANSVVQGGSSITQQLAKNLFLTNERTFERKIKEAFLSLWLEANLSKKEILQLYLDRAYMGGGTFGIEAAADFYFGKSVK DLNLAEAAMLAGLFKAPTKYAPHINLPAARARANVVLSNLVDSGFMTEGQVLQARLHPADVVDRGEQKSPDYFLDWAFDE VKKIAKPGQHSLVAHTTFDANIQKAAEESVEFHLRQFGKEYNVTEGAVVVIETNGAVRAIVGGRDYGASQFNRATKALRQ TGSSFKPYVYATAMEHGFTPNSIISGGPISWGNWSPHNYSGESAGNITLIMAMAKSINTVPVRLAKDHLGIAPIKAMAEA MGVESPLESHKTMVLGTSGMTVMDQATGYSVFAQNGFVGSRHGITQLVTRTGDVVYDWTKDATPPHRVLSEQALKSMNTM LAAVPVMGTARRAQIPNIVVAGKTGTTQSYRDAWFVGFTGNYTAAVWLGNDDFTPTKNMTGGSLPAMVWQRLMVYAHQNI DLKPIPGIDKPFVDEDIAAKAAEAQKKSEDEAAADAAAERPAVLSSRTTQTLRDMTQLFQSAPKLDAAASPETLSAL
Sequences:
>Translated_717_residues MVSPEPRKRRGPIASRLLALDAWIDSSLYEIGFKARQFWEAATIFSRRFRLKGWRRGIIEILSETFTLGAGGIVVMLALA IPAFQDTAGDWRAQGDFAVTFLDRYGNEIGQRGIIQRDSVPVDEMPDHVIKAVLATEDRRFFDHYGIDVLGLSRAIFENV RANSVVQGGSSITQQLAKNLFLTNERTFERKIKEAFLSLWLEANLSKKEILQLYLDRAYMGGGTFGIEAAADFYFGKSVK DLNLAEAAMLAGLFKAPTKYAPHINLPAARARANVVLSNLVDSGFMTEGQVLQARLHPADVVDRGEQKSPDYFLDWAFDE VKKIAKPGQHSLVAHTTFDANIQKAAEESVEFHLRQFGKEYNVTEGAVVVIETNGAVRAIVGGRDYGASQFNRATKALRQ TGSSFKPYVYATAMEHGFTPNSIISGGPISWGNWSPHNYSGESAGNITLIMAMAKSINTVPVRLAKDHLGIAPIKAMAEA MGVESPLESHKTMVLGTSGMTVMDQATGYSVFAQNGFVGSRHGITQLVTRTGDVVYDWTKDATPPHRVLSEQALKSMNTM LAAVPVMGTARRAQIPNIVVAGKTGTTQSYRDAWFVGFTGNYTAAVWLGNDDFTPTKNMTGGSLPAMVWQRLMVYAHQNI DLKPIPGIDKPFVDEDIAAKAAEAQKKSEDEAAADAAAERPAVLSSRTTQTLRDMTQLFQSAPKLDAAASPETLSAL >Mature_717_residues MVSPEPRKRRGPIASRLLALDAWIDSSLYEIGFKARQFWEAATIFSRRFRLKGWRRGIIEILSETFTLGAGGIVVMLALA IPAFQDTAGDWRAQGDFAVTFLDRYGNEIGQRGIIQRDSVPVDEMPDHVIKAVLATEDRRFFDHYGIDVLGLSRAIFENV RANSVVQGGSSITQQLAKNLFLTNERTFERKIKEAFLSLWLEANLSKKEILQLYLDRAYMGGGTFGIEAAADFYFGKSVK DLNLAEAAMLAGLFKAPTKYAPHINLPAARARANVVLSNLVDSGFMTEGQVLQARLHPADVVDRGEQKSPDYFLDWAFDE VKKIAKPGQHSLVAHTTFDANIQKAAEESVEFHLRQFGKEYNVTEGAVVVIETNGAVRAIVGGRDYGASQFNRATKALRQ TGSSFKPYVYATAMEHGFTPNSIISGGPISWGNWSPHNYSGESAGNITLIMAMAKSINTVPVRLAKDHLGIAPIKAMAEA MGVESPLESHKTMVLGTSGMTVMDQATGYSVFAQNGFVGSRHGITQLVTRTGDVVYDWTKDATPPHRVLSEQALKSMNTM LAAVPVMGTARRAQIPNIVVAGKTGTTQSYRDAWFVGFTGNYTAAVWLGNDDFTPTKNMTGGSLPAMVWQRLMVYAHQNI DLKPIPGIDKPFVDEDIAAKAAEAQKKSEDEAAADAAAERPAVLSSRTTQTLRDMTQLFQSAPKLDAAASPETLSAL
Specific function: Cell Wall Formation. Synthesis Of Cross-Linked Peptidoglycan From The Lipid Intermediates. The Enzyme Has A Penicillin-Insensitive Transglycosylase N-Terminal Domain (Formation Of Linear Glycan Strands) And A Penicillin-Sensitive Transpeptidase C-Terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=571, Percent_Identity=32.5744308231173, Blast_Score=231, Evalue=1e-61, Organism=Escherichia coli, GI1788867, Length=520, Percent_Identity=29.4230769230769, Blast_Score=191, Evalue=1e-49, Organism=Escherichia coli, GI87082258, Length=230, Percent_Identity=43.9130434782609, Blast_Score=181, Evalue=2e-46, Organism=Escherichia coli, GI1789601, Length=183, Percent_Identity=37.7049180327869, Blast_Score=117, Evalue=3e-27,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.1.129; 3.4.-.- [C]
Molecular weight: Translated: 78372; Mature: 78372
Theoretical pI: Translated: 8.02; Mature: 8.02
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVSPEPRKRRGPIASRLLALDAWIDSSLYEIGFKARQFWEAATIFSRRFRLKGWRRGIIE CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ILSETFTLGAGGIVVMLALAIPAFQDTAGDWRAQGDFAVTFLDRYGNEIGQRGIIQRDSV HHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCC PVDEMPDHVIKAVLATEDRRFFDHYGIDVLGLSRAIFENVRANSVVQGGSSITQQLAKNL CHHHCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH FLTNERTFERKIKEAFLSLWLEANLSKKEILQLYLDRAYMGGGTFGIEAAADFYFGKSVK CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC DLNLAEAAMLAGLFKAPTKYAPHINLPAARARANVVLSNLVDSGFMTEGQVLQARLHPAD CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHH VVDRGEQKSPDYFLDWAFDEVKKIAKPGQHSLVAHTTFDANIQKAAEESVEFHLRQFGKE HHCCCCCCCCCEEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCC YNVTEGAVVVIETNGAVRAIVGGRDYGASQFNRATKALRQTGSSFKPYVYATAMEHGFTP CCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCC NSIISGGPISWGNWSPHNYSGESAGNITLIMAMAKSINTVPVRLAKDHLGIAPIKAMAEA CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCEEEEECCCCCCHHHHHHHHH MGVESPLESHKTMVLGTSGMTVMDQATGYSVFAQNGFVGSRHGITQLVTRTGDVVYDWTK HCCCCHHHHCCEEEEECCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEECCC DATPPHRVLSEQALKSMNTMLAAVPVMGTARRAQIPNIVVAGKTGTTQSYRDAWFVGFTG CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCCCCEEEEEECC NYTAAVWLGNDDFTPTKNMTGGSLPAMVWQRLMVYAHQNIDLKPIPGIDKPFVDEDIAAK CEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH AAEAQKKSEDEAAADAAAERPAVLSSRTTQTLRDMTQLFQSAPKLDAAASPETLSAL HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC >Mature Secondary Structure MVSPEPRKRRGPIASRLLALDAWIDSSLYEIGFKARQFWEAATIFSRRFRLKGWRRGIIE CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ILSETFTLGAGGIVVMLALAIPAFQDTAGDWRAQGDFAVTFLDRYGNEIGQRGIIQRDSV HHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCC PVDEMPDHVIKAVLATEDRRFFDHYGIDVLGLSRAIFENVRANSVVQGGSSITQQLAKNL CHHHCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH FLTNERTFERKIKEAFLSLWLEANLSKKEILQLYLDRAYMGGGTFGIEAAADFYFGKSVK CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC DLNLAEAAMLAGLFKAPTKYAPHINLPAARARANVVLSNLVDSGFMTEGQVLQARLHPAD CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHH VVDRGEQKSPDYFLDWAFDEVKKIAKPGQHSLVAHTTFDANIQKAAEESVEFHLRQFGKE HHCCCCCCCCCEEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCC YNVTEGAVVVIETNGAVRAIVGGRDYGASQFNRATKALRQTGSSFKPYVYATAMEHGFTP CCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCC NSIISGGPISWGNWSPHNYSGESAGNITLIMAMAKSINTVPVRLAKDHLGIAPIKAMAEA CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCEEEEECCCCCCHHHHHHHHH MGVESPLESHKTMVLGTSGMTVMDQATGYSVFAQNGFVGSRHGITQLVTRTGDVVYDWTK HCCCCHHHHCCEEEEECCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHCCCEEEECCC DATPPHRVLSEQALKSMNTMLAAVPVMGTARRAQIPNIVVAGKTGTTQSYRDAWFVGFTG CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCCCCEEEEEECC NYTAAVWLGNDDFTPTKNMTGGSLPAMVWQRLMVYAHQNIDLKPIPGIDKPFVDEDIAAK CEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH AAEAQKKSEDEAAADAAAERPAVLSSRTTQTLRDMTQLFQSAPKLDAAASPETLSAL HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]