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The map label for this gene is yfcY [C]

Identifier: 13476326

GI number: 13476326

Start: 6305261

End: 6306439

Strand: Direct

Name: yfcY [C]

Synonym: mlr7614

Alternate gene names: 13476326

Gene position: 6305261-6306439 (Clockwise)

Preceding gene: 13476320

Following gene: 13476327

Centisome position: 89.61

GC content: 64.8

Gene sequence:

>1179_bases
ATGGAGACCGCCATGACCGCATGCATCGTTGGCTGGGCGCATTCGCGCTTCGGCAAGCTCGAGGGCGAGACGCTCGAAAA
CCTCATCGTCAAGGTCGCGACGGATGCGCTCGACCATGCCGGCATCGGTCCGGACGAGGTCGACGAGATCGTGCTTGGCC
ATTTCAACGCCGGCTTCTCGGCGCAGGATTTCACCGCGAGCCTGGTGCTGCAGGCCGACGACCGGCTGCGCTTCAAGCCG
GCAACGCGCGTCGAGAACGCCTGCGCGACGGGATCGGCGGCGGTCCGGCAAGGCATCCGCGCCATCGACGCCAACGCGGC
CCGCATCGTGCTGGTGGTTGGCGCCGAACAGATGACGACGACGCCGGGACCCGAGATCGGCAAGAACCTTCTGAAAGCGT
CCTATCTGCCGGAGGACGGCGAGACACCCGCGGGCTTCGCCGGCGTCTTCGGCAAGATCGCGCAGGCCTATTTCCAGCGT
TATGGCGACCAGTCCGATGCGCTCGCCATGATCGCCGCCAAGAACCACAAGAACGGCGTCGACAATCCCTATGCGCAGAT
GCGCAAGGATTTCGGCTATGATTTCTGCCGGCAGGAGAGCGAGAAGAACCCCTTCGTCGCCGGTCCTCTCAAGCGCACCG
ACTGCTCGCTGGTCTCCGACGGCGCCGCCGCTCTTATCCTCGCCGATACGGCCACTGCGCTGAAGATGCGCCGCGCAGTT
GCCTTCAGGGCCAATGAACATGTGCAGGATTTCCTGCCGATGTCGAAGCGCGATATTCTGGCCTTCGAAGGCTGCGAGCA
GGCTTGGACCCGCGCGCTGAAGAATGCCGGCGTGACGCTCGACGATCTGTCCTTTGTCGAGACGCATGACTGCTTCACCA
TTGCCGAACTGATCGAATATGAGGCCATGGGCCTGGCCAGGCCCGGCGAGGGCGCGAAGCTGGCGCTGGATGGCACGACG
GCCAAGGACGGCCGCCTTCCGGTCAACCCCTCCGGCGGGCTCAAGGCCAAGGGCCACCCGATCGGCGCCACCGGTGTCTC
CATGCATGTCCTGACCGCCATGCAGCTTGTCGGCGAAGCCGGCGGCATTCAGGTGCCGGGCGCGAAGCTTGGCGGCATCT
TCAACATGGGTGGCGCGGCGGTCGCCAACTACGTTTCCATTCTCGACCGGATCAGGTAA

Upstream 100 bases:

>100_bases
TGTCCTGTTCCGGCCCTTCACGGTCCGGGCGAGAATGTTTATCTTTGAACAATAAAGGCGAAGTGCGCCATGAGCCCAGT
ATGCTAGGCTGGCGCCAAGG

Downstream 100 bases:

>100_bases
ACCGCCCCGACATTACAGCGCCGCGCGCCTTTTGGGGTGCGCAAAGGACGCTGTAACACTTTGATTTTGCGCATGACCTC
GAGGATCGATTTCGATTTTC

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
METAMTACIVGWAHSRFGKLEGETLENLIVKVATDALDHAGIGPDEVDEIVLGHFNAGFSAQDFTASLVLQADDRLRFKP
ATRVENACATGSAAVRQGIRAIDANAARIVLVVGAEQMTTTPGPEIGKNLLKASYLPEDGETPAGFAGVFGKIAQAYFQR
YGDQSDALAMIAAKNHKNGVDNPYAQMRKDFGYDFCRQESEKNPFVAGPLKRTDCSLVSDGAAALILADTATALKMRRAV
AFRANEHVQDFLPMSKRDILAFEGCEQAWTRALKNAGVTLDDLSFVETHDCFTIAELIEYEAMGLARPGEGAKLALDGTT
AKDGRLPVNPSGGLKAKGHPIGATGVSMHVLTAMQLVGEAGGIQVPGAKLGGIFNMGGAAVANYVSILDRIR

Sequences:

>Translated_392_residues
METAMTACIVGWAHSRFGKLEGETLENLIVKVATDALDHAGIGPDEVDEIVLGHFNAGFSAQDFTASLVLQADDRLRFKP
ATRVENACATGSAAVRQGIRAIDANAARIVLVVGAEQMTTTPGPEIGKNLLKASYLPEDGETPAGFAGVFGKIAQAYFQR
YGDQSDALAMIAAKNHKNGVDNPYAQMRKDFGYDFCRQESEKNPFVAGPLKRTDCSLVSDGAAALILADTATALKMRRAV
AFRANEHVQDFLPMSKRDILAFEGCEQAWTRALKNAGVTLDDLSFVETHDCFTIAELIEYEAMGLARPGEGAKLALDGTT
AKDGRLPVNPSGGLKAKGHPIGATGVSMHVLTAMQLVGEAGGIQVPGAKLGGIFNMGGAAVANYVSILDRIR
>Mature_392_residues
METAMTACIVGWAHSRFGKLEGETLENLIVKVATDALDHAGIGPDEVDEIVLGHFNAGFSAQDFTASLVLQADDRLRFKP
ATRVENACATGSAAVRQGIRAIDANAARIVLVVGAEQMTTTPGPEIGKNLLKASYLPEDGETPAGFAGVFGKIAQAYFQR
YGDQSDALAMIAAKNHKNGVDNPYAQMRKDFGYDFCRQESEKNPFVAGPLKRTDCSLVSDGAAALILADTATALKMRRAV
AFRANEHVQDFLPMSKRDILAFEGCEQAWTRALKNAGVTLDDLSFVETHDCFTIAELIEYEAMGLARPGEGAKLALDGTT
AKDGRLPVNPSGGLKAKGHPIGATGVSMHVLTAMQLVGEAGGIQVPGAKLGGIFNMGGAAVANYVSILDRIR

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344767, Length=322, Percent_Identity=35.4037267080745, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI302344760, Length=322, Percent_Identity=35.4037267080745, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI19923233, Length=322, Percent_Identity=35.4037267080745, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI302344762, Length=242, Percent_Identity=38.4297520661157, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI55956775, Length=205, Percent_Identity=37.0731707317073, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17537653, Length=386, Percent_Identity=30.5699481865285, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19921506, Length=365, Percent_Identity=32.6027397260274, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24585051, Length=365, Percent_Identity=32.6027397260274, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 41558; Mature: 41558

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METAMTACIVGWAHSRFGKLEGETLENLIVKVATDALDHAGIGPDEVDEIVLGHFNAGFS
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
AQDFTASLVLQADDRLRFKPATRVENACATGSAAVRQGIRAIDANAARIVLVVGAEQMTT
CCCCEEEEEEECCCCEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCHHHCC
TPGPEIGKNLLKASYLPEDGETPAGFAGVFGKIAQAYFQRYGDQSDALAMIAAKNHKNGV
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
DNPYAQMRKDFGYDFCRQESEKNPFVAGPLKRTDCSLVSDGAAALILADTATALKMRRAV
CCHHHHHHHHCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHH
AFRANEHVQDFLPMSKRDILAFEGCEQAWTRALKNAGVTLDDLSFVETHDCFTIAELIEY
HHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCEECCCCHHHHCCHHHHHHHHHH
EAMGLARPGEGAKLALDGTTAKDGRLPVNPSGGLKAKGHPIGATGVSMHVLTAMQLVGEA
HHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GGIQVPGAKLGGIFNMGGAAVANYVSILDRIR
CCEECCCHHHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
METAMTACIVGWAHSRFGKLEGETLENLIVKVATDALDHAGIGPDEVDEIVLGHFNAGFS
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
AQDFTASLVLQADDRLRFKPATRVENACATGSAAVRQGIRAIDANAARIVLVVGAEQMTT
CCCCEEEEEEECCCCEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCHHHCC
TPGPEIGKNLLKASYLPEDGETPAGFAGVFGKIAQAYFQRYGDQSDALAMIAAKNHKNGV
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
DNPYAQMRKDFGYDFCRQESEKNPFVAGPLKRTDCSLVSDGAAALILADTATALKMRRAV
CCHHHHHHHHCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHH
AFRANEHVQDFLPMSKRDILAFEGCEQAWTRALKNAGVTLDDLSFVETHDCFTIAELIEY
HHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCEECCCCHHHHCCHHHHHHHHHH
EAMGLARPGEGAKLALDGTTAKDGRLPVNPSGGLKAKGHPIGATGVSMHVLTAMQLVGEA
HHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GGIQVPGAKLGGIFNMGGAAVANYVSILDRIR
CCEECCCHHHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: Acyl group transfer; Claisen condensation [C]

Inhibitor: Tris (hydroxy methyl) aminomethane [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]