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The map label for this gene is ctaD [H]

Identifier: 13476226

GI number: 13476226

Start: 6186333

End: 6187985

Strand: Direct

Name: ctaD [H]

Synonym: mlr7491

Alternate gene names: 13476226

Gene position: 6186333-6187985 (Clockwise)

Preceding gene: 13476225

Following gene: 13476227

Centisome position: 87.92

GC content: 62.79

Gene sequence:

>1653_bases
ATGGCAGACGCTGCAGCTCACGACGGCCACGACCACAAGCCTTATCATGGCTGGGTGCGCTGGGTCTATTCGACCAACCA
CAAGGACATCGGCACGCTCTACCTGATCTTCGCGATCATGGCCGGCATCATCGGCGGCGCGCTGTCGGTCGCCATCCGCA
TGGAGTTGCAGGAGCCTGGCATCCAGATCTTCAGCGGTCTGGCGCAGATGGTCTACGGCATGAACGGTGACGCCGCGATT
GATGGCGGCAAGAGCATGTACAATGCCTTCGCCACCGCGCATGCGCTGATCATGATCTTCTTCATGGTCATGCCGGCGTT
GATCGGCGGCTTCGCCAACTGGATGGTGCCGATCATGATCGGCGCGCCCGACATGGCGTTCCCGCGCATGAACAACATCT
CCTTCTGGCTGCTGCCGCCGGCCTTCATCCTGCTGCTCACCTCGATGTTCGTGCCGAGTGCGCCGGGCGCCTTCGGCGTC
GGCGGCGGCTGGACGCTCTATCCGCCGCTGTCGACCTCGGGTCAGCCCGGACCGGCCATGGATCTGGCGATCCTGTCGAT
CCACATTGCCGGTGCCTCGTCGATCCTCGGCGCCATCAACTTCATCACCACCATCTTCAACATGCGCGCTCCGGGCATGA
CGCTGCACAAGATGCCGCTGTTCGCCTGGTCGGTGCTGGTCACCGCCTTCCTGTTGCTGCTGTCCCTGCCGGTCCTGGCC
GGCGGCATCACCATGCTGCTCACCGACCGCAATTTCGGCACCACCTTCTTCGCCCCCGATGGCGGCGGCGATCCGCTGCT
GTTCCAGCACCTGTTCTGGTTCTTCGGTCATCCGGAAGTGTACATCCTGATCCTGCCGGGCTTCGGCATCATCAGCCACA
TCGTCTCGACCTTCTCGAAGAAGCCGGTGTTCGGTTATCTCGGCATGGCCTACGCCATGGTCGCGATCGGCGCCGTCGGC
TTCATCGTCTGGGCGCACCACATGTATACGACCGGCCTGTCGCTCGACACGCAGCGCTACTTCGTCTTCGCCACCATGGT
CATCGCGGTGCCGACGGGGGTGAAGATCTTCTCCTGGATCGCGACGATGTGGGGCGGGTCGATCTCGTTCAAGACGCCGA
TGCTGTGGGCGCTGGGCTTCATCTTCCTGTTCACCATCGGTGGCGTCACCGGCGTTCAGCTGGCCAATGCCGGCCTCGAC
CGCTCGCTGCATGACACCTATTTCGTCATCGCCCACTTCCACTACGTGCTGTCGCTGGGCGCGGTGTTCGCCATCTTCGC
CGGCTGGTACTACTGGTTCCCCAAGATGACCGGCTACATGTATTCGCCCGTCATCGCCAACACCCACTTCTGGGTCACCT
TTGTCGGCGTCAACCTGATCTTCTTCCCGCAGCATTTCCTTGGCCTCGCCGGCATGCCGCGCCGCACCATCGACTATCCG
GACGCGTTTGCCGGCTGGAACTACGTGTCGTCGATCGGCTCCTATATCTCGGCCGTCGGCGTGGCGATCTTCCTCTACGG
CGTGTTCGAAGCCTTCCAGAAGAAGCGCATCGCCGGTGCCAACCCATGGGGCGAGGGCGCCACCACGCTCGAATGGCAGC
TGCCTTCGCCGCCGCCGTTCCACCAGTGGGAGCAGTTGCCGAAGATCAAGTAA

Upstream 100 bases:

>100_bases
CCAACAAGACGCTGATGGCCGAGGTCGATGGCCAGAACAAGGTAGCGGCCGCCGGCAATTGATGCCGCGGGTTAGCAAGA
TTTAGGGAACGGAGCGGAAC

Downstream 100 bases:

>100_bases
GGCGGCTCCCGCCCGAATACGAAACCGCCGGCCCGCCGGCGGTTTTGGCCAACGGAATGATGGACTGAGTACGCATGGCC
CTAGTCGACGAAACCAGCAT

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MADAAAHDGHDHKPYHGWVRWVYSTNHKDIGTLYLIFAIMAGIIGGALSVAIRMELQEPGIQIFSGLAQMVYGMNGDAAI
DGGKSMYNAFATAHALIMIFFMVMPALIGGFANWMVPIMIGAPDMAFPRMNNISFWLLPPAFILLLTSMFVPSAPGAFGV
GGGWTLYPPLSTSGQPGPAMDLAILSIHIAGASSILGAINFITTIFNMRAPGMTLHKMPLFAWSVLVTAFLLLLSLPVLA
GGITMLLTDRNFGTTFFAPDGGGDPLLFQHLFWFFGHPEVYILILPGFGIISHIVSTFSKKPVFGYLGMAYAMVAIGAVG
FIVWAHHMYTTGLSLDTQRYFVFATMVIAVPTGVKIFSWIATMWGGSISFKTPMLWALGFIFLFTIGGVTGVQLANAGLD
RSLHDTYFVIAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYSPVIANTHFWVTFVGVNLIFFPQHFLGLAGMPRRTIDYP
DAFAGWNYVSSIGSYISAVGVAIFLYGVFEAFQKKRIAGANPWGEGATTLEWQLPSPPPFHQWEQLPKIK

Sequences:

>Translated_550_residues
MADAAAHDGHDHKPYHGWVRWVYSTNHKDIGTLYLIFAIMAGIIGGALSVAIRMELQEPGIQIFSGLAQMVYGMNGDAAI
DGGKSMYNAFATAHALIMIFFMVMPALIGGFANWMVPIMIGAPDMAFPRMNNISFWLLPPAFILLLTSMFVPSAPGAFGV
GGGWTLYPPLSTSGQPGPAMDLAILSIHIAGASSILGAINFITTIFNMRAPGMTLHKMPLFAWSVLVTAFLLLLSLPVLA
GGITMLLTDRNFGTTFFAPDGGGDPLLFQHLFWFFGHPEVYILILPGFGIISHIVSTFSKKPVFGYLGMAYAMVAIGAVG
FIVWAHHMYTTGLSLDTQRYFVFATMVIAVPTGVKIFSWIATMWGGSISFKTPMLWALGFIFLFTIGGVTGVQLANAGLD
RSLHDTYFVIAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYSPVIANTHFWVTFVGVNLIFFPQHFLGLAGMPRRTIDYP
DAFAGWNYVSSIGSYISAVGVAIFLYGVFEAFQKKRIAGANPWGEGATTLEWQLPSPPPFHQWEQLPKIK
>Mature_549_residues
ADAAAHDGHDHKPYHGWVRWVYSTNHKDIGTLYLIFAIMAGIIGGALSVAIRMELQEPGIQIFSGLAQMVYGMNGDAAID
GGKSMYNAFATAHALIMIFFMVMPALIGGFANWMVPIMIGAPDMAFPRMNNISFWLLPPAFILLLTSMFVPSAPGAFGVG
GGWTLYPPLSTSGQPGPAMDLAILSIHIAGASSILGAINFITTIFNMRAPGMTLHKMPLFAWSVLVTAFLLLLSLPVLAG
GITMLLTDRNFGTTFFAPDGGGDPLLFQHLFWFFGHPEVYILILPGFGIISHIVSTFSKKPVFGYLGMAYAMVAIGAVGF
IVWAHHMYTTGLSLDTQRYFVFATMVIAVPTGVKIFSWIATMWGGSISFKTPMLWALGFIFLFTIGGVTGVQLANAGLDR
SLHDTYFVIAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYSPVIANTHFWVTFVGVNLIFFPQHFLGLAGMPRRTIDYPD
AFAGWNYVSSIGSYISAVGVAIFLYGVFEAFQKKRIAGANPWGEGATTLEWQLPSPPPFHQWEQLPKIK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=528, Percent_Identity=60.0378787878788, Blast_Score=587, Evalue=1e-168,
Organism=Escherichia coli, GI1786634, Length=537, Percent_Identity=40.4096834264432, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6226519, Length=546, Percent_Identity=55.3113553113553, Blast_Score=593, Evalue=1e-170,
Organism=Saccharomyces cerevisiae, GI6226524, Length=342, Percent_Identity=59.0643274853801, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6226523, Length=267, Percent_Identity=52.059925093633, Blast_Score=256, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60243; Mature: 60111

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAAAHDGHDHKPYHGWVRWVYSTNHKDIGTLYLIFAIMAGIIGGALSVAIRMELQEPG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
IQIFSGLAQMVYGMNGDAAIDGGKSMYNAFATAHALIMIFFMVMPALIGGFANWMVPIMI
HHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
GAPDMAFPRMNNISFWLLPPAFILLLTSMFVPSAPGAFGVGGGWTLYPPLSTSGQPGPAM
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCC
DLAILSIHIAGASSILGAINFITTIFNMRAPGMTLHKMPLFAWSVLVTAFLLLLSLPVLA
EEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
GGITMLLTDRNFGTTFFAPDGGGDPLLFQHLFWFFGHPEVYILILPGFGIISHIVSTFSK
CCEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCC
KPVFGYLGMAYAMVAIGAVGFIVWAHHMYTTGLSLDTQRYFVFATMVIAVPTGVKIFSWI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
ATMWGGSISFKTPMLWALGFIFLFTIGGVTGVQLANAGLDRSLHDTYFVIAHFHYVLSLG
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AVFAIFAGWYYWFPKMTGYMYSPVIANTHFWVTFVGVNLIFFPQHFLGLAGMPRRTIDYP
HHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCC
DAFAGWNYVSSIGSYISAVGVAIFLYGVFEAFQKKRIAGANPWGEGATTLEWQLPSPPPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCC
HQWEQLPKIK
HHHHCCCCCC
>Mature Secondary Structure 
ADAAAHDGHDHKPYHGWVRWVYSTNHKDIGTLYLIFAIMAGIIGGALSVAIRMELQEPG
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
IQIFSGLAQMVYGMNGDAAIDGGKSMYNAFATAHALIMIFFMVMPALIGGFANWMVPIMI
HHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
GAPDMAFPRMNNISFWLLPPAFILLLTSMFVPSAPGAFGVGGGWTLYPPLSTSGQPGPAM
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCC
DLAILSIHIAGASSILGAINFITTIFNMRAPGMTLHKMPLFAWSVLVTAFLLLLSLPVLA
EEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
GGITMLLTDRNFGTTFFAPDGGGDPLLFQHLFWFFGHPEVYILILPGFGIISHIVSTFSK
CCEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCC
KPVFGYLGMAYAMVAIGAVGFIVWAHHMYTTGLSLDTQRYFVFATMVIAVPTGVKIFSWI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
ATMWGGSISFKTPMLWALGFIFLFTIGGVTGVQLANAGLDRSLHDTYFVIAHFHYVLSLG
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AVFAIFAGWYYWFPKMTGYMYSPVIANTHFWVTFVGVNLIFFPQHFLGLAGMPRRTIDYP
HHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCC
DAFAGWNYVSSIGSYISAVGVAIFLYGVFEAFQKKRIAGANPWGEGATTLEWQLPSPPPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCC
HQWEQLPKIK
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]