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The map label for this gene is ctaC [H]

Identifier: 13476225

GI number: 13476225

Start: 6185293

End: 6186294

Strand: Direct

Name: ctaC [H]

Synonym: mlr7490

Alternate gene names: 13476225

Gene position: 6185293-6186294 (Clockwise)

Preceding gene: 13476220

Following gene: 13476226

Centisome position: 87.91

GC content: 61.38

Gene sequence:

>1002_bases
TTGCGGAGGGAAAAAGAGTATGGTTTGAACCAGCTTGAGACTGTCGGGATTCCCGTCCCGGCATTGTTCGTTATTCTCGT
TGGCACGGCCGCGAGGAACTGGGAGACGAAGAGGGCGATGAGAAATTTCCTAGCAGACGCCAAGTTTCTAGCCAGTGCTG
GGGCTGCCACCGCGCTTTTCGCGGGCACGTCCGCCCATGCAGACCAGCCCGTGGCGTGGGAGACGACTTTCCAGGCGCCG
GCGACCGACATGATGCGGCAGATCGAATGGTTCGGGAACTACACGATGTGGTTCATCGTCCCGATCACCATTCTGGTGCT
GCTTCTCCTCGCCTACTGCATCGTCAGGTTCCGCGCGAGCGCAAACCCGGTTCCCTCCAAGACCAGCCACAACACGCTGA
TCGAGGTGATCTGGACCGTCGGCCCGGTCGTGATCCTGCTCTGCCTCGCCATCCCCTCGTTCCAGCTCCTGACTGCGCAG
TACACTCCGCCGGAAGAAGCCAAGCTGACCGTCAAGGCGACCGGCAACCAATGGAACTGGGACTACGAATACCAGACCGA
CAACACGCTCTCCTTCAATTCGGCCATCCTTCAGGATGGCGATCGCGCCAAGGCCGGCAAGGAAGACCGCAAGGTCTATC
CGCGCCTGCTCGCCGTCGACAACGAGCTGGTGGTGCCGGTCAACACGATGACGCGCGTGCTCGTCACCGCGACCGACGTG
ATCCACTCCTTCGCCATGCCGTCCTTCGGCATCAAGATCGACGCCATTCCGGGGCGCACCAACGAGACCTGGTTCAAGGC
GGAGAAGGAAGGCCTCTATTATGGTCAGTGCTCGCAGCTTTGCGGCAAGGACCACGCCTTCATGCCGATCGCCATCCGTG
TCGTCTCCGACGCGCAGTTCAAGACCTGGCTGGCTGCGGCCAAGACCGATCTGCCCGGCGCCAACAAGACGCTGATGGCC
GAGGTCGATGGCCAGAACAAGGTAGCGGCCGCCGGCAATTGA

Upstream 100 bases:

>100_bases
GGCCTGCCGAACATACGCGATTCGCCGCCATCGCCGCTGCCCCGGAAGAGCCATCTCAGCTTGCGCGCAAAAATGCCGCA
CAGTTTCCTCCGCTCCTTTC

Downstream 100 bases:

>100_bases
TGCCGCGGGTTAGCAAGATTTAGGGAACGGAGCGGAACATGGCAGACGCTGCAGCTCACGACGGCCACGACCACAAGCCT
TATCATGGCTGGGTGCGCTG

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRREKEYGLNQLETVGIPVPALFVILVGTAARNWETKRAMRNFLADAKFLASAGAATALFAGTSAHADQPVAWETTFQAP
ATDMMRQIEWFGNYTMWFIVPITILVLLLLAYCIVRFRASANPVPSKTSHNTLIEVIWTVGPVVILLCLAIPSFQLLTAQ
YTPPEEAKLTVKATGNQWNWDYEYQTDNTLSFNSAILQDGDRAKAGKEDRKVYPRLLAVDNELVVPVNTMTRVLVTATDV
IHSFAMPSFGIKIDAIPGRTNETWFKAEKEGLYYGQCSQLCGKDHAFMPIAIRVVSDAQFKTWLAAAKTDLPGANKTLMA
EVDGQNKVAAAGN

Sequences:

>Translated_333_residues
MRREKEYGLNQLETVGIPVPALFVILVGTAARNWETKRAMRNFLADAKFLASAGAATALFAGTSAHADQPVAWETTFQAP
ATDMMRQIEWFGNYTMWFIVPITILVLLLLAYCIVRFRASANPVPSKTSHNTLIEVIWTVGPVVILLCLAIPSFQLLTAQ
YTPPEEAKLTVKATGNQWNWDYEYQTDNTLSFNSAILQDGDRAKAGKEDRKVYPRLLAVDNELVVPVNTMTRVLVTATDV
IHSFAMPSFGIKIDAIPGRTNETWFKAEKEGLYYGQCSQLCGKDHAFMPIAIRVVSDAQFKTWLAAAKTDLPGANKTLMA
EVDGQNKVAAAGN
>Mature_333_residues
MRREKEYGLNQLETVGIPVPALFVILVGTAARNWETKRAMRNFLADAKFLASAGAATALFAGTSAHADQPVAWETTFQAP
ATDMMRQIEWFGNYTMWFIVPITILVLLLLAYCIVRFRASANPVPSKTSHNTLIEVIWTVGPVVILLCLAIPSFQLLTAQ
YTPPEEAKLTVKATGNQWNWDYEYQTDNTLSFNSAILQDGDRAKAGKEDRKVYPRLLAVDNELVVPVNTMTRVLVTATDV
IHSFAMPSFGIKIDAIPGRTNETWFKAEKEGLYYGQCSQLCGKDHAFMPIAIRVVSDAQFKTWLAAAKTDLPGANKTLMA
EVDGQNKVAAAGN

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RPE1 insert domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=175, Percent_Identity=41.1428571428571, Blast_Score=147, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6226540, Length=245, Percent_Identity=41.2244897959184, Blast_Score=164, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR005728 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 36781; Mature: 36781

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRREKEYGLNQLETVGIPVPALFVILVGTAARNWETKRAMRNFLADAKFLASAGAATALF
CCCCHHCCCCHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEE
AGTSAHADQPVAWETTFQAPATDMMRQIEWFGNYTMWFIVPITILVLLLLAYCIVRFRAS
ECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
ANPVPSKTSHNTLIEVIWTVGPVVILLCLAIPSFQLLTAQYTPPEEAKLTVKATGNQWNW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCC
DYEYQTDNTLSFNSAILQDGDRAKAGKEDRKVYPRLLAVDNELVVPVNTMTRVLVTATDV
EEEECCCCEEECCHHHHCCCCCCCCCCHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHH
IHSFAMPSFGIKIDAIPGRTNETWFKAEKEGLYYGQCSQLCGKDHAFMPIAIRVVSDAQF
HHHHCCCCCCEEEEECCCCCCCCCEECCCCCCEECHHHHHHCCCCCEEEEEEEEECCCHH
KTWLAAAKTDLPGANKTLMAEVDGQNKVAAAGN
HHHHHHHHCCCCCCCCEEEEEECCCCCEECCCC
>Mature Secondary Structure
MRREKEYGLNQLETVGIPVPALFVILVGTAARNWETKRAMRNFLADAKFLASAGAATALF
CCCCHHCCCCHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEE
AGTSAHADQPVAWETTFQAPATDMMRQIEWFGNYTMWFIVPITILVLLLLAYCIVRFRAS
ECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
ANPVPSKTSHNTLIEVIWTVGPVVILLCLAIPSFQLLTAQYTPPEEAKLTVKATGNQWNW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCC
DYEYQTDNTLSFNSAILQDGDRAKAGKEDRKVYPRLLAVDNELVVPVNTMTRVLVTATDV
EEEECCCCEEECCHHHHCCCCCCCCCCHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHH
IHSFAMPSFGIKIDAIPGRTNETWFKAEKEGLYYGQCSQLCGKDHAFMPIAIRVVSDAQF
HHHHCCCCCCEEEEECCCCCCCCCEECCCCCCEECHHHHHHCCCCCEEEEEEEEECCCHH
KTWLAAAKTDLPGANKTLMAEVDGQNKVAAAGN
HHHHHHHHCCCCCCCCEEEEEECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893; 11030655 [H]