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The map label for this gene is engA

Identifier: 13476158

GI number: 13476158

Start: 6120778

End: 6122217

Strand: Direct

Name: engA

Synonym: mlr7404

Alternate gene names: 13476158

Gene position: 6120778-6122217 (Clockwise)

Preceding gene: 13476157

Following gene: 13476160

Centisome position: 86.99

GC content: 64.79

Gene sequence:

>1440_bases
ATGACCTTCAAAGTCGCCATCATCGGCAGACCTAACGTCGGCAAATCGACCCTTTTCAATCGGCTGGTGGGAAGGAAGCT
GGCGCTTGTCGACGACACGCCGGGCGTCACCCGCGACCGTCGCGTCCATGCCGCTAAGCTTTACGATCTGCATTTCGACG
TCATCGACACAGCCGGTTTCGAGGATGCCGGCGCATCGACCTTGCCCGGCCGCATGCGCGCGCAGACCGAGATCGCCATC
CACGAAGCCGACCTGATCTTCTTCACCATCGACGCCAAGTCCGGCCTGCTGCCGGATGACAGGACCTTCGCCGAGATCGT
GCGCAAGTCCGGCAAGCCGGTGGTGCTGGTCGCCAACAAGGCCGAGGCCAAGGGCGCGCAGGGCGGCATGCTGGAGGCCT
GGGAACTCGGGCTGGGAGAACCGATCCCAGTTTCCGCCGAACATGGCCAGGGCATGCCCGATCTGCGCGATGCGGTGATC
GCGGCACTCGGCGAGGCGCGCGCTTTCGGTGAGGAGGAAGAGGGCGAGGACGACGAGATCGCTGCCACCGAGGTGCTGAT
CGGCGAGGATATTGCCGACCCTGACGCCGAGGATGCGCACACTTACGACAACACCAAGCCGATGCGCATCGCTGTCGTCG
GCCGCCCGAACGCCGGCAAGTCGACGCTGATCAATGCGCTGATCGGCGAGGAGCGGCTGCTGACCGGACCGGAGGCCGGC
ATCACCCGCGATTCGATTTCCGTCGACTGGGATTGGCATGGCCGTCGGCTGAAGCTGTTCGACACGGCCGGCATGCGCCG
CAAGGCGAGGATCCACGAAAAGCTCGAAGTGATGTCGGTGCAGGACGGCTTGCGCGCCATCCGCTTTGCCGAGATCGTCA
TCATCGTGCTCGACGCCACCATTCCCTTCGAGAAGCAGGATCTGCAGATCGCCGACCTGATCATTCGCGAGGGTCGCGCG
CCGGTGATCGCCTTCAACAAATGGGACCTGATAGATCATCCGCAGGAGCTGCTGGCGGAATTGCGCGAGAAGACCGAGCG
GCTGCTGCCGCAGGTGCGCGGCATCCAGGCAGTGCCGGTCTCGGCGGAGACCGGGCGCGGCCTCGACAAGCTGATGGATG
CGGTGCTGCGGACCCACAAGGTCTGGAACAGCCGCGTCTCGACCGGCAAGCTCAACCGCTGGCTGGAAGCCATACTGGCG
CATCATCCGCCGCCCGCCGTTGCCGGGCGCCGGCTCAAGGTCAAATATGTCACCCAGGCCAAGACGCGGCCGCCGGGTTT
CGTGGTCCAGTGCTCGCGTCCGGATGCGATGCCGCAATCCTATGTGCGCTATCTCTCCAACAGCCTGCGCGAAGCCTTCG
ACATGCCGGGCGTGCCGATCCGCATCGCGTTGCGCACCTCCGACAATCCTTTCGCCGGTCGAGCCAAGAAACGCGGCTGA

Upstream 100 bases:

>100_bases
GTCCGAGCTGATCCGCGGCTCAGGCAATGCCTCGTAAATGCATGTCGCCCAAAAGTGTGCAGCGGTTTTGGGACGTCGAC
ATGCATGATTGTAGGACCGT

Downstream 100 bases:

>100_bases
GCCTCGGTGCTCGTCCGATCAGGCGACCGCACGCAAGCCCGCAGTCCGCGCATTGCCCGGCAAGGCCTGCCGCGCCGCCT
CCAGCAATATGTCGGCGAGG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTFKVAIIGRPNVGKSTLFNRLVGRKLALVDDTPGVTRDRRVHAAKLYDLHFDVIDTAGFEDAGASTLPGRMRAQTEIAI
HEADLIFFTIDAKSGLLPDDRTFAEIVRKSGKPVVLVANKAEAKGAQGGMLEAWELGLGEPIPVSAEHGQGMPDLRDAVI
AALGEARAFGEEEEGEDDEIAATEVLIGEDIADPDAEDAHTYDNTKPMRIAVVGRPNAGKSTLINALIGEERLLTGPEAG
ITRDSISVDWDWHGRRLKLFDTAGMRRKARIHEKLEVMSVQDGLRAIRFAEIVIIVLDATIPFEKQDLQIADLIIREGRA
PVIAFNKWDLIDHPQELLAELREKTERLLPQVRGIQAVPVSAETGRGLDKLMDAVLRTHKVWNSRVSTGKLNRWLEAILA
HHPPPAVAGRRLKVKYVTQAKTRPPGFVVQCSRPDAMPQSYVRYLSNSLREAFDMPGVPIRIALRTSDNPFAGRAKKRG

Sequences:

>Translated_479_residues
MTFKVAIIGRPNVGKSTLFNRLVGRKLALVDDTPGVTRDRRVHAAKLYDLHFDVIDTAGFEDAGASTLPGRMRAQTEIAI
HEADLIFFTIDAKSGLLPDDRTFAEIVRKSGKPVVLVANKAEAKGAQGGMLEAWELGLGEPIPVSAEHGQGMPDLRDAVI
AALGEARAFGEEEEGEDDEIAATEVLIGEDIADPDAEDAHTYDNTKPMRIAVVGRPNAGKSTLINALIGEERLLTGPEAG
ITRDSISVDWDWHGRRLKLFDTAGMRRKARIHEKLEVMSVQDGLRAIRFAEIVIIVLDATIPFEKQDLQIADLIIREGRA
PVIAFNKWDLIDHPQELLAELREKTERLLPQVRGIQAVPVSAETGRGLDKLMDAVLRTHKVWNSRVSTGKLNRWLEAILA
HHPPPAVAGRRLKVKYVTQAKTRPPGFVVQCSRPDAMPQSYVRYLSNSLREAFDMPGVPIRIALRTSDNPFAGRAKKRG
>Mature_478_residues
TFKVAIIGRPNVGKSTLFNRLVGRKLALVDDTPGVTRDRRVHAAKLYDLHFDVIDTAGFEDAGASTLPGRMRAQTEIAIH
EADLIFFTIDAKSGLLPDDRTFAEIVRKSGKPVVLVANKAEAKGAQGGMLEAWELGLGEPIPVSAEHGQGMPDLRDAVIA
ALGEARAFGEEEEGEDDEIAATEVLIGEDIADPDAEDAHTYDNTKPMRIAVVGRPNAGKSTLINALIGEERLLTGPEAGI
TRDSISVDWDWHGRRLKLFDTAGMRRKARIHEKLEVMSVQDGLRAIRFAEIVIIVLDATIPFEKQDLQIADLIIREGRAP
VIAFNKWDLIDHPQELLAELREKTERLLPQVRGIQAVPVSAETGRGLDKLMDAVLRTHKVWNSRVSTGKLNRWLEAILAH
HPPPAVAGRRLKVKYVTQAKTRPPGFVVQCSRPDAMPQSYVRYLSNSLREAFDMPGVPIRIALRTSDNPFAGRAKKRG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=470, Percent_Identity=37.6595744680851, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI1788919, Length=177, Percent_Identity=35.5932203389831, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367268, Length=166, Percent_Identity=35.5421686746988, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_RHILO (Q986D9)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107728.1
- ProteinModelPortal:   Q986D9
- SMR:   Q986D9
- GeneID:   1230383
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr7404
- NMPDR:   fig|266835.1.peg.5829
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 52776; Mature: 52645

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKVAIIGRPNVGKSTLFNRLVGRKLALVDDTPGVTRDRRVHAAKLYDLHFDVIDTAGF
CEEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEEEEEEEEEEECCCC
EDAGASTLPGRMRAQTEIAIHEADLIFFTIDAKSGLLPDDRTFAEIVRKSGKPVVLVANK
CCCCCCCCCCCCCCCEEEEEEECEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECC
AEAKGAQGGMLEAWELGLGEPIPVSAEHGQGMPDLRDAVIAALGEARAFGEEEEGEDDEI
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
AATEVLIGEDIADPDAEDAHTYDNTKPMRIAVVGRPNAGKSTLINALIGEERLLTGPEAG
HHEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCC
ITRDSISVDWDWHGRRLKLFDTAGMRRKARIHEKLEVMSVQDGLRAIRFAEIVIIVLDAT
CCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECC
IPFEKQDLQIADLIIREGRAPVIAFNKWDLIDHPQELLAELREKTERLLPQVRGIQAVPV
CCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECC
SAETGRGLDKLMDAVLRTHKVWNSRVSTGKLNRWLEAILAHHPPPAVAGRRLKVKYVTQA
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
KTRPPGFVVQCSRPDAMPQSYVRYLSNSLREAFDMPGVPIRIALRTSDNPFAGRAKKRG
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TFKVAIIGRPNVGKSTLFNRLVGRKLALVDDTPGVTRDRRVHAAKLYDLHFDVIDTAGF
EEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEEEEEEEEEEECCCC
EDAGASTLPGRMRAQTEIAIHEADLIFFTIDAKSGLLPDDRTFAEIVRKSGKPVVLVANK
CCCCCCCCCCCCCCCEEEEEEECEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECC
AEAKGAQGGMLEAWELGLGEPIPVSAEHGQGMPDLRDAVIAALGEARAFGEEEEGEDDEI
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
AATEVLIGEDIADPDAEDAHTYDNTKPMRIAVVGRPNAGKSTLINALIGEERLLTGPEAG
HHEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCC
ITRDSISVDWDWHGRRLKLFDTAGMRRKARIHEKLEVMSVQDGLRAIRFAEIVIIVLDAT
CCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECC
IPFEKQDLQIADLIIREGRAPVIAFNKWDLIDHPQELLAELREKTERLLPQVRGIQAVPV
CCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECC
SAETGRGLDKLMDAVLRTHKVWNSRVSTGKLNRWLEAILAHHPPPAVAGRRLKVKYVTQA
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
KTRPPGFVVQCSRPDAMPQSYVRYLSNSLREAFDMPGVPIRIALRTSDNPFAGRAKKRG
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968