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The map label for this gene is mdtA [H]

Identifier: 13476125

GI number: 13476125

Start: 6086897

End: 6088051

Strand: Reverse

Name: mdtA [H]

Synonym: mll7356

Alternate gene names: 13476125

Gene position: 6088051-6086897 (Counterclockwise)

Preceding gene: 13476126

Following gene: 13476123

Centisome position: 86.53

GC content: 65.54

Gene sequence:

>1155_bases
ATGCGTAAATGGAAAATCGCTTTGGGAACGGCTGTCGCGCTAGCCGCGATCTCGGTGGCCAGCGTCCACCTGCTCGACAT
GGGCAATCTCAGGCTGAGCAGCGGCACGGCCGGTGCGGCGACGCCCGCTCCGGCGGCATTCGTCATGCCGGTGCCGGTGG
CGAACGTGGTCAAGAAGACGATCCCGATCTATCTCGACTATGCCGCCCGCATCGAGCCTATCCGCAGCATCACGCTGCAG
GCGCGCGTGCCCGGCTATTTGCAGGAACAGACGGCGCAAGACGGCGCGGATGTGCGGCAGGGCGACCTTCTGTACAGGAT
CTCGCCTGACGACTTCCAGGCCGCGCTCGACCAGGCGAAAGCCCAGGTCCAGCGCGACACGGCGACGCTCGACTATGCGC
GGTCCAATCTCGGCCGCGGCACCGAGCTCGCCAAGAGCGGTTACCTCGACAAGGACAGCTTCGACCAGCGCACCAGCACC
TTGCGCGAAGCGCAGGCGTCGCTGGCACTCAACCAGGCGGCCGTGCGCACGGCGGAGCTCAATCTGAGCTACGCCGAGAT
CCATGCTCCATTCCCCGGGCGCCTGGGCCGCAACCAGGCCTCGGTCGGAACGCTGGTCAGCGTCGCCGGCACGGTGCTCA
ACACGCTGGTGCAGCTCGACCCGATCTATGTCACCTTCAATCCGAGCGAGACGGATCTGGCCGAGATCGAGCAGGCTCGC
GCGGCCGGCCCGGTCGATGTCGAAGTCCTGCTGCCGGGTCAGACCGAGACCAGCCAGAAGGGCGAACTCACCTTCATCGA
CAACACGGTCGACCACTCGACCGGCACCATCACCGCGCGCGCCACCATCGGCAATGCGAAGTTCATGCTCATGCCCGGCC
AGTACGTGCGCGTGCGGCTGCATATCAGGCAGCAGCCTGACGCGCTGATGGTGCCGCAGACGGCGCTGGGCTCGAGCCAG
CTAGGCAAATATCTCTACGTCGTCGGCAAGGGTAATACGGTCGACCAGCGGCTGGTCTCGCTCGGCCCGACCAGCGGCGA
CCTTGTGGCCATCATGAGCGGCATCTCGGAAGGCGACCAGGTGATCACAGGCAATCTGCAGAAGATCGGGCCCGGAATGC
CGATCTCGCCACTGCCACAGAAACCGGCTACCTGA

Upstream 100 bases:

>100_bases
CCGCGGAAGCGGCGAACCCGCCTCCAAGCATACTGAACCAACTGCCGAACCCGCCTTCCCTCCCCTGGCGGAAGCGGCCG
AATAAGATTGGAGAAATATT

Downstream 100 bases:

>100_bases
CACCCCCGCAGGCCCGGTTTCCGCGCGGCGCCCTCGACCTACCCACGGGTCGTGGGCGCCGCATTTACAAGCAGGCCGAC
AAGAGCGGCGACATCGGCGC

Product: multidrug efflux membrane fusion protein MexE

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRKWKIALGTAVALAAISVASVHLLDMGNLRLSSGTAGAATPAPAAFVMPVPVANVVKKTIPIYLDYAARIEPIRSITLQ
ARVPGYLQEQTAQDGADVRQGDLLYRISPDDFQAALDQAKAQVQRDTATLDYARSNLGRGTELAKSGYLDKDSFDQRTST
LREAQASLALNQAAVRTAELNLSYAEIHAPFPGRLGRNQASVGTLVSVAGTVLNTLVQLDPIYVTFNPSETDLAEIEQAR
AAGPVDVEVLLPGQTETSQKGELTFIDNTVDHSTGTITARATIGNAKFMLMPGQYVRVRLHIRQQPDALMVPQTALGSSQ
LGKYLYVVGKGNTVDQRLVSLGPTSGDLVAIMSGISEGDQVITGNLQKIGPGMPISPLPQKPAT

Sequences:

>Translated_384_residues
MRKWKIALGTAVALAAISVASVHLLDMGNLRLSSGTAGAATPAPAAFVMPVPVANVVKKTIPIYLDYAARIEPIRSITLQ
ARVPGYLQEQTAQDGADVRQGDLLYRISPDDFQAALDQAKAQVQRDTATLDYARSNLGRGTELAKSGYLDKDSFDQRTST
LREAQASLALNQAAVRTAELNLSYAEIHAPFPGRLGRNQASVGTLVSVAGTVLNTLVQLDPIYVTFNPSETDLAEIEQAR
AAGPVDVEVLLPGQTETSQKGELTFIDNTVDHSTGTITARATIGNAKFMLMPGQYVRVRLHIRQQPDALMVPQTALGSSQ
LGKYLYVVGKGNTVDQRLVSLGPTSGDLVAIMSGISEGDQVITGNLQKIGPGMPISPLPQKPAT
>Mature_384_residues
MRKWKIALGTAVALAAISVASVHLLDMGNLRLSSGTAGAATPAPAAFVMPVPVANVVKKTIPIYLDYAARIEPIRSITLQ
ARVPGYLQEQTAQDGADVRQGDLLYRISPDDFQAALDQAKAQVQRDTATLDYARSNLGRGTELAKSGYLDKDSFDQRTST
LREAQASLALNQAAVRTAELNLSYAEIHAPFPGRLGRNQASVGTLVSVAGTVLNTLVQLDPIYVTFNPSETDLAEIEQAR
AAGPVDVEVLLPGQTETSQKGELTFIDNTVDHSTGTITARATIGNAKFMLMPGQYVRVRLHIRQQPDALMVPQTALGSSQ
LGKYLYVVGKGNTVDQRLVSLGPTSGDLVAIMSGISEGDQVITGNLQKIGPGMPISPLPQKPAT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=337, Percent_Identity=32.6409495548961, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789665, Length=336, Percent_Identity=32.4404761904762, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789929, Length=338, Percent_Identity=31.0650887573964, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786668, Length=337, Percent_Identity=31.7507418397626, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081796, Length=316, Percent_Identity=24.6835443037975, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40856; Mature: 40856

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKWKIALGTAVALAAISVASVHLLDMGNLRLSSGTAGAATPAPAAFVMPVPVANVVKKT
CCEEEEEHHHHHHHHHHHHHEEEEEECCCEEECCCCCCCCCCCCCEEEECCCHHHHHHHH
IPIYLDYAARIEPIRSITLQARVPGYLQEQTAQDGADVRQGDLLYRISPDDFQAALDQAK
CCEEEEHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHH
AQVQRDTATLDYARSNLGRGTELAKSGYLDKDSFDQRTSTLREAQASLALNQAAVRTAEL
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
NLSYAEIHAPFPGRLGRNQASVGTLVSVAGTVLNTLVQLDPIYVTFNPSETDLAEIEQAR
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
AAGPVDVEVLLPGQTETSQKGELTFIDNTVDHSTGTITARATIGNAKFMLMPGQYVRVRL
CCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCEEEEEECCCEEEEEE
HIRQQPDALMVPQTALGSSQLGKYLYVVGKGNTVDQRLVSLGPTSGDLVAIMSGISEGDQ
EEECCCCEEECCCHHCCHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHCCCCCCE
VITGNLQKIGPGMPISPLPQKPAT
EEECCHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKWKIALGTAVALAAISVASVHLLDMGNLRLSSGTAGAATPAPAAFVMPVPVANVVKKT
CCEEEEEHHHHHHHHHHHHHEEEEEECCCEEECCCCCCCCCCCCCEEEECCCHHHHHHHH
IPIYLDYAARIEPIRSITLQARVPGYLQEQTAQDGADVRQGDLLYRISPDDFQAALDQAK
CCEEEEHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHH
AQVQRDTATLDYARSNLGRGTELAKSGYLDKDSFDQRTSTLREAQASLALNQAAVRTAEL
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
NLSYAEIHAPFPGRLGRNQASVGTLVSVAGTVLNTLVQLDPIYVTFNPSETDLAEIEQAR
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
AAGPVDVEVLLPGQTETSQKGELTFIDNTVDHSTGTITARATIGNAKFMLMPGQYVRVRL
CCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCEEEEEECCCEEEEEE
HIRQQPDALMVPQTALGSSQLGKYLYVVGKGNTVDQRLVSLGPTSGDLVAIMSGISEGDQ
EEECCCCEEECCCHHCCHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHCCCCCCE
VITGNLQKIGPGMPISPLPQKPAT
EEECCHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA