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The map label for this gene is hdfR [H]

Identifier: 13476116

GI number: 13476116

Start: 6076591

End: 6077493

Strand: Direct

Name: hdfR [H]

Synonym: mlr7346

Alternate gene names: 13476116

Gene position: 6076591-6077493 (Clockwise)

Preceding gene: 13476112

Following gene: 13476124

Centisome position: 86.36

GC content: 65.89

Gene sequence:

>903_bases
ATGGATACCGAGAACCTGCGCAGTTTCCTCGAGGTCGCCGAACATGGCAGCTTCACCCTTGCGGCCGGCCGGCTCAACCT
TGCGCAATCCACCGTCAGCGCGCGGATCAGGGGGCTGGAGGAGCAGTTGGGGCGCCGGCTTTTCGTGCGCGACCGCGACG
GCGTCACGCTCACGCCGGCTGGCCGGCAGTTCCTGCCGCACGCCTCCTCCATCACCCGCACCTGGGAGCAATCCAGGCAG
GACATCGCCGTTCCCGACGGCTATGACAGCCTGCTGCGGCTGACCGCTCCCGCCTATCTGTGGGACCGTATCACCTCGCC
ATGGGTCGAGTGGATGCGCGCCAGGCGGCCGAACGTGGCGCTGCGGCTGGAAGGCAGTTTTCCGGATCTGGCCATCGACC
AACTGGCGGAAGGCCTGCTCGACATTTGCATCCTCTATCTGCCGCGCCCGCACCCCGGCATCGTCTATGAGACACTGGCC
GTCGATCAGGTCGTGCTGGTCCAGCATGCGGCGCAGACCAAGCCGTGGGCCGAAAACTACATATTGATGGACTGGGGGCT
GGAATTCCGCATCGAGCACGACCGCGCCTTTGCCGGCATGGTCAAGCCGGCGATTTCCGCGGGGCTGGTCTTCATCGGGC
TGCAGCATGTGCTGTCACGGCAGGCCGCCGCCTATCTGCCGCTCAGCGCCGTCAGCGGCCATATCGAGCGCGGCGAGATG
CGGCGCATCGACAACACGCCGGTGTTCCAGCGGCCAATCTATCTCGCCTATCCCTCGAATCCCGTCTCGTCGGATGTCCT
GGATGTCGCGCTGACGGGCTTGCGCTCGCTGGCCCGGAACTGGACCAGTGATCAGGGTTTTTCGGAAGGCGACCGTTCCC
TGGGCGTGGCCGGCCTGAGGTAG

Upstream 100 bases:

>100_bases
TGCTCTCCGGGGATCGGCCATTTAGGTCATTGTTGACCGCGACCGGAAAGCGATATTTTTTGATAGGGTCCATCGAAATT
TTCGATGCAAGGTGCAAGCC

Downstream 100 bases:

>100_bases
CCGGCCGGCGATATCTTGCTATGCCGGTTCGGTCGCGGCTGCTTTCTGCAGCCTTGCCAGCTCCGCATAGGGGATATGGC
AGCGAATCGAATGGCCGGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDTENLRSFLEVAEHGSFTLAAGRLNLAQSTVSARIRGLEEQLGRRLFVRDRDGVTLTPAGRQFLPHASSITRTWEQSRQ
DIAVPDGYDSLLRLTAPAYLWDRITSPWVEWMRARRPNVALRLEGSFPDLAIDQLAEGLLDICILYLPRPHPGIVYETLA
VDQVVLVQHAAQTKPWAENYILMDWGLEFRIEHDRAFAGMVKPAISAGLVFIGLQHVLSRQAAAYLPLSAVSGHIERGEM
RRIDNTPVFQRPIYLAYPSNPVSSDVLDVALTGLRSLARNWTSDQGFSEGDRSLGVAGLR

Sequences:

>Translated_300_residues
MDTENLRSFLEVAEHGSFTLAAGRLNLAQSTVSARIRGLEEQLGRRLFVRDRDGVTLTPAGRQFLPHASSITRTWEQSRQ
DIAVPDGYDSLLRLTAPAYLWDRITSPWVEWMRARRPNVALRLEGSFPDLAIDQLAEGLLDICILYLPRPHPGIVYETLA
VDQVVLVQHAAQTKPWAENYILMDWGLEFRIEHDRAFAGMVKPAISAGLVFIGLQHVLSRQAAAYLPLSAVSGHIERGEM
RRIDNTPVFQRPIYLAYPSNPVSSDVLDVALTGLRSLARNWTSDQGFSEGDRSLGVAGLR
>Mature_300_residues
MDTENLRSFLEVAEHGSFTLAAGRLNLAQSTVSARIRGLEEQLGRRLFVRDRDGVTLTPAGRQFLPHASSITRTWEQSRQ
DIAVPDGYDSLLRLTAPAYLWDRITSPWVEWMRARRPNVALRLEGSFPDLAIDQLAEGLLDICILYLPRPHPGIVYETLA
VDQVVLVQHAAQTKPWAENYILMDWGLEFRIEHDRAFAGMVKPAISAGLVFIGLQHVLSRQAAAYLPLSAVSGHIERGEM
RRIDNTPVFQRPIYLAYPSNPVSSDVLDVALTGLRSLARNWTSDQGFSEGDRSLGVAGLR

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=264, Percent_Identity=28.4090909090909, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788297, Length=171, Percent_Identity=29.2397660818713, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI157672245, Length=180, Percent_Identity=32.2222222222222, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787806, Length=156, Percent_Identity=32.6923076923077, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=142, Percent_Identity=33.0985915492958, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=171, Percent_Identity=31.5789473684211, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33511; Mature: 33511

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTENLRSFLEVAEHGSFTLAAGRLNLAQSTVSARIRGLEEQLGRRLFVRDRDGVTLTPA
CCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCC
GRQFLPHASSITRTWEQSRQDIAVPDGYDSLLRLTAPAYLWDRITSPWVEWMRARRPNVA
CCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEE
LRLEGSFPDLAIDQLAEGLLDICILYLPRPHPGIVYETLAVDQVVLVQHAAQTKPWAENY
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCE
ILMDWGLEFRIEHDRAFAGMVKPAISAGLVFIGLQHVLSRQAAAYLPLSAVSGHIERGEM
EEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCH
RRIDNTPVFQRPIYLAYPSNPVSSDVLDVALTGLRSLARNWTSDQGFSEGDRSLGVAGLR
HCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTENLRSFLEVAEHGSFTLAAGRLNLAQSTVSARIRGLEEQLGRRLFVRDRDGVTLTPA
CCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEECCC
GRQFLPHASSITRTWEQSRQDIAVPDGYDSLLRLTAPAYLWDRITSPWVEWMRARRPNVA
CCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEE
LRLEGSFPDLAIDQLAEGLLDICILYLPRPHPGIVYETLAVDQVVLVQHAAQTKPWAENY
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCE
ILMDWGLEFRIEHDRAFAGMVKPAISAGLVFIGLQHVLSRQAAAYLPLSAVSGHIERGEM
EEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCH
RRIDNTPVFQRPIYLAYPSNPVSSDVLDVALTGLRSLARNWTSDQGFSEGDRSLGVAGLR
HCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA