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The map label for this gene is hbpA [H]

Identifier: 13476114

GI number: 13476114

Start: 6074819

End: 6076132

Strand: Reverse

Name: hbpA [H]

Synonym: mll7343

Alternate gene names: 13476114

Gene position: 6076132-6074819 (Counterclockwise)

Preceding gene: 13476115

Following gene: 13476113

Centisome position: 86.36

GC content: 64.54

Gene sequence:

>1314_bases
TTGAAGCCGGTGCTGGCGGAAAGCTGGTCGCCGAACGCGGACGGCAGTGTCTGGACCTTCAAGCTGCGCAAGGGCGTGAA
ATTCCACAATGGCGAGGATTTCAAGGCCGACGATGTGGTGGCGACCTTCGATCGACTGGCCGACCCCAACGGCGCCTCGA
ACGCGCTTTCGGTGTTCAAGGGCCTGCTGTCGAAAGGCGGCACGCAGAAAGTCGACGACCATACCGTCGCCTTCCATCTC
GATGCGCCGAACGGCAGCTTTCCCTATTCGGTATCGATCGACAATTACAACGCCGTCATCCTGCCGGCGAGCTACAAGGG
CGATTACGAGAAGACCTTTGAGGGCACCGGGCCGTTCCGGCTCGAGAGCTACACGCCGAAGGTCGGCGCGACCTTCGTGC
GCAACGAGGACTATTGGGGCGAGAAGGCGCTGCCCGACCGGCTCGAGTTCAAATTCTACGGCGACGTGCAGCCGCGCATC
CTGGCGCTGCAGGCCGGCGAGGTCGACGTCCTCGATGCCGTACCGCTCGACGTCAGCCAGGTGGTGCTGAACAGCCCCGA
CATCACGGTGCTGCGGGTCGCCTCGACCGCGCACCGCCAGTTGCACATGCGCTGCGACACCGGTCCCTTCACCGACAAGC
GCGTGCGCCAGGCGCTGGCGCTCAGCATCGACCGCTCCAAGCTGGTCGATGGCCTGTGCCGCGGCATGGCGGCGACCGGC
AATGACAGCCCGTTCGCGCCGGCCTTTCCCGCCACCGACAAGACGGCGCCGCAGCGCGTTCAGGACATCGCCAAGGCCAA
GCAGCTCATGGAGGCGGCCGGCCTCGCCAGCGGCTTCGACATCACGCTGACGACGCTGCGCTATTCCGACATTCCAGGCT
ACGCGCAGCTGTTCCAGAATTTCGCCAAGGAGATCGGCGCCCGCATCGCGCTCAACATCGAGGATCAGGACAAATATTAC
GGCAAGGCGGTGTTCGGCCAGTCGGACTGGCTGGACAGCCCGTTGGGGATCACCGACTACGCCCACCGCAGCGTGCCGAA
CGTCTTTCTCAAGAGCCCGCTGGTCAGCGACGGCCCGTGGAATGCGGCGCATTTCAAAGACCCCGCCTATGACGGCATGG
TCACTTCCTATCTCAAGGCGCTCGACATCGGCGCGCAGCGCGCGGCGGCCTCCGACATCCAGAAACTGCTGCTCGACGAA
ACGCCGGTCATTTTCAGCTATTTCCCGGATCTGCTGGTGCCGGTGCGCAAGAATGTCAGCGGCCTGCCGCCGATCGCCGC
CGGTCTGCTGCTCGATCGCGTGTCGCTGGGATAG

Upstream 100 bases:

>100_bases
AGGCGGCGCCATCGATCCCGTCACCTATTATGACAGCGGCAGCTACCAGCTGGTTTTCCAGACCGCCGAATTCCTCTGCA
TTACGTAGCCGGATCTCACC

Downstream 100 bases:

>100_bases
AGGCTGGATTGGACAATTCCGCTTTCGGGCGGCGAGGCTATCCGCTGGCAGGCTGCGAAGAGCGATGGGGGGCCATCGTT
CGAGGGGCTCGATGCAAGGG

Product: ABC transporter binding protein

Products: NA

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKPVLAESWSPNADGSVWTFKLRKGVKFHNGEDFKADDVVATFDRLADPNGASNALSVFKGLLSKGGTQKVDDHTVAFHL
DAPNGSFPYSVSIDNYNAVILPASYKGDYEKTFEGTGPFRLESYTPKVGATFVRNEDYWGEKALPDRLEFKFYGDVQPRI
LALQAGEVDVLDAVPLDVSQVVLNSPDITVLRVASTAHRQLHMRCDTGPFTDKRVRQALALSIDRSKLVDGLCRGMAATG
NDSPFAPAFPATDKTAPQRVQDIAKAKQLMEAAGLASGFDITLTTLRYSDIPGYAQLFQNFAKEIGARIALNIEDQDKYY
GKAVFGQSDWLDSPLGITDYAHRSVPNVFLKSPLVSDGPWNAAHFKDPAYDGMVTSYLKALDIGAQRAAASDIQKLLLDE
TPVIFSYFPDLLVPVRKNVSGLPPIAAGLLLDRVSLG

Sequences:

>Translated_437_residues
MKPVLAESWSPNADGSVWTFKLRKGVKFHNGEDFKADDVVATFDRLADPNGASNALSVFKGLLSKGGTQKVDDHTVAFHL
DAPNGSFPYSVSIDNYNAVILPASYKGDYEKTFEGTGPFRLESYTPKVGATFVRNEDYWGEKALPDRLEFKFYGDVQPRI
LALQAGEVDVLDAVPLDVSQVVLNSPDITVLRVASTAHRQLHMRCDTGPFTDKRVRQALALSIDRSKLVDGLCRGMAATG
NDSPFAPAFPATDKTAPQRVQDIAKAKQLMEAAGLASGFDITLTTLRYSDIPGYAQLFQNFAKEIGARIALNIEDQDKYY
GKAVFGQSDWLDSPLGITDYAHRSVPNVFLKSPLVSDGPWNAAHFKDPAYDGMVTSYLKALDIGAQRAAASDIQKLLLDE
TPVIFSYFPDLLVPVRKNVSGLPPIAAGLLLDRVSLG
>Mature_437_residues
MKPVLAESWSPNADGSVWTFKLRKGVKFHNGEDFKADDVVATFDRLADPNGASNALSVFKGLLSKGGTQKVDDHTVAFHL
DAPNGSFPYSVSIDNYNAVILPASYKGDYEKTFEGTGPFRLESYTPKVGATFVRNEDYWGEKALPDRLEFKFYGDVQPRI
LALQAGEVDVLDAVPLDVSQVVLNSPDITVLRVASTAHRQLHMRCDTGPFTDKRVRQALALSIDRSKLVDGLCRGMAATG
NDSPFAPAFPATDKTAPQRVQDIAKAKQLMEAAGLASGFDITLTTLRYSDIPGYAQLFQNFAKEIGARIALNIEDQDKYY
GKAVFGQSDWLDSPLGITDYAHRSVPNVFLKSPLVSDGPWNAAHFKDPAYDGMVTSYLKALDIGAQRAAASDIQKLLLDE
TPVIFSYFPDLLVPVRKNVSGLPPIAAGLLLDRVSLG

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787052, Length=450, Percent_Identity=26.4444444444444, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789966, Length=308, Percent_Identity=28.8961038961039, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789887, Length=463, Percent_Identity=25.2699784017279, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787551, Length=438, Percent_Identity=25.5707762557078, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1787762, Length=434, Percent_Identity=25.1152073732719, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87081878, Length=440, Percent_Identity=24.3181818181818, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787495, Length=445, Percent_Identity=24.2696629213483, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 47670; Mature: 47670

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVLAESWSPNADGSVWTFKLRKGVKFHNGEDFKADDVVATFDRLADPNGASNALSVFK
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
GLLSKGGTQKVDDHTVAFHLDAPNGSFPYSVSIDNYNAVILPASYKGDYEKTFEGTGPFR
HHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEEECCCCCCHHHHCCCCCCEE
LESYTPKVGATFVRNEDYWGEKALPDRLEFKFYGDVQPRILALQAGEVDVLDAVPLDVSQ
ECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCEEEEECCCCCHHH
VVLNSPDITVLRVASTAHRQLHMRCDTGPFTDKRVRQALALSIDRSKLVDGLCRGMAATG
HHHCCCCEEEEEECHHHCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
NDSPFAPAFPATDKTAPQRVQDIAKAKQLMEAAGLASGFDITLTTLRYSDIPGYAQLFQN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHH
FAKEIGARIALNIEDQDKYYGKAVFGQSDWLDSPLGITDYAHRSVPNVFLKSPLVSDGPW
HHHHCCCEEEEEECCCCCHHCEEECCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCCCCCC
NAAHFKDPAYDGMVTSYLKALDIGAQRAAASDIQKLLLDETPVIFSYFPDLLVPVRKNVS
CCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
GLPPIAAGLLLDRVSLG
CCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPVLAESWSPNADGSVWTFKLRKGVKFHNGEDFKADDVVATFDRLADPNGASNALSVFK
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
GLLSKGGTQKVDDHTVAFHLDAPNGSFPYSVSIDNYNAVILPASYKGDYEKTFEGTGPFR
HHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEEECCCCCCHHHHCCCCCCEE
LESYTPKVGATFVRNEDYWGEKALPDRLEFKFYGDVQPRILALQAGEVDVLDAVPLDVSQ
ECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCEEEEECCCCCHHH
VVLNSPDITVLRVASTAHRQLHMRCDTGPFTDKRVRQALALSIDRSKLVDGLCRGMAATG
HHHCCCCEEEEEECHHHCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
NDSPFAPAFPATDKTAPQRVQDIAKAKQLMEAAGLASGFDITLTTLRYSDIPGYAQLFQN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHH
FAKEIGARIALNIEDQDKYYGKAVFGQSDWLDSPLGITDYAHRSVPNVFLKSPLVSDGPW
HHHHCCCEEEEEECCCCCHHCEEECCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCCCCCC
NAAHFKDPAYDGMVTSYLKALDIGAQRAAASDIQKLLLDETPVIFSYFPDLLVPVRKNVS
CCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
GLPPIAAGLLLDRVSLG
CCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]