BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

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The map label for this gene is kduD [H]

Identifier: 13476106

GI number: 13476106

Start: 6065976

End: 6066782

Strand: Reverse

Name: kduD [H]

Synonym: mll7334

Alternate gene names: 13476106

Gene position: 6066782-6065976 (Counterclockwise)

Preceding gene: 13476107

Following gene: 13476105

Centisome position: 86.22

GC content: 63.57

Gene sequence:

>807_bases
ATGGCGCAGCGCATACCTTCCCTGAAACGGGGAGGGCTATCGATGGATCTTTTCAAGCTGGACGGCGATGTCGCGCTGGT
CACCGGTGCCGGCAGCGGCATTGGCCAGGCAATCGCAATCGGATTGGCTGAGGCAGGAGCCGACGTCGCGTGTTTCGGTC
ATGCATCGAAAGGTGGGCTGGAAGAAACCGCGCAGCAAGTCACGACACTCGGGCGCAAGGCTTTGGTGCTGACCGGCACG
GTCACCTCGCAGAGCGATCTGGCGGCGGCAATCGATCGCGTCGAGGCCGAACTCGGTGCATTGACCGTCGCCGTCAACAA
TGCCGGCATCGCCGGTTCCGAACCGGCCGAGACCTTGTCGCTCGAGAAATGGCAGAAGGTGCACGAGGTCAACGTCGCCG
GCGTGTTCCTGTCCTGCCAGGCCGAAGCCCGCAAGATGCTGGCGCGCCGCAAGGGCTCGATCATCAACATCGCCTCGATG
TCCGGCACCATCGTCAATCGCGGATTGACGCAGGCGCACTACAACTCCTCGAAGGCCGCCGTCATCCACATGTCGAAGAG
CCTCGCCATGGAATGGGCCGATCGCGGACTGCGCGTCAATGTCGTCAGCCCCGGCTACACGCTGACGCCGATGAACAAGC
GGCCGGAGGTGGCGGAGGAGATCAAGATCTTCAAGCGCGACACGCCTATGGGACGCATGGCAGCGCCTGAGGAAATGGTC
GGGCCGACGGTGTTCCTGGCCAGCCGTGCGTCGAGCTTCGTCACCGGCCTCGACCTGATCGTCGATGGCGGCTACGTCTG
CTGGTAG

Upstream 100 bases:

>100_bases
ACGGCGTCGAGATCCCGAAAGAAGCCACGGCGGCATCGGACGGCTATTTCTAGGCATCGCTGCCCCCTGCCGGCTTGCGC
ATTGAGCGCTTGATCGAAAC

Downstream 100 bases:

>100_bases
GACCGCATCTCGCAGAACTTCGCTTGCGGTCTGAATTTGTGCATCCGCGAAGCGTTAGTCGTTGCGCGAGATGAATGTTG
GTATATATAATTTCATCCTA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAQRIPSLKRGGLSMDLFKLDGDVALVTGAGSGIGQAIAIGLAEAGADVACFGHASKGGLEETAQQVTTLGRKALVLTGT
VTSQSDLAAAIDRVEAELGALTVAVNNAGIAGSEPAETLSLEKWQKVHEVNVAGVFLSCQAEARKMLARRKGSIINIASM
SGTIVNRGLTQAHYNSSKAAVIHMSKSLAMEWADRGLRVNVVSPGYTLTPMNKRPEVAEEIKIFKRDTPMGRMAAPEEMV
GPTVFLASRASSFVTGLDLIVDGGYVCW

Sequences:

>Translated_268_residues
MAQRIPSLKRGGLSMDLFKLDGDVALVTGAGSGIGQAIAIGLAEAGADVACFGHASKGGLEETAQQVTTLGRKALVLTGT
VTSQSDLAAAIDRVEAELGALTVAVNNAGIAGSEPAETLSLEKWQKVHEVNVAGVFLSCQAEARKMLARRKGSIINIASM
SGTIVNRGLTQAHYNSSKAAVIHMSKSLAMEWADRGLRVNVVSPGYTLTPMNKRPEVAEEIKIFKRDTPMGRMAAPEEMV
GPTVFLASRASSFVTGLDLIVDGGYVCW
>Mature_267_residues
AQRIPSLKRGGLSMDLFKLDGDVALVTGAGSGIGQAIAIGLAEAGADVACFGHASKGGLEETAQQVTTLGRKALVLTGTV
TSQSDLAAAIDRVEAELGALTVAVNNAGIAGSEPAETLSLEKWQKVHEVNVAGVFLSCQAEARKMLARRKGSIINIASMS
GTIVNRGLTQAHYNSSKAAVIHMSKSLAMEWADRGLRVNVVSPGYTLTPMNKRPEVAEEIKIFKRDTPMGRMAAPEEMVG
PTVFLASRASSFVTGLDLIVDGGYVCW

Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=35.9073359073359, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=30.9803921568627, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=32.7800829875519, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=30.4, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI59889578, Length=199, Percent_Identity=34.1708542713568, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=30.3149606299213, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=31.3725490196078, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI142976729, Length=223, Percent_Identity=29.1479820627803, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=32.1428571428571, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=30, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=29.5275590551181, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4758504, Length=204, Percent_Identity=31.8627450980392, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI310128830, Length=198, Percent_Identity=26.2626262626263, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI310115468, Length=198, Percent_Identity=26.2626262626263, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=29.7619047619048, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=27.8350515463918, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI31542939, Length=214, Percent_Identity=28.5046728971963, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4503817, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI226371731, Length=214, Percent_Identity=28.5046728971963, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI83715985, Length=190, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=219, Percent_Identity=26.4840182648402, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=38.4920634920635, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=35.8565737051793, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=37.9032258064516, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.8582677165354, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=32.2709163346614, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=36.4372469635627, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=32.6848249027237, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=30.9160305343511, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.4677419354839, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789378, Length=243, Percent_Identity=34.5679012345679, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=29.9180327868852, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=26.3358778625954, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=29.5081967213115, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787526, Length=198, Percent_Identity=30.8080808080808, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=35.2, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=35.8870967741936, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=33.969465648855, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=32.7868852459016, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=30.9160305343511, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=32.1969696969697, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=29.0076335877863, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=32.1969696969697, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=30.2238805970149, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=32.1285140562249, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=30.4182509505703, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=29.8449612403101, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=31.1787072243346, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=30.9803921568627, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=29.1666666666667, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=31.2, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=30.6818181818182, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=27.8625954198473, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=216, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=27.8195488721804, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=28.6792452830189, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=29.0076335877863, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=30.1960784313725, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=30.2564102564103, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=29.4416243654822, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=204, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=26.4367816091954, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=29.6875, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997099, Length=225, Percent_Identity=28, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=31.9066147859922, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=209, Percent_Identity=30.622009569378, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193207185, Length=146, Percent_Identity=34.2465753424658, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=217, Percent_Identity=27.6497695852535, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=28.7937743190661, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=27.8947368421053, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=35.0393700787402, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=34.412955465587, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=35.6, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=35.0597609561753, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=34.375, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=34.5238095238095, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=32.2834645669291, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=36.8421052631579, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737361, Length=229, Percent_Identity=31.8777292576419, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364892, Length=202, Percent_Identity=31.1881188118812, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=32.2916666666667, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=198, Percent_Identity=30.8080808080808, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640492, Length=201, Percent_Identity=28.8557213930348, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640442, Length=210, Percent_Identity=29.5238095238095, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574402, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584744, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355631, Length=144, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076933, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584748, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011286
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.127 [H]

Molecular weight: Translated: 28099; Mature: 27968

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRIPSLKRGGLSMDLFKLDGDVALVTGAGSGIGQAIAIGLAEAGADVACFGHASKGGL
CCCCCCCHHHCCCEEEEEEECCCEEEEEECCCCCCHHHHEEHHHCCCCEEEECCCCCCCH
EETAQQVTTLGRKALVLTGTVTSQSDLAAAIDRVEAELGALTVAVNNAGIAGSEPAETLS
HHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCHHHHH
LEKWQKVHEVNVAGVFLSCQAEARKMLARRKGSIINIASMSGTIVNRGLTQAHYNSSKAA
HHHHHHHHHCEEEEEEEECCHHHHHHHHHHCCCEEEEEECCCHHHHCCCCHHHCCCCCEE
VIHMSKSLAMEWADRGLRVNVVSPGYTLTPMNKRPEVAEEIKIFKRDTPMGRMAAPEEMV
EEEEHHHHHHHHHCCCCEEEEECCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHC
GPTVFLASRASSFVTGLDLIVDGGYVCW
CCEEEEHHHHHHHHHHEEEEECCCEECC
>Mature Secondary Structure 
AQRIPSLKRGGLSMDLFKLDGDVALVTGAGSGIGQAIAIGLAEAGADVACFGHASKGGL
CCCCCCHHHCCCEEEEEEECCCEEEEEECCCCCCHHHHEEHHHCCCCEEEECCCCCCCH
EETAQQVTTLGRKALVLTGTVTSQSDLAAAIDRVEAELGALTVAVNNAGIAGSEPAETLS
HHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCHHHHH
LEKWQKVHEVNVAGVFLSCQAEARKMLARRKGSIINIASMSGTIVNRGLTQAHYNSSKAA
HHHHHHHHHCEEEEEEEECCHHHHHHHHHHCCCEEEEEECCCHHHHCCCCHHHCCCCCEE
VIHMSKSLAMEWADRGLRVNVVSPGYTLTPMNKRPEVAEEIKIFKRDTPMGRMAAPEEMV
EEEEHHHHHHHHHCCCCEEEEECCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHC
GPTVFLASRASSFVTGLDLIVDGGYVCW
CCEEEEHHHHHHHHHHEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766386 [H]