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The map label for this gene is bepF [H]

Identifier: 13476077

GI number: 13476077

Start: 6031401

End: 6032543

Strand: Direct

Name: bepF [H]

Synonym: mlr7297

Alternate gene names: 13476077

Gene position: 6031401-6032543 (Clockwise)

Preceding gene: 13476076

Following gene: 13476078

Centisome position: 85.72

GC content: 65.0

Gene sequence:

>1143_bases
GTGTCTTTGTCCCATTCCATCATCCGCCGGTTGCCGGTCGCGGGCCTTGTGGTCGCGGCGCTCGCGCTTGCCGGCTGCAG
CCAGGAGAAGGCCGAGGTCAAGGAGATAATCCGCCCGGTCAAGGTCGTCGAAATCGCTCAGGCGCATGACACCCGCATGC
TTTCCTATTCGGGATCCGTGCGGGCTCGCACCGAAAGCGCCCTGGCTTTCCGCGTCAACGGCAAGATCACCGAGCGTCTG
GTCGACATCGGTCAGCATGTGGTGCCGGGCGATGTGCTCGCCCGCATCGATCCCACCGACTACGACCTGTCGGTCAAAAG
CGCGCAGGCAGCCCTTGATGCCGCCGAACGGCAGGTCGAGACGACGGAGCTTACGCGAAAGCGCGCCGAGCAGCTTTTCA
CCAGGAACTTCGCGCCGAAATCGCAGCTCGAACAGGCGACGCTGGCCCATGACCAGGCGGTCGCCACGCGCGACTCCGCC
CGTTCGTCGCTCGACCAAGCCAAGAACCAGGTCGGCTATACCGACCTCAAGGCCGACAGGGACGGCATCGTCACGGCCGT
GAACGCCGATGTCGGCCAGGTGGTTGGCTCCGGCACGCCCGTGGTCTCAGTCGCCGTCGATGGCGAAAAGGAAGTGCTGA
TCGCGGTGCCGGAGATGGAAATCGCCGAGTTCAAGCCGGGCAAGTCAGTCAAGGCGGGCTTCTGGTCCGACAGCACGCTG
GCGCTCGACGGCAAGGTCCGCGAGGTTGCCGGCAGCGCCGATCCGCAATCGCGCACCTTCGCCGTCCGTGTCAGCCTGCC
CAATGATCCGCGTGTGCTTCTCGGCATGACCGCCAATATCGAGGCCTCGGCCGCCAACGAAAAGCAGCTGGTTTCGATCC
CCTTGAGCGCGTTGGCTGAAAAAGACAGCCAGTCGATCGTCTGGACCGTGGATCGTGGCGCCGATACCGTTCATGCCCGT
CCGGTGAAGGTTGCCAAGTTCGCCGCCGATGGCGTGCGAGTCGCAGAAGGATTGAAGCCCGGCGATATCGTGGTCGCCGC
CGGCACCCAGTTCATGACCGAGAATCTCAGGGTCAAGCTCGCCGGCGGCCTGGCGCAGCAATCAGCCTCAGCCGAGGGCG
ACGACGCCAGCCGGCTGCGCTGA

Upstream 100 bases:

>100_bases
GCCCGACGACCTGATCGACTATGCGATCAAGGCCTTGAAGAAATAGCCGGCGCCCGCCGGGCGCAGGTCGACAGTTTATC
TCCAGTTCGGGAGTGCCAAG

Downstream 100 bases:

>100_bases
GGACAGACAGGTCGGCCGCGCGTTCCCGCGGCCGCAGGTTTCCGGGCGGCGTGCGCCCGAAGGTTGAGACGTCACGGCCG
ATGTACCCCCGCATCGACCT

Product: component of multidrug efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSLSHSIIRRLPVAGLVVAALALAGCSQEKAEVKEIIRPVKVVEIAQAHDTRMLSYSGSVRARTESALAFRVNGKITERL
VDIGQHVVPGDVLARIDPTDYDLSVKSAQAALDAAERQVETTELTRKRAEQLFTRNFAPKSQLEQATLAHDQAVATRDSA
RSSLDQAKNQVGYTDLKADRDGIVTAVNADVGQVVGSGTPVVSVAVDGEKEVLIAVPEMEIAEFKPGKSVKAGFWSDSTL
ALDGKVREVAGSADPQSRTFAVRVSLPNDPRVLLGMTANIEASAANEKQLVSIPLSALAEKDSQSIVWTVDRGADTVHAR
PVKVAKFAADGVRVAEGLKPGDIVVAAGTQFMTENLRVKLAGGLAQQSASAEGDDASRLR

Sequences:

>Translated_380_residues
MSLSHSIIRRLPVAGLVVAALALAGCSQEKAEVKEIIRPVKVVEIAQAHDTRMLSYSGSVRARTESALAFRVNGKITERL
VDIGQHVVPGDVLARIDPTDYDLSVKSAQAALDAAERQVETTELTRKRAEQLFTRNFAPKSQLEQATLAHDQAVATRDSA
RSSLDQAKNQVGYTDLKADRDGIVTAVNADVGQVVGSGTPVVSVAVDGEKEVLIAVPEMEIAEFKPGKSVKAGFWSDSTL
ALDGKVREVAGSADPQSRTFAVRVSLPNDPRVLLGMTANIEASAANEKQLVSIPLSALAEKDSQSIVWTVDRGADTVHAR
PVKVAKFAADGVRVAEGLKPGDIVVAAGTQFMTENLRVKLAGGLAQQSASAEGDDASRLR
>Mature_379_residues
SLSHSIIRRLPVAGLVVAALALAGCSQEKAEVKEIIRPVKVVEIAQAHDTRMLSYSGSVRARTESALAFRVNGKITERLV
DIGQHVVPGDVLARIDPTDYDLSVKSAQAALDAAERQVETTELTRKRAEQLFTRNFAPKSQLEQATLAHDQAVATRDSAR
SSLDQAKNQVGYTDLKADRDGIVTAVNADVGQVVGSGTPVVSVAVDGEKEVLIAVPEMEIAEFKPGKSVKAGFWSDSTLA
LDGKVREVAGSADPQSRTFAVRVSLPNDPRVLLGMTANIEASAANEKQLVSIPLSALAEKDSQSIVWTVDRGADTVHARP
VKVAKFAADGVRVAEGLKPGDIVVAAGTQFMTENLRVKLAGGLAQQSASAEGDDASRLR

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=333, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789665, Length=364, Percent_Identity=24.1758241758242, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081951, Length=202, Percent_Identity=26.2376237623762, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40304; Mature: 40173

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00778 HIS_ACID_PHOSPHAT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSHSIIRRLPVAGLVVAALALAGCSQEKAEVKEIIRPVKVVEIAQAHDTRMLSYSGSV
CCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
RARTESALAFRVNGKITERLVDIGQHVVPGDVLARIDPTDYDLSVKSAQAALDAAERQVE
EEECCCEEEEEECCHHHHHHHHHCCCCCCCHHEEEECCCCCCEEHHHHHHHHHHHHHHHH
TTELTRKRAEQLFTRNFAPKSQLEQATLAHDQAVATRDSARSSLDQAKNQVGYTDLKADR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DGIVTAVNADVGQVVGSGTPVVSVAVDGEKEVLIAVPEMEIAEFKPGKSVKAGFWSDSTL
CCEEEEECCCHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCEE
ALDGKVREVAGSADPQSRTFAVRVSLPNDPRVLLGMTANIEASAANEKQLVSIPLSALAE
EECCHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEECCHHHHHC
KDSQSIVWTVDRGADTVHARPVKVAKFAADGVRVAEGLKPGDIVVAAGTQFMTENLRVKL
CCCCEEEEEEECCCCCEECCCEEHHHHHHCCHHHHCCCCCCCEEEECCCHHHHCCCEEEE
AGGLAQQSASAEGDDASRLR
ECCHHHHCCCCCCCCHHCCC
>Mature Secondary Structure 
SLSHSIIRRLPVAGLVVAALALAGCSQEKAEVKEIIRPVKVVEIAQAHDTRMLSYSGSV
CCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
RARTESALAFRVNGKITERLVDIGQHVVPGDVLARIDPTDYDLSVKSAQAALDAAERQVE
EEECCCEEEEEECCHHHHHHHHHCCCCCCCHHEEEECCCCCCEEHHHHHHHHHHHHHHHH
TTELTRKRAEQLFTRNFAPKSQLEQATLAHDQAVATRDSARSSLDQAKNQVGYTDLKADR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DGIVTAVNADVGQVVGSGTPVVSVAVDGEKEVLIAVPEMEIAEFKPGKSVKAGFWSDSTL
CCEEEEECCCHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCEE
ALDGKVREVAGSADPQSRTFAVRVSLPNDPRVLLGMTANIEASAANEKQLVSIPLSALAE
EECCHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEECCHHHHHC
KDSQSIVWTVDRGADTVHARPVKVAKFAADGVRVAEGLKPGDIVVAAGTQFMTENLRVKL
CCCCEEEEEEECCCCCEECCCEEHHHHHHCCHHHHCCCCCCCEEEECCCHHHHCCCEEEE
AGGLAQQSASAEGDDASRLR
ECCHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]