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The map label for this gene is kbaZ [H]

Identifier: 13476010

GI number: 13476010

Start: 5956639

End: 5957922

Strand: Reverse

Name: kbaZ [H]

Synonym: mll7215

Alternate gene names: 13476010

Gene position: 5957922-5956639 (Counterclockwise)

Preceding gene: 13476011

Following gene: 13476009

Centisome position: 84.68

GC content: 66.9

Gene sequence:

>1284_bases
ATGAGCCAGGCGACGGACAGGCTGGCGGCCATCGCGACGCGTCGTGCGGCCGGCGAACGCTGCGGCATCGCCTCGATCTG
CTCGGCCCATCCGCTGGTCATCGAAGCGGCGCTGCGCCATGGCAAGGCGCGCGATGCCGACGTGCTGATCGAGGCCACCT
GCAACCAGGTGAACCATGAAGGCGGCTACACCGGCATGACACCAGGGGATTTCCGCGGCTTCGTCGAGACGATCGCCGGC
AAGATCGGCTTTTCCCTCGACAGGCTGATGCTCGGCGGCGACCATCTCGGCCCCAATCCGTGGAAGCATCTGCCGGCGCC
CGAGGCCATGGCCAAGGCTTCGCGCATGGTCGACGCCTATGCCGAGGCCGGCTTCACCAAGATTCATCTCGACGCCAGCA
TGGGTTGCGCCGGCGAAGGCGCCGCGCCGCCCGATGCGACGATCGCCGCGCGCGCCGCCGAACTGGCCGAGGTGGCGGAG
GCCGCCGCCGAACGAATGGGCGGCACAAAGCCTGTCTATGTCATCGGCACCGAAGTGCCGGTGCCGGGCGGCGCCCTGGA
AGCGATGGACCATCTGGCGGTGACGACGCCCGAGGCGCCACGAGAGACGGTTCGCATCCACCGCGATGCCTTCAGCCAGC
GAGGCCTCGACCAGGCCTTTTCGCGGGCGCTCGGTGTCGTCGTGCAGCCGGGTGTCGAATTTGGCAATGCCGAGGTGATC
ACCTATAAACCGGAACGCGCCCGTGCATTGGCCGGCACGTTGCGGGATCTGCCGCAATTCGTCTTCGAGGCGCATTCGAC
CGATTACCAGCCGGCCTCGGCTTTGAGTGCGCTGGTCGATGACGGCTTCGCCATACTCAAGGTCGGGCCGTGGCTGACCT
TCGCGCTGCGTGAAGCGCTCTATGGCCTGAGCCACATCGCCGACATTCTGGCTCCCGATCCGGCGCGCGAAAGCCTGCCG
GCGGCGATGGAGCGCGTGATGCTGGCAGCACCGGGCAATTGGAAGAACTACTATCACGGCTCGGAGACCGAACAGCGCAT
CGAACGCCATTTCTCCTACAGCGACCGCATCCGCTACTACTGGCCGGCGCCTGCAGCCCGGCAGGCCACCGACGCGCTGA
TGCAGGCGCTCGGCGACCGCGACATCCCCCTGCCCCTCATCAGCCAGTATCTCGGCCGCCTGAACGGTGCGGTGGCGAAC
GGTTCGGTTGCGCCAAAAGCCGGGGAGTTGTTGATCGCCAGCGTGACAGAGGTTCTCGACATCTTCGCCAGCGCAACCGG
CTGA

Upstream 100 bases:

>100_bases
GCGGCGCGCTGGCGGTGACCAGGAAGGGACCGATGGAGGGCATCGCCTCGCTTGCCGCGGTCGAGGCCTACGTCGCGACC
GCCAGAACCGGAGCGCCGGC

Downstream 100 bases:

>100_bases
TCGGCCGGGCTTCATTATCAGACCGGCGCCCAGTCGCCGTCGCCTCGGCCTTCCCGCTGGTGTGGATGGTGCTGTCGAGC
CTGAAAACCCCGGCCGAGAG

Product: tagatose 6-phosphate kinase agaz

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSQATDRLAAIATRRAAGERCGIASICSAHPLVIEAALRHGKARDADVLIEATCNQVNHEGGYTGMTPGDFRGFVETIAG
KIGFSLDRLMLGGDHLGPNPWKHLPAPEAMAKASRMVDAYAEAGFTKIHLDASMGCAGEGAAPPDATIAARAAELAEVAE
AAAERMGGTKPVYVIGTEVPVPGGALEAMDHLAVTTPEAPRETVRIHRDAFSQRGLDQAFSRALGVVVQPGVEFGNAEVI
TYKPERARALAGTLRDLPQFVFEAHSTDYQPASALSALVDDGFAILKVGPWLTFALREALYGLSHIADILAPDPARESLP
AAMERVMLAAPGNWKNYYHGSETEQRIERHFSYSDRIRYYWPAPAARQATDALMQALGDRDIPLPLISQYLGRLNGAVAN
GSVAPKAGELLIASVTEVLDIFASATG

Sequences:

>Translated_427_residues
MSQATDRLAAIATRRAAGERCGIASICSAHPLVIEAALRHGKARDADVLIEATCNQVNHEGGYTGMTPGDFRGFVETIAG
KIGFSLDRLMLGGDHLGPNPWKHLPAPEAMAKASRMVDAYAEAGFTKIHLDASMGCAGEGAAPPDATIAARAAELAEVAE
AAAERMGGTKPVYVIGTEVPVPGGALEAMDHLAVTTPEAPRETVRIHRDAFSQRGLDQAFSRALGVVVQPGVEFGNAEVI
TYKPERARALAGTLRDLPQFVFEAHSTDYQPASALSALVDDGFAILKVGPWLTFALREALYGLSHIADILAPDPARESLP
AAMERVMLAAPGNWKNYYHGSETEQRIERHFSYSDRIRYYWPAPAARQATDALMQALGDRDIPLPLISQYLGRLNGAVAN
GSVAPKAGELLIASVTEVLDIFASATG
>Mature_426_residues
SQATDRLAAIATRRAAGERCGIASICSAHPLVIEAALRHGKARDADVLIEATCNQVNHEGGYTGMTPGDFRGFVETIAGK
IGFSLDRLMLGGDHLGPNPWKHLPAPEAMAKASRMVDAYAEAGFTKIHLDASMGCAGEGAAPPDATIAARAAELAEVAEA
AAERMGGTKPVYVIGTEVPVPGGALEAMDHLAVTTPEAPRETVRIHRDAFSQRGLDQAFSRALGVVVQPGVEFGNAEVIT
YKPERARALAGTLRDLPQFVFEAHSTDYQPASALSALVDDGFAILKVGPWLTFALREALYGLSHIADILAPDPARESLPA
AMERVMLAAPGNWKNYYHGSETEQRIERHFSYSDRIRYYWPAPAARQATDALMQALGDRDIPLPLISQYLGRLNGAVANG
SVAPKAGELLIASVTEVLDIFASATG

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=421, Percent_Identity=49.4061757719715, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1788411, Length=412, Percent_Identity=47.3300970873786, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 45417; Mature: 45286

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQATDRLAAIATRRAAGERCGIASICSAHPLVIEAALRHGKARDADVLIEATCNQVNHE
CCCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
GGYTGMTPGDFRGFVETIAGKIGFSLDRLMLGGDHLGPNPWKHLPAPEAMAKASRMVDAY
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AEAGFTKIHLDASMGCAGEGAAPPDATIAARAAELAEVAEAAAERMGGTKPVYVIGTEVP
HHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
VPGGALEAMDHLAVTTPEAPRETVRIHRDAFSQRGLDQAFSRALGVVVQPGVEFGNAEVI
CCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCEEECCCCCCCCEEEE
TYKPERARALAGTLRDLPQFVFEAHSTDYQPASALSALVDDGFAILKVGPWLTFALREAL
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHH
YGLSHIADILAPDPARESLPAAMERVMLAAPGNWKNYYHGSETEQRIERHFSYSDRIRYY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEE
WPAPAARQATDALMQALGDRDIPLPLISQYLGRLNGAVANGSVAPKAGELLIASVTEVLD
ECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IFASATG
HHHHCCC
>Mature Secondary Structure 
SQATDRLAAIATRRAAGERCGIASICSAHPLVIEAALRHGKARDADVLIEATCNQVNHE
CCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
GGYTGMTPGDFRGFVETIAGKIGFSLDRLMLGGDHLGPNPWKHLPAPEAMAKASRMVDAY
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AEAGFTKIHLDASMGCAGEGAAPPDATIAARAAELAEVAEAAAERMGGTKPVYVIGTEVP
HHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
VPGGALEAMDHLAVTTPEAPRETVRIHRDAFSQRGLDQAFSRALGVVVQPGVEFGNAEVI
CCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCEEECCCCCCCCEEEE
TYKPERARALAGTLRDLPQFVFEAHSTDYQPASALSALVDDGFAILKVGPWLTFALREAL
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHH
YGLSHIADILAPDPARESLPAAMERVMLAAPGNWKNYYHGSETEQRIERHFSYSDRIRYY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEE
WPAPAARQATDALMQALGDRDIPLPLISQYLGRLNGAVANGSVAPKAGELLIASVTEVLD
ECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IFASATG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA