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The map label for this gene is aaeR [H]

Identifier: 13475966

GI number: 13475966

Start: 5914829

End: 5915731

Strand: Direct

Name: aaeR [H]

Synonym: mlr7163

Alternate gene names: 13475966

Gene position: 5914829-5915731 (Clockwise)

Preceding gene: 13475959

Following gene: 13475967

Centisome position: 84.06

GC content: 67.77

Gene sequence:

>903_bases
ATGGATAGGCTCGAGAGCATGGCCGTGTTCGTCAAGGCGGTCGACCTTGGCTCGTTCGCGGCTGCTGCGGTCGCGCTCGA
CCTGTCCGGGCCGATGGTTGGCAAGCATGTCCGCTTTCTCGAAGATCGGCTGGGGGTGCGCCTCATCAACCGCACCACGC
GCCGCCAGAGCCTGACCGATTTCGGCCGCGCCTATTACGAACGCTGCCGGGTCGTGCTGGCCGAGGCGGAAGCGGCCGAG
GCGCTCGCCGCCGACCAGTTCTCGGAACCGAGAGGCAGACTGCGCGTGACCATGCCGGCGCATTTCGGCCGCCACTGCGT
CACCCCCGTGCTGCTGAAACTGGCGCGGCACTATCCGATGCTGGAACTCGACCTGTCACTCAGCGACCGCTTCGCCGATC
TCGCCGAAGACGGCTTTGACCTCGCCATCCGCACCGGCGACCTGGAGGACAAGGCCGGCGTGATCGCGCGCCGCGTTGCG
CGCCAGGGTATGGTCGTCTGCGCCGCGCCCGCCTATCTCAGACGTCACGGTGAGCCACGGCGGATCGAAGACCTCGCCGA
CCATCAGGCAATCGTCTACCGCCGGCTCGGCCAGGTCGTTCAACCCTGGCTGTTTGCGCGCGAAGGGCAGCCAGCGCAGG
AGATCGTCCCCAGCGGTCGCCTGCGGCTCGACGATCTCGATGCCATCGCCGACGCAGCGGTCGACGGCATGGGGTTGGCG
TGGCTACCTTATTGGCTGGTTCGCGAACGCATCCAGGCCGGCGCGCTGGTCGCACTGGTGCCGGGCCAGCCGCGCTATCC
CTACGACTGCCACGCCCTTTGGCTGCAGACGCCACATTTGCCGCTCAAGGTGCGGCTCGCCGTCGATGCGCTGGCGGCCG
CTTTGCCGAAACTGATGGGCTGA

Upstream 100 bases:

>100_bases
GGGTTACTCCAAATTATCTGAACCGAATGAGCTATGCAGCCAAAGGCTTCATGGATAAATGGGCGTAGGGATAAAGCAGT
AGAAACCAGAGGTTTCGAAT

Downstream 100 bases:

>100_bases
TCGCAAACAGAGCAGGCTTGCGCTCTTTGCGGCGTCGCCTTCCCTGCCATATTAAGGTGGCTGACTGAATGTGCGCATTG
CAGGAGAGGCGGTTCATGAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDRLESMAVFVKAVDLGSFAAAAVALDLSGPMVGKHVRFLEDRLGVRLINRTTRRQSLTDFGRAYYERCRVVLAEAEAAE
ALAADQFSEPRGRLRVTMPAHFGRHCVTPVLLKLARHYPMLELDLSLSDRFADLAEDGFDLAIRTGDLEDKAGVIARRVA
RQGMVVCAAPAYLRRHGEPRRIEDLADHQAIVYRRLGQVVQPWLFAREGQPAQEIVPSGRLRLDDLDAIADAAVDGMGLA
WLPYWLVRERIQAGALVALVPGQPRYPYDCHALWLQTPHLPLKVRLAVDALAAALPKLMG

Sequences:

>Translated_300_residues
MDRLESMAVFVKAVDLGSFAAAAVALDLSGPMVGKHVRFLEDRLGVRLINRTTRRQSLTDFGRAYYERCRVVLAEAEAAE
ALAADQFSEPRGRLRVTMPAHFGRHCVTPVLLKLARHYPMLELDLSLSDRFADLAEDGFDLAIRTGDLEDKAGVIARRVA
RQGMVVCAAPAYLRRHGEPRRIEDLADHQAIVYRRLGQVVQPWLFAREGQPAQEIVPSGRLRLDDLDAIADAAVDGMGLA
WLPYWLVRERIQAGALVALVPGQPRYPYDCHALWLQTPHLPLKVRLAVDALAAALPKLMG
>Mature_300_residues
MDRLESMAVFVKAVDLGSFAAAAVALDLSGPMVGKHVRFLEDRLGVRLINRTTRRQSLTDFGRAYYERCRVVLAEAEAAE
ALAADQFSEPRGRLRVTMPAHFGRHCVTPVLLKLARHYPMLELDLSLSDRFADLAEDGFDLAIRTGDLEDKAGVIARRVA
RQGMVVCAAPAYLRRHGEPRRIEDLADHQAIVYRRLGQVVQPWLFAREGQPAQEIVPSGRLRLDDLDAIADAAVDGMGLA
WLPYWLVRERIQAGALVALVPGQPRYPYDCHALWLQTPHLPLKVRLAVDALAAALPKLMG

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=34.1216216216216, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=33.2225913621262, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789440, Length=296, Percent_Identity=28.3783783783784, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=32.8719723183391, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787128, Length=254, Percent_Identity=31.496062992126, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786401, Length=256, Percent_Identity=32.03125, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787589, Length=280, Percent_Identity=28.9285714285714, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788481, Length=275, Percent_Identity=26.5454545454545, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786448, Length=274, Percent_Identity=29.5620437956204, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789173, Length=256, Percent_Identity=25.78125, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33314; Mature: 33314

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLESMAVFVKAVDLGSFAAAAVALDLSGPMVGKHVRFLEDRLGVRLINRTTRRQSLTD
CCHHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGRAYYERCRVVLAEAEAAEALAADQFSEPRGRLRVTMPAHFGRHCVTPVLLKLARHYPM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHCCHHHHHHHHHHHHHCCCE
LELDLSLSDRFADLAEDGFDLAIRTGDLEDKAGVIARRVARQGMVVCAAPAYLRRHGEPR
EEEECCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCC
RIEDLADHQAIVYRRLGQVVQPWLFAREGQPAQEIVPSGRLRLDDLDAIADAAVDGMGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEHHHHHHHHHHHCCCCHH
WLPYWLVRERIQAGALVALVPGQPRYPYDCHALWLQTPHLPLKVRLAVDALAAALPKLMG
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRLESMAVFVKAVDLGSFAAAAVALDLSGPMVGKHVRFLEDRLGVRLINRTTRRQSLTD
CCHHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGRAYYERCRVVLAEAEAAEALAADQFSEPRGRLRVTMPAHFGRHCVTPVLLKLARHYPM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHCCHHHHHHHHHHHHHCCCE
LELDLSLSDRFADLAEDGFDLAIRTGDLEDKAGVIARRVARQGMVVCAAPAYLRRHGEPR
EEEECCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCC
RIEDLADHQAIVYRRLGQVVQPWLFAREGQPAQEIVPSGRLRLDDLDAIADAAVDGMGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEHHHHHHHHHHHCCCCHH
WLPYWLVRERIQAGALVALVPGQPRYPYDCHALWLQTPHLPLKVRLAVDALAAALPKLMG
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]