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The map label for this gene is qorA [H]

Identifier: 13475965

GI number: 13475965

Start: 5913737

End: 5914726

Strand: Reverse

Name: qorA [H]

Synonym: mll7162

Alternate gene names: 13475965

Gene position: 5914726-5913737 (Counterclockwise)

Preceding gene: 13475968

Following gene: 13475964

Centisome position: 84.06

GC content: 63.84

Gene sequence:

>990_bases
ATGGCTCGTATTGTCCGCTTCCACCAGCATGGCGGTCCCGAAGTCCTGGGCATCGAGGATATCGACCTTCCTCCACCGGC
TCCAGGCGAGGTTCAAATCCGCGTCAAGGCGCTCGGCCTCAATCGCGCCGAGGCGCTGCTGCGCGCGGGCAGCTATATCG
AGACTCCGCCCCTGCCCTCCGGACTTGGTCTCGAGGCGGCGGGGGTTGTCGAAACAGTCGGCGAAGGCGTGAAGGATTTC
GTCCCGGGCGACGCTGTCAGCGTCATCCCGCCGCAATCGATGGTGTGCTGGCCGGCTTACGGCGAGGTGGTCGCCTATCC
CGCCGGGCTCATCGTCAAGCACCCATCGTCGCTCGACTGGCAGACAGCGGCGGCTGTCTGGATGCAATATCTCACCGCCT
ATGGCGCCCTGATCGACATCGCCAGACTGAGCAGCGGAGACGCTGTCGTCATCACCGCGGCCTCAAGCAGCGTCGGGCTT
GCCGCGATCCAGATCGCCAACAAAATTGGCGCGACAGCGATCGCGGTGACGCGAACGTCGGTAAAGAAACAGGCCTTGCT
CGACGCCGGCGCGGCGCATGTTGTGGTCCTGGCCGAGGAGGATCTCGCTGCACGGCTGAGCGAGATCGCGGGACCGCAAG
CCGTGCGCGTCGTGCTCGATGCAATCGGCGGCCCAATCTTCGAGCCGCTGACGGCGGCAATGTCAAAGGGCGGCATTCTC
ATCGAATATGGCGGGTTGAGCGTCGAGCCGACGCCGTTCCCTCTGGCTGCCGTCTTGGGAAAGACGCTGACGCTGCGTGG
TTATCTCGTGCACGAGATCACCGGCAACCCAGAGAAGCTGGAGGCCGCCAAGGCGTTTATCCTCGAAGGCCTGGAAACCG
GAACGCTGAGGCCGATCATCGACAGGACCTTTGCGCTCGACCAGATCGTCGAGGCGCACCGGTACCTCGAATCGAACGAG
CAGTTCGGCAAGATCGTTGTGACGGTCTGA

Upstream 100 bases:

>100_bases
TCGAAACCTCTGGTTTCTACTGCTTTATCCCTACGCCCATTTATCCATGAAGCCTTTGGCTGCATAGCTCATTCGGTTCA
GATAATTTGGAGTAACCCGA

Downstream 100 bases:

>100_bases
GCAAGGGCAAGGCTGAACAAATCATTCCTGCCGGCAATATCGCCCTTGAAGGCCCGGCTCCGCATTCCTAACTGTCTGGT
GCGGGCCGGGCCCCTCTGAC

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MARIVRFHQHGGPEVLGIEDIDLPPPAPGEVQIRVKALGLNRAEALLRAGSYIETPPLPSGLGLEAAGVVETVGEGVKDF
VPGDAVSVIPPQSMVCWPAYGEVVAYPAGLIVKHPSSLDWQTAAAVWMQYLTAYGALIDIARLSSGDAVVITAASSSVGL
AAIQIANKIGATAIAVTRTSVKKQALLDAGAAHVVVLAEEDLAARLSEIAGPQAVRVVLDAIGGPIFEPLTAAMSKGGIL
IEYGGLSVEPTPFPLAAVLGKTLTLRGYLVHEITGNPEKLEAAKAFILEGLETGTLRPIIDRTFALDQIVEAHRYLESNE
QFGKIVVTV

Sequences:

>Translated_329_residues
MARIVRFHQHGGPEVLGIEDIDLPPPAPGEVQIRVKALGLNRAEALLRAGSYIETPPLPSGLGLEAAGVVETVGEGVKDF
VPGDAVSVIPPQSMVCWPAYGEVVAYPAGLIVKHPSSLDWQTAAAVWMQYLTAYGALIDIARLSSGDAVVITAASSSVGL
AAIQIANKIGATAIAVTRTSVKKQALLDAGAAHVVVLAEEDLAARLSEIAGPQAVRVVLDAIGGPIFEPLTAAMSKGGIL
IEYGGLSVEPTPFPLAAVLGKTLTLRGYLVHEITGNPEKLEAAKAFILEGLETGTLRPIIDRTFALDQIVEAHRYLESNE
QFGKIVVTV
>Mature_328_residues
ARIVRFHQHGGPEVLGIEDIDLPPPAPGEVQIRVKALGLNRAEALLRAGSYIETPPLPSGLGLEAAGVVETVGEGVKDFV
PGDAVSVIPPQSMVCWPAYGEVVAYPAGLIVKHPSSLDWQTAAAVWMQYLTAYGALIDIARLSSGDAVVITAASSSVGLA
AIQIANKIGATAIAVTRTSVKKQALLDAGAAHVVVLAEEDLAARLSEIAGPQAVRVVLDAIGGPIFEPLTAAMSKGGILI
EYGGLSVEPTPFPLAAVLGKTLTLRGYLVHEITGNPEKLEAAKAFILEGLETGTLRPIIDRTFALDQIVEAHRYLESNEQ
FGKIVVTV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=319, Percent_Identity=30.0940438871473, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI13236495, Length=319, Percent_Identity=30.0940438871473, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=31.9402985074627, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=31.9402985074627, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=27.0700636942675, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI194239676, Length=314, Percent_Identity=29.6178343949045, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI24308257, Length=357, Percent_Identity=25.7703081232493, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI67078404, Length=280, Percent_Identity=29.6428571428571, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI67078406, Length=243, Percent_Identity=32.9218106995885, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI28557745, Length=334, Percent_Identity=26.3473053892216, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI90669511, Length=169, Percent_Identity=33.1360946745562, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=32.7217125382263, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1788073, Length=242, Percent_Identity=26.0330578512397, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI226510941, Length=329, Percent_Identity=23.7082066869301, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536829, Length=276, Percent_Identity=28.6231884057971, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=347, Percent_Identity=25.6484149855908, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17556000, Length=277, Percent_Identity=25.6317689530686, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=331, Percent_Identity=26.8882175226586, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI45550423, Length=309, Percent_Identity=29.4498381877023, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581345, Length=230, Percent_Identity=25.2173913043478, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34396; Mature: 34265

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIVRFHQHGGPEVLGIEDIDLPPPAPGEVQIRVKALGLNRAEALLRAGSYIETPPLPS
CCCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCCC
GLGLEAAGVVETVGEGVKDFVPGDAVSVIPPQSMVCWPAYGEVVAYPAGLIVKHPSSLDW
CCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCEEEECCCCCEEECCCCEEEECCCCCCH
QTAAAVWMQYLTAYGALIDIARLSSGDAVVITAASSSVGLAAIQIANKIGATAIAVTRTS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEHHH
VKKQALLDAGAAHVVVLAEEDLAARLSEIAGPQAVRVVLDAIGGPIFEPLTAAMSKGGIL
HHHHHHHCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEE
IEYGGLSVEPTPFPLAAVLGKTLTLRGYLVHEITGNPEKLEAAKAFILEGLETGTLRPII
EEECCEECCCCCCHHHHHHCCCEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHH
DRTFALDQIVEAHRYLESNEQFGKIVVTV
HHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
ARIVRFHQHGGPEVLGIEDIDLPPPAPGEVQIRVKALGLNRAEALLRAGSYIETPPLPS
CCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCCC
GLGLEAAGVVETVGEGVKDFVPGDAVSVIPPQSMVCWPAYGEVVAYPAGLIVKHPSSLDW
CCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCEEEECCCCCEEECCCCEEEECCCCCCH
QTAAAVWMQYLTAYGALIDIARLSSGDAVVITAASSSVGLAAIQIANKIGATAIAVTRTS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEHHH
VKKQALLDAGAAHVVVLAEEDLAARLSEIAGPQAVRVVLDAIGGPIFEPLTAAMSKGGIL
HHHHHHHCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEE
IEYGGLSVEPTPFPLAAVLGKTLTLRGYLVHEITGNPEKLEAAKAFILEGLETGTLRPII
EEECCEECCCCCCHHHHHHCCCEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHH
DRTFALDQIVEAHRYLESNEQFGKIVVTV
HHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]