Definition Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession NC_002678
Length 7,036,071

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The map label for this gene is gno [H]

Identifier: 13475920

GI number: 13475920

Start: 5864196

End: 5864969

Strand: Direct

Name: gno [H]

Synonym: mlr7106

Alternate gene names: 13475920

Gene position: 5864196-5864969 (Clockwise)

Preceding gene: 13475917

Following gene: 13475921

Centisome position: 83.34

GC content: 67.18

Gene sequence:

>774_bases
ATGCGCAATGCTTCTCTGTTCGATCTCGCCGGCAGGAAAGCGCTTGTCACCGGCGCCAGCCGCGGAATCGGCCGCAGCAT
CGCCGAGGCGTTGAGCGCTGCCGGCGCCGACGTCGCGGTCACCGCGCGCAGCCTGGCGTCCCTCGACGGGACCACGGCGG
CGATCCGTGCGGCCGGCGGGGTTGCGCATGCCGTCGCTCTCGACGTCACCGATGTCAACCGCTGCCGGACCGCCACCGCC
GAGGCTGCGGGCCTGCTCGGCGGTCTCGACATCCTCGTCAACAATGCCGGAATGGAAGAGGTCAGGCCTTCGCTCGACGT
CGACGAGGCGCTGTGGGACCGGATCGTCGACACCAATCTCAAGGGGGCGTTCTTCTGCGCCCAGGCGGCCGCGCGGCAGA
TGCGGGATGCCGGGCATGGCGGCGCCATCATCAATCTCTGCTCGCTGACGTCAGAAGTCGGCATTCCTACCGCGGTGCCC
TATGGCTCTTCGAAGTCGGGCCTGCTCGGCATGACCAGGGCGCTGGCGGCGGAGTGGGCGGGTCTCGGCATTAGGGTCAA
CGCCATCGCCCCGGGTTACTTCCGGACGGCGATGACCGATGTGTTCTACAGCAACGAGGCATGGCAGCAGTCTATGCTCG
CCAAGATCCCGCAGCACCGTTTCGGCGATCTCGGCGACCTGCACGGCGTTGCCGTCTTCCTTGCCTCGGATGCGGCGGCC
TACATAACCGGCCAGTCCATTCCGGTGGATGGCGGCTTCCTGGCATCGATTTGA

Upstream 100 bases:

>100_bases
GAGTAGCGTAGCCGAAACCGTTTGTATATGCTTGTATATGTAACTTGATCTGGTAGTCTCTCTATGCGAACGGAAGCGCG
ACACCGGCAAGGAGGATCAC

Downstream 100 bases:

>100_bases
GGCAGCGCTAAAGGTTCGAAATCAACGTCTTGCGCAACGTAACCGGCCGGCGCGTTGCGTTCCAACAAAGAGGAACATCC
ATGTCCGACGTCAGCTTCCA

Product: dehydrogenase

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRNASLFDLAGRKALVTGASRGIGRSIAEALSAAGADVAVTARSLASLDGTTAAIRAAGGVAHAVALDVTDVNRCRTATA
EAAGLLGGLDILVNNAGMEEVRPSLDVDEALWDRIVDTNLKGAFFCAQAAARQMRDAGHGGAIINLCSLTSEVGIPTAVP
YGSSKSGLLGMTRALAAEWAGLGIRVNAIAPGYFRTAMTDVFYSNEAWQQSMLAKIPQHRFGDLGDLHGVAVFLASDAAA
YITGQSIPVDGGFLASI

Sequences:

>Translated_257_residues
MRNASLFDLAGRKALVTGASRGIGRSIAEALSAAGADVAVTARSLASLDGTTAAIRAAGGVAHAVALDVTDVNRCRTATA
EAAGLLGGLDILVNNAGMEEVRPSLDVDEALWDRIVDTNLKGAFFCAQAAARQMRDAGHGGAIINLCSLTSEVGIPTAVP
YGSSKSGLLGMTRALAAEWAGLGIRVNAIAPGYFRTAMTDVFYSNEAWQQSMLAKIPQHRFGDLGDLHGVAVFLASDAAA
YITGQSIPVDGGFLASI
>Mature_257_residues
MRNASLFDLAGRKALVTGASRGIGRSIAEALSAAGADVAVTARSLASLDGTTAAIRAAGGVAHAVALDVTDVNRCRTATA
EAAGLLGGLDILVNNAGMEEVRPSLDVDEALWDRIVDTNLKGAFFCAQAAARQMRDAGHGGAIINLCSLTSEVGIPTAVP
YGSSKSGLLGMTRALAAEWAGLGIRVNAIAPGYFRTAMTDVFYSNEAWQQSMLAKIPQHRFGDLGDLHGVAVFLASDAAA
YITGQSIPVDGGFLASI

Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=36.0323886639676, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=34.6938775510204, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=32.5490196078431, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=30.8035714285714, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=32.3770491803279, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=33.6, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=36.25, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.0483870967742, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=34.2723004694836, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=30.2788844621514, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=34.0659340659341, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.4742268041237, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI209862901, Length=252, Percent_Identity=29.3650793650794, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI19923983, Length=252, Percent_Identity=29.3650793650794, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI59889578, Length=195, Percent_Identity=31.7948717948718, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI210032110, Length=197, Percent_Identity=27.9187817258883, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=29.296875, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=33.7209302325581, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI32455239, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI5031765, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40254986, Length=192, Percent_Identity=32.2916666666667, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4504505, Length=195, Percent_Identity=33.8461538461538, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=38.5321100917431, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=191, Percent_Identity=24.0837696335079, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI109715829, Length=192, Percent_Identity=28.6458333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=38.6454183266932, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=34.5238095238095, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=38.4, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=37.6518218623482, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=37.1900826446281, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=35.4581673306773, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=33.9920948616601, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=33.8582677165354, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=31.1787072243346, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=29.0836653386454, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=30.3149606299213, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787545, Length=254, Percent_Identity=29.1338582677165, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=34.3873517786561, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=33.0677290836653, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=30.2040816326531, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=31.1740890688259, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17561272, Length=249, Percent_Identity=33.7349397590361, Blast_Score=106, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=32.8301886792453, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=32.319391634981, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=28.90625, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=30.0813008130081, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=27.734375, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=31.203007518797, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI86565303, Length=209, Percent_Identity=32.0574162679426, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=30.2681992337165, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=30.9701492537313, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=29.5918367346939, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=30.2681992337165, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=27.4809160305344, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=31.1787072243346, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=31.1787072243346, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=34.2592592592593, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.2030651340996, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=27.5303643724696, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=28.1853281853282, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=29.0566037735849, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997099, Length=228, Percent_Identity=31.140350877193, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=30.5970149253731, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=31.8007662835249, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=26.1538461538462, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=30.2083333333333, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=28.6792452830189, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=25.8883248730964, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=30.9644670050761, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558628, Length=200, Percent_Identity=31, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=27.5092936802974, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=29.718875502008, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=29.5719844357977, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=198, Percent_Identity=28.2828282828283, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=25.130890052356, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=27.4193548387097, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=227, Percent_Identity=30.3964757709251, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=199, Percent_Identity=31.6582914572864, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=34.8, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=32.4, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32.8, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=30.5220883534137, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=30.7086614173228, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=31.6872427983539, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=31.1740890688259, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21357673, Length=200, Percent_Identity=33.5, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=29.0836653386454, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641232, Length=230, Percent_Identity=29.5652173913043, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=34.7368421052632, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=28.125, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737361, Length=196, Percent_Identity=30.1020408163265, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281364892, Length=172, Percent_Identity=29.0697674418605, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007234, Length=199, Percent_Identity=31.1557788944724, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584752, Length=197, Percent_Identity=28.4263959390863, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 26362; Mature: 26362

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNASLFDLAGRKALVTGASRGIGRSIAEALSAAGADVAVTARSLASLDGTTAAIRAAGG
CCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCC
VAHAVALDVTDVNRCRTATAEAAGLLGGLDILVNNAGMEEVRPSLDVDEALWDRIVDTNL
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCCCHHHHHHHHHHCCCC
KGAFFCAQAAARQMRDAGHGGAIINLCSLTSEVGIPTAVPYGSSKSGLLGMTRALAAEWA
CHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GLGIRVNAIAPGYFRTAMTDVFYSNEAWQQSMLAKIPQHRFGDLGDLHGVAVFLASDAAA
CCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCCCHHHEEEEEECCCEE
YITGQSIPVDGGFLASI
EEECCCCCCCCCEECCC
>Mature Secondary Structure
MRNASLFDLAGRKALVTGASRGIGRSIAEALSAAGADVAVTARSLASLDGTTAAIRAAGG
CCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCC
VAHAVALDVTDVNRCRTATAEAAGLLGGLDILVNNAGMEEVRPSLDVDEALWDRIVDTNL
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCCCHHHHHHHHHHCCCC
KGAFFCAQAAARQMRDAGHGGAIINLCSLTSEVGIPTAVPYGSSKSGLLGMTRALAAEWA
CHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GLGIRVNAIAPGYFRTAMTDVFYSNEAWQQSMLAKIPQHRFGDLGDLHGVAVFLASDAAA
CCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCCCHHHEEEEEECCCEE
YITGQSIPVDGGFLASI
EEECCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751271 [H]