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The map label for this gene is dgoR [H]

Identifier: 13475898

GI number: 13475898

Start: 5842125

End: 5842931

Strand: Reverse

Name: dgoR [H]

Synonym: mll7079

Alternate gene names: 13475898

Gene position: 5842931-5842125 (Counterclockwise)

Preceding gene: 13475899

Following gene: 13475897

Centisome position: 83.04

GC content: 63.94

Gene sequence:

>807_bases
ATGACGATGGACGCGGCGACCGCTGTGAGCGATCAAGGCAAGCAGGACCTTCCTGCCGGAGATGGCGCCACACTGTCCCT
GAAGGATCGCATCGCACGCGATCTTGGACAGCGCATTCTCGCCGGCATCTACGCGCAGCACGCGGTCCTGCCGACGGAGG
CTGAACTGTGCGTCATCTACGGCGCCAGCCGCACGGCGCTACGCGATGCGCTGCTGACACTTTCGGCCAAGGGACTGATC
GAGGCACGCAAGCGGGCTGGCACGCGCGTGCGCGTGTCGAGCGAATGGAACAGGCTTGATGCGCAGGTTCTCGAATGGAT
GCGCGATATCGAGCCTGATCTCGATTTCGTCCGCGGCTTGATCGAGGCACGGCTGGTCATCGAGCCGGCTGCCGCCCAGC
TTGCGGCCAAGATGGCGACCTCGGGCGATCTCGCGGTGATCGAAGCCGCCTATGAGGCCATGCGCATTGCGCCGGAGGAC
GACCTCGCGGCCTGTCTCGATGCCGATGTCCGCTTTCATACCGCCATCCTGCGCGCCAGCCGCAACCCGGTTTTCGCCAA
TCTCGGCAATATGCTGGCAGCCGCGCTTAGCTTCTCTTTCCGACTGACCACATCGGCCACCGCCAACTATCAGCAGACGC
TCAGCGCCCATGGCGATGTGCTGGAAGCGATCCGCATGCGTAGAGTCGACGATGCTCACGACCAGATGAAAGCGCTGATC
GGCATCGCCTCGAACGACCTTCTCGCCGTCGCTCGCAAGGGCCGCCACCAACAGCCGGTCCCTACTGCCAGTGCCGATCC
CATCTGA

Upstream 100 bases:

>100_bases
GAATGATACTGACGTCCGTGCCAACCTTCTATCAATTGCTGGCAAAAGGCTCACTGCTGATCCTTGCTGTGGTCATTGCC
GAGTACCACTTGAACAGGAC

Downstream 100 bases:

>100_bases
GTTTGACGACCCGGACCATTGAAATTCGAAATGGCCACCTGTCCGCCGAAATCGTTCCGTCGCTTGGCGCTGGTCTGGCG
CGGTTCGACCGTGGCCGCCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTMDAATAVSDQGKQDLPAGDGATLSLKDRIARDLGQRILAGIYAQHAVLPTEAELCVIYGASRTALRDALLTLSAKGLI
EARKRAGTRVRVSSEWNRLDAQVLEWMRDIEPDLDFVRGLIEARLVIEPAAAQLAAKMATSGDLAVIEAAYEAMRIAPED
DLAACLDADVRFHTAILRASRNPVFANLGNMLAAALSFSFRLTTSATANYQQTLSAHGDVLEAIRMRRVDDAHDQMKALI
GIASNDLLAVARKGRHQQPVPTASADPI

Sequences:

>Translated_268_residues
MTMDAATAVSDQGKQDLPAGDGATLSLKDRIARDLGQRILAGIYAQHAVLPTEAELCVIYGASRTALRDALLTLSAKGLI
EARKRAGTRVRVSSEWNRLDAQVLEWMRDIEPDLDFVRGLIEARLVIEPAAAQLAAKMATSGDLAVIEAAYEAMRIAPED
DLAACLDADVRFHTAILRASRNPVFANLGNMLAAALSFSFRLTTSATANYQQTLSAHGDVLEAIRMRRVDDAHDQMKALI
GIASNDLLAVARKGRHQQPVPTASADPI
>Mature_267_residues
TMDAATAVSDQGKQDLPAGDGATLSLKDRIARDLGQRILAGIYAQHAVLPTEAELCVIYGASRTALRDALLTLSAKGLIE
ARKRAGTRVRVSSEWNRLDAQVLEWMRDIEPDLDFVRGLIEARLVIEPAAAQLAAKMATSGDLAVIEAAYEAMRIAPEDD
LAACLDADVRFHTAILRASRNPVFANLGNMLAAALSFSFRLTTSATANYQQTLSAHGDVLEAIRMRRVDDAHDQMKALIG
IASNDLLAVARKGRHQQPVPTASADPI

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=223, Percent_Identity=38.5650224215247, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI48994961, Length=216, Percent_Identity=31.9444444444444, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790032, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789353, Length=161, Percent_Identity=32.2981366459627, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786303, Length=214, Percent_Identity=30.3738317757009, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28868; Mature: 28737

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMDAATAVSDQGKQDLPAGDGATLSLKDRIARDLGQRILAGIYAQHAVLPTEAELCVIY
CCCCHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
GASRTALRDALLTLSAKGLIEARKRAGTRVRVSSEWNRLDAQVLEWMRDIEPDLDFVRGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHH
IEARLVIEPAAAQLAAKMATSGDLAVIEAAYEAMRIAPEDDLAACLDADVRFHTAILRAS
HHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHC
RNPVFANLGNMLAAALSFSFRLTTSATANYQQTLSAHGDVLEAIRMRRVDDAHDQMKALI
CCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GIASNDLLAVARKGRHQQPVPTASADPI
HCCCCHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TMDAATAVSDQGKQDLPAGDGATLSLKDRIARDLGQRILAGIYAQHAVLPTEAELCVIY
CCCHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
GASRTALRDALLTLSAKGLIEARKRAGTRVRVSSEWNRLDAQVLEWMRDIEPDLDFVRGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHH
IEARLVIEPAAAQLAAKMATSGDLAVIEAAYEAMRIAPEDDLAACLDADVRFHTAILRAS
HHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHC
RNPVFANLGNMLAAALSFSFRLTTSATANYQQTLSAHGDVLEAIRMRRVDDAHDQMKALI
CCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GIASNDLLAVARKGRHQQPVPTASADPI
HCCCCHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]