Click here to switch to the map view.

The map label for this gene is gatA [H]

Identifier: 13475889

GI number: 13475889

Start: 5829683

End: 5831542

Strand: Direct

Name: gatA [H]

Synonym: mlr7070

Alternate gene names: 13475889

Gene position: 5829683-5831542 (Clockwise)

Preceding gene: 13475888

Following gene: 13475890

Centisome position: 82.85

GC content: 66.88

Gene sequence:

>1860_bases
ATGAGTGATGTCCACTTCGACATAGCGAGCCTGCACGCGGCCTATCGGGACGGCGTCGGCGTTGGCGATGTGATTGCGAC
GATTTATGCCCGCATCGAGGCAGCCGATGATCCGGGCATATTCATCCATCTCGTCAGCAAGGCGAACCTCCTTACCGCGG
CCGAGGCGCTCGGCCCGTTCGACCCGGCGGCAAAACCACTGTGGGGTATTCCCTTCGCCGTCAAGGACAACATCGACGTC
GCAGGCATGCCGACGACGGCGGCCTGCGCCGAATACACCTACTGGCCCGACGAGGACGCCACCGTGGTGGCGCGGCTGAA
GGCCGCCGGGGCGCTGGTGGTCGGCAAGACCAATCTCGACCAGTTCGCCACCGGCCTTGTCGGCGTGCGCACGCCCTATC
CGATCCCGCGCAACGCCATCGACGCGGAGCTGGTGCCGGGCGGCTCCTCCTCGGGGTCGGCGGTGGCCACGGCGCGTGGC
ATCGTTTCCTTCGCGCTCGGCACCGACACCGCCGGCTCCGGCCGCATTCCCGCCGGCCTCAACAACATCGTCGGGCTGAA
GCCAACCGTCGGTGCATTGTCGACGGGCGGCGTCGTGCCGGCCTGCCGCACGCTCGACTGCGTGTCGGTGTTCGCGCTGA
CCGTCGACGACGCCTATGCAGTGTTCTCCGTCGCAGCAGCGCGCGATGCGGCCGATCCCTATTCGCGCGACATCGCCGTC
CAGCCGCTCGCCGCGCGCCCGCCGGTGCTGAGCGTCGGTATCCCGGCAAAAGCCGACCTGAAGTTCTTCGGCGATGTGGC
GATGCAGGCCGGCTTCGAGGCCTCGCTCGCTATGCTGTCGCGGCTCGGCTGCCGGCTGGTCGAAATCCCGTTCGGCGATT
TCTACGCCACCGCCAACCTGCTCTATGAGGGCGCCTGGGTGGCCGAACGCTATGCCGCGATCCGCGATTTCATGGAAGCC
AACGAAGCCGCCATGCATCCGGTGACGCGCAAGATCATCGGCGGCGCTAGGAAGCTGTCAGCGGCGGACGCCTTCCGCGG
CCTCTATGCCTTGCAGGCCTACCGGGCCAAGCTCGCCGCGGTCATCGCCTCGGTTGACCTGTTCTGCGTGCCGACCGCGC
CGACGCATTACACCGCCGCCGCCGTGCTCGCCGATCCGGTCGAGACCAACAGCCGGCTCGGCACCTACACCAATTTCGTC
AACCTGCTCGACATGTGCGGCATCGCCGTTCCCACAGGCAAGCGCGACGACGGGCTGCCGATGAGCGTGACCTTGCTGGC
ACCGGCCGGCCGCGACGTGCTGACGGCGATGCTTGCCCGCGACTTACATGTGCAGAGCGGCCTTTCGCTCGGCGCCACGG
GCTGGCCGCAGCCCAACCTGCAGCCGGTGGCCGCGCCGCCCTGCGACGGCATGATCGATCTGGTGGTGGTCGGCGCGCAT
TTGTCGGGCATGCCGCTCAACGGCCAGCTCAACCAGCTCGGAGCGCAATTCCTGCGTGCTACAAAGACGGCCGCCGCCTA
TAGACTCTATGCTCTGGCTGGCCAGTCCGTGCCCAAGCCTGGCTTGATCCGCGTTGCCGATGGCGGCACGCGGATCGACG
TCGAGATCTGGCGGCTCGAGCCGGAGGCCTTCGGACGTTTCGTTGCCGCTATTCCCGCACCGCTCGGCATCGGCACGGTC
GAACTCGACGACGGCACCCCGGCCAAAGGCTTTCTAGTCGAAACCGCTGGCTTGGACGGTGCCTCTGATATCTCCTCATT
AGGCGGCTGGCGCCGCTTTGTCGCACGTAATAGGGACATGGCCGACCAAATTGATCAGCAGCGCAATTCTCCCGACACCG
GTGGGCACGTTGCGCTATGA

Upstream 100 bases:

>100_bases
TCCTCAATCCGGTCGGGACCGAGCATTCGGTGTGGACGAAGGACGGCTGCGTCGTGCTGATCCAGTGGGACCTGCCGGTT
ATCATTCTGGGGGAGACGAA

Downstream 100 bases:

>100_bases
CCAGCAGGGTGTGCGTGAGAGCGCCGTGTTTGAATATGATTCAGGCTGGCTGCGCAGGCAACTCATTCGCCGGATTTTGC
AGTAAACATCCATACTGGAA

Product: allophanate hydrolase

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MSDVHFDIASLHAAYRDGVGVGDVIATIYARIEAADDPGIFIHLVSKANLLTAAEALGPFDPAAKPLWGIPFAVKDNIDV
AGMPTTAACAEYTYWPDEDATVVARLKAAGALVVGKTNLDQFATGLVGVRTPYPIPRNAIDAELVPGGSSSGSAVATARG
IVSFALGTDTAGSGRIPAGLNNIVGLKPTVGALSTGGVVPACRTLDCVSVFALTVDDAYAVFSVAAARDAADPYSRDIAV
QPLAARPPVLSVGIPAKADLKFFGDVAMQAGFEASLAMLSRLGCRLVEIPFGDFYATANLLYEGAWVAERYAAIRDFMEA
NEAAMHPVTRKIIGGARKLSAADAFRGLYALQAYRAKLAAVIASVDLFCVPTAPTHYTAAAVLADPVETNSRLGTYTNFV
NLLDMCGIAVPTGKRDDGLPMSVTLLAPAGRDVLTAMLARDLHVQSGLSLGATGWPQPNLQPVAAPPCDGMIDLVVVGAH
LSGMPLNGQLNQLGAQFLRATKTAAAYRLYALAGQSVPKPGLIRVADGGTRIDVEIWRLEPEAFGRFVAAIPAPLGIGTV
ELDDGTPAKGFLVETAGLDGASDISSLGGWRRFVARNRDMADQIDQQRNSPDTGGHVAL

Sequences:

>Translated_619_residues
MSDVHFDIASLHAAYRDGVGVGDVIATIYARIEAADDPGIFIHLVSKANLLTAAEALGPFDPAAKPLWGIPFAVKDNIDV
AGMPTTAACAEYTYWPDEDATVVARLKAAGALVVGKTNLDQFATGLVGVRTPYPIPRNAIDAELVPGGSSSGSAVATARG
IVSFALGTDTAGSGRIPAGLNNIVGLKPTVGALSTGGVVPACRTLDCVSVFALTVDDAYAVFSVAAARDAADPYSRDIAV
QPLAARPPVLSVGIPAKADLKFFGDVAMQAGFEASLAMLSRLGCRLVEIPFGDFYATANLLYEGAWVAERYAAIRDFMEA
NEAAMHPVTRKIIGGARKLSAADAFRGLYALQAYRAKLAAVIASVDLFCVPTAPTHYTAAAVLADPVETNSRLGTYTNFV
NLLDMCGIAVPTGKRDDGLPMSVTLLAPAGRDVLTAMLARDLHVQSGLSLGATGWPQPNLQPVAAPPCDGMIDLVVVGAH
LSGMPLNGQLNQLGAQFLRATKTAAAYRLYALAGQSVPKPGLIRVADGGTRIDVEIWRLEPEAFGRFVAAIPAPLGIGTV
ELDDGTPAKGFLVETAGLDGASDISSLGGWRRFVARNRDMADQIDQQRNSPDTGGHVAL
>Mature_618_residues
SDVHFDIASLHAAYRDGVGVGDVIATIYARIEAADDPGIFIHLVSKANLLTAAEALGPFDPAAKPLWGIPFAVKDNIDVA
GMPTTAACAEYTYWPDEDATVVARLKAAGALVVGKTNLDQFATGLVGVRTPYPIPRNAIDAELVPGGSSSGSAVATARGI
VSFALGTDTAGSGRIPAGLNNIVGLKPTVGALSTGGVVPACRTLDCVSVFALTVDDAYAVFSVAAARDAADPYSRDIAVQ
PLAARPPVLSVGIPAKADLKFFGDVAMQAGFEASLAMLSRLGCRLVEIPFGDFYATANLLYEGAWVAERYAAIRDFMEAN
EAAMHPVTRKIIGGARKLSAADAFRGLYALQAYRAKLAAVIASVDLFCVPTAPTHYTAAAVLADPVETNSRLGTYTNFVN
LLDMCGIAVPTGKRDDGLPMSVTLLAPAGRDVLTAMLARDLHVQSGLSLGATGWPQPNLQPVAAPPCDGMIDLVVVGAHL
SGMPLNGQLNQLGAQFLRATKTAAAYRLYALAGQSVPKPGLIRVADGGTRIDVEIWRLEPEAFGRFVAAIPAPLGIGTVE
LDDGTPAKGFLVETAGLDGASDISSLGGWRRFVARNRDMADQIDQQRNSPDTGGHVAL

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=444, Percent_Identity=25.6756756756757, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI195972892, Length=136, Percent_Identity=33.8235294117647, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17543272, Length=411, Percent_Identity=28.9537712895377, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17556264, Length=279, Percent_Identity=28.673835125448, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17537465, Length=169, Percent_Identity=31.9526627218935, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319685, Length=570, Percent_Identity=44.9122807017544, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6323950, Length=254, Percent_Identity=36.2204724409449, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648113, Length=181, Percent_Identity=40.3314917127072, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356731, Length=429, Percent_Identity=24.7086247086247, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648441, Length=427, Percent_Identity=22.4824355971897, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648439, Length=427, Percent_Identity=22.4824355971897, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24652985, Length=138, Percent_Identity=34.0579710144928, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922090, Length=138, Percent_Identity=34.0579710144928, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24652981, Length=138, Percent_Identity=34.0579710144928, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24652983, Length=138, Percent_Identity=34.0579710144928, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648435, Length=427, Percent_Identity=22.4824355971897, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648437, Length=427, Percent_Identity=22.4824355971897, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: 6.3.5.-

Molecular weight: Translated: 64448; Mature: 64317

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVHFDIASLHAAYRDGVGVGDVIATIYARIEAADDPGIFIHLVSKANLLTAAEALGPF
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCC
DPAAKPLWGIPFAVKDNIDVAGMPTTAACAEYTYWPDEDATVVARLKAAGALVVGKTNLD
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCEEEEHHHCCEEEEECCCHH
QFATGLVGVRTPYPIPRNAIDAELVPGGSSSGSAVATARGIVSFALGTDTAGSGRIPAGL
HHHHHHEECCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCCCC
NNIVGLKPTVGALSTGGVVPACRTLDCVSVFALTVDDAYAVFSVAAARDAADPYSRDIAV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCCCEEE
QPLAARPPVLSVGIPAKADLKFFGDVAMQAGFEASLAMLSRLGCRLVEIPFGDFYATANL
CCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCHHHHHHHH
LYEGAWVAERYAAIRDFMEANEAAMHPVTRKIIGGARKLSAADAFRGLYALQAYRAKLAA
HHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIASVDLFCVPTAPTHYTAAAVLADPVETNSRLGTYTNFVNLLDMCGIAVPTGKRDDGLP
HHHHCEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEECCCCCCCCCCC
MSVTLLAPAGRDVLTAMLARDLHVQSGLSLGATGWPQPNLQPVAAPPCDGMIDLVVVGAH
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
LSGMPLNGQLNQLGAQFLRATKTAAAYRLYALAGQSVPKPGLIRVADGGTRIDVEIWRLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCEEEEEEEEEC
PEAFGRFVAAIPAPLGIGTVELDDGTPAKGFLVETAGLDGASDISSLGGWRRFVARNRDM
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCH
ADQIDQQRNSPDTGGHVAL
HHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SDVHFDIASLHAAYRDGVGVGDVIATIYARIEAADDPGIFIHLVSKANLLTAAEALGPF
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCC
DPAAKPLWGIPFAVKDNIDVAGMPTTAACAEYTYWPDEDATVVARLKAAGALVVGKTNLD
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCEEEEHHHCCEEEEECCCHH
QFATGLVGVRTPYPIPRNAIDAELVPGGSSSGSAVATARGIVSFALGTDTAGSGRIPAGL
HHHHHHEECCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCCCC
NNIVGLKPTVGALSTGGVVPACRTLDCVSVFALTVDDAYAVFSVAAARDAADPYSRDIAV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCCCEEE
QPLAARPPVLSVGIPAKADLKFFGDVAMQAGFEASLAMLSRLGCRLVEIPFGDFYATANL
CCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCHHHHHHHH
LYEGAWVAERYAAIRDFMEANEAAMHPVTRKIIGGARKLSAADAFRGLYALQAYRAKLAA
HHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIASVDLFCVPTAPTHYTAAAVLADPVETNSRLGTYTNFVNLLDMCGIAVPTGKRDDGLP
HHHHCEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEECCCCCCCCCCC
MSVTLLAPAGRDVLTAMLARDLHVQSGLSLGATGWPQPNLQPVAAPPCDGMIDLVVVGAH
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
LSGMPLNGQLNQLGAQFLRATKTAAAYRLYALAGQSVPKPGLIRVADGGTRIDVEIWRLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCEEEEEEEEEC
PEAFGRFVAAIPAPLGIGTVELDDGTPAKGFLVETAGLDGASDISSLGGWRRFVARNRDM
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCH
ADQIDQQRNSPDTGGHVAL
HHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA