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The map label for this gene is lrp [H]

Identifier: 13475855

GI number: 13475855

Start: 5796095

End: 5796604

Strand: Direct

Name: lrp [H]

Synonym: mlr7030

Alternate gene names: 13475855

Gene position: 5796095-5796604 (Clockwise)

Preceding gene: 13475853

Following gene: 13475864

Centisome position: 82.38

GC content: 56.47

Gene sequence:

>510_bases
TTGTGCTGTGGCATGCGTTCTGCGGAGACGACCGTGAAACTGGATCGGATCGACATCAAGATTCTGTACGAATTGCAGAA
GAACGGCCGCATCACCAATGTGGAACTGGCTGAACTGGTGCATCTGTCGCCGAGCCCGTGCCTTATGCGGGTCAAGAGAC
TGCAATCGGAGGGCTACATCGAGGGCTATTCCGCGCAGATCAACATCGGCAAGCTTGGCCAGACGCTGACCGTGTTCACC
GAAATCACCTTGAAGAACCATCGCCAGGTCGACTTCGCCCGCTTTCTCGCCGTCGTCGAGAAGATCGACCAGGTCATCGA
ATGCCACCTCGTGTCGGGCGGCTACGACTATTTGATGAAATTCGTGACCGCCGGCATAGCCGAGTACCAGACGATCATGG
AGCGGCTGACCGACATGGATATCGGCATCGACAAGTATTTCAGCTTCGTGGTGCTGAAGTCGCCAATCGTCAAGGCGCAC
ATGCCGCTGCCCAGCCTGTTTCCGAGGTGA

Upstream 100 bases:

>100_bases
CGGTCGAAATCGGGAGCCTCTGCGTTTCAAAGCGCGGTCCGCTTGGATGGACAGGCCAAAGGGCTGTGGTAGTGTTTATG
TCCATGGGCAAGGCAGCATT

Downstream 100 bases:

>100_bases
GCCTCTGCCGTTTTGTCAGCGATGGCCGTACTGGCTGACCAACTCGGGATCGCGGACGAGGCCGTCGAGCCACGTCGGGT
CAAGCTTCGGGACGGAGGAG

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MCCGMRSAETTVKLDRIDIKILYELQKNGRITNVELAELVHLSPSPCLMRVKRLQSEGYIEGYSAQINIGKLGQTLTVFT
EITLKNHRQVDFARFLAVVEKIDQVIECHLVSGGYDYLMKFVTAGIAEYQTIMERLTDMDIGIDKYFSFVVLKSPIVKAH
MPLPSLFPR

Sequences:

>Translated_169_residues
MCCGMRSAETTVKLDRIDIKILYELQKNGRITNVELAELVHLSPSPCLMRVKRLQSEGYIEGYSAQINIGKLGQTLTVFT
EITLKNHRQVDFARFLAVVEKIDQVIECHLVSGGYDYLMKFVTAGIAEYQTIMERLTDMDIGIDKYFSFVVLKSPIVKAH
MPLPSLFPR
>Mature_169_residues
MCCGMRSAETTVKLDRIDIKILYELQKNGRITNVELAELVHLSPSPCLMRVKRLQSEGYIEGYSAQINIGKLGQTLTVFT
EITLKNHRQVDFARFLAVVEKIDQVIECHLVSGGYDYLMKFVTAGIAEYQTIMERLTDMDIGIDKYFSFVVLKSPIVKAH
MPLPSLFPR

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=140, Percent_Identity=44.2857142857143, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=31.3333333333333, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790182, Length=150, Percent_Identity=28, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 19219; Mature: 19219

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCCGMRSAETTVKLDRIDIKILYELQKNGRITNVELAELVHLSPSPCLMRVKRLQSEGYI
CCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCE
EGYSAQINIGKLGQTLTVFTEITLKNHRQVDFARFLAVVEKIDQVIECHLVSGGYDYLMK
ECCEEEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FVTAGIAEYQTIMERLTDMDIGIDKYFSFVVLKSPIVKAHMPLPSLFPR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEECCCCCCCCCC
>Mature Secondary Structure
MCCGMRSAETTVKLDRIDIKILYELQKNGRITNVELAELVHLSPSPCLMRVKRLQSEGYI
CCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCE
EGYSAQINIGKLGQTLTVFTEITLKNHRQVDFARFLAVVEKIDQVIECHLVSGGYDYLMK
ECCEEEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FVTAGIAEYQTIMERLTDMDIGIDKYFSFVVLKSPIVKAHMPLPSLFPR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]